Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
BRITE hierarchy

[glycine cleavage system H]-N6-octanoyl-L-lysine:[lipoyl-carrier protein]-N6-L-lysine octanoyltransferase

[glycine cleavage system H]-N6-octanoyl-L-lysine + a [lipoyl-carrier protein] = glycine cleavage system H + a [lipoyl-carrier protein]-N6-octanoyl-L-lysine [RN:R12425]

R12425
Reaction

[glycine cleavage system H]-N6-octanoyl-L-lysine [CPD:C22159];
[lipoyl-carrier protein]

In the bacterium Bacillus subtilis it has been shown that the enzyme catalyses the
amidotransfer of the octanoyl moiety from [glycine cleavage system H]-N6-octanoyl-L-lysine (i.e. octanoyl-GcvH) to the E2 subunit (dihydrolipoamide acetyltransferase) of pyruvate dehydrogenase.

EC 2.3.1.204 created 2012

1  [PMID:21338421]

Christensen QH, Martin N, Mansilla MC, de Mendoza D, Cronan JE

A novel amidotransferase required for lipoic acid cofactor assembly in Bacillus subtilis.

Mol Microbiol 80:350-63 (2011)
DOI:10.1111/j.1365-2958.2011.07598.x

[bsu:BSU37640]

2  [PMID:21338420]

Martin N, Christensen QH, Mansilla MC, Cronan JE, de Mendoza D

A novel two-gene requirement for the octanoyltransfer reaction of Bacillus subtilis lipoic acid biosynthesis.

Mol Microbiol 80:335-49 (2011)
DOI:10.1111/j.1365-2958.2011.07597.x

[bsu:BSU37640]