KEGG   ENZYME: 1.12.1.3
Entry
EC 1.12.1.3                 Enzyme                                 
Name
hydrogen dehydrogenase (NADP+);
NADP+-linked hydrogenase;
NADP+-reducing hydrogenase;
hydrogenase (ambiguous);
hydrogenase I (ambiguous)
Class
Oxidoreductases;
Acting on hydrogen as donor;
With NAD+ or NADP+ as acceptor
Sysname
hydrogen:NADP+ oxidoreductase
Reaction(IUBMB)
H2 + NADP+ = H+ + NADPH [RN:R07181]
Reaction(KEGG)
R07181
Substrate
H2 [CPD:C00282];
NADP+ [CPD:C00006]
Product
H+ [CPD:C00080];
NADPH [CPD:C00005]
Comment
The protein from the bacterium Desulfovibrio fructosovorans is an iron-sulfur protein that exclusively functions as a hydrogen dehydrogenase [1], while the enzyme from the archaeon Pyrococcus furiosus is a nickel, iron, iron-sulfur protein, that is part of a heterotetrameric complex where the alpha and delta subunits function as a hydrogenase while the beta and gamma subunits function as sulfur reductase (EC 1.12.98.4, sulfhydrogenase). Different from EC 1.12.1.5, hydrogen dehydrogenase [NAD(P)+].
History
EC 1.12.1.3 created 2002, modified 2013
Orthology
K17992  NADP-reducing hydrogenase subunit HndB
K17993  sulfhydrogenase subunit alpha
K17994  sulfhydrogenase subunit delta
K18330  NADP-reducing hydrogenase subunit HndA
K18331  NADP-reducing hydrogenase subunit HndC
K18332  NADP-reducing hydrogenase subunit HndD
Genes
AVLAvCA_04400(hoxH)
AVDAvCA6_04400(hoxH)
ACXAchr_4360(hoxY) Achr_4370(hoxH)
MSQBKP64_00955 BKP64_00960
MARAD0851_07215 D0851_07220
PAEWKIH87_09725 KIH87_09730
MICCAUP74_02543(hoxH) AUP74_02544(hoxY)
MIIBTJ40_11460 BTJ40_11465
MICTFIU95_09940(hoxH) FIU95_09945(hoxY)
MHYDGTQ55_08910 GTQ55_08915
ALGAQULUS_13030(hoxH) AQULUS_13040(hoxY)
ASIPAQUSIP_08270(hoxY) AQUSIP_08280(hoxH)
LPNlpg2467(hydA) lpg2468
LPHLPV_2792 LPV_2793
LPOLPO_2656 LPO_2657
LPULPE509_00593 LPE509_00594
LPMLP6_2497(hydA) LP6_2498
LPFlpl2387 lpl2388
LPPlpp2532 lpp2533
LPCLPC_2010 LPC_2011(hydA)
LPAlpa_03596 lpa_03597
LPElp12_2459 lp12_2460
LLOLLO_2450 LLO_2451
LOKLoa_02480 Loa_02481
LSHCAB17_17515 CAB17_17520
LIBE4T55_10920 E4T55_10925
LGTE4T54_10400 E4T54_10405
LJRNCTC11533_01742(hoxH) NCTC11533_01743(hoxY)
LCJNCTC11976_02959(hoxY) NCTC11976_02962(hoxH_2)
LSSNCTC12082_00642(hoxY) NCTC12082_00643(hoxH)
TMCLMI_1438 LMI_1439
MMAIsS8_1969 sS8_1970
FPHFphi_0818 Fphi_0819
FPTBZ13_1195 BZ13_1196
FPIBF30_1033 BF30_1034
FPMLA56_1342 LA56_1343
FPXKU46_521 KU46_522
FPZLA55_2065 LA55_2066
FPJLA02_420 LA02_421
FRTF7308_1952 F7308_1953
FNAOOM_1816
FNLM973_00225
FRFLO80_06090 LO80_06095
FHACDV26_00130 CDV26_00135
FRXF7310_10160 F7310_10165
FRCKX01_345 KX01_346
FMIF0R74_08320 F0R74_08325
FSRKQR59_09315 KQR59_09320
TLOJ9253_17480 J9253_17485
NHLNhal_1537 Nhal_1538
NWRE3U44_15705 E3U44_15710
ALVAlvin_0807 Alvin_0808
TEETel_04925 Tel_04930
THIMKFB96_22620 KFB96_22625
HHCM911_03920 M911_03925
EBSECTOBSL9_1957 ECTOBSL9_1958
TGRTgr7_1137 Tgr7_1138
TNITVNIR_2169 TVNIR_2170(vhuG_[H])
TTITHITH_06475 THITH_06480
TVRTVD_13255 TVD_13260
APRSBI364_04840 BI364_04845
HAZA9404_02270 A9404_02275
TTCFOKN1_2277 FOKN1_2278
HSIBOX17_10620 BOX17_10625
HBEBEI_0366 BEI_0367
MGEOCFI10_06200 CFI10_06205
MSECLN244_04715 LN244_04720
NCUF0U83_02275 F0U83_02280
RFOREIFOR_00615 REIFOR_00616
OCEGU3_11735 GU3_11740
ZDFAN401_10020 AN401_10025
GBIPG2T_03070 PG2T_03075
SLIMSCL_2124 SCL_2125
SVASVA_2158 SVA_2159
REVHUE57_13155 HUE57_13160
ENMEBS_0040 EBS_0041
NBACUN60_10630 CUN60_10635
BUZAYM40_36800 AYM40_36805
PARBCJU94_13625 CJU94_13630
PVEUC34_24700
PTXABW99_09705 ABW99_09710
BHOD560_2878
BHMD558_2856
NOKFAY22_03480 FAY22_03485
BBAGE1O_11220 E1O_11230
TBDTbd_1263
GEBGM18_1856 GM18_1857 GM18_1858 GM18_1859
GPIGPICK_09395
GEOGeob_0218(bamH-1) Geob_0234(bamH-2)
GBNGEOBRER4_17890 GEOBRER4_17900
GSBGSUB_14255 GSUB_14260
GERKP004_08740 KP004_08745
GSUBKP001_06415 KP001_06420
GNTKP003_08265 KP003_08270
PCAPcar_1602(hndA-3) Pcar_1603(hndB-3) Pcar_1604(hndC-3) Pcar_1605(hndD-3) Pcar_1633(hndD-2) Pcar_1634(hndC-2) Pcar_1635(hndB-2) Pcar_1636(hndA-2) Pcar_1844(hndC-1) Pcar_1845(hndB-1) Pcar_1846(hndA-1) Pcar_2708(hndC-5)
PACEA6070_04705 A6070_07085 A6070_07090 A6070_07095 A6070_07100 A6070_07285 A6070_07950 A6070_07955 A6070_07960 A6070_07965 A6070_09010
PEFA7E78_02215 A7E78_02220 A7E78_02225 A7E78_02230 A7E78_06775 A7E78_06780
PPDPpro_3516 Ppro_3517 Ppro_3518
DESDSOUD_2750 DSOUD_2751 DSOUD_3307 DSOUD_3308
DEUDBW_2713 DBW_2714 DBW_3345 DBW_3346
DVEDESUT3_12230 DESUT3_12240
DFLDFE_3279 DFE_3280
DSDGD606_13030 GD606_13035
DMADMR_02450 DMR_02460 DMR_02470(nuoF) DMR_02480
DCBC3Y92_00825 C3Y92_00830 C3Y92_00835 C3Y92_00840
DAFDesaf_2138 Desaf_2139
DSXGD604_00285 GD604_00290
DSFUWK_01340 UWK_01341
DMLDmul_28600(nuoF3) Dmul_34230(morB)
DALDalk_2271
DATHRM2_16520
DTOTOL2_C03720(bamH1) TOL2_C28870 TOL2_C28900 TOL2_C41380(bamH2) TOL2_C43510(bamH3)
DOVDSCO28_20310 DSCO28_66020
DALKDSCA_31590 DSCA_31610 DSCA_35390 DSCA_35400
DLIdnl_05790 dnl_18600 dnl_18610(nuoF) dnl_49300
DMMdnm_034430 dnm_042000(nuoF1) dnm_042010 dnm_042020
DEKDSLASN_10770 DSLASN_26630 DSLASN_26640 DSLASN_26650 DSLASN_26660
CFUSCYFUS_000606 CYFUS_000607
SCLsce4575(hoxH)
SCUSCE1572_36515 SCE1572_36520
LLUAKJ09_02923 AKJ09_02924
SATSYN_00152 SYN_02221 SYN_02222
DAODesac_1693 Desac_1694
DTIDesti_1918 Desti_2752 Desti_2753
DAXFDQ92_01160(nuoF)
DBRDeba_0481 Deba_0785 Deba_1519 Deba_1520 Deba_2120
PCAYFRD00_01940 FRD00_01945
OCAOCAR_5286
OCGOCA5_c26870
OCOOCA4_c26860
BIDBind_0506 Bind_0507
MSCBN69_0845 BN69_0846
MROSEHO51_04985 EHO51_04990
MPARF7D14_01855 F7D14_01860
MTWCQW49_20325 CQW49_20330
LABPFJ695_24195
RRFF11_01565
MGYMGMSRv2__1308 MGMSRv2__1309
MGRYMSR1_09580(hoxH) MSR1_09590(hoxY)
DEXHWD60_06920 HWD60_06925
MAGQMGMAQ_3148 MGMAQ_3149
MGMMmc1_0883
AFRAFE_0937(hoxH) AFE_0938(hoxY)
AFELferr_1055 Lferr_1056
AFIAcife_1820 Acife_1821
AFJAFERRID_21540 AFERRID_21550
PAEQR50912_06580 R50912_06585
PAEAR70723_15795 R70723_15800
PAEER70331_15235 R70331_15240
PBACHUB98_24435
PTJJRJ22_12795(nuoF) JRJ22_12800
LRNCMV25_02440 CMV25_02445
EGVEGCR1_07010 EGCR1_07015
EAVEH197_17435(nuoF) EH197_17440
ERAFJ9537_09250(nuoF) J9537_09255
CBKCLL_A2000
CBTCLH_1604 CLH_1644
CBECbei_1773
CBZCbs_1773
CBEILF65_01916 LF65_03652
CLJCLJU_c07040
CCBClocel_2588
CLSCXIVA_00910 CXIVA_06850 CXIVA_14930 CXIVA_16350 CXIVA_21460(NuoF) CXIVA_23660 CXIVA_23670(NuoF) CXIVA_23680 CXIVA_23700(NuoE)
CLBClo1100_0751 Clo1100_2676 Clo1100_2677 Clo1100_2678 Clo1100_2680
CSRCspa_c24540 Cspa_c33070(hndD1) Cspa_c35380 Cspa_c47550(nuoF)
CPATCLPA_c34400(hndC)
CPAECPAST_c34400(hndC)
CSBCLSA_c23760(hndD)
CAHCAETHG_2795
CSQCSCA_4946
CACECACET_c32700 CACET_c32710 CACET_c32730 CACET_c32740 CACET_c35720(nuoG) CACET_c35740
CCKCcar_16070
CTAEBGI42_08165
CFMBJL90_01765 BJL90_01780 BJL90_01785
CDRKB9W14_20080
CIABEN51_01050 BEN51_03310
CDYF3K33_08790
CFERD4Z93_04800
CLOSDMR38_03370
CCAAKQH81_00505
AMTAmet_0638 Amet_0639 Amet_0640 Amet_4100 Amet_4101 Amet_4109
GFEGferi_09405 Gferi_20695 Gferi_20705 Gferi_20765 Gferi_20770 Gferi_22870 Gferi_22875
CALEFDN13_01610 FDN13_01615(nuoF) FDN13_01620 FDN13_10460 FDN13_12880 FDN13_12885
CRSFQB35_03905 FQB35_03910(nuoF) FQB35_03915 FQB35_11220 FQB35_14710
CPRFK7H06_03105 K7H06_03110(nuoF) K7H06_03115 K7H06_03125 K7H06_03130(nuoF) K7H06_03135 K7H06_11915 K7H06_17800
PBIFKXZ80_11255
CAZOG3A45_06540 G3A45_06545 G3A45_11645 G3A45_11650(nuoF) G3A45_11655 G3A45_11715 G3A45_11730
CTHCthe_0338 Cthe_0340 Cthe_0341 Cthe_0342
CTXClo1313_1881 Clo1313_1882 Clo1313_1883 Clo1313_1885
CCLClocl_1309 Clocl_1311 Clocl_1312 Clocl_1313
HSCHVS_11610(hndB1) HVS_12575(hndD2) HVS_12580(hndC2) HVS_12585(hndB2) HVS_12595(hndA2)
RUKA4V00_14230 A4V00_14235 A4V00_14240
CCECcel_2232 Ccel_2233 Ccel_2234 Ccel_2236 Ccel_2467
RHEREHE19_005425(nuoE) EHE19_005435 EHE19_005440(nuoF) EHE19_005445
CSSCst_c09400(nuoE) Cst_c09420 Cst_c09430(nuoF2) Cst_c09440
CSDClst_0900(fhbA) Clst_0902(fdx1) Clst_0903(fhbB) Clst_0904(fhbC)
CTHDCDO33_16050 CDO33_16055 CDO33_16060 CDO33_16070
ESRES1_19890 ES1_19910 ES1_19930
ESUEUS_11280 EUS_11300 EUS_11320
CCELCCDG5_0742 CCDG5_0743(hndC) CCDG5_0744(hndD)
FPLAA4U99_00370 A4U99_03555 A4U99_03560 A4U99_03565
EHAEthha_2293
RALRumal_2964 Rumal_2965
RCHRUM_16060 RUM_16080 RUM_16090 RUM_16100
CAPREQM14_01110
OVAOBV_29610
SMANC12CBH8_13120 C12CBH8_13130 C12CBH8_13140 C12CBH8_13160
CFEMHCR03_13575
ACOLK5I23_04445
CLEClole_2394 Clole_2395 Clole_2396 Clole_2397
CEWEKH84_14585 EKH84_14590 EKH84_14595
CCTCC1_10620 CC1_10630 CC1_10640
CCOMI6K69_07370
BPROPMF13cell1_04623(hndD_2)
CPYCphy_2056 Cphy_3801 Cphy_3803 Cphy_3804 Cphy_3805
LACYA4V08_01515 A4V08_10155 A4V08_10160 A4V08_10165
CSCIHDCHBGLK_00083(hndD_1) HDCHBGLK_00084(hndC_1) HDCHBGLK_00085(hndB) HDCHBGLK_00087(hndA) HDCHBGLK_00500(hndD_2)
CSHClosa_3390 Closa_3392 Closa_3393 Closa_3394
CSOCLS_02870
BPRLCL2_24320
ARFAR1Y2_2834
ACACEYQ97_04130
HSDSD1D_2323 SD1D_2324(hndC) SD1D_2325(hndD)
LUAD4A81_12960
EHLEHLA_0358 EHLA_2242
ANRAna3638_06225 Ana3638_06230(nuoF) Ana3638_06235
ACELacsn021_01000 acsn021_01010 acsn021_01020 acsn021_01040
ACHTbsdcttw_47950 bsdcttw_47960 bsdcttw_47970
EELEUBELI_00201
RTORTO_15320
CBOLCGC65_22485 CGC65_22490 CGC65_22495 CGC65_22580
DLOK5I24_14130
LBWC3V36_13275 C3V36_13280 C3V36_13285
EACEAL2_808p02660 EAL2_c04310(hymC)
PSORRSJ16_04570 RSJ16_12970
ROCHF520_03830
PHXKGNDJEFE_00571(hndD)
TEMJW646_04820
TEBT8CH_1954(hndD) T8CH_2293(hndD) T8CH_3077(hndD)
SWOSwol_0784 Swol_1701 Swol_2436
SLPSlip_0124 Slip_0543 Slip_2098
SALQSYNTR_0507 SYNTR_1606 SYNTR_1607
SGYSgly_2185 Sgly_2914
DEDDHBDCA_p1588(hymB) DHBDCA_p1589 DHBDCA_p1590(hymA) DHBDCA_p1640 DHBDCA_p874(hymC)
DECDCF50_p1598(hymB) DCF50_p1599 DCF50_p1600(hymA) DCF50_p1649 DCF50_p933(hymC)
DRSDEHRE_08805 DEHRE_11740 DEHRE_11745 DEHRE_11750 DEHRE_11890 DEHRE_12025
DCADesca_1017 Desca_1224 Desca_1225 Desca_1997 Desca_1998
PTHPTH_1377 PTH_1378(NuoF) PTH_2010
DRMDred_0463 Dred_1651
DRUDesru_0515 Desru_0516 Desru_2397 Desru_2398 Desru_3431
DFGB0537_03245 B0537_07840 B0537_07845
DAEDtox_0172 Dtox_0173 Dtox_0174 Dtox_0176 Dtox_3504 Dtox_3829 Dtox_3830
DKUDesku_0995 Desku_1528 Desku_2307 Desku_2308 Desku_2309 Desku_2311
DAUDaud_0109 Daud_0152 Daud_1338 Daud_1548 Daud_1923
TFRBR63_13425 BR63_13430(nuoF) BR63_13435 BR63_13440(nuoE) BR63_18510 BR63_18515 BR63_18520
FWADCMF_01595 DCMF_07650 DCMF_07660 DCMF_07665 DCMF_20805
TJRTherJR_0743 TherJR_2550 TherJR_2551 TherJR_2552
DGIDesgi_1115 Desgi_1983 Desgi_2137
HMOHM1_1029(nuoG)
HCVFTV88_2333 FTV88_2334 FTV88_2507 FTV88_2509
ELMELI_0845 ELI_0846 ELI_0847
EMTCPZ25_017165 CPZ25_017170 CPZ25_017175
ELIMB2M23_11915 B2M23_11925 B2M23_11930 B2M23_11935
AWOAwo_c26970(hydA1) Awo_c26980(hydB) Awo_c26990(hydD)
ALKAJ0B03_01890 J0B03_02965 J0B03_03015
CTHMCFE_2039 CFE_2040 CFE_2217
CMIUB1H56_03765 B1H56_04375 B1H56_04380 B1H56_04385
IBUIB211_00393 IB211_00394 IB211_00395
CBARPATL70BA_1019(hndD) PATL70BA_1020(hndC) PATL70BA_1021 PATL70BA_2848(hndD)
VGUHYG85_00670 HYG85_10350 HYG85_10355 HYG85_10360 HYG85_15080 HYG85_15085 HYG85_15090
VPYHZI73_02030 HZI73_02035 HZI73_02040 HZI73_06730 HZI73_11280 HZI73_20445 HZI73_22865 HZI73_22870 HZI73_22875 HZI73_22880
ACAEHYG86_02045(nuoF) HYG86_02050 HYG86_03675 HYG86_07620
LASAL9O85_09690 L9O85_09700
MDVC5Q96_03535 C5Q96_03540
ETMCE91St48_32250
BPRMCL3_28570
BPRSCK3_02010
TTETTE0892 TTE0893(NuoF) TTE0894(NuoG)
TEXTeth514_2138 Teth514_2139 Teth514_2140
THXThet_0795 Thet_0796 Thet_0797
TPDTeth39_1456 Teth39_1457 Teth39_1458
TITThit_0828 Thit_0829 Thit_0830
TMTTmath_0867 Tmath_0868 Tmath_0869
TBOThebr_1491 Thebr_1492 Thebr_1493
TWIThewi_0978 Thewi_0979 Thewi_0980
TKITKV_c19580(hydA1)
MTAMoth_1717 Moth_1718
MTHOMOTHE_c17260(hndD1) MOTHE_c17270(hndC1)
MTHZMOTHA_c18090(hndD1) MOTHA_c18100(hndC1)
ADGAdeg_0290 Adeg_0332
TPZTph_c18450 Tph_c26910 Tph_c26920
GEKkuro4_25690
CSCCsac_1860 Csac_1862 Csac_1863 Csac_1864
ATEAthe_1295 Athe_1297 Athe_1298 Athe_1299
COBCOB47_1258 COB47_1259 COB47_1260 COB47_1262
CHDCalhy_1427 Calhy_1428 Calhy_1429 Calhy_1431
COWCalow_1086 Calow_1088 Calow_1089 Calow_1090
CKICalkr_1280 Calkr_1282 Calkr_1283 Calkr_1284
CLCCalla_0683 Calla_0685 Calla_0686 Calla_0687
CKNCalkro_1402 Calkro_1403 Calkro_1404 Calkro_1406
CCHAELD05_06980 ELD05_06985(nuoF) ELD05_06990 ELD05_07000(nuoE)
CDIACaldiYA01_12070
TTMTthe_1116 Tthe_1118 Tthe_1119 Tthe_1120
TTOThethe_01060 Thethe_01062 Thethe_01063 Thethe_01064
TXYThexy_1580 Thexy_1581 Thexy_1582 Thexy_1584
TSHTsac_2126 Tsac_2127 Tsac_2128 Tsac_2130
TACITDSAC_1040
MASMahau_1250 Mahau_1252 Mahau_1253 Mahau_1254 Mahau_1381 Mahau_1382
TEPTepRe1_1888 TepRe1_1889 TepRe1_1890
TAETepiRe1_2033(hndD) TepiRe1_2034(hndC) TepiRe1_2035
TOCToce_0693 Toce_0695 Toce_0696 Toce_0697
NTHNther_0098 Nther_0099 Nther_0703
NCDACONDI_00300(hndD) ACONDI_02921(hndB_2)
HORHore_06320
HASHalsa_1862 Halsa_1863 Halsa_1864 Halsa_1866
HPKHprae_1627 Hprae_1628 Hprae_1629 Hprae_1631
HALSD7D81_01595 D7D81_01605 D7D81_17425
IFNGM661_14115 GM661_14135 GM661_17630 GM661_17640
AARAcear_0268 Acear_0269 Acear_0270 Acear_0271 Acear_0532 Acear_0982 Acear_1883 Acear_1884 Acear_2301 Acear_2302
HHLHalha_0376 Halha_0377 Halha_2285 Halha_2286 Halha_2287 Halha_2289
AFTBBF96_04540 BBF96_04550 BBF96_07410 BBF96_07415 BBF96_09125 BBF96_09130 BBF96_09135
KMEH0A61_01405(hndC_2) H0A61_01871(hndA_4) H0A61_01873(hndB_1) H0A61_01874(hndC_4) H0A61_01875(hndD_3) H0A61_01878(hndA_5) H0A61_01879(hndB_2) H0A61_01881(hndD_4)
FMAFMG_1155
PMICNW74_03325 NW74_07160
PHARNCTC13077_00350(nqo1)
SPOAEQM13_17995 EQM13_18000 EQM13_18005
KPARJL105_09265 JL105_10660
SEDZJYG23_10935(nuoE) JYG23_10940 JYG23_10945(nuoF) JYG23_10950
MEDMELS_0888
MEGDKB62_05660 DKB62_05665 DKB62_11300
MMAXLCQ47_05555
SSGSelsp_1525
SRISELR_26360
MHGMHY_20970
MFUNGXM21_01745 GXM21_01755
PUFUFO1_1386
PFTJBW_04037 JBW_04038 JBW_04039
MANAMAMMFC1_00410 MAMMFC1_00827(hndD_2) MAMMFC1_00828(hndC_3) MAMMFC1_00830(hndD_3) MAMMFC1_00831(hndC_4) MAMMFC1_00940(hndD_4)
STEDSPTER_13820(hndD_1) SPTER_13950(sfrA) SPTER_14070(hndB) SPTER_14080(hndC_2) SPTER_14090(hndD_3)
AFNAcfer_1955
AINAcin_2259(nuoG)
PFACPFJ30894_00902(hndB) PFJ30894_00903(hndC) PFJ30894_00904(hndD_1)
CIUG4D55_17605
ERMEYR00_09750 EYR00_09785 EYR00_09790 EYR00_09795
BULLJOS54_06760
EBMSG0102_13030
LCGL3BBH23_06690
ERBA4V01_20385
TURAT726_09495 AT726_09500 AT726_09505
TSGHLK68_09355 HLK68_09360(nuoF) HLK68_09365
LPILLIP_0582 LIP_0583 LIP_0871
MANRMPAN_008040 MPAN_013430 MPAN_013450
MBJKQ51_00322(hndB_1) KQ51_00323(hndC_1) KQ51_00324 KQ51_00791(hndD_1) KQ51_01818(hndB_2) KQ51_01835(nuoG)
TBMBK010_06995 BK010_07000 BK010_07005
TBZBK011_07465 BK011_07470 BK011_07475
MMANMMAN_14450 MMAN_14460
MMCMmcs_3416 Mmcs_3417
MKMMkms_3479 Mkms_3480
MJLMjls_3427 Mjls_3428
MMIMMAR_3497 MMAR_3498
MMAEMMARE11_34090 MMARE11_34100
MLIMULP_03750
MKNMKAN_04225 MKAN_04230
MYEAB431_12170 AB431_12175
MHADB586_16665 B586_16670
MSHGMSG_02854 MSG_02855
MSTOMSTO_04520 MSTO_04530
MSAKMSAS_49680 MSAS_49690
MNVMNVI_35470 MNVI_35480
MPAGC0J29_14650 C0J29_14655
MGORH0P51_17800 H0P51_17805
MBAIMB901379_03108(hoxH) MB901379_03109(hoxY)
MSEOMSEO_00840 MSEO_00850
MPSEMPSD_35740 MPSD_35750
MHEKJMUB5695_01550(hoxH) JMUB5695_01551
MLJMLAC_23590 MLAC_23600
MBRDMBRA_29200
MSHJMSHI_09600 MSHI_09610
MDFK0O62_06400
MHERK3U94_12980 K3U94_12985
MPAEK0O64_11895
MSPGF6B93_12825 F6B93_12830
MOTLTS72_06950 LTS72_06955
MSMMSMEG_3928
MSGMSMEI_3838
MSBLJ00_19525 LJ00_19530
MSNLI99_19530 LI99_19535
MSHLI98_19535 LI98_19540
MCBMycch_1699
MLLB1R94_11315 B1R94_11320
MTHN4412656_03554(hoxY) 4412656_03555(hoxH)
MDUMDUV_51500 MDUV_51510
MAICMAIC_21360 MAIC_21370
MPSCMPSYJ_48130 MPSYJ_48140
MANYMANY_17730 MANY_17740
CPEGCPELA_10915
NSRNS506_04373(hydA) NS506_04374(mvhG)
NAHF5544_17320 F5544_17325
NTCKHQ06_22645 KHQ06_22650
NGPLTT66_32155
RERRER_34040
REQREQ_15170
RAVAAT18_20765 AAT18_20770
RHWBFN03_07920 BFN03_07925
SCBSCAB_10361
SHYSHJG_8771 SHJG_8772
SHOSHJGH_8527 SHJGH_8528
SRCM271_48220 M271_48225
SMALSMALA_7420 SMALA_7421
SSOII1A49_40860 I1A49_40865
SDVBN159_8137 BN159_8138
SXISXIM_54300 SXIM_54310
STRMM444_33590 M444_33595
SCXAS200_40165 AS200_40170
SRWTUE45_pSRc_0046(hoxH) TUE45_pSRc_0047(hoxY)
SPLULK06_000325 LK06_000330
SAUOBV401_40720 BV401_40725
SGVB1H19_03575 B1H19_03580
SLAUSLA_6981
SALFSMD44_08103 SMD44_08104
SALJSMD11_1043 SMD11_1044
STROSTRMOE7_01900 STRMOE7_01905
SFKKY5_7224 KY5_7225
SGEDWG14_00278(hoxY) DWG14_00279(hoxH)
SCYAEJ357_43835 EJ357_43840
SNQCP978_06415 CP978_06420
STIRDDW44_00725 DDW44_00730
SKACP970_03590 CP970_03595
SGZC0216_13070 C0216_13075
SVRCP971_32660 CP971_32665
SAQUEJC51_04405 EJC51_04410
SRIMCP984_01485 CP984_01490
SPHVF9278_19940
SFUGCNQ36_00175 CNQ36_00180
SCHFIPT68_01195 IPT68_01200
SFEUIM697_26300 IM697_26305
SMOBJ7W19_00255 J7W19_00260
SROIIAG44_01410 IAG44_01415
ACTWF7P10_09095 F7P10_09100
SROSros_4826
NOABKM31_18850 BKM31_18855
NOWGBF35_15985 GBF35_15990
NCXNocox_21175(hoxH)
TBITbis_1858
FRAFrancci3_4496 Francci3_4497
ACEAcel_1018 Acel_1019
PDXPsed_3296
PHHAFB00_26060
KALKALB_4152 KALB_4157
PSUUPsuf_068760 Psuf_068770
ATLAthai_08880 Athai_08890
DVCDvina_37845
SNASnas_3473 Snas_3474
RUBGBA63_20400 GBA63_20405
SHIShel_16530
ELEElen_1255 Elen_1256
EYYEGYY_04050 EGYY_12130 EGYY_12140 EGYY_15690
EGDGS424_006590 GS424_006595
GPAGPA_23180
AEQAEQU_0878 AEQU_0879 AEQU_2224
AHATADCFC_00730 ADCFC_14510 ADCFC_14520
OLSOlsu_0826 Olsu_1006
TIOINP52_07055
CGOCorgl_0838
CAERCSV91_04530
ERZER308_18500
LBOLBWT_7400 LBWT_7410
CYNCyan7425_2660 Cyan7425_2661
DLYDehly_0928 Dehly_0929
DEWDGWBC_1203 DGWBC_1204
DFODform_00601 Dform_00602
ATMANT_17790 ANT_17800 ANT_17820
ABATCFX1CAM_1213 CFX1CAM_1215 CFX1CAM_1216
PSUBPelsub_P1914 Pelsub_P1915 Pelsub_P1917
ABAOBEQ56_02675
CAPCLDAP_19260
THUGKNN16_04355 KNN16_04360
TTRTter_1539
OTEOter_1545
MINMinf_2390(frhG) Minf_2391(frhA)
MKCkam1_1223 kam1_2094 kam1_2096
VBSEGM51_01930(nuoF) EGM51_01935
LCREPla8534_67850(hoxY) Pla8534_67860(hoxH)
AAGGETAA8_22830(hoxY) ETAA8_22850
TTFTHTE_2881 THTE_3843
FMRFuma_01323(hoxH) Fuma_01324(hoxY)
GMRGmarT_18740(hoxY) GmarT_18750(hoxH)
GIMF1728_26570 F1728_26575
GPNPan110_37740(hoxH) Pan110_37750(hoxY)
MRIMal4_24330(hoxH) Mal4_24340(hoxY)
KSTKSMBR1_0596(nuoF_1) KSMBR1_1330(nuoF_2) KSMBR1_3673(hoxY) KSMBR1_3674(hoxH)
BROCIPI25_00220(nuoE) IPI25_07695(nuoF)
PBUL21SP3_00034(hndD_1) L21SP3_00309(hndD_2) L21SP3_00310(hndC_3)
PBPSTSP1_00009(hndD_1) STSP1_00010(hndC_1) STSP1_01250(hndD_2)
PBASSMSP2_01580(hndB) SMSP2_01581(hndC_2) SMSP2_01582(hndD_2) SMSP2_01657(hndD_3)
ALUSSTSP2_01432(hndB) STSP2_01433(hndC) STSP2_01434(hndD) STSP2_01452(hoxH) STSP2_01453(hoxY)
VBLL21SP4_00378 L21SP4_00379 L21SP4_00380 L21SP4_01302(hndD_2)
TAERGT409_10650 GT409_10655 GT409_10660 GT409_14280 GT409_14290
VAIBU251_02010 BU251_02015 BU251_02020 BU251_07790 BU251_07795
TBETrebr_0332 Trebr_0333
TAZTREAZ_3248 TREAZ_3249
TPITREPR_3595
TPEDTPE_0917 TPE_2309
SCDSpica_2775
TPKJO40_11355
TRZGWP43_12150
TRCDYE49_00610 DYE49_00615 DYE49_00620
SSMSpirs_0474 Spirs_3688 Spirs_3689
STASTHERM_c06260 STHERM_c13740 STHERM_c13750 STHERM_c13760
STQSpith_1507 Spith_1508 Spith_1509
SFCSpiaf_1750 Spiaf_2407 Spiaf_2409
SPEREW093_05445 EW093_05450
SLRL21SP2_0274 L21SP2_0275
OCKEXM22_15350 EXM22_15355(nuoF) EXM22_15360
SBUSpiBuddy_2313 SpiBuddy_2314
SCCSpico_0354
SGPSpiGrapes_2477 SpiGrapes_2478
BHCJFL75_09000 JFL75_09005
TPXTurpa_2746
BHYBHWA1_02502(hymC) BHWA1_02503(nuoF)
BHDBHYOB78_03730 BHYOB78_03735
BRMBmur_2160
BIPBint_0726(hymC) Bint_0727(nuoF)
BHPBHAMNSH16_10855 BHAMNSH16_10860
EMIEmin_0532 Emin_0533
EPOEpro_0734(hydA) Epro_0735(hydB) Epro_0736
FVAFV113G1_03860(nuoF) FV113G1_03870(nuoG) FV113G1_24290 FV113G1_26580
FULC4N20_00705 C4N20_04455 C4N20_04460 C4N20_10420
FMOC4N19_00165 C4N19_03610 C4N19_03615
FGOC4N16_04400
FNFBSQ88_02970 BSQ88_02975
IPOIlyop_0625 Ilyop_0626 Ilyop_0627 Ilyop_0628 Ilyop_0635 Ilyop_0689 Ilyop_0690 Ilyop_2431
LEOAMK43_00690 AMK43_00695 AMK43_00700
STRSterm_0623 Sterm_0624 Sterm_0625 Sterm_3599 Sterm_3600 Sterm_3601
TAITaci_0147 Taci_0148 Taci_0149 Taci_0150
ACOAmico_1557
TLITlie_1466 Tlie_1619
AMOAnamo_0024 Anamo_1679
CPORBED41_00310 BED41_00320 BED41_05425
BTHBT_0123 BT_0124 BT_0125
BTHOBtheta7330_03239(hndC) Btheta7330_03240(hndD) Btheta7330_03241(hndA)
BXYBXY_41360 BXY_41370 BXY_41380
BOABovatus_04980(hndA) Bovatus_04981(hndD) Bovatus_04982(hndC)
BCELBcellWH2_04988(hndC) BcellWH2_04989(hndD) BcellWH2_04990(hndA)
BCACCGC64_09630 CGC64_09635 CGC64_09640
BHFC3V43_03950 C3V43_03955 C3V43_03960
BISDXK01_013735 DXK01_013740 DXK01_013745(nuoE)
BFEK6V30_13375(nuoE) K6V30_13380 K6V30_13385
BNOK8P02_07460 K8P02_07465 K8P02_07470
BVUBVU_0396
PBTING2E5B_2397 ING2E5B_2398(hndC) ING2E5B_2399(hndD) ING2E5B_2400
PMUCING2E5A_0853(hndB) ING2E5A_0854(hndC) ING2E5A_0855(hndD) ING2E5A_0856(hndA)
PETPEIBARAKI_6525 PEIBARAKI_6526 PEIBARAKI_6527 PEIBARAKI_6528
PSACPSM36_3019 PSM36_3020(hndD) PSM36_3021(hndC) PSM36_3022
PDIBDI_1042 BDI_1043 BDI_1044 BDI_1045
PARCCI960_08930 CI960_08935 CI960_08940 CI960_08945
PMERINE87_00694(hndA) INE87_00695(hndD) INE87_00696(hndC) INE87_00697(hndB)
PGOLK6V26_09170 K6V26_09175 K6V26_09180 K6V26_09185
PJOLK449_07260 LK449_07265 LK449_07270 LK449_07275
OSPOdosp_0184 Odosp_0185 Odosp_0186 Odosp_0187
BUYD8S85_07440 D8S85_07445 D8S85_07450 D8S85_07455
BVIRI6J59_09400 I6J59_09405 I6J59_09410 I6J59_09415
RBCBN938_1638 BN938_2212 BN938_2258
TTZFHG85_08335 FHG85_08495 FHG85_09610(nuoE) FHG85_09615 FHG85_09620 FHG85_09625 FHG85_09660
BLQL21SP5_00769(hndB) L21SP5_00770(hndC_2) L21SP5_00771(hndD_1) L21SP5_00772(hndA_2) L21SP5_00830(hndD_2)
BACCBRDCF_p1395(nuoE2) BRDCF_p1396(nuoG) BRDCF_p1397(nuoF2) BRDCF_p1398 BRDCF_p1719
DORIFH5T_02925 FH5T_03065 FH5T_03070 FH5T_03075 FH5T_03080
DRCG0Q07_16470 G0Q07_16595 G0Q07_16600 G0Q07_16605 G0Q07_16610
MCOSGM418_18965 GM418_18970 GM418_18975 GM418_18980 GM418_20635
ASXCDL62_11530 CDL62_11585 CDL62_11590 CDL62_11595 CDL62_11600
MBASALGA_2626 ALGA_2627 ALGA_2628 ALGA_2629 ALGA_3125
RMRRmar_2590
RMGRhom172_2606
FLSGLV81_05450
MGOTMgSA37_01986(hoxY) MgSA37_01987(hoxH)
LUTLupro_00310
CPCCpar_0317 Cpar_0318
CLZBIU88_10290 BIU88_10295
CCHCag_0245
CPHCpha266_2168 Cpha266_2169
CPBCphamn1_2131 Cphamn1_2132
CLIClim_2096 Clim_2097
PPHPpha_2498 Ppha_2499
PAAPaes_1928 Paes_1929
PROCPtc2401_02008(hoxY) Ptc2401_02009(hoxH)
PRSB9H02_09675
PROSCHL67_10255 CHL67_10260
CTSCtha_0344
CACICLOAM1181 CLOAM1183(hymB) CLOAM1184
HTEHydth_0495 Hydth_0496
SAFSULAZ_0894 SULAZ_0896
PMXPERMA_0690 PERMA_0692
TAMTheam_0484
DTEDester_0745
TMATM0011
TMMTmari_0008 Tmari_0199
TMITHEMA_03725 THEMA_04745
TMWTHMA_0007 THMA_0208
TMQTHMB_0007 THMB_0208
TMXTHMC_0007 THMC_0208
TPTTpet_0912
TRQTRQ2_0934
TNACTN_0687
TNPTnap_0642
THQT2812B_03795 T2812B_04725
THZCELL2_04735
THRTRQ7_04910
TLETlet_1518 Tlet_1521
TTATheth_0092 Theth_1566 Theth_1569
PHYAJ81_00105 AJ81_08385 AJ81_08400
TMETmel_1168 Tmel_1171
TAFTHA_1554 THA_1558 THA_1808
THPBG95_06645 BG95_06660 BG95_08710
THERY592_06725 Y592_06740 Y592_08815
TFEJYK00_00830
FNOFnod_0236 Fnod_0991 Fnod_0994
FPEFerpe_0291 Ferpe_0292 Ferpe_1116 Ferpe_1120
FIANA23_05520 NA23_05535
OCYOSSY52_17030 OSSY52_21290(hymB) OSSY52_21300 OSSY52_21310
PMOPmob_0724 Pmob_0725 Pmob_0726 Pmob_1149
MPZMarpi_1895 Marpi_1896 Marpi_1897
MARNLN42_10050 LN42_10055
DTNDTL3_0214 DTL3_0799(hndD3)
KOLKole_0172 Kole_0181 Kole_0184
KPFIX53_02690 IX53_02705 IX53_02780
MPGTheba_0461 Theba_0464
MINFMESINF_2168 MESINF_2171
ASACATHSA_0551 ATHSA_0552 ATHSA_0845 ATHSA_1936
CPOCOPRO5265_0177 COPRO5265_0179 COPRO5265_0180 COPRO5265_0181
CEXCSE_11940 CSE_11960 CSE_11970
CNICalni_1549
CABYCabys_3228 Cabys_3229 Cabys_3677 Cabys_3678
DTHDICTH_0768
DTUDtur_0918
TYETHEYE_A1853 THEYE_A1854
DTPJZK55_04700(hydA) JZK55_04710 JZK55_05510 JZK55_11800 JZK55_21900 JZK55_21910 JZK55_21920
NIONITINOP_0586(hydA) NITINOP_0587(hydD)
THETF1847_07590
NLIG3M70_06690 G3M70_06695 G3M70_15045
ALAMRT761_02739(hndD_2)
BANABARAN1_0488 BARAN1_0490(HoxF) BARAN1_0495
BIHBIP78_1096 BIP78_1098 BIP78_1103
MOXDAMO_0854
WWEP147_WWE3C01G0331 P147_WWE3C01G0332
MIBUY43_C0001G0070
PFUPF0893 PF0894 PF1331 PF1332
PFIPFC_03675 PFC_03680 PFC_05870 PFC_05875
PHOPH1292(PH1292) PH1294(PH1294)
PABPAB0640(hydD-2) PAB0641(hydA-2) PAB1786 PAB1787
PYNPNA2_1551 PNA2_1553 PNA2_1665 PNA2_1666
PYAPYCH_00040 PYCH_00050 PYCH_08370 PYCH_08380
PYSPy04_0892 Py04_0893 Py04_1129 Py04_1130
PYCTQ32_02785 TQ32_02790 TQ32_03115 TQ32_03120
TKOTK2069 TK2070
TONTON_0052 TON_0053 TON_0534 TON_0535
TSITSIB_0284 TSIB_0285 TSIB_1522 TSIB_1523
TBATERMP_00069 TERMP_00070 TERMP_00536 TERMP_00537
THEGQS_02470 GQS_02475 GQS_04985 GQS_04990
THATAM4_296 TAM4_701 TAM4_99
THMCL1_0143 CL1_0144 CL1_0643 CL1_0644
TLTOCC_03062 OCC_03067 OCC_12216 OCC_12221
THSTES1_0166 TES1_0167
TNUBD01_0437 BD01_0438 BD01_2067 BD01_2068
TEUTEU_09725 TEU_09730
TGYX802_03245 X802_03250 X802_07560 X802_07565
THVADU37_CDS02170 ADU37_CDS02180 ADU37_CDS16280 ADU37_CDS16290
TCHCHITON_0949 CHITON_0950 CHITON_1019 CHITON_1020
TPEPA0127_05275 A0127_05280 A0127_07135 A0127_07140
TPIEA7C91_06185 A7C91_06190 A7C91_08725 A7C91_08730
TGGA3K92_08480 A3K92_08485
TCEA3L02_00965 A3L02_00970 A3L02_02385 A3L02_02390
TBSA3L01_00920 A3L01_00925 A3L01_03415 A3L01_03420
THHCDI07_00920 CDI07_00925 CDI07_03355 CDI07_03360
TSLA3L11_04675 A3L11_04680 A3L11_07375 A3L11_07380
TTDA3L14_02375 A3L14_02380 A3L14_05100 A3L14_05105
TPRFA3L09_05685 A3L09_05690 A3L09_05740 A3L09_05745
TRLA3L10_03150 A3L10_03155 A3L10_05635 A3L10_05640
TPAFA3L08_06480 A3L08_06485
THYA3L12_05480 A3L12_05485
TICFH039_02775 FH039_02780 FH039_05970 FH039_05975
TCQTIRI35C_0406(shyA) TIRI35C_0407(shyD) TIRI35C_0918(hydA) TIRI35C_0919(hydD)
THEMFPV09_03375 FPV09_03380 FPV09_06575 FPV09_06580
PPACPAP_01490 PAP_01495 PAP_03250 PAP_03255
MCJMCON_3103(nuoF)
HUTHuta_2099 Huta_2604 Huta_2605
HTIHTIA_1871 HTIA_2365
HALAHrd1104_08655 Hrd1104_08660
HDSHSR122_2937(frhA)
HARCHARCEL1_01230
HDFAArcSl_2420 AArcSl_2421
ABIAboo_0080 Aboo_0081
ACFAciM339_0970 AciM339_0971
THGTCELL_1052 TCELL_1053
FFOFFONT_1018 FFONT_1019
NCVNCAV_0543 NCAV_0544
CSUCSUB_C1023
KCRKcr_0321 Kcr_0322
BARBAOA66_1503(shyD) AOA66_1504(hydA)
LOKILokiarch_31190
PSYTDSAG12_03219(shyD)
AGWQT03_C0001G0117 QT03_C0001G0118
 » show all
Reference
1  [PMID:9703971]
  Authors
de Luca G, de Philip P, Rousset M, Belaich JP, Dermoun Z
  Title
The NADP-reducing hydrogenase of Desulfovibrio fructosovorans: evidence for a native complex with hydrogen-dependent methyl-viologen-reducing activity.
  Journal
Biochem Biophys Res Commun 248:591-6 (1998)
DOI:10.1006/bbrc.1998.9022
  Sequence
Reference
2  [PMID:2538471]
  Authors
Bryant FO, Adams MW
  Title
Characterization of hydrogenase from the hyperthermophilic archaebacterium, Pyrococcus furiosus.
  Journal
J Biol Chem 264:5070-9 (1989)
  Sequence
Reference
3  [PMID:8389482]
  Authors
Ma K, Schicho RN, Kelly RM, Adams MW
  Title
Hydrogenase of the hyperthermophile Pyrococcus furiosus is an elemental sulfur reductase or sulfhydrogenase: evidence for a sulfur-reducing hydrogenase ancestor.
  Journal
Proc Natl Acad Sci U S A 90:5341-4 (1993)
DOI:10.1073/pnas.90.11.5341
Reference
4
  Authors
Ma, K., Zhou, Z.H. and Adams, M.W.
  Title
Hydrogen production from pyruvate by enzymes purified from the hyperthermophilic archaeon, Pyrococcus furiosus: A key role for NADPH.
  Journal
FEMS Microbiol Lett 122:245-250 (1994)
Reference
5  [PMID:18156274]
  Authors
van Haaster DJ, Silva PJ, Hagedoorn PL, Jongejan JA, Hagen WR
  Title
Reinvestigation of the steady-state kinetics and physiological function of the soluble NiFe-hydrogenase I of Pyrococcus furiosus.
  Journal
J Bacteriol 190:1584-7 (2008)
DOI:10.1128/JB.01562-07
Other DBs
ExplorEnz - The Enzyme Database: 1.12.1.3
IUBMB Enzyme Nomenclature: 1.12.1.3
ExPASy - ENZYME nomenclature database: 1.12.1.3
BRENDA, the Enzyme Database: 1.12.1.3
CAS: 9027-05-8
LinkDB

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