Callithrix jacchus (white-tufted-ear marmoset): 100403091
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Entry
100403091 CDS
T03264
Gene name
BRAF
Definition
(RefSeq) B-Raf proto-oncogene, serine/threonine kinase
KO
K04365
B-Raf proto-oncogene serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
cjc
Callithrix jacchus (white-tufted-ear marmoset)
Pathway
cjc01521
EGFR tyrosine kinase inhibitor resistance
cjc01522
Endocrine resistance
cjc04010
MAPK signaling pathway
cjc04012
ErbB signaling pathway
cjc04015
Rap1 signaling pathway
cjc04024
cAMP signaling pathway
cjc04062
Chemokine signaling pathway
cjc04068
FoxO signaling pathway
cjc04150
mTOR signaling pathway
cjc04270
Vascular smooth muscle contraction
cjc04510
Focal adhesion
cjc04650
Natural killer cell mediated cytotoxicity
cjc04720
Long-term potentiation
cjc04722
Neurotrophin signaling pathway
cjc04726
Serotonergic synapse
cjc04730
Long-term depression
cjc04810
Regulation of actin cytoskeleton
cjc04910
Insulin signaling pathway
cjc04914
Progesterone-mediated oocyte maturation
cjc04928
Parathyroid hormone synthesis, secretion and action
cjc04934
Cushing syndrome
cjc05010
Alzheimer disease
cjc05022
Pathways of neurodegeneration - multiple diseases
cjc05034
Alcoholism
cjc05160
Hepatitis C
cjc05161
Hepatitis B
cjc05200
Pathways in cancer
cjc05205
Proteoglycans in cancer
cjc05210
Colorectal cancer
cjc05211
Renal cell carcinoma
cjc05212
Pancreatic cancer
cjc05213
Endometrial cancer
cjc05214
Glioma
cjc05215
Prostate cancer
cjc05216
Thyroid cancer
cjc05218
Melanoma
cjc05219
Bladder cancer
cjc05220
Chronic myeloid leukemia
cjc05221
Acute myeloid leukemia
cjc05223
Non-small cell lung cancer
cjc05224
Breast cancer
cjc05225
Hepatocellular carcinoma
cjc05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
cjc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100403091 (BRAF)
04012 ErbB signaling pathway
100403091 (BRAF)
04015 Rap1 signaling pathway
100403091 (BRAF)
04068 FoxO signaling pathway
100403091 (BRAF)
04024 cAMP signaling pathway
100403091 (BRAF)
04150 mTOR signaling pathway
100403091 (BRAF)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100403091 (BRAF)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100403091 (BRAF)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100403091 (BRAF)
04062 Chemokine signaling pathway
100403091 (BRAF)
09152 Endocrine system
04910 Insulin signaling pathway
100403091 (BRAF)
04914 Progesterone-mediated oocyte maturation
100403091 (BRAF)
04928 Parathyroid hormone synthesis, secretion and action
100403091 (BRAF)
09153 Circulatory system
04270 Vascular smooth muscle contraction
100403091 (BRAF)
09156 Nervous system
04726 Serotonergic synapse
100403091 (BRAF)
04720 Long-term potentiation
100403091 (BRAF)
04730 Long-term depression
100403091 (BRAF)
04722 Neurotrophin signaling pathway
100403091 (BRAF)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100403091 (BRAF)
05205 Proteoglycans in cancer
100403091 (BRAF)
09162 Cancer: specific types
05210 Colorectal cancer
100403091 (BRAF)
05212 Pancreatic cancer
100403091 (BRAF)
05225 Hepatocellular carcinoma
100403091 (BRAF)
05226 Gastric cancer
100403091 (BRAF)
05214 Glioma
100403091 (BRAF)
05216 Thyroid cancer
100403091 (BRAF)
05221 Acute myeloid leukemia
100403091 (BRAF)
05220 Chronic myeloid leukemia
100403091 (BRAF)
05218 Melanoma
100403091 (BRAF)
05211 Renal cell carcinoma
100403091 (BRAF)
05219 Bladder cancer
100403091 (BRAF)
05215 Prostate cancer
100403091 (BRAF)
05213 Endometrial cancer
100403091 (BRAF)
05224 Breast cancer
100403091 (BRAF)
05223 Non-small cell lung cancer
100403091 (BRAF)
09164 Neurodegenerative disease
05010 Alzheimer disease
100403091 (BRAF)
05022 Pathways of neurodegeneration - multiple diseases
100403091 (BRAF)
09165 Substance dependence
05034 Alcoholism
100403091 (BRAF)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100403091 (BRAF)
09172 Infectious disease: viral
05161 Hepatitis B
100403091 (BRAF)
05160 Hepatitis C
100403091 (BRAF)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100403091 (BRAF)
01522 Endocrine resistance
100403091 (BRAF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cjc01001
]
100403091 (BRAF)
Enzymes [BR:
cjc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100403091 (BRAF)
Protein kinases [BR:
cjc01001
]
Serine/threonine kinases: TKL group
RAF family [OT]
100403091 (BRAF)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
RBD
C1_1
Kinase-like
zf-RING-like
C1_2
Pkinase_fungal
APH
Kdo
Motif
Other DBs
NCBI-GeneID:
100403091
NCBI-ProteinID:
XP_002751976
Ensembl:
ENSCJAG00000013536
UniProt:
U3CMC6
LinkDB
All DBs
Position
8
AA seq
764 aa
AA seq
DB search
MAALSGGGGGSAEPGQALFNGDMEPEAGAGAATSSAADPAIPEEVWNIKQMIKLTQEHIE
ALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASMDTVTS
SSSSSLSVLPSSLSVFQNPADVSRSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLK
KALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTF
FTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQ
EEPSLAETALTSGSSPSAPPSDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDR
SSSAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGP
QRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAV
KMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLH
IIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKS
RWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNR
DQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLP
KIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGAFPVH
NT seq
2295 nt
NT seq
+upstream
nt +downstream
nt
atggcggcgctgagcggtggcggtggcggcagcgcggagccgggccaggctctgttcaac
ggggacatggagcctgaggccggcgccggcgctgcgacctcttccgctgcggaccctgcc
attcctgaggaggtgtggaatatcaaacaaatgattaagttgacacaggaacatatagag
gcccttttggacaaatttggtggggagcataatccaccatcaatatatctggaggcatat
gaagaatacaccagcaagctagatgcactccaacaaagagaacaacagttattggaatct
ctggggaacggaactgatttttctgtttctagctctgcatcaatggacaccgttacatct
tcctcctcttcgagcctttcagtgctaccttcatctctttcagtttttcaaaatcccgca
gatgtgtcacggagcaaccccaagtcaccacaaaaacctatcgttagagtcttcctgccc
aacaaacagaggacagtggtacctgcaaggtgtggagttacagtccgagacagtctaaag
aaagcactgatgatgagaggtctaatcccagagtgctgtgctgtttacagaattcaggat
ggagagaagaaaccaattggctgggacactgatatctcctggcttactggagaagaattg
catgtggaagtgttggagaatgttccacttacaacacacaactttgtacgaaaaacattt
ttcaccttagcattttgtgacttttgtcgaaagctgcttttccagggtttccgctgtcaa
acgtgtggttataaatttcaccagcgttgtagtacagaggttccactgatgtgtgttaat
tatgaccaacttgatttgctgtttgtctccaagttctttgaacaccacccaataccacag
gaagagccttccttagcagagactgctcttacatctggatcatccccttccgcacccccc
tcagactctattgggccccaaattctcaccagtccatctccttcaaaatccattccaatt
ccacagcccttccgaccagcagatgaagatcatcgaaatcaatttgggcaacgagaccgg
tcctcatcagctcccaatgtgcatataaacacaatagaacctgttaatattgatgacttg
attagagaccaaggatttcgtggtgatggaggatcaaccacaggtttgtctgccacaccc
cctgcctcattacctggctcactcactaacgtgaaagccttacagaaatctccaggacct
cagagagaaaggaagtcatcttcatcctcagaagacaggaatcgaatgaaaacacttggt
agaagggactcgagtgatgattgggagattcctgatggacagattacagtgggacaaaga
attggatctggatcatttggaacagtttacaagggaaagtggcatggtgacgtggcagtg
aaaatgttgaatgtgacagcacctacacctcagcaattacaagccttcaaaaatgaagta
ggagtactcaggaaaacacgacacgtgaatatcctactcttcatgggctattccacaaag
ccacaactggctattgttacccagtggtgtgagggctccagcttgtatcaccatctccat
atcattgagaccaaatttgagatgatcaaacttatagatattgcacgacagactgcacag
ggcatggattacttacacgccaagtcaatcatccacagagacctcaagagtaataatata
tttcttcatgaagacctcacagtaaaaataggtgattttggtctagccacagtgaaatct
cgatggagtgggtcccatcagtttgaacagttgtctggatccattttgtggatggcacca
gaagtcatcagaatgcaagataaaaatccatatagctttcagtcagatgtatatgcattt
gggattgttctgtatgaattgatgactggacagttaccttattcaaacatcaacaacagg
gaccagataatttttatggtgggacgaggatacctatctccagatctcagtaaggtacgg
agtaactgtccaaaagccatgaagagattaatggcagagtgcctcaaaaagaaaagagat
gagagaccactgtttccacaaattctcgcctctattgagctgctggcccgctcattgcca
aaaattcaccgcagtgcatcagaaccctccttgaatcgggctggtttccaaacagaggat
tttagtctatatgcttgtgcttctccaaaaacacccatccaggcagggggatatggtgcg
tttcctgtccactga
DBGET
integrated database retrieval system
