KEGG   ENZYME: 1.12.1.3
Entry
EC 1.12.1.3                 Enzyme                                 
Name
hydrogen dehydrogenase (NADP+);
NADP+-linked hydrogenase;
NADP+-reducing hydrogenase;
hydrogenase (ambiguous);
hydrogenase I (ambiguous)
Class
Oxidoreductases;
Acting on hydrogen as donor;
With NAD+ or NADP+ as acceptor
Sysname
hydrogen:NADP+ oxidoreductase
Reaction(IUBMB)
H2 + NADP+ = H+ + NADPH [RN:R07181]
Reaction(KEGG)
R07181
Substrate
H2 [CPD:C00282];
NADP+ [CPD:C00006]
Product
H+ [CPD:C00080];
NADPH [CPD:C00005]
Comment
The protein from the bacterium Desulfovibrio fructosovorans is an iron-sulfur protein that exclusively functions as a hydrogen dehydrogenase [1], while the enzyme from the archaeon Pyrococcus furiosus is a nickel, iron, iron-sulfur protein, that is part of a heterotetrameric complex where the alpha and delta subunits function as a hydrogenase while the beta and gamma subunits function as sulfur reductase (EC 1.12.98.4, sulfhydrogenase). Different from EC 1.12.1.5, hydrogen dehydrogenase [NAD(P)+].
History
EC 1.12.1.3 created 2002, modified 2013
Orthology
K17992  NADP-reducing hydrogenase subunit HndB
K17993  sulfhydrogenase subunit alpha
K17994  sulfhydrogenase subunit delta
K18330  NADP-reducing hydrogenase subunit HndA
K18331  NADP-reducing hydrogenase subunit HndC
K18332  NADP-reducing hydrogenase subunit HndD
Genes
BHO: D560_2878
BHM: D558_2856
OCA: OCAR_5286
OCG: OCA5_c26870
OCO: OCA4_c26860
RRF: F11_01565
GPI: GPICK_09395
GEB: GM18_1856 GM18_1857 GM18_1858 GM18_1859
GEO: Geob_0218(bamH-1) Geob_0234(bamH-2)
PCA: Pcar_1602(hndA-3) Pcar_1603(hndB-3) Pcar_1604(hndC-3) Pcar_1605(hndD-3) Pcar_1633(hndD-2) Pcar_1634(hndC-2) Pcar_1635(hndB-2) Pcar_1636(hndA-2) Pcar_1844(hndC-1) Pcar_1845(hndB-1) Pcar_1846(hndA-1) Pcar_2708(hndC-5)
PACE: A6070_04705 A6070_07085 A6070_07090 A6070_07095 A6070_07100 A6070_07285 A6070_07950 A6070_07955 A6070_07960 A6070_07965 A6070_09010
PEF: A7E78_02215 A7E78_02220 A7E78_02225 A7E78_02230 A7E78_06775 A7E78_06780
PPD: Ppro_3516 Ppro_3517 Ppro_3518
DMA: DMR_02450 DMR_02460 DMR_02470(nuoF) DMR_02480
DCB: C3Y92_00825 C3Y92_00830 C3Y92_00835 C3Y92_00840
DAL: Dalk_2271
DAT: HRM2_16520
DTO: TOL2_C03720(bamH1) TOL2_C28870 TOL2_C28900 TOL2_C41380(bamH2) TOL2_C43510(bamH3)
DOV: DSCO28_20310 DSCO28_66020
DALK: DSCA_31590 DSCA_31610
DML: Dmul_28600(nuoF3) Dmul_34230(morB)
DLI: dnl_05790 dnl_18600 dnl_18610(nuoF) dnl_49300
DMM: dnm_042000(nuoF1) dnm_042010 dnm_042020
DEK: DSLASN_10770 DSLASN_26630 DSLASN_26640 DSLASN_26650 DSLASN_26660
SAT: SYN_00152 SYN_01370
DTI: Desti_1918 Desti_2752 Desti_2753
SFU: Sfum_0844
DAX: FDQ92_01160(nuoF)
DBR: Deba_0481 Deba_0785 Deba_1519 Deba_1520 Deba_2120
THET: F1847_07590
TNR: Thena_1510
TACI: TDSAC_1040
OTE: Oter_1545
SLOM: PXH66_06815
OBA: ASA1KI_43220
MKC: kam1_1223
VBS: EGM51_01930(nuoF) EGM51_01935
TTF: THTE_2881 THTE_3843
KST: KSMBR1_0596(nuoF_1) KSMBR1_1330(nuoF_2)
BROC: IPI25_00220(nuoE) IPI25_07695(nuoF)
PBU: L21SP3_00034(hndD_1) L21SP3_00309(hndD_2) L21SP3_00310(hndC_3)
PBP: STSP1_00009(hndD_1) STSP1_00010(hndC_1) STSP1_01250(hndD_2)
PBAS: SMSP2_01580(hndB) SMSP2_01581(hndC_2) SMSP2_01582(hndD_2) SMSP2_01657(hndD_3)
ALUS: STSP2_01432(hndB) STSP2_01433(hndC) STSP2_01434(hndD)
VBL: L21SP4_00378 L21SP4_00379 L21SP4_00380 L21SP4_01302(hndD_2)
TAER: GT409_10650 GT409_10655 GT409_10660 GT409_14290
LBV: JYG24_03375 JYG24_04795
LBAC: LJT99_08685
VAI: BU251_02010 BU251_02015 BU251_02020
TBE: Trebr_0332 Trebr_0333
TPI: TREPR_3595
TPED: TPE_0917 TPE_2309
TPK: JO40_11355
TRZ: GWP43_12150
TRC: DYE49_00610 DYE49_00615 DYE49_00620
TRP: ABH09_11120 ABH09_11130
BPAA: K7I13_10510 K7I13_10520
SSM: Spirs_0474 Spirs_3688 Spirs_3689
STA: STHERM_c06260 STHERM_c13740 STHERM_c13750 STHERM_c13760
STQ: Spith_0640 Spith_1507 Spith_1508 Spith_1509
SFC: Spiaf_1750 Spiaf_2407 Spiaf_2409
SPER: EW093_05445 EW093_05450
SLR: L21SP2_0274 L21SP2_0275
OCK: EXM22_15350 EXM22_15355(nuoF) EXM22_15360
ECUL: PVA46_04200
ENEM: PVA44_05530
EET: PVA45_05775
SBU: SpiBuddy_2313 SpiBuddy_2314
SGP: SpiGrapes_2477 SpiGrapes_2478
SASS: MUG09_08965 MUG09_12690 MUG09_12700
SCC: Spico_0354
TAZ: TREAZ_3248 TREAZ_3249
SCD: Spica_2775
BHC: JFL75_09000 JFL75_09005
TPX: Turpa_2746
BHY: BHWA1_02502(hymC) BHWA1_02503(nuoF)
BHD: BHYOB78_03730 BHYOB78_03735
BRM: Bmur_2160
BIP: Bint_0726(hymC) Bint_0727(nuoF)
BHP: BHAMNSH16_10855 BHAMNSH16_10860
TAQU: KDW03_01340 KDW03_01350
GEX: GETHOR_22120
GEP: Q9293_03605 Q9293_13405 Q9293_13410(nuoE)
GET: QOZ81_000696 QOZ81_002489
MSIL: METEAL_03840 METEAL_13880 METEAL_13890 METEAL_24020
MSEA: METESE_03910 METESE_12970 METESE_17730
EMI: Emin_0532 Emin_0533
EPM: Dip510_001264
PPRX: Dip518_001583
EPO: Epro_0734(hydA) Epro_0735(hydB) Epro_0736
BTH: BT_0123 BT_0124 BT_0125
BTHO: Btheta7330_03239(hndC) Btheta7330_03240(hndD) Btheta7330_03241(hndA)
BXY: BXY_41360 BXY_41370 BXY_41380
BOA: Bovatus_04980(hndA) Bovatus_04981(hndD) Bovatus_04982(hndC)
BCEL: BcellWH2_04988(hndC) BcellWH2_04989(hndD) BcellWH2_04990(hndA)
BCAC: CGC64_09630 CGC64_09635 CGC64_09640
BHF: C3V43_03950 C3V43_03955 C3V43_03960
BIS: DXK01_013735 DXK01_013740 DXK01_013745(nuoE)
BFE: K6V30_13375(nuoE) K6V30_13380 K6V30_13385
BNO: K8P02_07460 K8P02_07465 K8P02_07470
BFC: BacF7301_14380(nuoE) BacF7301_14385 BacF7301_14390
BSAL: K6V25_15505(nuoF) K6V25_15510 K6V25_15515(nuoE)
BVU: BVU_0396
PBT: ING2E5B_2397 ING2E5B_2398(hndC) ING2E5B_2399(hndD) ING2E5B_2400
PMUC: ING2E5A_0853(hndB) ING2E5A_0854(hndC) ING2E5A_0855(hndD) ING2E5A_0856(hndA)
PET: PEIBARAKI_6525 PEIBARAKI_6526 PEIBARAKI_6527 PEIBARAKI_6528
PSAC: PSM36_3019 PSM36_3020(hndD) PSM36_3021(hndC) PSM36_3022
PROJ: KDN43_02040(nuoE) KDN43_02045 KDN43_02050(nuoF) KDN43_02055 KDN43_02090
PDI: BDI_1042 BDI_1043 BDI_1044 BDI_1045
PARC: CI960_08930 CI960_08935 CI960_08940 CI960_08945
PMER: INE87_00694(hndA) INE87_00695(hndD) INE87_00696(hndC) INE87_00697(hndB)
PGOL: K6V26_09170 K6V26_09175 K6V26_09180 K6V26_09185
PJO: LK449_07260 LK449_07265 LK449_07270 LK449_07275
PFAI: NXY11_08570 NXY11_08575 NXY11_08580 NXY11_08585
OSP: Odosp_0184 Odosp_0185 Odosp_0186 Odosp_0187
BUY: D8S85_07440 D8S85_07445 D8S85_07450 D8S85_07455
BVIR: I6J59_09400 I6J59_09405 I6J59_09410 I6J59_09415
BFH: F1611_03285 F1611_03290 F1611_03295 F1611_03300
RBC: BN938_1638 BN938_2212 BN938_2258
TTZ: FHG85_08335 FHG85_08495 FHG85_09610(nuoE) FHG85_09615 FHG85_09620 FHG85_09625 FHG85_09660
BLQ: L21SP5_00769(hndB) L21SP5_00770(hndC_2) L21SP5_00771(hndD_1) L21SP5_00772(hndA_2) L21SP5_00830(hndD_2)
BACC: BRDCF_p1395(nuoE2) BRDCF_p1396(nuoG) BRDCF_p1397(nuoF2) BRDCF_p1398 BRDCF_p1719
DORI: FH5T_02925 FH5T_03065 FH5T_03070 FH5T_03075 FH5T_03080
DRC: G0Q07_16470 G0Q07_16595 G0Q07_16600 G0Q07_16605 G0Q07_16610
MCOS: GM418_18965 GM418_18970 GM418_18975 GM418_18980 GM418_20635
ANF: AQPE_3191 AQPE_3192 AQPE_3193 AQPE_3194 AQPE_5015
HLAM: K4L44_02470 K4L44_02475 K4L44_02480 K4L44_02485
HXY: K5X82_16770 K5X82_16775 K5X82_16780 K5X82_16785
GHY: ACOIT5_02335 ACOIT5_02340 ACOIT5_02345 ACOIT5_02350(nuoE) ACOIT5_18740
ASX: CDL62_11530 CDL62_11585 CDL62_11590 CDL62_11595 CDL62_11600
MBAS: ALGA_2626 ALGA_2627 ALGA_2628 ALGA_2629 ALGA_3125
FLS: GLV81_05450
LUT: Lupro_00310
IAL: IALB_0531(hydA)
MRO: MROS_2482
CACI: CLOAM1181 CLOAM1183(hymB) CLOAM1184
FML: FMIA91_17520 FMIA91_19710
CPO: COPRO5265_0177 COPRO5265_0179 COPRO5265_0180 COPRO5265_0181
CEX: CSE_11940 CSE_11960 CSE_11970
CNI: Calni_1549
CABY: Cabys_3677 Cabys_3678
DTH: DICTH_0768
DTU: Dtur_0918
TYE: THEYE_A1727
TOB: V4D31_06035
TAUT: V4D30_01355
DTP: JZK55_05510 JZK55_11800 JZK55_21900 JZK55_21910 JZK55_21920
NLI: G3M70_15045
ALAM: RT761_02739(hndD_2)
TVX: QBE54_04025 QBE54_04045
ATHO: M15_12720 M15_12760
PAEQ: R50912_06580 R50912_06585
PAEA: R70723_15795 R70723_15800
PAEE: R70331_15235 R70331_15240
PBAC: HUB98_24435
PTJ: JRJ22_12795(nuoF) JRJ22_12800
LRN: CMV25_02440 CMV25_02445
EGV: EGCR1_07010 EGCR1_07015
EAV: EH197_17435(nuoF) EH197_17440
ERAF: J9537_09250(nuoF) J9537_09255
EMS: P3T75_07410
EDE: AAEO79_06075
CBK: CLL_A2000
CBT: CLH_1604 CLH_1644
CBE: Cbei_1773
CBZ: Cbs_1773
CBEI: LF65_01916 LF65_03652
CLJ: CLJU_c07040
CCB: Clocel_2588
CLS: CXIVA_00910 CXIVA_06850 CXIVA_14930 CXIVA_16350 CXIVA_21460(NuoF) CXIVA_23660 CXIVA_23670(NuoF) CXIVA_23680 CXIVA_23700(NuoE)
CLB: Clo1100_0751 Clo1100_2676 Clo1100_2677 Clo1100_2678 Clo1100_2680
CSR: Cspa_c24540 Cspa_c33070(hndD1) Cspa_c35380 Cspa_c47550(nuoF)
CPAT: CLPA_c34400(hndC)
CPAE: CPAST_c34400(hndC)
CSB: CLSA_c23760(hndD)
CAH: CAETHG_2795
CSQ: CSCA_4946
CACE: CACET_c32700 CACET_c32710 CACET_c32730 CACET_c32740 CACET_c35720(nuoG) CACET_c35740
CCK: Ccar_16070
CTAE: BGI42_08165
CFM: BJL90_01765 BJL90_01780 BJL90_01785
CDRK: B9W14_20080
CIA: BEN51_01050 BEN51_03310
CDY: F3K33_08790
CFER: D4Z93_04800
CLOS: DMR38_03370
CCAA: KQH81_00505
CNN: CNEO_2610
CGEL: psyc5s11_20550 psyc5s11_26420
CINT: HZF06_14260
CTHD: CDO33_16050 CDO33_16055 CDO33_16060 CDO33_16070
CIU: G4D55_17605
CLOM: AXY43_23505
CLOO: RCG18_02865
CALE: FDN13_01610 FDN13_01615(nuoF) FDN13_01620 FDN13_10460 FDN13_12880 FDN13_12885
CALD: PWK10_05325 PWK10_05335 PWK10_13980
CRS: FQB35_03905 FQB35_03910(nuoF) FQB35_03915 FQB35_11220 FQB35_14710
CPRF: K7H06_03105 K7H06_03110(nuoF) K7H06_03115 K7H06_03125 K7H06_03130(nuoF) K7H06_03135 K7H06_11915 K7H06_17800
CRAS: KVH43_01525 KVH43_01530(nuoF) KVH43_01535 KVH43_05375
OCW: OW730_18890
PROQ: P6M73_16520
CTH: Cthe_0338 Cthe_0340 Cthe_0341 Cthe_0342
CTX: Clo1313_1881 Clo1313_1882 Clo1313_1883 Clo1313_1885
CCL: Clocl_1309 Clocl_1311 Clocl_1312 Clocl_1313
HSC: HVS_11610(hndB1) HVS_12575(hndD2) HVS_12580(hndC2) HVS_12585(hndB2) HVS_12595(hndA2)
CCE: Ccel_2232 Ccel_2233 Ccel_2234 Ccel_2236 Ccel_2467
RHER: EHE19_005425(nuoE) EHE19_005435 EHE19_005440(nuoF) EHE19_005445
RPAY: P0092_04420 P0092_15145 P0092_15150(nuoF) P0092_15155 P0092_15165(nuoE)
CSS: Cst_c09400(nuoE) Cst_c09420 Cst_c09430(nuoF2) Cst_c09440
CSD: Clst_0900(fhbA) Clst_0902(fdx1) Clst_0903(fhbB) Clst_0904(fhbC)
FPLA: A4U99_00370 A4U99_03555 A4U99_03560 A4U99_03565
EHA: Ethha_2293
RAL: Rumal_2964 Rumal_2965
RCH: RUM_16060 RUM_16080 RUM_16090 RUM_16100
OVA: OBV_29610
SMAN: C12CBH8_13120 C12CBH8_13130 C12CBH8_13140 C12CBH8_13160
ACOL: K5I23_04445 K5I23_04450
LASA: L9O85_09690 L9O85_09700
PETR: QKW49_00175 QKW49_00180(nuoF) QKW49_00185 QKW49_16100 QKW49_20025
PALM: RBG61_01760(nuoF) RBG61_01765
OKO: Ruko_15090 Ruko_25520 Ruko_25530(nuoF) Ruko_25540
HMB: ACI0CA_13740(nuoF) ACI0CA_13745
RUK: A4V00_14230 A4V00_14235 A4V00_14240
ESR: ES1_19890 ES1_19910 ES1_19930
ESU: EUS_11280 EUS_11300 EUS_11320
CCEL: CCDG5_0742 CCDG5_0743(hndC) CCDG5_0744(hndD)
CAPR: EQM14_01110
CFEM: HCR03_13575
AMUR: ADH66_14095 ADH66_14100 ADH66_14105
AGAT: RWV98_11875
STH: STH3209
SWO: Swol_0784 Swol_1017 Swol_1701 Swol_2436
SLP: Slip_0124 Slip_0125 Slip_0543 Slip_2098
SALQ: SYNTR_0507 SYNTR_1606 SYNTR_1607
SGY: Sgly_2185 Sgly_2914
DED: DHBDCA_p1588(hymB) DHBDCA_p1589 DHBDCA_p1590(hymA) DHBDCA_p1640 DHBDCA_p874(hymC)
DEC: DCF50_p1598(hymB) DCF50_p1599 DCF50_p1600(hymA) DCF50_p1649 DCF50_p933(hymC)
DRS: DEHRE_08805 DEHRE_11740 DEHRE_11745 DEHRE_11750 DEHRE_11890 DEHRE_12025
DCA: Desca_1017 Desca_1224 Desca_1225 Desca_1997 Desca_1998
PTH: PTH_1377 PTH_1378(NuoF) PTH_2010
DRM: Dred_0463 Dred_1651 Dred_1652
DRU: Desru_0515 Desru_0516 Desru_2397 Desru_2398 Desru_3431
DFG: B0537_03245 B0537_07840 B0537_07845
DAE: Dtox_0172 Dtox_0173 Dtox_0174 Dtox_0176 Dtox_3504 Dtox_3829 Dtox_3830
DKU: Desku_0995 Desku_1528 Desku_2307 Desku_2308 Desku_2309 Desku_2311 Desku_2934
TFR: BR63_13425 BR63_13430(nuoF) BR63_13435 BR63_13440(nuoE) BR63_18510 BR63_18515 BR63_18520
FWA: DCMF_01595 DCMF_07650 DCMF_07660 DCMF_20805
PHOS: ABFY19_02270 ABFY19_07410 ABFY19_07895 ABFY19_11240
TJR: TherJR_0743 TherJR_2550 TherJR_2551 TherJR_2552
DGI: Desgi_1115 Desgi_1983 Desgi_2137
HMO: HM1_1029(nuoG)
HCV: FTV88_2333 FTV88_2334 FTV88_2507 FTV88_2509
ELM: ELI_0845 ELI_0846 ELI_0847
EMT: CPZ25_017165 CPZ25_017170 CPZ25_017175
ELIM: B2M23_11915 B2M23_11925 B2M23_11930 B2M23_11935
AWO: Awo_c26970(hydA1) Awo_c26980(hydB) Awo_c26990(hydD)
AWI: CHL1_000834 CHL1_000835(nuoF) CHL1_000836
ALKA: J0B03_01890 J0B03_02965 J0B03_03015
ACAE: HYG86_02045(nuoF) HYG86_02050 HYG86_03675 HYG86_07620
ALAC: JYE50_07305 JYE50_07315
AHC: JYE49_07300 JYE49_07310
CTHM: CFE_2039 CFE_2040 CFE_2217
IBU: IB211_00393 IB211_00394 IB211_00395
PROM: QO263_02380
BPRM: CL3_28570
BPRS: CK3_02010
CBAF: JS518_02080 JS518_02090
CCT: CC1_10620 CC1_10630 CC1_10640
CCOM: I6K69_07370
BPRO: PMF13cell1_04623(hndD_2)
BLAR: LC508_04225
BHV: BLHYD_15530 BLHYD_15540(hndD_1)
CPY: Cphy_2056 Cphy_3801 Cphy_3803 Cphy_3804 Cphy_3805
LACY: A4V08_01515 A4V08_10155 A4V08_10160 A4V08_10165
CSCI: HDCHBGLK_00083(hndD_1) HDCHBGLK_00084(hndC_1) HDCHBGLK_00085(hndB) HDCHBGLK_00087(hndA) HDCHBGLK_00500(hndD_2)
CHYL: CE91St63_25470 CE91St63_25480 CE91St63_25490 CE91St63_29810
CSH: Closa_3390 Closa_3392 Closa_3393 Closa_3394
CSO: CLS_02870
LXA: OW255_17365 OW255_17370(nuoF) OW255_17375
BPRL: CL2_24320
ARF: AR1Y2_2834
ACAC: EYQ97_04130
HSD: SD1D_2323 SD1D_2324(hndC) SD1D_2325(hndD)
LUA: D4A81_12960
EHL: EHLA_0358 EHLA_2242
ANR: Ana3638_06225 Ana3638_06230(nuoF) Ana3638_06235
ACEL: acsn021_01000 acsn021_01010 acsn021_01020 acsn021_01040
ACHT: bsdcttw_47950 bsdcttw_47960 bsdcttw_47970
EEL: EUBELI_00201
RTO: RTO_15320
CBOL: CGC65_22485 CGC65_22490 CGC65_22495 CGC65_22580
CASP: NQ535_07105 NQ535_07135 NQ535_07140(nuoF) NQ535_07145
ECLF: QMP25_09335 QMP25_38670 QMP25_38675(nuoF) QMP25_38680
SCAZ: ACI3DN_04090
AHB: bsdtb5_26960 bsdtb5_26970
CBIL: EUBC25_21330 EUBC25_21340 EUBC25_21350
HHJ: NQ487_13200 NQ487_25765 NQ487_25770(nuoF) NQ487_25775 NQ487_26355
LBW: C3V36_13275 C3V36_13280 C3V36_13285
LBX: lbkm_2368 lbkm_3446 lbkm_3447 lbkm_3448
CLE: Clole_2394 Clole_2395 Clole_2396 Clole_2397
CEW: EKH84_14585 EKH84_14590 EKH84_14595
CBAR: PATL70BA_1019(hndD) PATL70BA_1020(hndC) PATL70BA_1021 PATL70BA_2848(hndD)
VGU: HYG85_00670 HYG85_10350 HYG85_10355 HYG85_10360 HYG85_15080 HYG85_15085 HYG85_15090
VPY: HZI73_02030 HZI73_02035 HZI73_02040 HZI73_06730 HZI73_11280 HZI73_22865 HZI73_22870 HZI73_22875 HZI73_22880
MDV: C5Q96_03535 C5Q96_03540
MNL: QU661_05090 QU661_05095(nuoF)
ETM: CE91St48_32090 CE91St48_32250
EMJ: V1225_14350 V1225_14375
AHAD: FRZ06_01335 FRZ06_12025
AMT: Amet_0638 Amet_0639 Amet_0640 Amet_4100 Amet_4101 Amet_4109
GFE: Gferi_09405 Gferi_20695 Gferi_20705 Gferi_20765 Gferi_20770 Gferi_22870 Gferi_22875
CSPO: QNI18_01045 QNI18_01055 QNI18_03795
PBIF: KXZ80_11255
PSOR: RSJ16_04570 RSJ16_12970
ROC: HF520_03830
RIL: CRIB_1054
RHOM: FRIFI_1132 FRIFI_1310
PHX: KGNDJEFE_00571(hndD)
TEM: JW646_04820
TGC: L0P85_03540
TMY: TEMA_38980(rsxB_6)
TPET: TPHSE_09090(rsxB_2)
TEB: T8CH_1954(hndD) T8CH_2293(hndD) T8CH_3077(hndD)
THYR: P4S50_01025 P4S50_05740
IBR: NQ514_03810
EAC: EAL2_808p02660 EAL2_c04310(hymC)
CMIU: B1H56_03765 B1H56_04375 B1H56_04380 B1H56_04385
DAU: Daud_0109 Daud_0152 Daud_1338 Daud_1548 Daud_1923
TTE: TTE0892 TTE0893(NuoF) TTE0894(NuoG)
TEX: Teth514_2138 Teth514_2139 Teth514_2140
THX: Thet_0795 Thet_0796 Thet_0797
TPD: Teth39_1456 Teth39_1457 Teth39_1458
TIT: Thit_0828 Thit_0829 Thit_0830
TMT: Tmath_0867 Tmath_0868 Tmath_0869
TBO: Thebr_1491 Thebr_1492 Thebr_1493
TWI: Thewi_0978 Thewi_0979 Thewi_0980
TKI: TKV_c19580(hydA1)
THEZ: OEI98_000982 OEI98_000983(nuoF) OEI98_000984
ADG: Adeg_0290 Adeg_0332 Adeg_1781 Adeg_1783
TPZ: Tph_c18450
GEK: kuro4_25690
TTM: Tthe_1116 Tthe_1118 Tthe_1119 Tthe_1120
TTO: Thethe_01060 Thethe_01062 Thethe_01063 Thethe_01064
TXY: Thexy_1580 Thexy_1581 Thexy_1582 Thexy_1584
TSH: Tsac_2126 Tsac_2127 Tsac_2128 Tsac_2130
THED: SAMN05660242_2934 SAMN05660242_2935 SAMN05660242_2936
AAUT: ACETAC_10975
MAS: Mahau_1250 Mahau_1252 Mahau_1253 Mahau_1254 Mahau_1381 Mahau_1382
MTA: Moth_1717 Moth_1718
MTHO: MOTHE_c17260(hndD1) MOTHE_c17270(hndC1)
MTHZ: MOTHA_c18090(hndD1) MOTHA_c18100(hndC1)
MHUI: MHLNE_17410(hndD_2)
NCJ: MCACP_16030(hndD_1) MCACP_19160(hndD_2) MCACP_19170 MCACP_19180(hndB)
TEP: TepRe1_1888 TepRe1_1889 TepRe1_1890
TAE: TepiRe1_2033(hndD) TepiRe1_2034(hndC) TepiRe1_2035
BACG: D2962_10795(nuoE) D2962_10805 D2962_10815
TOC: Toce_0693 Toce_0695 Toce_0696 Toce_0697
NTH: Nther_0098 Nther_0099 Nther_0703
NCD: ACONDI_00300(hndD) ACONDI_02921(hndB_2)
HOR: Hore_06320 Hore_06330
HAS: Halsa_1862 Halsa_1863 Halsa_1864 Halsa_1866
HPK: Hprae_1627 Hprae_1628 Hprae_1629 Hprae_1631
HALS: D7D81_01595 D7D81_01605 D7D81_17425
IFN: GM661_14115 GM661_14135 GM661_17630 GM661_17640
AAR: Acear_0268 Acear_0269 Acear_0270 Acear_0271 Acear_0532 Acear_0982 Acear_1883 Acear_1884 Acear_2301 Acear_2302
HHL: Halha_0376 Halha_0377 Halha_2285 Halha_2286 Halha_2287 Halha_2289
AFT: BBF96_04540 BBF96_04550 BBF96_07410 BBF96_07415 BBF96_09125 BBF96_09130 BBF96_09135
KME: H0A61_01405(hndC_2) H0A61_01871(hndA_4) H0A61_01873(hndB_1) H0A61_01874(hndC_4) H0A61_01875(hndD_3) H0A61_01878(hndA_5) H0A61_01879(hndB_2) H0A61_01881(hndD_4)
HPRF: HLPR_07960 HLPR_14960
MPEC: B9O19_02155 B9O19_02156
FMA: FMG_1155
PMIC: NW74_03325 NW74_07160
PHAR: NCTC13077_00350(nqo1)
GBX: SANA_15110 SANA_22130 SANA_22140
SPOA: EQM13_17995 EQM13_18000 EQM13_18005
KPAR: JL105_09265 JL105_10660
CAZO: G3A45_06540 G3A45_06545 G3A45_11645 G3A45_11650(nuoF) G3A45_11655 G3A45_11715 G3A45_11730
SEDZ: JYG23_10935(nuoE) JYG23_10940 JYG23_10945(nuoF) JYG23_10950
SEDM: RBQ61_03360 RBQ61_03370 RBQ61_10420
VRG: OKW85_02505
VOR: VEIS_04630 VEIS_18470
MED: MELS_0888
MEG: DKB62_05660 DKB62_05665 DKB62_11300
MMAX: LCQ47_05555
SSG: Selsp_1525
SRI: SELR_26360
SELM: TAMA11512_15220
MHG: MHY_20970
MFUN: GXM21_01745 GXM21_01755
SGBI: P3F81_01335 P3F81_01345 P3F81_02580 P3F81_02600 P3F81_12770
PUF: UFO1_1386
PFT: JBW_04037 JBW_04038 JBW_04039
MANA: MAMMFC1_00410 MAMMFC1_00827(hndD_2) MAMMFC1_00828(hndC_3) MAMMFC1_00830(hndD_3) MAMMFC1_00831(hndC_4) MAMMFC1_00940(hndD_4)
STED: SPTER_13820(hndD_1) SPTER_13950(sfrA) SPTER_14070(hndB) SPTER_14080(hndC_2) SPTER_14090(hndD_3)
SSPH: SPSPH_007560(hndD_1) SPSPH_009200(hndA_2) SPSPH_009220(hndD_2) SPSPH_014020(hndD_3) SPSPH_014350(hndB) SPSPH_014370(hndD_4)
SOVA: SOV_13460(hndD_1) SOV_14580(hndB) SOV_14600(hndD_2) SOV_46430(hndD_4) SOV_46450(hndA_4)
SSID: SPSIL_016340(hndD_1) SPSIL_018690(hndD_2) SPSIL_019650(hndB) SPSIL_019670(hndD_3) SPSIL_040710(hndD_4)
SACV: SPACI_001180(hndB_1) SPACI_016200(hndD_1) SPACI_019180(hndD_2) SPACI_019420(hndB_2) SPACI_019440(hndD_3) SPACI_055740(hndD_4)
SCAO: SCACP_13010(hndD_1) SCACP_13230(hndB) SCACP_13250(hndD_3)
AFN: Acfer_1955
AIN: Acin_2259(nuoG)
PFAC: PFJ30894_00902(hndB) PFJ30894_00903(hndC) PFJ30894_00904(hndD_1)
BULL: JOS54_06760
EBM: SG0102_13030
LCG: L3BBH23_06690
SMOE: RGT18_07110
AHQ: NMU03_11435 NMU03_11445
ERB: A4V01_20385
TUR: AT726_09495 AT726_09500 AT726_09505
TSG: HLK68_09355 HLK68_09360(nuoF) HLK68_09365
TBB: J0J69_12740 J0J69_12745(nuoF) J0J69_12750
TFC: T23_05470 T23_05490
TUK: VXM77_08890 VXM77_08900
ERM: EYR00_09750 EYR00_09785 EYR00_09790 EYR00_09795
TSF: NQ543_04425 NQ543_04430 NQ543_04435
LPIL: LIP_0871
FCZ: IMF26_08180 IMF26_08190
CSC: Csac_1860 Csac_1862 Csac_1863 Csac_1864
ATE: Athe_1295 Athe_1297 Athe_1298 Athe_1299
COB: COB47_1258 COB47_1259 COB47_1260 COB47_1262
CHD: Calhy_1427 Calhy_1428 Calhy_1429 Calhy_1431
COW: Calow_1086 Calow_1088 Calow_1089 Calow_1090
CKI: Calkr_1280 Calkr_1282 Calkr_1283 Calkr_1284
CLC: Calla_0683 Calla_0685 Calla_0686 Calla_0687
CKN: Calkro_1402 Calkro_1403 Calkro_1404 Calkro_1406
CCHA: ELD05_06980 ELD05_06985(nuoF) ELD05_06990 ELD05_07000(nuoE)
CDIA: CaldiYA01_12070 CaldiYA01_12080 CaldiYA01_12090 CaldiYA01_12110
CNAG: OTJ99_001433 OTJ99_001434(nuoF) OTJ99_001435 OTJ99_001437(nuoE)
CMOR: OTK00_001330 OTK00_001331(nuoF) OTK00_001332 OTK00_001334(nuoE)
CDAN: SOJ16_001252(nuoE) SOJ16_001254 SOJ16_001255(nuoF) SOJ16_001256
MANR: MPAN_008040 MPAN_013430 MPAN_013450
XCL: G4Z02_04365 G4Z02_06970
MBJ: KQ51_00322(hndB_1) KQ51_00323(hndC_1) KQ51_00324 KQ51_00791(hndD_1) KQ51_01818(hndB_2) KQ51_01835(nuoG)
TBM: BK010_06995 BK010_07000 BK010_07005
TBZ: BK011_07465 BK011_07470 BK011_07475
OLS: Olsu_0826 Olsu_1006
TIO: INP52_07055
CGO: Corgl_0838
CAER: CSV91_04530
SHI: Shel_16530
EYY: EGYY_04050 EGYY_15690
AEQ: AEQU_2224
AHAT: ADCFC_00730
ERZ: ER308_18500
PDX: Psed_3296
PHH: AFB00_26060
TTR: Tter_1539
ATM: ANT_17790 ANT_17800 ANT_17820
ABAT: CFX1CAM_1213 CFX1CAM_1215 CFX1CAM_1216
PSUB: Pelsub_P1914 Pelsub_P1915 Pelsub_P1917
LEK: hrd7_26600
ABAO: BEQ56_02675
TAI: Taci_0147 Taci_0148 Taci_0149 Taci_0150
CPOR: BED41_00310 BED41_00320 BED41_05425
ACO: Amico_1557
AMIZ: RBH88_01835
TLI: Tlie_1466 Tlie_1619
AMO: Anamo_0024 Anamo_1679
ARAM: KAR29_00200 KAR29_00205 KAR29_00210(nuoF) KAR29_00215 KAR29_00255
APRP: KIH16_00200 KIH16_00205 KIH16_00210(nuoF) KIH16_00215 KIH16_00255
TMA: TM0011 TM0201
TMM: Tmari_0008 Tmari_0199
TMI: THEMA_03725 THEMA_04745
TMW: THMA_0007 THMA_0208
TMQ: THMB_0007 THMB_0208
TMX: THMC_0007 THMC_0208
TPT: Tpet_0912
TNP: Tnap_0642 Tnap_0831
TRQ: TRQ2_0747 TRQ2_0934
TNA: CTN_0687
THQ: T2812B_03795 T2812B_04725
THZ: CELL2_04735
THR: TRQ7_03890 TRQ7_04910
TLE: Tlet_1350 Tlet_1518 Tlet_1521
TTA: Theth_0092 Theth_1566 Theth_1569
PHY: AJ81_00105 AJ81_08385 AJ81_08400
TME: Tmel_1168 Tmel_1171 Tmel_1601
TAF: THA_1554 THA_1558 THA_1808
THP: BG95_06645 BG95_06660 BG95_08710
THER: Y592_06725 Y592_06740 Y592_08815
TFE: JYK00_00830 JYK00_08075
FNO: Fnod_0236 Fnod_0991 Fnod_0994
FPE: Ferpe_0291 Ferpe_0292 Ferpe_1116 Ferpe_1120
FIA: NA23_01740 NA23_05520(nuoF) NA23_05535
FRR: IB67_06645 IB67_06650 IB67_08860 IB67_08880
FNG: JM64_05115 JM64_05120 JM64_08415 JM64_08435
FGW: QO060_04600(nuoF) QO060_04620 QO060_08675 QO060_08680
FTHL: U0O82_03310(nuoF) U0O82_03325 U0O82_04055
OCY: OSSY52_17030 OSSY52_21290(hymB) OSSY52_21300 OSSY52_21310
PMO: Pmob_0724 Pmob_0725 Pmob_0726 Pmob_1149
MPZ: Marpi_1895 Marpi_1896 Marpi_1897
MARN: LN42_10050 LN42_10055
MAEO: JRV97_02895 JRV97_10880
DTN: DTL3_0214 DTL3_0799(hndD3)
OCS: OF820_03175 OF820_03180 OF820_12015
KOL: Kole_0172 Kole_0181 Kole_0184
KPF: IX53_02690 IX53_02705 IX53_02780
MPG: Theba_0461 Theba_0464
MINF: MESINF_2168 MESINF_2171
ASAC: ATHSA_0551 ATHSA_0552 ATHSA_0845 ATHSA_1936
FVA: FV113G1_03860(nuoF) FV113G1_03870(nuoG) FV113G1_24290 FV113G1_26580
FUL: C4N20_00705 C4N20_04455 C4N20_04460 C4N20_10420
FMO: C4N19_00165 C4N19_03610 C4N19_03615
FGO: C4N16_04400
FNF: BSQ88_02970 BSQ88_02975
FHO: H9Q81_04735
IPO: Ilyop_0625 Ilyop_0626 Ilyop_0627 Ilyop_0628 Ilyop_0635 Ilyop_0689 Ilyop_0690 Ilyop_2431
CSOM: MKD34_03080 MKD34_03085 MKD34_03090 MKD34_10650 MKD34_12420
LEO: AMK43_00690 AMK43_00695 AMK43_00700
STR: Sterm_0623 Sterm_0624 Sterm_0625 Sterm_3599 Sterm_3600 Sterm_3601
HABY: HLVA_12340 HLVA_12350 HLVA_12360 HLVA_12370
BANA: BARAN1_0488 BARAN1_0490(HoxF) BARAN1_0495
BIH: BIP78_1096 BIP78_1098 BIP78_1103
MOX: DAMO_0854
MARW: MNSC_11190
FBN: HY931_01555
PFU: PF0893 PF0894 PF1331 PF1332
PFI: PFC_03675 PFC_03680 PFC_05870 PFC_05875
PHO: PH1292(PH1292) PH1294(PH1294)
PAB: PAB0640(hydD-2) PAB0641(hydA-2) PAB1786 PAB1787
PYN: PNA2_1551 PNA2_1553 PNA2_1665 PNA2_1666
PYA: PYCH_00040 PYCH_00050 PYCH_08370 PYCH_08380
PYS: Py04_0892 Py04_0893 Py04_1129 Py04_1130
PYC: TQ32_02785 TQ32_02790 TQ32_03115 TQ32_03120
TKO: TK2069 TK2070
TON: TON_0052 TON_0053 TON_0534 TON_0535
TSI: TSIB_0284 TSIB_0285 TSIB_1522 TSIB_1523
TBA: TERMP_00069 TERMP_00070 TERMP_00536 TERMP_00537
THE: GQS_02470 GQS_02475 GQS_04985 GQS_04990
THA: TAM4_296 TAM4_701 TAM4_99
THM: CL1_0143 CL1_0144 CL1_0643 CL1_0644
TLT: OCC_03062 OCC_03067 OCC_12216 OCC_12221
THS: TES1_0166 TES1_0167
TNU: BD01_0437 BD01_0438 BD01_2067 BD01_2068
TEU: TEU_09725 TEU_09730
TGY: X802_03245 X802_03250 X802_07560 X802_07565
THV: ADU37_CDS02170 ADU37_CDS02180 ADU37_CDS16280 ADU37_CDS16290
TCH: CHITON_0949 CHITON_0950 CHITON_1019 CHITON_1020
TPEP: A0127_05275 A0127_05280 A0127_07135 A0127_07140
TPIE: A7C91_06185 A7C91_06190 A7C91_08725 A7C91_08730
TGG: A3K92_08480 A3K92_08485
TCE: A3L02_00965 A3L02_00970 A3L02_02385 A3L02_02390
TBS: A3L01_00920 A3L01_00925 A3L01_03415 A3L01_03420
THH: CDI07_00920 CDI07_00925 CDI07_03355 CDI07_03360
TSL: A3L11_04675 A3L11_04680 A3L11_07375 A3L11_07380
TTD: A3L14_02375 A3L14_02380 A3L14_05100 A3L14_05105
TPRF: A3L09_05685 A3L09_05690 A3L09_05740 A3L09_05745
TRL: A3L10_03150 A3L10_03155 A3L10_05635 A3L10_05640
TPAF: A3L08_06480 A3L08_06485
THY: A3L12_05480 A3L12_05485
TIC: FH039_02775 FH039_02780 FH039_05970 FH039_05975
TCQ: TIRI35C_0406(shyA) TIRI35C_0407(shyD) TIRI35C_0918(hydA) TIRI35C_0919(hydD)
THEM: FPV09_03375 FPV09_03380 FPV09_06575 FPV09_06580
THEI: K1720_00335 K1720_00340 K1720_04545 K1720_04550
TAGG: NF865_01275(hydA) NF865_01280(hydD)
PPAC: PAP_01490 PAP_01495 PAP_03250 PAP_03255
MCJ: MCON_3103(nuoF)
HUT: Huta_2099
HTI: HTIA_1871
HARC: HARCEL1_01230
KCR: Kcr_0321 Kcr_0322
MVJ: ACO0C9_08320
BARB: AOA66_1503(shyD) AOA66_1504(hydA)
 » show all
Reference
1  [PMID:9703971]
  Authors
de Luca G, de Philip P, Rousset M, Belaich JP, Dermoun Z
  Title
The NADP-reducing hydrogenase of Desulfovibrio fructosovorans: evidence for a native complex with hydrogen-dependent methyl-viologen-reducing activity.
  Journal
Biochem Biophys Res Commun 248:591-6 (1998)
DOI:10.1006/bbrc.1998.9022
  Sequence
[ag:AAA87054 AAA87055 AAA87056 AAA87057]
Reference
2  [PMID:2538471]
  Authors
Bryant FO, Adams MW
  Title
Characterization of hydrogenase from the hyperthermophilic archaebacterium, Pyrococcus furiosus.
  Journal
J Biol Chem 264:5070-9 (1989)
DOI:10.1016/S0021-9258(18)83701-2
  Sequence
[pfu:PF0894 PF0893]
Reference
3  [PMID:8389482]
  Authors
Ma K, Schicho RN, Kelly RM, Adams MW
  Title
Hydrogenase of the hyperthermophile Pyrococcus furiosus is an elemental sulfur reductase or sulfhydrogenase: evidence for a sulfur-reducing hydrogenase ancestor.
  Journal
Proc Natl Acad Sci U S A 90:5341-4 (1993)
DOI:10.1073/pnas.90.11.5341
Reference
4
  Authors
Ma K, Zhou ZH, Adams MW.
  Title
Hydrogen production from pyruvate by enzymes purified from the hyperthermophilic archaeon, Pyrococcus furiosus: A key role for NADPH.
  Journal
FEMS Microbiol Lett 122:245-250 (1994)
Reference
5  [PMID:18156274]
  Authors
van Haaster DJ, Silva PJ, Hagedoorn PL, Jongejan JA, Hagen WR
  Title
Reinvestigation of the steady-state kinetics and physiological function of the soluble NiFe-hydrogenase I of Pyrococcus furiosus.
  Journal
J Bacteriol 190:1584-7 (2008)
DOI:10.1128/JB.01562-07
Other DBs
ExplorEnz - The Enzyme Database: 1.12.1.3
IUBMB Enzyme Nomenclature: 1.12.1.3
ExPASy - ENZYME nomenclature database: 1.12.1.3
BRENDA, the Enzyme Database: 1.12.1.3
CAS: 9027-05-8
LinkDB

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