| Entry |
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| Name |
Valganciclovir (INN) |
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| Formula |
C14H22N6O5
|
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| Exact mass |
354.1652
|
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| Mol weight |
354.36
|
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| Structure |
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| Simcomp |
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| Class |
Antiviral
DG01937 Anti-cytomegalovirus agent
|
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| Remark |
| Product (DG00649): | D03256<JP/US> |
|
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| Efficacy |
Antiviral, DNA polymerase ihibitor |
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| Comment |
Active form of prodrug: Ganciclovir [DR: D00333]
Acyclovir type
|
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| Target |
HCMV DNA polymerase [KO: K18964] |
|---|
| Pathway |
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| Interaction |
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J05 ANTIVIRALS FOR SYSTEMIC USE
J05A DIRECT ACTING ANTIVIRALS
J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
J05AB14 Valganciclovir
D02495 Valganciclovir (INN)
Drug groups [BR:br08330]
Antiviral
DG01937 Anti-cytomegalovirus agent
DG00649 Valganciclovir
D02495 Valganciclovir
Antimicrobials [BR:br08307]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
D02495 Valganciclovir (INN)
Prodrugs [br08324.html]
D02495
Drug groups [BR:br08330]
Antiviral
DG01937 Anti-cytomegalovirus agent
DG00649 Valganciclovir
Antimicrobials abbreviations [BR:br08327]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
DG00649 Valganciclovir
Prodrugs [br08324.html]
DG00649
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 25
1 C8y C 25.9159 -13.2779
2 C8y C 25.9037 -11.8862
3 N4y N 24.6925 -13.8432
4 N4x N 27.2142 -13.9737
5 N5x N 24.5569 -11.5468
6 C8y C 27.0457 -11.1204
7 C8x C 23.7876 -12.7095
8 C8y C 28.3556 -13.2037
9 N5x N 28.3394 -11.7424
10 O5x O 27.0335 -9.7288
11 N1a N 29.6498 -13.8297
12 C1b C 24.6925 -15.2432
13 O2a O 23.4862 -15.9399
14 C1c C 22.3078 -15.2597
15 C1b C 21.1120 -15.9503
16 C1b C 22.3076 -13.8602
17 O7a O 19.9247 -15.2650
18 C7a C 18.7336 -15.9531
19 C1c C 17.5439 -15.2664
20 C1c C 16.3540 -15.9538
21 O1a O 21.1119 -13.1699
22 O6a O 18.7337 -17.3598
23 C1a C 15.1637 -15.2667
24 C1a C 16.3541 -17.3598
25 N1a N 17.5435 -13.8603
BOND 26
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 4 8 1
8 6 9 1
9 6 10 2
10 8 11 1
11 5 7 2
12 8 9 2
13 3 12 1
14 12 13 1
15 13 14 1
16 14 15 1
17 14 16 1
18 15 17 1
19 17 18 1
20 18 19 1
21 19 20 1
22 16 21 1
23 18 22 2
24 20 23 1
25 20 24 1
26 19 25 1 #Down
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