Entry |
|
Name |
choline O-acetyltransferase;
choline acetylase;
choline acetyltransferase
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Class |
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
|
Sysname |
acetyl-CoA:choline O-acetyltransferase
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Reaction(IUBMB) |
acetyl-CoA + choline = CoA + O-acetylcholine [RN: R01023]
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Reaction(KEGG) |
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Substrate |
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Product |
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Comment |
Propanoyl-CoA can act, more slowly, in place of acetyl-CoA.
|
History |
EC 2.3.1.6 created 1961
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Pathway |
ec00564 | Glycerophospholipid metabolism |
|
Orthology |
K00623 | choline O-acetyltransferase |
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Genes |
» show all
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Reference |
|
Authors |
BERMAN R, WILSON IB, NACHMANSOHN D. |
Title |
Choline acetylase specificity in relation to biological function. |
Journal |
|
Reference |
|
Authors |
BERRY JF, WHITTAKER VP. |
Title |
The acyl-group specificity of choline acetylase. |
Journal |
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Reference |
|
Authors |
FRITZ IB, SCHULTZ SK. |
Title |
CARNITINE ACETYLTRANSFERASE. II. INHIBIITON BY CARNITINE ANALOGUES AND BY SULFHYDRYL REAGENTS. |
Journal |
J Biol Chem 240:2188-92 (1965) |
Reference |
4 |
Authors |
Schuberth, J. |
Title |
Choline acetyltransferase. Purification and effect of salts on the mechanism of the enzyme-catalysed reaction. |
Journal |
Biochim Biophys Acta 122:470-481 (1966) |
Other DBs |
ExplorEnz - The Enzyme Database: | 2.3.1.6 |
ExPASy - ENZYME nomenclature database: | 2.3.1.6 |
BRENDA, the Enzyme Database: | 2.3.1.6 |
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LinkDB |
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