Entry |
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Name |
norsolorinic acid ketoreductase;
aflD (gene name);
nor-1 (gene name)
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Class |
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
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Sysname |
(1'S)-averantin:NADP+ oxidoreductase
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Reaction(IUBMB) |
(1'S)-averantin + NADP+ = norsolorinic acid + NADPH + H+ [RN: R10309]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
Involved in the synthesis of aflatoxins in the fungus Aspergillus parasiticus.
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History |
EC 1.1.1.349 created 2013
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Pathway |
ec01110 | Biosynthesis of secondary metabolites |
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Orthology |
K17644 | norsolorinic acid ketoreductase |
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Genes |
PBEL: | QC761_207200 QC761_207370(NOR1) |
PPSD: | QC762_207200 QC762_207370(NOR1) |
PPEI: | PpBr36_02616 PpBr36_09608 |
PGRI: | PgNI_02173 PgNI_10101 |
FVN: | FVRRES_07755 FVRRES_10990 |
NHE: | NECHADRAFT_19049 NECHADRAFT_44851 NECHADRAFT_94977 |
FFC: | NCS54_00901400 NCS54_00908600 NCS54_00917600 NCS54_00932700 |
FKR: | NCS57_00920500 NCS57_00926800 NCS57_00952200 NCS57_01357800 |
TRE: | TRIREDRAFT_103113 TRIREDRAFT_105884 |
TRR: | M419DRAFT_7213 M419DRAFT_88601 |
VAL: | VDBG_02925 VDBG_06335 |
CFJ: | CFIO01_09694 CFIO01_11244 |
CLUP: | CLUP02_11195 CLUP02_13454 CLUP02_15568 |
CHIG: | CH63R_01668 CH63R_08584 |
ELA: | UCREL1_771 UCREL1_8646 |
PFY: | PFICI_02604 PFICI_13483 PFICI_14974 |
BFU: | BCIN_09g00680 BCIN_13g02220 |
PSCO: | LY89DRAFT_589972 LY89DRAFT_642918 |
GLZ: | GLAREA_06058 GLAREA_09658 GLAREA_12088 |
AOR: | AO090023000875 AO090026000011 AO090038000063 |
ANG: | An02g01090 An12g03210 An12g06400 |
AFV: | AFLA_006309 AFLA_007227 AFLA_012318 |
APUU: | APUU_12296S APUU_20041S APUU_61047A |
AALT: | CC77DRAFT_1088875 CC77DRAFT_546209 |
SCM: | SCHCO_02748978(SCHCODRAFT_02748978) |
» show all
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Reference |
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Authors |
Yabe K, Matsuyama Y, Ando Y, Nakajima H, Hamasaki T |
Title |
Stereochemistry during aflatoxin biosynthesis: conversion of norsolorinic acid to averufin. |
Journal |
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Reference |
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Authors |
Zhou R, Linz JE |
Title |
Enzymatic function of the nor-1 protein in aflatoxin biosynthesis in Aspergillus parasiticus. |
Journal |
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Sequence |
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Other DBs |
ExPASy - ENZYME nomenclature database: | 1.1.1.349 |
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LinkDB |
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