Callithrix jacchus (white-tufted-ear marmoset): 100387961
Help
Entry
100387961 CDS
T03264
Gene name
ARAF, SYN1
Definition
(RefSeq) A-Raf proto-oncogene, serine/threonine kinase
KO
K08845
A-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
cjc
Callithrix jacchus (white-tufted-ear marmoset)
Pathway
cjc01521
EGFR tyrosine kinase inhibitor resistance
cjc01522
Endocrine resistance
cjc04010
MAPK signaling pathway
cjc04012
ErbB signaling pathway
cjc04068
FoxO signaling pathway
cjc04270
Vascular smooth muscle contraction
cjc04650
Natural killer cell mediated cytotoxicity
cjc04720
Long-term potentiation
cjc04726
Serotonergic synapse
cjc04730
Long-term depression
cjc04810
Regulation of actin cytoskeleton
cjc04910
Insulin signaling pathway
cjc04914
Progesterone-mediated oocyte maturation
cjc04928
Parathyroid hormone synthesis, secretion and action
cjc05010
Alzheimer disease
cjc05022
Pathways of neurodegeneration - multiple diseases
cjc05034
Alcoholism
cjc05160
Hepatitis C
cjc05161
Hepatitis B
cjc05200
Pathways in cancer
cjc05205
Proteoglycans in cancer
cjc05210
Colorectal cancer
cjc05211
Renal cell carcinoma
cjc05212
Pancreatic cancer
cjc05213
Endometrial cancer
cjc05214
Glioma
cjc05215
Prostate cancer
cjc05218
Melanoma
cjc05219
Bladder cancer
cjc05220
Chronic myeloid leukemia
cjc05221
Acute myeloid leukemia
cjc05223
Non-small cell lung cancer
cjc05224
Breast cancer
cjc05225
Hepatocellular carcinoma
cjc05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
cjc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100387961 (ARAF)
04012 ErbB signaling pathway
100387961 (ARAF)
04068 FoxO signaling pathway
100387961 (ARAF)
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
100387961 (ARAF)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100387961 (ARAF)
09152 Endocrine system
04910 Insulin signaling pathway
100387961 (ARAF)
04914 Progesterone-mediated oocyte maturation
100387961 (ARAF)
04928 Parathyroid hormone synthesis, secretion and action
100387961 (ARAF)
09153 Circulatory system
04270 Vascular smooth muscle contraction
100387961 (ARAF)
09156 Nervous system
04726 Serotonergic synapse
100387961 (ARAF)
04720 Long-term potentiation
100387961 (ARAF)
04730 Long-term depression
100387961 (ARAF)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100387961 (ARAF)
05205 Proteoglycans in cancer
100387961 (ARAF)
09162 Cancer: specific types
05210 Colorectal cancer
100387961 (ARAF)
05212 Pancreatic cancer
100387961 (ARAF)
05225 Hepatocellular carcinoma
100387961 (ARAF)
05226 Gastric cancer
100387961 (ARAF)
05214 Glioma
100387961 (ARAF)
05221 Acute myeloid leukemia
100387961 (ARAF)
05220 Chronic myeloid leukemia
100387961 (ARAF)
05218 Melanoma
100387961 (ARAF)
05211 Renal cell carcinoma
100387961 (ARAF)
05219 Bladder cancer
100387961 (ARAF)
05215 Prostate cancer
100387961 (ARAF)
05213 Endometrial cancer
100387961 (ARAF)
05224 Breast cancer
100387961 (ARAF)
05223 Non-small cell lung cancer
100387961 (ARAF)
09164 Neurodegenerative disease
05010 Alzheimer disease
100387961 (ARAF)
05022 Pathways of neurodegeneration - multiple diseases
100387961 (ARAF)
09165 Substance dependence
05034 Alcoholism
100387961 (ARAF)
09172 Infectious disease: viral
05161 Hepatitis B
100387961 (ARAF)
05160 Hepatitis C
100387961 (ARAF)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100387961 (ARAF)
01522 Endocrine resistance
100387961 (ARAF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cjc01001
]
100387961 (ARAF)
Enzymes [BR:
cjc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100387961 (ARAF)
Protein kinases [BR:
cjc01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
100387961 (ARAF)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
Pkinase_fungal
APH
TUG-UBL1
zf-RING-like
Kdo
Motif
Other DBs
NCBI-GeneID:
100387961
NCBI-ProteinID:
XP_008987456
Ensembl:
ENSCJAG00000012431
UniProt:
A0A5K1VS71
LinkDB
All DBs
Position
X
AA seq
611 aa
AA seq
DB search
MEPPRGPPANGAEPCRAVGTVKVYLPNKQRTVVTVRDGMSVYDSLDKALKVRGLNQDCCV
VYRLIKGRKTVTAWDTAIAPLDGEELIVEVLEDVPLTMHNFVRKTFFSLAFCDFCLKFLF
HGFRCQTCGYKFHQHCSSKVPTVCVDMSTTCQQFYHSVQDLSRGSKQHEAPSNRPLNESL
TPQGPSLSPGSPCNQHCDPEHFPFPTPANAPLQRIRSTSTPNVHMVSSTAPMDSNLIQLT
GQSFSTDAASSRGGGDGAPRGSPSPVSVSSGRKSPHSKSPAEQRERKSLADDKKKVKNLG
YRDSGYYWEVPPSEVQLLKRIGTGSFGTVFRGRWHGDVAVKVLKVSQPTAEQAQAFKNEM
QVLRKTRHVNILLFMGFMTRPGFAIITQWCEGSSLYHHLHVADTRFDMVQLIDVARQTAQ
GMDYLHAKNIIHRDLKSNNIFLHEGLTVKIGDFGLATVKTRWSGAQPLEQPSGSVLWMAA
EVIRMQDPNPYSFQSDVYAYGVVLYELMTGSLPYSHIGCRDQIIFMVGRGYLSPDLSKIS
SNCPKAMRRLLSDCLKFQREERPLFPQILATIELLQRSLPKIERSASEPSLHRTQADELP
ACLLSAARLVP
NT seq
1836 nt
NT seq
+upstream
nt +downstream
nt
atggagccaccacggggcccccctgccaatggggccgagccgtgccgggcagtgggcacc
gtcaaagtgtacctgcccaacaagcaacgcacagtggtaactgtccgggatggcatgagt
gtctacgactctctagacaaggccctgaaggtgcggggtctaaatcaggactgctgtgtg
gtctaccgactcatcaagggacgaaagacggttactgcctgggacacagccatcgctccc
ctggatggcgaggagctcattgtcgaggtccttgaagatgttccgctgaccatgcacaat
tttgtacggaagaccttcttcagcctggcgttctgcgacttctgccttaagtttctgttc
catggcttccgttgccaaacctgtggctacaagttccaccagcattgttcctccaaggtc
cccacagtctgtgttgacatgagtaccacctgccaacagttctaccacagtgtccaggat
ttgtccagaggctccaaacagcatgaggctccctcaaaccgccccctgaatgagtcgcta
accccccagggtcccagcctttcccctggcagcccctgcaaccagcactgtgacccggag
cacttccccttccccaccccagccaatgctcccctgcagcgcatccgctccacgtccact
cccaacgtccatatggtcagctccacggctcccatggactccaacctcatccagctcact
ggccagagtttcagcactgatgctgccagtagtagaggaggtggagatggagccccccgg
gggagccccagcccagtcagcgtgtcctcggggaggaagtccccacattccaagtcacca
gcagagcagcgtgagcggaagtccttggctgatgacaagaaaaaagtgaagaacctgggg
taccgggactcaggctattactgggaggtaccacccagtgaggtgcagctgctgaagagg
attgggacaggctcgtttggcaccgtgtttcgagggcggtggcatggcgatgtggctgtg
aaggtgctcaaggtgtcccagcccacagctgagcaggcccaagccttcaagaacgagatg
caggtgctcaggaagacgcgacatgtcaacatcttgctgtttatgggcttcatgacccgg
ccgggatttgccatcatcacacagtggtgtgagggctccagcctctaccaccacctgcat
gtggccgacacacgcttcgacatggtccagctcatcgatgtggcccggcagactgcccag
ggcatggactacctccatgccaagaacatcatccaccgagatctcaagtctaacaacatc
ttcctacacgaggggctcacagtgaagattggtgactttggcttggccacggtgaagact
cgatggagcggggcccagcccttggagcagccctcaggctctgtgctgtggatggcagct
gaggtgatccgtatgcaggacccgaacccctacagcttccagtcagatgtctatgcctat
ggggttgtgctctacgagctcatgactggctcactgccttacagccacattggctgccgt
gaccagattatctttatggtgggccgtggctatctgtccccggacctcagcaaaatctcc
agcaactgccccaaggccatgcggcgcctgctgtctgactgcctcaagttccagcgggag
gagcggcccctcttcccccagattttggccacaattgagctgctgcaacggtcactcccc
aagattgagcggagtgcctcggaaccctccttgcaccgcacccaggctgatgagttgcct
gcctgcctactcagcgcagcccgccttgtgccttag
Callithrix jacchus (white-tufted-ear marmoset): 100403091
Help
Entry
100403091 CDS
T03264
Gene name
BRAF
Definition
(RefSeq) B-Raf proto-oncogene, serine/threonine kinase
KO
K04365
B-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
cjc
Callithrix jacchus (white-tufted-ear marmoset)
Pathway
cjc01521
EGFR tyrosine kinase inhibitor resistance
cjc01522
Endocrine resistance
cjc04010
MAPK signaling pathway
cjc04012
ErbB signaling pathway
cjc04015
Rap1 signaling pathway
cjc04024
cAMP signaling pathway
cjc04062
Chemokine signaling pathway
cjc04068
FoxO signaling pathway
cjc04150
mTOR signaling pathway
cjc04270
Vascular smooth muscle contraction
cjc04510
Focal adhesion
cjc04650
Natural killer cell mediated cytotoxicity
cjc04720
Long-term potentiation
cjc04722
Neurotrophin signaling pathway
cjc04726
Serotonergic synapse
cjc04730
Long-term depression
cjc04810
Regulation of actin cytoskeleton
cjc04910
Insulin signaling pathway
cjc04914
Progesterone-mediated oocyte maturation
cjc04928
Parathyroid hormone synthesis, secretion and action
cjc04934
Cushing syndrome
cjc05010
Alzheimer disease
cjc05022
Pathways of neurodegeneration - multiple diseases
cjc05034
Alcoholism
cjc05160
Hepatitis C
cjc05161
Hepatitis B
cjc05200
Pathways in cancer
cjc05205
Proteoglycans in cancer
cjc05210
Colorectal cancer
cjc05211
Renal cell carcinoma
cjc05212
Pancreatic cancer
cjc05213
Endometrial cancer
cjc05214
Glioma
cjc05215
Prostate cancer
cjc05216
Thyroid cancer
cjc05218
Melanoma
cjc05219
Bladder cancer
cjc05220
Chronic myeloid leukemia
cjc05221
Acute myeloid leukemia
cjc05223
Non-small cell lung cancer
cjc05224
Breast cancer
cjc05225
Hepatocellular carcinoma
cjc05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
cjc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100403091 (BRAF)
04012 ErbB signaling pathway
100403091 (BRAF)
04015 Rap1 signaling pathway
100403091 (BRAF)
04068 FoxO signaling pathway
100403091 (BRAF)
04024 cAMP signaling pathway
100403091 (BRAF)
04150 mTOR signaling pathway
100403091 (BRAF)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100403091 (BRAF)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100403091 (BRAF)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100403091 (BRAF)
04062 Chemokine signaling pathway
100403091 (BRAF)
09152 Endocrine system
04910 Insulin signaling pathway
100403091 (BRAF)
04914 Progesterone-mediated oocyte maturation
100403091 (BRAF)
04928 Parathyroid hormone synthesis, secretion and action
100403091 (BRAF)
09153 Circulatory system
04270 Vascular smooth muscle contraction
100403091 (BRAF)
09156 Nervous system
04726 Serotonergic synapse
100403091 (BRAF)
04720 Long-term potentiation
100403091 (BRAF)
04730 Long-term depression
100403091 (BRAF)
04722 Neurotrophin signaling pathway
100403091 (BRAF)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100403091 (BRAF)
05205 Proteoglycans in cancer
100403091 (BRAF)
09162 Cancer: specific types
05210 Colorectal cancer
100403091 (BRAF)
05212 Pancreatic cancer
100403091 (BRAF)
05225 Hepatocellular carcinoma
100403091 (BRAF)
05226 Gastric cancer
100403091 (BRAF)
05214 Glioma
100403091 (BRAF)
05216 Thyroid cancer
100403091 (BRAF)
05221 Acute myeloid leukemia
100403091 (BRAF)
05220 Chronic myeloid leukemia
100403091 (BRAF)
05218 Melanoma
100403091 (BRAF)
05211 Renal cell carcinoma
100403091 (BRAF)
05219 Bladder cancer
100403091 (BRAF)
05215 Prostate cancer
100403091 (BRAF)
05213 Endometrial cancer
100403091 (BRAF)
05224 Breast cancer
100403091 (BRAF)
05223 Non-small cell lung cancer
100403091 (BRAF)
09164 Neurodegenerative disease
05010 Alzheimer disease
100403091 (BRAF)
05022 Pathways of neurodegeneration - multiple diseases
100403091 (BRAF)
09165 Substance dependence
05034 Alcoholism
100403091 (BRAF)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100403091 (BRAF)
09172 Infectious disease: viral
05161 Hepatitis B
100403091 (BRAF)
05160 Hepatitis C
100403091 (BRAF)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100403091 (BRAF)
01522 Endocrine resistance
100403091 (BRAF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cjc01001
]
100403091 (BRAF)
Enzymes [BR:
cjc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100403091 (BRAF)
Protein kinases [BR:
cjc01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
100403091 (BRAF)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
C1_2
Pkinase_fungal
APH
Kdo
Motif
Other DBs
NCBI-GeneID:
100403091
NCBI-ProteinID:
XP_002751976
Ensembl:
ENSCJAG00000013536
UniProt:
U3CMC6
LinkDB
All DBs
Position
8
AA seq
764 aa
AA seq
DB search
MAALSGGGGGSAEPGQALFNGDMEPEAGAGAATSSAADPAIPEEVWNIKQMIKLTQEHIE
ALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASMDTVTS
SSSSSLSVLPSSLSVFQNPADVSRSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLK
KALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTF
FTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQ
EEPSLAETALTSGSSPSAPPSDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDR
SSSAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGP
QRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAV
KMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLH
IIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKS
RWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNR
DQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLP
KIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGAFPVH
NT seq
2295 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgctgagcggtggcggtggcggcagcgcggagccgggccaggctctgttcaac
ggggacatggagcctgaggccggcgccggcgctgcgacctcttccgctgcggaccctgcc
attcctgaggaggtgtggaatatcaaacaaatgattaagttgacacaggaacatatagag
gcccttttggacaaatttggtggggagcataatccaccatcaatatatctggaggcatat
gaagaatacaccagcaagctagatgcactccaacaaagagaacaacagttattggaatct
ctggggaacggaactgatttttctgtttctagctctgcatcaatggacaccgttacatct
tcctcctcttcgagcctttcagtgctaccttcatctctttcagtttttcaaaatcccgca
gatgtgtcacggagcaaccccaagtcaccacaaaaacctatcgttagagtcttcctgccc
aacaaacagaggacagtggtacctgcaaggtgtggagttacagtccgagacagtctaaag
aaagcactgatgatgagaggtctaatcccagagtgctgtgctgtttacagaattcaggat
ggagagaagaaaccaattggctgggacactgatatctcctggcttactggagaagaattg
catgtggaagtgttggagaatgttccacttacaacacacaactttgtacgaaaaacattt
ttcaccttagcattttgtgacttttgtcgaaagctgcttttccagggtttccgctgtcaa
acgtgtggttataaatttcaccagcgttgtagtacagaggttccactgatgtgtgttaat
tatgaccaacttgatttgctgtttgtctccaagttctttgaacaccacccaataccacag
gaagagccttccttagcagagactgctcttacatctggatcatccccttccgcacccccc
tcagactctattgggccccaaattctcaccagtccatctccttcaaaatccattccaatt
ccacagcccttccgaccagcagatgaagatcatcgaaatcaatttgggcaacgagaccgg
tcctcatcagctcccaatgtgcatataaacacaatagaacctgttaatattgatgacttg
attagagaccaaggatttcgtggtgatggaggatcaaccacaggtttgtctgccacaccc
cctgcctcattacctggctcactcactaacgtgaaagccttacagaaatctccaggacct
cagagagaaaggaagtcatcttcatcctcagaagacaggaatcgaatgaaaacacttggt
agaagggactcgagtgatgattgggagattcctgatggacagattacagtgggacaaaga
attggatctggatcatttggaacagtttacaagggaaagtggcatggtgacgtggcagtg
aaaatgttgaatgtgacagcacctacacctcagcaattacaagccttcaaaaatgaagta
ggagtactcaggaaaacacgacacgtgaatatcctactcttcatgggctattccacaaag
ccacaactggctattgttacccagtggtgtgagggctccagcttgtatcaccatctccat
atcattgagaccaaatttgagatgatcaaacttatagatattgcacgacagactgcacag
ggcatggattacttacacgccaagtcaatcatccacagagacctcaagagtaataatata
tttcttcatgaagacctcacagtaaaaataggtgattttggtctagccacagtgaaatct
cgatggagtgggtcccatcagtttgaacagttgtctggatccattttgtggatggcacca
gaagtcatcagaatgcaagataaaaatccatatagctttcagtcagatgtatatgcattt
gggattgttctgtatgaattgatgactggacagttaccttattcaaacatcaacaacagg
gaccagataatttttatggtgggacgaggatacctatctccagatctcagtaaggtacgg
agtaactgtccaaaagccatgaagagattaatggcagagtgcctcaaaaagaaaagagat
gagagaccactgtttccacaaattctcgcctctattgagctgctggcccgctcattgcca
aaaattcaccgcagtgcatcagaaccctccttgaatcgggctggtttccaaacagaggat
tttagtctatatgcttgtgcttctccaaaaacacccatccaggcagggggatatggtgcg
tttcctgtccactga
Callithrix jacchus (white-tufted-ear marmoset): 100415300
Help
Entry
100415300 CDS
T03264
Gene name
RAF1
Definition
(RefSeq) Raf-1 proto-oncogene, serine/threonine kinase
KO
K04366
RAF proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
cjc
Callithrix jacchus (white-tufted-ear marmoset)
Pathway
cjc01521
EGFR tyrosine kinase inhibitor resistance
cjc01522
Endocrine resistance
cjc04010
MAPK signaling pathway
cjc04012
ErbB signaling pathway
cjc04014
Ras signaling pathway
cjc04015
Rap1 signaling pathway
cjc04022
cGMP-PKG signaling pathway
cjc04024
cAMP signaling pathway
cjc04062
Chemokine signaling pathway
cjc04068
FoxO signaling pathway
cjc04071
Sphingolipid signaling pathway
cjc04072
Phospholipase D signaling pathway
cjc04140
Autophagy - animal
cjc04150
mTOR signaling pathway
cjc04151
PI3K-Akt signaling pathway
cjc04210
Apoptosis
cjc04218
Cellular senescence
cjc04270
Vascular smooth muscle contraction
cjc04360
Axon guidance
cjc04370
VEGF signaling pathway
cjc04371
Apelin signaling pathway
cjc04510
Focal adhesion
cjc04540
Gap junction
cjc04550
Signaling pathways regulating pluripotency of stem cells
cjc04613
Neutrophil extracellular trap formation
cjc04625
C-type lectin receptor signaling pathway
cjc04630
JAK-STAT signaling pathway
cjc04650
Natural killer cell mediated cytotoxicity
cjc04660
T cell receptor signaling pathway
cjc04662
B cell receptor signaling pathway
cjc04664
Fc epsilon RI signaling pathway
cjc04666
Fc gamma R-mediated phagocytosis
cjc04720
Long-term potentiation
cjc04722
Neurotrophin signaling pathway
cjc04726
Serotonergic synapse
cjc04730
Long-term depression
cjc04810
Regulation of actin cytoskeleton
cjc04910
Insulin signaling pathway
cjc04912
GnRH signaling pathway
cjc04914
Progesterone-mediated oocyte maturation
cjc04915
Estrogen signaling pathway
cjc04916
Melanogenesis
cjc04917
Prolactin signaling pathway
cjc04919
Thyroid hormone signaling pathway
cjc04921
Oxytocin signaling pathway
cjc04926
Relaxin signaling pathway
cjc04928
Parathyroid hormone synthesis, secretion and action
cjc04929
GnRH secretion
cjc04935
Growth hormone synthesis, secretion and action
cjc05010
Alzheimer disease
cjc05022
Pathways of neurodegeneration - multiple diseases
cjc05034
Alcoholism
cjc05132
Salmonella infection
cjc05152
Tuberculosis
cjc05160
Hepatitis C
cjc05161
Hepatitis B
cjc05163
Human cytomegalovirus infection
cjc05164
Influenza A
cjc05165
Human papillomavirus infection
cjc05167
Kaposi sarcoma-associated herpesvirus infection
cjc05170
Human immunodeficiency virus 1 infection
cjc05200
Pathways in cancer
cjc05205
Proteoglycans in cancer
cjc05206
MicroRNAs in cancer
cjc05210
Colorectal cancer
cjc05211
Renal cell carcinoma
cjc05212
Pancreatic cancer
cjc05213
Endometrial cancer
cjc05214
Glioma
cjc05215
Prostate cancer
cjc05218
Melanoma
cjc05219
Bladder cancer
cjc05220
Chronic myeloid leukemia
cjc05221
Acute myeloid leukemia
cjc05223
Non-small cell lung cancer
cjc05224
Breast cancer
cjc05225
Hepatocellular carcinoma
cjc05226
Gastric cancer
cjc05230
Central carbon metabolism in cancer
cjc05231
Choline metabolism in cancer
cjc05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
cjc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100415300 (RAF1)
04012 ErbB signaling pathway
100415300 (RAF1)
04014 Ras signaling pathway
100415300 (RAF1)
04015 Rap1 signaling pathway
100415300 (RAF1)
04370 VEGF signaling pathway
100415300 (RAF1)
04371 Apelin signaling pathway
100415300 (RAF1)
04630 JAK-STAT signaling pathway
100415300 (RAF1)
04068 FoxO signaling pathway
100415300 (RAF1)
04072 Phospholipase D signaling pathway
100415300 (RAF1)
04071 Sphingolipid signaling pathway
100415300 (RAF1)
04024 cAMP signaling pathway
100415300 (RAF1)
04022 cGMP-PKG signaling pathway
100415300 (RAF1)
04151 PI3K-Akt signaling pathway
100415300 (RAF1)
04150 mTOR signaling pathway
100415300 (RAF1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100415300 (RAF1)
09143 Cell growth and death
04210 Apoptosis
100415300 (RAF1)
04218 Cellular senescence
100415300 (RAF1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
100415300 (RAF1)
04540 Gap junction
100415300 (RAF1)
04550 Signaling pathways regulating pluripotency of stem cells
100415300 (RAF1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100415300 (RAF1)
09150 Organismal Systems
09151 Immune system
04613 Neutrophil extracellular trap formation
100415300 (RAF1)
04625 C-type lectin receptor signaling pathway
100415300 (RAF1)
04650 Natural killer cell mediated cytotoxicity
100415300 (RAF1)
04660 T cell receptor signaling pathway
100415300 (RAF1)
04662 B cell receptor signaling pathway
100415300 (RAF1)
04664 Fc epsilon RI signaling pathway
100415300 (RAF1)
04666 Fc gamma R-mediated phagocytosis
100415300 (RAF1)
04062 Chemokine signaling pathway
100415300 (RAF1)
09152 Endocrine system
04910 Insulin signaling pathway
100415300 (RAF1)
04929 GnRH secretion
100415300 (RAF1)
04912 GnRH signaling pathway
100415300 (RAF1)
04915 Estrogen signaling pathway
100415300 (RAF1)
04914 Progesterone-mediated oocyte maturation
100415300 (RAF1)
04917 Prolactin signaling pathway
100415300 (RAF1)
04921 Oxytocin signaling pathway
100415300 (RAF1)
04926 Relaxin signaling pathway
100415300 (RAF1)
04935 Growth hormone synthesis, secretion and action
100415300 (RAF1)
04919 Thyroid hormone signaling pathway
100415300 (RAF1)
04928 Parathyroid hormone synthesis, secretion and action
100415300 (RAF1)
04916 Melanogenesis
100415300 (RAF1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
100415300 (RAF1)
09156 Nervous system
04726 Serotonergic synapse
100415300 (RAF1)
04720 Long-term potentiation
100415300 (RAF1)
04730 Long-term depression
100415300 (RAF1)
04722 Neurotrophin signaling pathway
100415300 (RAF1)
09158 Development and regeneration
04360 Axon guidance
100415300 (RAF1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100415300 (RAF1)
05206 MicroRNAs in cancer
100415300 (RAF1)
05205 Proteoglycans in cancer
100415300 (RAF1)
05230 Central carbon metabolism in cancer
100415300 (RAF1)
05231 Choline metabolism in cancer
100415300 (RAF1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100415300 (RAF1)
09162 Cancer: specific types
05210 Colorectal cancer
100415300 (RAF1)
05212 Pancreatic cancer
100415300 (RAF1)
05225 Hepatocellular carcinoma
100415300 (RAF1)
05226 Gastric cancer
100415300 (RAF1)
05214 Glioma
100415300 (RAF1)
05221 Acute myeloid leukemia
100415300 (RAF1)
05220 Chronic myeloid leukemia
100415300 (RAF1)
05218 Melanoma
100415300 (RAF1)
05211 Renal cell carcinoma
100415300 (RAF1)
05219 Bladder cancer
100415300 (RAF1)
05215 Prostate cancer
100415300 (RAF1)
05213 Endometrial cancer
100415300 (RAF1)
05224 Breast cancer
100415300 (RAF1)
05223 Non-small cell lung cancer
100415300 (RAF1)
09164 Neurodegenerative disease
05010 Alzheimer disease
100415300 (RAF1)
05022 Pathways of neurodegeneration - multiple diseases
100415300 (RAF1)
09165 Substance dependence
05034 Alcoholism
100415300 (RAF1)
09171 Infectious disease: bacterial
05132 Salmonella infection
100415300 (RAF1)
05152 Tuberculosis
100415300 (RAF1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
100415300 (RAF1)
05161 Hepatitis B
100415300 (RAF1)
05160 Hepatitis C
100415300 (RAF1)
05164 Influenza A
100415300 (RAF1)
05163 Human cytomegalovirus infection
100415300 (RAF1)
05167 Kaposi sarcoma-associated herpesvirus infection
100415300 (RAF1)
05165 Human papillomavirus infection
100415300 (RAF1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100415300 (RAF1)
01522 Endocrine resistance
100415300 (RAF1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cjc01001
]
100415300 (RAF1)
Enzymes [BR:
cjc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100415300 (RAF1)
Protein kinases [BR:
cjc01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
100415300 (RAF1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
Pkinase_fungal
C1_2
Motif
Other DBs
NCBI-GeneID:
100415300
NCBI-ProteinID:
XP_017820594
Ensembl:
ENSCJAG00000016737
UniProt:
F7CJL2
LinkDB
All DBs
Position
15
AA seq
668 aa
AA seq
DB search
MEHIQGAWKTISNGFGLKDAVFDGSSCISPTIVQQFGYQRRASDDGKLTDPSKTSNTIRV
FLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLLQEHKGKKARLDWNTDAAS
LIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLLNGFRCQTCGYKFHEHCSTKV
PTMCVDWSNIRQLLLFPNSTVGDSGVPALPSLTMRRMRESVTRMPVSSQHRYSTPHAFTF
NTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRMIENNNLNASPRAWSRRFCLRGRDA
IRSHSESASPSALSSSPNNLSPTGWSQPKAPMPAQRERAPGSGTQEKNKIRPRGQRDSSY
YWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRNEVAVLRKT
RHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIARQTAQGMDYLH
AKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGSVLWMAPEVIRMQ
DNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYASPDLSKLYKNCPKA
MKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPSLHRAAHTEDINACTLT
TSPRLPVF
NT seq
2007 nt
NT seq
+upstream
nt +downstream
nt
atggagcacatacagggagcttggaagacgatcagcaatggttttggactcaaagatgct
gtgtttgatggctccagctgcatctctcctacaatagttcagcagtttggttatcagcgc
cgggcatcagatgatggcaaactcacagatccttcgaagacaagcaacactatccgtgtt
ttcttgccgaacaagcaacgaacagtggtcaatgtgcgaaatggaatgagcttgcatgac
tgccttatgaaagcgctcaaggtgaggggcctgcaaccagaatgctgtgcagtgttcaga
cttctccaagaacataaaggtaaaaaagcacgcttagattggaatactgatgctgcctct
ttgattggagaagaacttcaagtagatttcctggatcatgttcccctcacaacacacaac
tttgctcggaagacgttcctgaagcttgccttctgtgacatctgtcagaaattcctgctc
aatggatttcgatgtcagacttgtggctacaaatttcatgagcactgtagcaccaaagta
cctactatgtgtgtggactggagtaatatcagacaactcttattgtttccaaattccact
gttggtgatagtggagtcccagcactaccttctttgactatgcgtcgtatgcgagagtct
gttacccggatgcctgttagttctcagcacagatattctacacctcatgccttcaccttt
aacacctccagtccctcatctgaaggttccctctcccagaggcagaggtcaacgtccaca
cctaatgtccacatggtcagcaccaccctgcctgtggatagcaggatgattgagaataac
aacctgaatgcttctcccagggcgtggtccagacgattttgtttgaggggaagagatgca
attcgaagtcacagcgaatcagcctcaccttcagccctgtccagtagccccaacaatctg
agcccaacaggctggtcacagcccaaagcccccatgccagcacaaagggagcgggcacca
ggatctggaacccaggagaaaaacaaaattaggcctcgtggacagagagattcaagctat
tactgggaaatagaagccagtgaagtgatgctctccactcggattgggtcaggctctttt
ggaactgtttataagggcaaatggcacggagatgttgcagtaaagatcctaaaggttgta
gacccaaccccagagcagttccaggccttcaggaatgaggtggctgttttgcgcaaaaca
cggcatgtgaacattctgcttttcatggggtacatgacaaaagacaacctggcaattgtg
acccagtggtgtgagggcagcagcctctacaaacacctgcatgtccaggagaccaagttt
cagatgttccagctaattgacattgcccggcagacggctcagggaatggactatttgcat
gcaaagaacatcatccacagagacatgaaatccaacaatatatttctccatgaaggccta
acagtgaaaattggagattttggtttggcaacagtaaagtcacgctggagtggttctcag
caggttgaacaacctactggctctgttctgtggatggctccagaggtgatccgaatgcag
gataacaaccccttcagcttccagtcagatgtctactcctatggcatcgtattatatgag
ctgatgacaggggagcttccttactctcacattaacaaccgagatcagatcatcttcatg
gtgggccgagggtatgcctccccagatcttagtaagctatataaaaactgccccaaagca
atgaagaggctggtagctgactgtgtcaagaaagtaaaggaagagaggcctctttttccc
cagatcctgtcttccattgagctgctccagcactctctaccgaagatcaaccggagcgct
tccgagccatccttgcatcgggcagcccacactgaggatatcaatgcttgcacgctgacc
acgtccccaaggctgcctgtcttctag
DBGET
integrated database retrieval system
