KEGG   Capra hircus (goat): 100861386
Entry
100861386         CDS       T02910                                 

Gene name
KIT, SCFR
Definition
(RefSeq) KIT proto-oncogene receptor tyrosine kinase
  KO
K05091  proto-oncogene tyrosine-protein kinase Kit [EC:2.7.10.1]
Organism
chx  Capra hircus (goat)
Pathway
chx04010  MAPK signaling pathway
chx04014  Ras signaling pathway
chx04015  Rap1 signaling pathway
chx04072  Phospholipase D signaling pathway
chx04151  PI3K-Akt signaling pathway
chx04640  Hematopoietic cell lineage
chx04916  Melanogenesis
chx05200  Pathways in cancer
chx05221  Acute myeloid leukemia
chx05224  Breast cancer
chx05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:chx00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    100861386 (KIT)
   04014 Ras signaling pathway
    100861386 (KIT)
   04015 Rap1 signaling pathway
    100861386 (KIT)
   04072 Phospholipase D signaling pathway
    100861386 (KIT)
   04151 PI3K-Akt signaling pathway
    100861386 (KIT)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    100861386 (KIT)
  09152 Endocrine system
   04916 Melanogenesis
    100861386 (KIT)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100861386 (KIT)
   05230 Central carbon metabolism in cancer
    100861386 (KIT)
  09162 Cancer: specific types
   05221 Acute myeloid leukemia
    100861386 (KIT)
   05224 Breast cancer
    100861386 (KIT)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:chx01001]
    100861386 (KIT)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:chx04090]
    100861386 (KIT)
Enzymes [BR:chx01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100861386 (KIT)
Protein kinases [BR:chx01001]
 Receptor tyrosine kinases (RTK)
  PDGFR family [OT]
   100861386 (KIT)
CD molecules [BR:chx04090]
 Proteins
  100861386 (KIT)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Ig_3 I-set ig Ig_2 Ig_6 V-set C1-set Pkinase_fungal APH
Other DBs
NCBI-GeneID: 100861386
NCBI-ProteinID: NP_001272653
UniProt: Q28317
LinkDB
Position
6
AA seq 978 aa
MRGARGAWDFLFVLLLLLLVQTGSSQPSVSPGELSLPSIHPAKSELIVSVGDEIRLLCTD
PGFVKWTFEILGQLSEKTNPEWITEKAEATNTGNYTCTNKGGLSSSIYVFVRDPEKLFLI
DLPLYGKEENDTLVRCPLTDPEVTNYSLTGCEGKPLPKDLTFVADPKAGITIRNVKREYH
RLCLHCSANQKGKSMLSKKFTLKVRAAIKAVPVVSVSKTSYLLREGEEFAVTCLIKDVSS
SVDSMWIKENSQQSKAQTKKNSWHQGDFSYLRQERLTISSARVNDSGVFMCYANNTFGSA
NVTTTLEVVDKGFINIFPMMNTTVFVNDGENVDLVVEYEAYPKPEHRQWIYMNRTSTDKW
DDYPKSENESNIRYVNELHLTRLKGTEGGTYTFHVSNSDVNSSVTFNVNVNTKPEILTHD
RLVNGMLQCVAAGFPEPTIDWYFCPGTEQRCSVPVGPVDVQIQNSSVSPFGKLVVYSTID
DSTFKHNGTVECRAYNDVGKSSASFNFAFKGNNKEQIHAHTLFTPLLIGFVIAAGLMCIF
VMILTYKYLQKPMYEVQWKVVEEINGNNYVYIDPTQLPYDHKWEFPRNRLSFGKTLGAGA
FGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLSYLGNHMNIVNLLGA
CTIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEVALYKNLLHSKESSCNDSTN
EYMDMKPGVSYVVPTKAADKRRSARIGSYIERDVTPAIMEDDELALDLEDLLSFSYQVAK
GMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMAP
ESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAE
MYDIMKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLANCSPHRENPAVDHSVRIN
SVGSSASSTQPLLVHEDV
NT seq 2937 nt   +upstreamnt  +downstreamnt
atgagaggcgctcgcggcgcctgggatttcctcttcgttctgctgctcctgctcctcgtc
cagacaggctcttctcaaccatctgtgagtccaggagaactgtctctaccatctatccat
ccagcaaaatcagagttaattgtcagtgttggcgacgagattaggctgttatgcactgat
ccaggatttgtcaagtggacttttgagatcctgggtcaactgagtgagaagacaaatccg
gaatggatcaccgagaaagcagaggccacaaatacaggcaattacacgtgcaccaataaa
ggcggcttgagcagttccatttatgtgtttgttagagaccctgagaagcttttcctgatt
gaccttcccttgtacgggaaagaagaaaacgacacgctggttcgctgtcccctgacagac
cccgaggtgaccaattactctctcacggggtgtgaggggaaacctctccccaaggatttg
acgtttgtggctgaccccaaggcaggcatcacaatcagaaatgtgaagcgcgagtaccat
cggctctgtctgcactgctcagcgaatcagaagggcaagtccatgctgtcaaagaaattc
accctgaaagtgcgggcagccatcaaagctgtgccggttgtgtctgtgtccaaaaccagc
tatcttctcagggaaggagaggaatttgcagtgacgtgcttgattaaagacgtgtctagt
tccgtggactctatgtggataaaggaaaacagccagcagagtaaagcacagacgaagaag
aatagctggcatcagggtgacttcagttatctccgtcaggaaaggctgactatcagctca
gcaagagtgaatgattccggtgtgttcatgtgttacgccaataatacttttggatcagca
aatgtcacaacaaccttagaagtagtagataaaggattcattaatatcttccctatgatg
aacacaacagtgtttgtaaatgatggagagaatgtggatctggttgttgagtatgaggca
tatcccaaacctgaacaccgacagtggatatatatgaacagaacctccactgataagtgg
gacgattatcccaagtctgagaatgaaagtaacatcagatacgtaaatgaacttcatcta
accagattaaaagggactgaaggaggcacttacacatttcacgtgtccaattctgatgtc
aattcttccgtgacatttaatgttaacgtgaacacaaaaccagaaatcctgacacatgac
aggctggtgaatggcatgctacagtgcgtggctgcagggttcccggagccaaccatcgat
tggtacttttgtccaggaaccgagcagaggtgttctgttcctgttgggccagtggatgta
cagatccaaaactcatctgtctcaccatttggaaaactagtggtttatagcaccattgat
gacagcacattcaaacacaatgggacggtggaatgcagggcttacaacgatgtgggcaag
agttctgcctcttttaactttgcatttaaaggtaacaacaaagaacaaatccatgctcac
accctgttcacgccgttgctgattggttttgtgatcgcagctggtttaatgtgtatcttc
gtgatgattcttacatacaaatatttgcagaaacccatgtatgaagtacagtggaaagtt
gtcgaggagataaatgggaacaattatgtttacatagacccaacacaacttccttatgat
cacaaatgggagtttcccaggaacaggctgagttttgggaaaaccttgggtgctggcgcc
tttgggaaagtcgttgaggccaccgcttatggcttaattaaatcggatgcagccatgact
gttgctgtcaagatgctcaaaccaagcgcccatttaacagaacgagaagccctaatgtct
gaactcaaagtcttgagttacctcggtaatcatatgaatattgtgaatcttctgggagcg
tgcaccattggagggcccaccctggtcattacagaatattgttgctatggtgatcttctg
aattttttgagaagaaaacgtgattcatttatttgctcaaagcaggaagatcatgccgaa
gtggcactttataagaaccttcttcattcaaaggagtcttcctgcaatgatagtactaat
gagtacatggacatgaaacctggagtttcttatgttgtaccaaccaaggcggcagacaag
aggagatctgcaagaataggttcatacatagaaagagacgtgactcctgctatcatggaa
gatgatgagctggccctggacctggaggacttgctgagcttttcttaccaggtggcaaag
ggcatggcgttccttgcctcaaagaattgtattcatagagacttggcagccagaaatatc
ctccttactcatggtcgaatcacaaagatttgtgattttggtctagccagagacatcaag
aatgattctaattatgtggtcaaaggaaacgctcgactccctgtgaagtggatggcaccg
gagagtattttcaactgtgtgtacacatttgaaagtgatgtctggtcctatgggattttt
ctgtgggagctgttctctttaggaagcagcccctaccctggaatgccagtcgattctaag
ttctacaagatgatcaaggaaggtttccgaatgctcagccccgagcatgcacctgcggaa
atgtatgacatcatgaagacctgctgggatgcagatcccttgaaaaggccaacatttaag
cagattgtgcagctgattgagaagcagatctcagagagcaccaatcatatttattccaac
ttagcaaactgcagcccccaccgggagaaccccgcggtggaccattctgtgcgcatcaac
tctgtgggcagcagcgcctcctccacgcagcctctgcttgtccacgaagatgtctga

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