| Entry |
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| Name |
adenosylmethionine cyclotransferase;
adenosylmethioninase
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| Class |
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
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| Sysname |
S-adenosyl-L-methionine alkyltransferase (cyclizing)
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| Reaction(IUBMB) |
S-adenosyl-L-methionine = S-methyl-5'-thioadenosine + 2-aminobutan-4-olide [RN: R00180]
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| Reaction(KEGG) |
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| Substrate |
S-adenosyl-L-methionine [CPD: C00019]
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| Product |
S-methyl-5'-thioadenosine [CPD: C00170];
2-aminobutan-4-olide [CPD: C02926]
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| History |
EC 2.5.1.4 created 1965
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| Reference |
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| Authors |
MUDD SH. |
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| Title |
Enzymatic cleavage of S-adenosylmethionine. |
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| Journal |
J Biol Chem 234:87-92 (1959) |
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| Reference |
|
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| Authors |
MUDD SH. |
|---|
| Title |
The mechanism of the enzymatic cleavage of S-adenosylmethionine to alpha-amino-gamma-butyrolactone. |
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| Journal |
J Biol Chem 234:1784-6 (1959) |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.5.1.4 |
| ExPASy - ENZYME nomenclature database: | 2.5.1.4 |
| BRENDA, the Enzyme Database: | 2.5.1.4 |
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| LinkDB |
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