KEGG ENZYME: 1.14.13.226

ENZYME: 1.14.13.226

Entry

EC 1.14.13.226              Enzyme

Name

acetone monooxygenase (methyl acetate-forming);
acmA (gene name)

Class

Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor

Sysname

acetone,NADPH:oxygen oxidoreductase (methyl acetate-forming)

Reaction(IUBMB)

acetone + NADPH + H+ + O2 = methyl acetate + NADP+ + H2O [RN:R10704]

Reaction(KEGG)

R10704

Substrate

acetone [CPD:C00207];
NADPH [CPD:C00005];
H+ [CPD:C00080];
O2 [CPD:C00007]

Product

methyl acetate [CPD:C17530];
NADP+ [CPD:C00006];
H2O [CPD:C00001]

Comment

Contains FAD. The enzyme, characterized from the bacterium Gordonia sp. TY-5, is a Baeyer-Villiger type monooxygenase and participates in a propane utilization pathway.

History

EC 1.14.13.226 created 2016

Pathway

ec00650

Butanoate metabolism

ec01100

Metabolic pathways

Orthology

K18371

acetone monooxygenase (methyl acetate-forming)

Genes

PVR:	PverR02_15355

GAI:	IMCC3135_04360(pamO)

BUZ:	AYM40_26480

MELA:

C6568_09580

MPT:	Mpe_A0393 Mpe_A1351 Mpe_B0610

METP:

C1M51_01470 C1M51_11100

ATER:

MW290_07650

AON:	DEH84_16250

METR:

BSY238_1123 BSY238_2655(pamO)

AZQ:	G3580_01435

BIC:	LMTR13_14840

BRK:	CWS35_07445

BOT:	CIT37_15830

BEL:	BE61_05150

BSEP:

HAP48_0013925

BQB:	J4P68_0017965

BAUT:

QA635_02420

BBRA:

QA636_02415

BPAH:

QA639_02350

BXN:	I3J27_03590

BRAZ:

LRP30_02450

RHOR:

ONR75_10755

MIND:

mvi_45310

MOG:	MMB17_17605

BID:

Bind_3904

RUT:	FIU92_22085(pamO)

DSH:	Dshi_2283(pamO)

TOM:	BWR18_02365

SAGU:

CDO87_05620

THAA:

CFI11_16920

HML:	HmaOT1_18900

SPHD:

HY78_07980

SROE:

JL101_032760

TMO:	TMO_c0213(pamO)

RHA:	RHA1_ro08185 RHA1_ro10187

RPY:	Y013_12765

RBY:	CEJ39_00255

RHQ:	IM25_04320

ROZ:	CBI38_31610

GBR:

Gbro_0088

GPO:	GPOL_c02620

GIT:	C6V83_11880

GOM:	D7316_03881(pamO_3)

GPD:	GII33_00770

GOI:	LK459_08565

OFA:	NF556_06270

NAQU:

ENKNEFLB_03695

NML:

Namu_3461

GOB:

Gobs_1837

PAUT:

Pdca_23100

PBRO:

HOP40_31185

ACTY:

OG774_13790

» show all

Reference

1 [PMID:17071761]

Authors

Kotani T, Yurimoto H, Kato N, Sakai Y

Title

Novel acetone metabolism in a propane-utilizing bacterium, Gordonia sp. strain TY-5.

Journal

J Bacteriol 189:886-93 (2007)
DOI:10.1128/JB.01054-06

Other DBs

ExplorEnz - The Enzyme Database:

1.14.13.226

IUBMB Enzyme Nomenclature:

1.14.13.226

ExPASy - ENZYME nomenclature database:

1.14.13.226

BRENDA, the Enzyme Database:

1.14.13.226

LinkDB

DBGET integrated database retrieval system