| Entry |
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| Name |
oryzalexin E synthase;
CYP76M6
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| Class |
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
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| Sysname |
ent-sandaracopimaradien-3beta-ol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (oryzalexin E forming)
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| Reaction(IUBMB) |
ent-sandaracopimaradien-3beta-ol + [reduced NADPH---hemoprotein reductase] + O2 = oryzalexin E + [oxidized NADPH---hemoprotein reductase] + H2O [RN: R11657]
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| Reaction(KEGG) |
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| Substrate |
ent-sandaracopimaradien-3beta-ol [CPD: C21560];
[reduced NADPH---hemoprotein reductase] [CPD: C03024];
O2 [CPD: C00007]
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| Product |
oryzalexin E [CPD: C21561];
[oxidized NADPH---hemoprotein reductase] [CPD: C03161];
H2O [CPD: C00001]
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| Comment |
A cytochrome P-450 (heme-thiolate) protein. Isolated from Oryza sativa (rice). Oryzalexin E is a phytoalexin.
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| History |
EC 1.14.14.122 created 2014 as EC 1.14.13.192, transferred 2018 to EC 1.14.14.122
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| Pathway |
| ec01110 | Biosynthesis of secondary metabolites |
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| Orthology |
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| Genes |
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| Reference |
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| Authors |
Wu Y, Wang Q, Hillwig ML, Peters RJ |
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| Title |
Picking sides: distinct roles for CYP76M6 and CYP76M8 in rice oryzalexin biosynthesis. |
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| Journal |
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| Sequence |
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| Other DBs |
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| LinkDB |
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