Drosophila melanogaster (fruit fly): Dmel_CG18492 Help Entry Dmel_CG18492      CDS       T00030                                  Gene name Tak1 Definition (RefSeq) TGF-beta activated kinase 1, isoform A   KO K04427   mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25] Organism dme  Drosophila melanogaster (fruit fly) Pathway dme04013   MAPK signaling pathway - fly dme04140   Autophagy - animal dme04214   Apoptosis - fly dme04310   Wnt signaling pathway dme04624   Toll and Imd signaling pathway Brite KEGG Orthology (KO) [BR:dme00001]  09130 Environmental Information Processing   09132 Signal transduction    04013 MAPK signaling pathway - fly     Dmel_CG18492 (Tak1)    04310 Wnt signaling pathway     Dmel_CG18492 (Tak1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     Dmel_CG18492 (Tak1)   09143 Cell growth and death    04214 Apoptosis - fly     Dmel_CG18492 (Tak1)  09150 Organismal Systems   09151 Immune system    04624 Toll and Imd signaling pathway     Dmel_CG18492 (Tak1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:dme01001]     Dmel_CG18492 (Tak1) Enzymes [BR:dme01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.25  mitogen-activated protein kinase kinase kinase      Dmel_CG18492 (Tak1) Protein kinases [BR:dme01001]  Serine/threonine kinases: TKL group   MLK family    Dmel_CG18492 (Tak1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase Motif Other DBs NCBI-GeneID:  39659 NCBI-ProteinID:  NP_524080 FlyBase:  FBgn0026323 UniProt:  Q9V3Q6 LinkDB All DBs Position X AA seq 678 aa AA seqDB search MATASLDALQAAYVDFSEITLREKVGHGSYGVVCKAVWRDKLVAVKEFFASAEQKDIEKE VKQLSRVKHPNIIALHGISSYQQATYLIMEFAEGGSLHNFLHGKVKPAYSLAHAMSWARQ CAEGLAYLHAMTPKPLIHRDVKPLNLLLTNKGRNLKICDFGTVADKSTMMTNNRGSAAWM APEVFEGSKYTEKCDIFSWAIVLWEVLSRKQPFKGIDNAYTIQWKIYKGERPPLLTTCPK RIEDLMTACWKTVPEDRPSMQYIVGVMHEIVKDYTGADKALEYTFVNQQIVTKESDGTVA AQPDSLSSQEGELSPSSTQLTPTTAANANVNAIAISKTTTSSMTENTSSTSSDITPTNSG QLDNNPLFYMVTNRWDAIPEEESNESRNDSFNLTSSAEATQRLETIRNGMILMACKPMEQ LTLDVEANGFDLSPSESSSSSTNAKSDGRERLTVTDTKPVMMTTDLSNNNGGIHAHSNGL LSHANGWQARDEELQEQEHEQEIVNSLDVDVDPDEDENDGTEQSLAEILDPELQPEPPIP NDAESQLIYRDHRHMAKEYLSVDTNLYYAQDFKDKLIVQMDRTEREQKQELLRKMKDKEG LQSLYNNLQQQYASRQLAAGHHPQPHPHPHPNQLQHPHSHPPMHFLQDEGCGLLPGSVCG GSESVEEGWVVIPPHHNA NT seq 2037 nt NT seq  +upstreamnt  +downstreamnt atggccacagcatcgctggacgcactgcaggcagcctatgtggacttcagtgagataaca ctaagagagaaagtcggccatgggtcctacggagtggtctgcaaggccgtttggcgcgac aagctggttgccgtcaaggagttcttcgccagcgccgagcagaaggacatcgagaaggag gtgaagcagttgtcgcgcgtgaagcacccgaacatcatcgctctgcacgggatatcctcg taccagcaggccacctacctgataatggagttcgccgaaggtggatcgctgcacaacttc cttcacggcaaggtgaagccggcatattctctggcccacgccatgagctgggcgcgccaa tgtgcagagggtctggcatatttgcatgccatgacgccaaaaccactaatacatcgcgac gtgaagccgctgaacctgctcttgaccaacaagggacgcaatctgaagatatgcgacttc ggcacggtggcggacaagtcgaccatgatgaccaacaatcgcggcagtgccgcttggatg gcgcccgaggtcttcgaaggctccaagtatacggagaagtgtgacatttttagctgggcc attgttctatgggaggttctgtccaggaagcagccctttaaaggcatcgacaatgcctac accatccagtggaagatctacaagggtgaacgcccgccgctgctgaccacttgccccaag cgcatcgaggacctgatgaccgcctgctggaaaacggtgcccgaggatcgcccgtcgatg cagtacatagtgggcgttatgcacgagatcgtcaaggactatacgggggcggacaaggcc ctggaatacacgtttgttaatcaacagattgtcaccaaagagagcgacggcacggtggcc gctcaaccggatagcctcagttcgcaggagggggaactgagcccctcgtccacacagtta acaccgacaacggcggccaacgccaatgtgaacgcgatagcaatatcaaaaacaacgact agctcaatgaccgaaaatacctcatcaacatcatcggacatcacgccgacgaactcgggc caactggacaataatccgctattctatatggtcaccaatcgctgggacgcgattcccgag gaggagagcaacgagagccggaacgatagcttcaacctcacctcgtcggctgaggccact cagcgcctcgaaacgatccggaacggcatgatcctgatggcctgcaagcccatggagcag ctcaccctcgacgtggaggcgaatggctttgatctgagtcccagcgaaagcagcagcagc agcacgaacgcaaagagcgatggccgcgaacgactcacggtgacggacaccaagccggtg atgatgaccacggatctgtccaacaacaacggcggcatccacgcccactcgaacggactg ctgagccatgcgaatggttggcaagcaagagatgaggagctgcaggagcaagagcatgag caggagattgtcaactcgttggacgtcgacgtggatcccgacgaggatgagaacgacggc accgaacagtcactggccgagattcttgatccggagctccagccagagccgccgataccc aacgatgccgaatcgcagctcatctaccgggaccaccgacacatggccaaggagtacctg agcgtcgacacgaacctctactacgcgcaggacttcaaggacaagctcatcgtgcagatg gaccgaaccgagcgcgaacagaagcaggagcttctgcgcaagatgaaggacaaggagggt cttcagagtctttacaacaatctgcagcagcagtacgcttcacgccaacttgcggccggc catcatccgcaacctcatcctcatccgcatccaaatcagcttcagcatccacactcacat ccgcctatgcatttcctgcaggatgagggctgtggactgctgcccggatcggtgtgcgga ggctctgagtccgtggaagaaggctgggtggtcatcccaccgcatcacaatgcgtag

Drosophila melanogaster (fruit fly): Dmel_CG31421 Help Entry Dmel_CG31421      CDS       T00030                                  Gene name Takl1 Definition (RefSeq) Tak1-like 1   KO K04427   mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25] Organism dme  Drosophila melanogaster (fruit fly) Pathway dme04013   MAPK signaling pathway - fly dme04140   Autophagy - animal dme04214   Apoptosis - fly dme04310   Wnt signaling pathway dme04624   Toll and Imd signaling pathway Brite KEGG Orthology (KO) [BR:dme00001]  09130 Environmental Information Processing   09132 Signal transduction    04013 MAPK signaling pathway - fly     Dmel_CG31421 (Takl1)    04310 Wnt signaling pathway     Dmel_CG31421 (Takl1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     Dmel_CG31421 (Takl1)   09143 Cell growth and death    04214 Apoptosis - fly     Dmel_CG31421 (Takl1)  09150 Organismal Systems   09151 Immune system    04624 Toll and Imd signaling pathway     Dmel_CG31421 (Takl1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:dme01001]     Dmel_CG31421 (Takl1) Enzymes [BR:dme01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.25  mitogen-activated protein kinase kinase kinase      Dmel_CG31421 (Takl1) Protein kinases [BR:dme01001]  Serine/threonine kinases: TKL group   MLK family    Dmel_CG31421 (Takl1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr Pkinase_fungal APH FTA2 Pox_ser-thr_kin Motif Other DBs NCBI-GeneID:  318725 NCBI-ProteinID:  NP_732554 FlyBase:  FBgn0046689 UniProt:  P83104 LinkDB All DBs Position 3R AA seq 393 aa AA seqDB search MVKQVDFAEVKLSEKFLGAGSGGAVRKATFQNQEIAVKIFDFLEETIKKNAEREITHLSE IDHENVIRVIGRASNGKKDYLLMEYLEEGSLHNYLYGDDKWEYTVEQAVRWALQCAKALA YLHSLDRPIVHRDIKPQNMLLYNQHEDLKICDFGLATDMSNNKTDMQGTLRYMAPEAIKH LKYTAKCDVYSFGIMLWELMTRQLPYSHLENPNSQYAIMKAISSGEKLPMEAVRSDCPEG IKQLMECCMDINPEKRPSMKEIEKFLGEQYESGTDEDFIKPLDEDTVAVVTYHVDSSGSR IMRVDFWRHQLPSIRMTFPIVKREAERLGKTVVREMAKAAADGDREVRRAEKDTERETSR AAHNGERETRRAGQDVGRETVRAVKKIGKKLRF NT seq 1182 nt NT seq  +upstreamnt  +downstreamnt atggtcaagcaagtggattttgcggaggtgaagctcagtgagaaatttctcggagctgga tctggtggagcggtgcgcaaagccacctttcaaaatcaggagattgcagtaaagatattt gatttccttgaggaaacaatcaaaaagaatgcagagagggaaatcacacatttgtcggag atcgaccacgaaaacgttatcagggtgatcgggagggccagcaatggaaagaaggactac ttgttgatggagtacctggaggaggggtccctccacaactacctctatggcgatgacaag tgggagtacaccgtggagcaagcggttcgctgggcactccaatgcgccaaggccttagca tacttgcattcgttggatcgaccgattgttcaccgcgatattaagccgcaaaacatgctt ttatataatcagcatgaagacttaaagatttgtgactttggcctggcgacggatatgtcc aataataagaccgatatgcaaggaacattgaggtatatggctcccgaggccattaagcac ttaaagtatacggctaagtgtgatgtgtacagctttggaataatgctctgggagctgatg acacgtcaattgccatatagtcacttggaaaaccccaacagccagtacgccattatgaaa gctatcagttcaggcgaaaaacttccaatggaagcagtaagatccgattgcccagagggt atcaagcaattaatggaatgttgcatggatataaatcccgaaaagcgcccctctatgaag gagatcgaaaagttccttggcgaacagtatgaatccggcactgacgaggactttatcaag cctttggatgaggataccgtggctgtggtgacctaccatgtggattcgtccggcagcagg ataatgcgtgttgatttctggcgacatcagttgccatcgatccgcatgacttttccgata gtgaaacgggaagccgaaagattgggaaagaccgttgtcagagaaatggccaaggcggcg gcggatggagatcgggaagttcggcgggctgagaaggacacggagcgtgaaacctcgagg gctgcccacaatggagagcgggaaacgcggagagcgggtcaggatgtgggtcgtgaaact gtacgggcggtcaagaaaataggaaagaaactgcgcttctaa

Drosophila melanogaster (fruit fly): Dmel_CG4803 Help Entry Dmel_CG4803       CDS       T00030                                  Gene name Takl2 Definition (RefSeq) Tak1-like 2   KO K04427   mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25] Organism dme  Drosophila melanogaster (fruit fly) Pathway dme04013   MAPK signaling pathway - fly dme04140   Autophagy - animal dme04214   Apoptosis - fly dme04310   Wnt signaling pathway dme04624   Toll and Imd signaling pathway Brite KEGG Orthology (KO) [BR:dme00001]  09130 Environmental Information Processing   09132 Signal transduction    04013 MAPK signaling pathway - fly     Dmel_CG4803 (Takl2)    04310 Wnt signaling pathway     Dmel_CG4803 (Takl2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     Dmel_CG4803 (Takl2)   09143 Cell growth and death    04214 Apoptosis - fly     Dmel_CG4803 (Takl2)  09150 Organismal Systems   09151 Immune system    04624 Toll and Imd signaling pathway     Dmel_CG4803 (Takl2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:dme01001]     Dmel_CG4803 (Takl2) Enzymes [BR:dme01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.25  mitogen-activated protein kinase kinase kinase      Dmel_CG4803 (Takl2) Protein kinases [BR:dme01001]  Serine/threonine kinases: TKL group   MLK family    Dmel_CG4803 (Takl2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr APH Motif Other DBs NCBI-GeneID:  42692 NCBI-ProteinID:  NP_651090 FlyBase:  FBgn0039015 UniProt:  Q9VCV0 LinkDB All DBs Position 3R AA seq 281 aa AA seqDB search MSAPVEGVPYEEIQTKELIGTGFYGSVYRAVWRNREIALKRIREGCEDKKIEREIYQLTK ASHVNIVELYGTSRHEGCALLLMEFVDGGSLSSFLHAKSKPSYSHAHAFNWAHQIAQGIA YLHGMQPKAVIHRDIKPLNTLLCEKGLKLKICDFGTVVDLSQSISCNAGTCRYKAPEVLQ GNKPDEKCDVYSWAITFWEILSRKEPFEQYNTLFELYMAINEGERPDLSCIMSGCPADIV ALLYASWDPDISKRFSMELISQSMGRILSEAGSIPPLDFYS NT seq 846 nt NT seq  +upstreamnt  +downstreamnt atgtccgctcctgtagagggtgttccctatgaggagatccagacaaaagagcttataggc accggattctatggcagcgtatacagggcggtctggagaaatcgtgagatcgcgctgaag agaattcgcgagggatgtgaggataaaaagattgaaagagagatctaccagctgacaaag gccagccatgtcaacatagttgagctctacggcacatcgaggcacgagggatgcgccctg ctgttgatggaattcgtagacggtggatctctgtccagttttctgcacgcgaaaagcaag ccaagttattcgcatgcccacgccttcaactgggcgcatcagatcgctcagggcatagcc tatctgcatggcatgcagccgaaagcagtaattcatcgcgatataaagccactcaataca ctgctatgcgagaagggactcaaactgaagatttgcgatttcggaactgttgtggaccta tcccaatcgatatcgtgcaatgcgggcacctgcagatacaaagcgcccgaggttctacaa ggaaataaacccgatgaaaagtgcgatgtgtatagttgggctattaccttttgggaaata ttgtcgcgcaaggagccatttgagcaatataatacgctttttgaactgtacatggctatt aatgaaggcgagagaccggatttaagttgcattatgtctggctgccccgcggatatagtt gctcttttgtacgcttcttgggatccggatatcagcaaaagattttctatggaactgatt tcccaaagcatgggtagaatcctaagtgaggcgggatccattccaccactggatttttac tcataa

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