EC 126.96.36.199 Enzyme
diethyl 2-methyl-3-oxosuccinate reductase
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP+ = diethyl 2-methyl-3-oxosuccinate + NADPH + H+ [RN:
diethyl (2R,3R)-2-methyl-3-hydroxysuccinate [CPD:
diethyl 2-methyl-3-oxosuccinate [CPD:
Also acts on diethyl (2S,3R)-2-methyl-3-hydroxysuccinate; and on the corresponding dimethyl esters.
EC 188.8.131.52 created 1990
Furuichi, A., Akita, H., Matsukura, H., Oishi, T. and Horikoshi, K.
Purification and properties of an asymmetric reduction of diethyl 2-methyl-3-oxosuccinate in Saccharomyces fermentati.
Agric Biol Chem 51:293-299 (1987)
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