Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
BRITE hierarchy

methyl (2E,6E)-farnesoate,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase

methyl (2E,6E)-farnesoate + [reduced NADPH---hemoprotein reductase] + O2 = juvenile hormone III + [oxidized NADPH---hemoprotein reductase] + H2O [RN:R08148]

R08148
Reaction

methyl (2E,6E)-farnesoate [CPD:C16503];
[reduced NADPH---hemoprotein reductase] [CPD:C03024];
O2 [CPD:C00007]

A cytochrome P-450 (heme-thiolate) protein. The enzyme, found in insects except for Lepidoptera (moths and butterflies) is specific for methyl farnesoate (cf. EC 1.14.14.128, farnesoate epoxidase) [1,2].

EC 1.14.14.127 created 2015 as EC 1.14.13.202, transferred 2018 to EC 1.14.14.127

1  [PMID:15024118]

Helvig C, Koener JF, Unnithan GC, Feyereisen R

CYP15A1, the cytochrome P450 that catalyzes epoxidation of methyl farnesoate to juvenile hormone III in cockroach corpora allata.

Proc Natl Acad Sci U S A 101:4024-9 (2004)
DOI:10.1073/pnas.0306980101

[ag:AAS13464]

2  [PMID:23586995]

Daimon T, Shinoda T

Function, diversity, and application of insect juvenile hormone epoxidases (CYP15).

Biotechnol Appl Biochem 60:82-91 (2013)
DOI:10.1002/bab.1058