KEGG   DRUG: Dutogliptin
Entry
D09333                      Drug                                   

Name
Dutogliptin (USAN)
Formula
C10H20BN3O3
Exact mass
241.1598
Mol weight
241.0951
Structure
Class
Antidiabetic agent
 DG01601  DPP-4 inhibitor
 DG02044  Hypoglycemics
  DG01601  DPP-4 inhibitor
Remark
Chemical structure group: DG01282
Efficacy
Antidiabetic, Dipeptidyl peptidase-4 (DPP-4) inhibitor
Comment
Treatment of type 2 diabetes
Target
DPP4 (CD26) [HSA:1803] [KO:K01278]
  Pathway
hsa04974  Protein digestion and absorption
Interaction
Brite
Target-based classification of drugs [BR:br08310]
 Enzymes
  Hydrolases (EC3)
   Peptidyl-peptidases
    DPP4 (CD26)
     D09333  Dutogliptin (USAN)
Other DBs
CAS: 852329-66-9
PubChem: 96026013
ChEMBL: CHEMBL4296719
LinkDB
KCF data

ATOM        17
            1   N1x N     8.8200  -25.4800
            2   C1x C     9.2400  -26.7400
            3   C1x C    10.6400  -26.7400
            4   C1y C    11.0600  -25.4100
            5   C1x C     9.9400  -24.5700
            6   N1b N    12.2500  -24.7100
            7   C1b C    13.4400  -25.4100
            8   C5a C    14.6300  -24.7100
            9   N1y N    15.8200  -25.4100
            10  O5a O    14.6300  -23.3100
            11  C1x C    16.1700  -26.8100
            12  C1x C    17.5700  -26.8100
            13  C1x C    18.0600  -25.5500
            14  C1y C    17.0100  -24.6400
            15  Z   B    17.0378  -23.2434
            16  O1a O    18.2438  -22.5784
            17  O1a O    15.8177  -22.5062
BOND        18
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     6   7 1
            7     4   6 1 #Down
            8     7   8 1
            9     8   9 1
            10    8  10 2
            11    9  11 1
            12   11  12 1
            13   12  13 1
            14   13  14 1
            15    9  14 1
            16   14  15 1 #Down
            17   15  16 1
            18   15  17 1

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