Entry
Name
D-arabinitol dehydrogenase (NADP+);
NADP+-dependent D-arabitol dehydrogenase;
ARD1p;
D-arabitol dehydrogenase 1
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-arabinitol:NADP+ oxidoreductase
Reaction(IUBMB)
(1) D-arabinitol + NADP+ = D-xylulose + NADPH + H+ [RN:
R07143 ];
(2) D-arabinitol + NADP+ = D-ribulose + NADPH + H+ [RN:
R07144 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme from the rust fungus Uromyces fabae can use D-arabinitol and D-mannitol as substrates in the forward direction and D-xylulose, D-ribulose and, to a lesser extent, D-fructose as substrates in the reverse direction. This enzyme carries out the reactions of both EC
1.1.1.11 , D-arabinitol 4-dehydrogenase and EC
1.1.1.250 , D-arabinitol 2-dehydrogenase, but unlike them, uses NADP+ rather than NAD+ as cofactor. D-Arabinitol is capable of quenching reactive oxygen species involved in defense reactions of the host plant.
History
EC 1.1.1.287 created 2005
Pathway
ec00040 Pentose and glucuronate interconversions
Orthology
K17818 D-arabinitol dehydrogenase (NADP+)
Genes
BFO : 118404134 118407503 118409407 118409409
BBEL : 109469863 109485904 109485905 109485906
AROA : 105690461 105690489 105690519 105690587
TCA : 656777 656868 656956
LDC : 111512233 111512234 111512235
APLN : 108733757 108743068
PPYR : 116161257 116162229 116162524
CCRN : 123300054 123300533 123300766
MQU : 128995239 128995334 128995975 129004735
TPAL : 117641356 117653082
CSEC : 111868664 111869992
PPOI : 119102375 119107173 119113973
LGI : LOTGIDRAFT_122580 LOTGIDRAFT_159773 LOTGIDRAFT_188066
PVUL : 126816201 126816202 130010225
ATEN : 116287780 116298403
PDAM : 113684290 113684326
SPIS : 111343963 111343964
PSCO : LY89DRAFT_746517 LY89DRAFT_770545
ANG : An01g03480 An05g02000
ALUC : AKAW2_20514S AKAW2_81343A
APUU : APUU_11613S APUU_21187S
TRG : TRUGW13939_00501 TRUGW13939_01187
CCAC : CcaHIS019_0507490(CcaverHIS019_0507490)
TVS : TRAVEDRAFT_30336 TRAVEDRAFT_73393
DSQ : DICSQDRAFT_162455 DICSQDRAFT_179082 DICSQDRAFT_181925 DICSQDRAFT_54950
PCO : PHACADRAFT_142124 PHACADRAFT_253802
SHS : STEHIDRAFT_103570 STEHIDRAFT_84864
HIR : HETIRDRAFT_156927 HETIRDRAFT_461044
PSQ : PUNSTDRAFT_52317 PUNSTDRAFT_68061
FME : FOMMEDRAFT_103362 FOMMEDRAFT_165934
GTR : GLOTRDRAFT_104555 GLOTRDRAFT_111731 GLOTRDRAFT_63257
ABP : AGABI1DRAFT116829(AGABI1DRAFT_116829) AGABI1DRAFT46050(AGABI1DRAFT_46050)
ABV : AGABI2DRAFT145143(AGABI2DRAFT_145143) AGABI2DRAFT194619(AGABI2DRAFT_194619)
PCUB : JR316_0010009 JR316_0010045
MRR : Moror_10616 Moror_7142 Moror_7157
MORE : E1B28_004931 E1B28_008305
SCM : SCHCO_02636705(SCHCODRAFT_02636705)
CPUT : CONPUDRAFT_109782 CONPUDRAFT_92430
SLA : SERLADRAFT_345461 SERLADRAFT_457148
PGR : PGTG_20122 PGTG_22572
ETM : CE91St48_33740(ydjJ)
» show all
Taxonomy
Reference
Authors
Link T, Lohaus G, Heiser I, Mendgen K, Hahn M, Voegele RT
Title
Characterization of a novel NADP(+)-dependent D-arabitol dehydrogenase from the plant pathogen Uromyces fabae.
Journal
Sequence
Other DBs
ExPASy - ENZYME nomenclature database: 1.1.1.287
LinkDB
All DBs