Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
BRITE hierarchy

S-adenosyl 3-(methylsulfanyl)propylamine:propane-1,3-diamine 3-aminopropyltransferase

S-adenosyl 3-(methylsulfanyl)propylamine + propane-1,3-diamine = S-methyl-5'-thioadenosine + bis(3-aminopropyl)amine [RN:R03271]

R03271
Reaction

S-adenosyl 3-(methylsulfanyl)propylamine [CPD:C01137];
propane-1,3-diamine [CPD:C00986]

The enzyme has been originally characterized from the protist Euglena gracilis [1,2]. The enzyme from the archaeon Sulfolobus solfataricus can transfer the propylamine moiety from S-adenosyl 3-(methylsulfanyl)propylamine to putrescine, sym-norspermidine and spermidine with lower efficiency [3]. cf. EC 2.5.1.16 (spermidine synthase) and EC 2.5.1.22 (spermine synthase).

EC 2.5.1.23 created 1983, modified 2013

1  [PMID:116684]

Aleksijevic A, Grove J, Schuber F.

Studies on polyamine biosynthesis in Euglena gracilis.

Biochim Biophys Acta 565:199-207 (1979)
DOI:10.1016/0005-2787(79)90096-0

2

Villanueva, V.R., Adlakha, R.C. and Calbayrac, R.

Biosynthesis of polyamines in Euglena gracilis.

Phytochemistry 19:787-790 (1980)

3  [PMID:3096734]

Cacciapuoti G, Porcelli M, Carteni-Farina M, Gambacorta A, Zappia V

Purification and characterization of propylamine transferase from Sulfolobus solfataricus, an extreme thermophilic archaebacterium.

Eur J Biochem 161:263-71 (1986)
DOI:10.1111/j.1432-1033.1986.tb10442.x

[sso:SSO0757]