Delphinapterus leucas (beluga whale): 111183434
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Entry
111183434 CDS
T05885
Symbol
SIRT1
Name
(RefSeq) NAD-dependent protein deacetylase sirtuin-1 isoform X1
KO
K11411
NAD-dependent protein deacetylase sirtuin 1 [EC:
2.3.1.286
]
Organism
dle
Delphinapterus leucas (beluga whale)
Pathway
dle00760
Nicotinate and nicotinamide metabolism
dle01100
Metabolic pathways
dle04068
FoxO signaling pathway
dle04148
Efferocytosis
dle04152
AMPK signaling pathway
dle04211
Longevity regulating pathway
dle04213
Longevity regulating pathway - multiple species
dle04218
Cellular senescence
dle04310
Wnt signaling pathway
dle04922
Glucagon signaling pathway
dle04936
Alcoholic liver disease
dle05031
Amphetamine addiction
dle05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
dle00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00760 Nicotinate and nicotinamide metabolism
111183434 (SIRT1)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
111183434 (SIRT1)
04068 FoxO signaling pathway
111183434 (SIRT1)
04152 AMPK signaling pathway
111183434 (SIRT1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
111183434 (SIRT1)
09143 Cell growth and death
04218 Cellular senescence
111183434 (SIRT1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
111183434 (SIRT1)
09149 Aging
04211 Longevity regulating pathway
111183434 (SIRT1)
04213 Longevity regulating pathway - multiple species
111183434 (SIRT1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
111183434 (SIRT1)
09165 Substance dependence
05031 Amphetamine addiction
111183434 (SIRT1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
111183434 (SIRT1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
dle03036
]
111183434 (SIRT1)
03029 Mitochondrial biogenesis [BR:
dle03029
]
111183434 (SIRT1)
Enzymes [BR:
dle01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.286 protein acetyllysine N-acetyltransferase
111183434 (SIRT1)
Chromosome and associated proteins [BR:
dle03036
]
Eukaryotic type
Histone modification proteins
HDACs (histone deacetylases)
SIRTs (sirtuins, class III HDACs)
111183434 (SIRT1)
Mitochondrial biogenesis [BR:
dle03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
111183434 (SIRT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SIR2
DUF592
Motif
Other DBs
NCBI-GeneID:
111183434
NCBI-ProteinID:
XP_022446410
UniProt:
A0A2Y9PKW1
LinkDB
All DBs
Position
Unknown
AA seq
735 aa
AA seq
DB search
MADEAALAFQPGGSPSAVTAEREAPSPPAGEPLRKRPRRDGPGVGRSPGEPGGAAPEREL
PAAAGGCPAAALRREAQAAAAGEGDNGPGLQGLSREAPPADDFYDDDDDDDDDDEGEEEE
EAAAAIGYRDNLLFGDEIITNGFHSCESDEDDRASHASSSDWTPRPRIGPYTFVQQHLMI
GTDPRTILKDLLPETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECK
KIIVLTGAGVSVSCGIPDFRSRDGIYARLAVDFPDLPDPQAMFDIEYFRKDPRPFFKFAK
EIYPGQFQPSLCHKFIALSDKEGKLLRNYTQNIDTLEQVAGIQRIIQCHGSFATASCLIC
KYKVDCEAVRGDIFNQVVPRCPRCPADEPLAIMKPEIVFFGENLPEQFHRAMKYDKDEVD
LLIVIGSSLKVRPVALIPSSIPHEVPQILINREPLPHLHFDVELLGDCDVIINELCHRLG
GEYAKLCCNPVKLSEITEKPPRTQKELAHLSELPPTPLNISEGSSSPEGTSPADSSVIVT
LLDQETKSNVDDPDASESKNCVEEKLQEVQTSARSIESVNEQLESPDLKNVASNTGEKNE
RTSVAETVRKCWPARLAKEQISKRLDGNQYLFLPPNRYIFHGAEVYSDSEDDVLSSSSCG
SNSDSGTCQSPSLEEPMEDESEIEEFYNGLEDDADVNERAGATGFGADGGDQEAVNEATS
MKQEATCINYPSNKS
NT seq
2208 nt
NT seq
+upstream
nt +downstream
nt
atggcggacgaggcggcgctcgcctttcagcccggcggctccccctcggcagtgacggct
gagagggaggccccgtcgcctcctgccggggagccgctccgcaagaggccgcggagagac
ggccccggcgtcgggcggagcccgggcgagcccggcggggcggcccccgagcgtgagctg
ccggcggcggccggcggctgcccggcggcggcgctgcggcgggaggcccaggcggcggcg
gccggagaaggagacaatgggccgggtttacagggcctatcccgggaggcgccgccggcc
gacgacttctacgacgacgacgacgacgacgacgacgacgacgagggcgaggaggaggaa
gaggcggcggcggctattgggtaccgagataatctactgtttggtgatgaaatcatcacc
aacggtttccattcgtgtgaaagtgatgaggatgatagagcctcacatgcgagttctagt
gactggactccaagaccacggataggtccatatactttcgttcagcaacatctcatgatt
ggcacagatcctcgaacgattcttaaagatttactaccagaaacaattcctccacctgaa
ttggatgatatgacactgtggcagattgttattaatatcctttcagaaccaccaaaaagg
aaaaaaagaaaagatattaatacaattgaagatgctgtgaaattactgcaagagtgcaaa
aaaataatagttctaactggagctggggtttctgtttcttgtggaatacctgacttcagg
tcaagagatggtatttatgctcgccttgcagtagactttccagaccttccagatcctcaa
gcaatgtttgacattgaatatttcagaaaagatccaagaccattcttcaagtttgcaaag
gaaatatatcctggacaattccaaccatctctttgtcacaaattcatagccttgtcagat
aaggaaggaaaactacttcgcaactatactcagaacatagatacactggaacaggttgca
ggaatccaaaggataattcagtgtcatggttcctttgcaacagcatcttgcctgatttgt
aaatacaaagttgactgtgaagctgtacgaggagatatttttaatcaggtggttcctcga
tgtcctaggtgcccagctgatgaaccacttgctatcatgaaaccagagattgtctttttt
ggtgaaaatttaccagaacagtttcatagagccatgaagtatgacaaagatgaagttgat
cttctcattgttattgggtcttccctgaaagtaagaccagtagcactaattccgagttcc
ataccccatgaagtgcctcagatattaattaatagggaacctttgcctcacctgcatttt
gatgtagagcttcttggagactgtgatgtcattattaatgaattgtgtcacaggttaggt
ggtgaatacgccaaactttgctgcaaccctgtaaagctttcagaaattactgaaaaacct
ccacgaacacaaaaagaattggctcacttgtcagagttgccacccacacccctcaatatt
tcagaaggctcaagttcaccagaaggaacctcaccagcagattcttcagtgattgtcact
cttttagaccaagaaacaaagagtaatgttgatgatccagatgcatctgaatcaaaaaac
tgtgttgaagaaaaattacaggaagtacagacttctgctaggagcattgaaagtgttaat
gaacagttggagagtccggatttgaagaatgttgcctccaatactggggagaaaaatgaa
agaacttcagttgctgaaacagtgagaaaatgctggccagctagactcgcaaaggagcag
attagtaaacggcttgatggtaatcaatatctgtttttaccaccaaaccgttatattttc
catggtgctgaggtatattcagactctgaagatgatgtcttatcctctagttcttgtggc
agtaacagtgatagtggaacatgccagagtccaagtttagaagaacctatggaggatgaa
agtgagattgaagaattttacaatggtttggaagatgatgctgatgttaatgagagagcc
ggagcaactggatttggagctgatggaggtgatcaagaggcagttaatgaagctacatct
atgaaacaggaagcaacatgcattaactatccatcgaacaaatcataa
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