KEGG   DRUG: Ezetimibe and simvastatin
Entry
D10257            Mixture   Drug                                   

Name
Ezetimibe and simvastatin;
Vytorin (TN)
Product
  Generic
Component
Ezetimibe [DR:D01966], Simvastatin [DR:D00434]
Class
Cardiovascular agent
 DG01946  Hypolipidemic agent
Remark
ATC code: C10BA02
Product: D10257<US>
Efficacy
Antihyperlipidemic
  Disease
Hyperlipidemia [DS:H01635]
Homozygous familial hypercholesterolemia [DS:H00155]
Comment
Simvastatin is a substrate for OATP1B1.
Metabolism
Transporter: SLCO1B1 [HSA:10599]
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C10 LIPID MODIFYING AGENTS
   C10B LIPID MODIFYING AGENTS, COMBINATIONS
    C10BA HMG CoA reductase inhibitors in combination with other lipid modifying agents
     C10BA02 Simvastatin and ezetimibe
      D10257  Ezetimibe and simvastatin <US>
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Dyslipidemics, Other
   Ezetimibe/ Simvastatin
    D10257  Ezetimibe and simvastatin
Drug metabolizing enzymes and transporters [br08309.html]
 Drug transporters
  D10257
Other DBs
PubChem: 163312288
LinkDB

» Japanese version   » Back

DBGET integrated database retrieval system