KEGG ENZYME: 2.5.1.43

ENZYME: 2.5.1.43

Entry

EC 2.5.1.43                 Enzyme

Name

nicotianamine synthase

Class

Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

Sysname

S-adenosyl-L-methionine:S-adenosyl-L-methionine:S-adenosyl-L-methionine 3-amino-3-carboxypropyltransferase

Reaction(IUBMB)

3 S-adenosyl-L-methionine = 3 S-methyl-5'-thioadenosine + nicotianamine [RN:R00075]

Reaction(KEGG)

R00075

Substrate

S-adenosyl-L-methionine [CPD:C00019]

Product

S-methyl-5'-thioadenosine [CPD:C00170];
nicotianamine [CPD:C05324]

History

EC 2.5.1.43 created 1999

Pathway

ec00270

Cysteine and methionine metabolism

ec00999

Biosynthesis of various plant secondary metabolites

ec01100

Metabolic pathways

ec01110

Biosynthesis of secondary metabolites

Orthology

K05953

nicotianamine synthase

Genes

BCOO:

119070648

BTAB:

109044732

ATH:	AT1G09240(NAS3) AT1G56430(NAS4) AT5G04950(NAS1) AT5G56080(NAS2)

ALY:	9300505 9309245 9328021 9328557

CRB:	17877070 17880913 17881818 17896008 17898438

CSAT:

104701054 104708618 104717596 104730756 104732729 104734502 104739516 104754956 104755112 104758977 104761659 104766177 104767547 104768692 104787782 104789480

EUS:	EUTSA_v10008206mg EUTSA_v10013812mg EUTSA_v10014123mg EUTSA_v10024166mg EUTSA_v10026750mg

BRP:	103845041 103847238 103847645 103851850 103855599 103866247 103867728 103871652

BNA:	106346288 106370283 106379260 106379334 106385040 106412811 106416128 106418370 106428166 106444095 106445243 106453283 111213986 125579103 125587435

BOE:	106294597 106310962 106315343 106316021 106325609 106327744 106329314

RSZ:	108816722 108840442 108841297 108843450 108844640 108845407 108850421 108860857 130507416

THJ:	104811690 104816890 104820632

CPAP:

110815380 110821244 110826411

CIT:	102608515 102609096 102609958 102621359

CIC:	CICLE_v10001872mg CICLE_v10010328mg CICLE_v10010369mg CICLE_v10010452mg CICLE_v10010757mg

PVY:	116106954 116108649 116108744 116108807 116108817 116115971 116115972 116117803

MINC:

123193914 123206447 123221634

TCC:	18589241 18600574 18603633

GRA:	105761119 105767526 105781107 105792468 105793510

GHI:	107888338 107893879 107894796 107919611 107926213 107927171 107933758 121209352 121217412 121229198

GAB:	108463453 108468137 108469508 108472923

HSYR:

120117544 120124664 120157069 120189659

DZI:	111277381 111296000 111301967 111307514

EGR:	104414670 104428248

RARG:

115751266 115752838

GMX:	100775553 100794250 100803630 100814069 100819726

GSJ:	114367111 114387347 114399003 114407543 114424311

PVU:	137814907 137831934 137835006

VRA:	106754071 106756794 106761843

VAR:	108328177 108333725 108342357

VUN:	114186325 114187489 114194913

VUM:	124829350 124838978 124846082

CCAJ:

109790589 109797885 109806164

APRC:

113853087 113856646 113861932

MTR:	11405947 11412482 25487054 25499657

TPRA:

123885093 123890199 123890973 123898269

CAM:	101509924 101510352 101513314 101514194

PSAT:

127092673 127115345 127132446

VVO:	131598892 131598893 131598894 131612805 131612807 131615868 131629605

LJA:	130726728 130730920 130749820

ADU:	107459596 107465178 107492163

AIP:	107612042 107619807 107645954

AHF:	112695583 112703449 112710725 112758211 112768963 112779605

LANG:

109332192 109345844 109353668 109353704 109353753 109354068 109354808

PCIN:

129306734 129314816 129315568 129317812

QSA:	O6P43_002874 O6P43_007426 O6P43_011034

FVE:	101313617 101314050

AANS:

126799344

RCN:	112180476 112193312

PPER:

18772486 18790379

PMUM:

103323493 103344131

PAVI:

110747490 110762851

PDUL:

117622689 117631595

MDM:	103433868 103450853

MSYL:

126594154 126617673

PXB:	103930560 103962314

PCOX:

137723475 137746238

ZJU:	107418990 125421187

MNT:	21385396 21405701

CSAV:

115694819 115718660 115718661 115720795 115720829 115721204 115722005 133035042

CSV:	101203651 101209464 101218907 101219339

CMO:	103492113 103494174 103494189 103494275

BHJ:	120070769 120071986 120080081 120080591

MCHA:

111023309 111025239

CMAX:

111465632 111485338 111486493 111493502

CMOS:

111430119 111437742 111444226 111450477

CPEP:

111780548 111785688 111792563 111799305 111804749

RCU:	8258799 8261713 8261714 8269821

MEAN:

126669664 126670448 126675397

JCU:	105635605 105635610 105643528 105647424

HBR:	110645864 110651885

MESC:

110600540 110620263 110621562 110623696 110630864 110630877

POP:	112327508 18098035

PEU:	105112194 105115144 105135643

PALZ:

118038804 118046328 118047659 118051673

PNZ:	133694303 133696044 133698202

JRE:	108981230 108987758 108998835

CILL:

122316727 122317470 122318255

CAVE:

132171738

AGLU:

133852073

QSU:	111986344 112028738

QLO:	115980241 115981763 115981915 115994087

TWL:	119996994 120006679 120008560 120010986 120013803

VVI:	100244492 100254544

VRI:	117924928 117929515

SLY:	101248619(CHLN)

SPEN:

107011178

SOT:

102578513

SSTN:

125851975

SDUL:

129884642

CANN:

107839697

LBB:

132598441

NTA:	107762888 107808712(NtNAS1) 107814310 107817799(NtNAS2)

NSY:	104237053 104249606

NTO:	104104973 104111414

NAU:	109223070 109233844

INI:	109174557 109180988 109182336

ITR:	116005496 116007614 116025017

SIND:

105168955 105172429

OEU:	111385856 111390250 111409892

EGT:	105954593 105958225

SSPL:

121754187 121758965 121807355

SMIL:

131009005 131009460

SHIS:

125193681 125219049

APAN:

127257173

PEBU:

140830229

HAN:	110877899 110885610 110890233 110913169 110932790

ECAD:

122593477 122594208 122596364

LSV:	111878037 111878402 111878404 111878908

CCAV:

112503529 112505540

DCR:	108200806 108210142 108226336

CSIN:

114279165 114297104

RVL:

131307468

AEW:	130750111 130754407 130758937 130775573 130778433 130785706

DLT:	127801048 127809745

BVG:

104890766

SOE:

110796718

CQI:	110701176 110736499

ATRI:

130796950 130817861

SLAF:

141639155

MOF:	131153219 131153625

NNU:	104598782 104605079

MING:

122085701 122090294 122091275

TSS:	122646631 122660360 122669296

PSOM:

113286440 113286441 113291814 113301249 113306976 113326007 113332641 113333378 113334895 113348128 113348893 113352648 113352966 113352967 113352968 113353597 113353598 113353600 113353604 113354002 113354003 113358139 113359469 113361277

OSA:	4332607(NAS2) 4332608(NAS1) 4344361(NAS3)

DOSA:

Os03g0307200 Os03g0307300 Os07g0689600

OBR:	102699669 102702270 102715132 121055712

OGL:	127767494 127767495 127778641

BDI:	100822873 100826723 100829217 100832895 100845767

ATS:	109733201 109738215 109738921 109739435 109741827 109748004 109776735 109777780 109779038 109787587 109787589

TDC:	119285513 119296327 119304374 119314708 119314969 119316430 119316432 119316457 119318492 119323111 119323112 119325023 119326313 119326368 119352811 119352918 119353188 119361851 119361948 119362308

TAES:

123040191 123043227 123043598 123048357 123051093 123051465 123059244 123083766 123094885 123097678 123099214 123099216 123106176 123106177 123130292 123130501 123130503 123130517 123131325 123131371 123133989 123133995 123135012 123135099 123141357 123141358 123142182 123144159 123146117 123184397 123187039 123187403

TUA:	125511657 125512992 125513000 125513062 125514551 125514663 125527469 125535178 125535247 125535551 125540768 125549185 125553908 125553909

LPER:

127295613 127305698 127327535 127331413 127331752 127334576 127336359 127345328

LRD:	124647583 124662036 124667091 124675918 124676040 124677875 124678417 124687245 124691561 124698080

SBI:	110435426 8057220 8077509

ZMA:	100191831 100284978 100285295 103634563 103639224 103643789 109942391 110386945 541637 542480

MFLO:

136495862 136495870 136495881 136495891 136495900 136495911 136500295 136522211 136532572 136532579 136533168 136547527 136547570 136552972

SITA:

101770261 101774809 101786975

SVS:	117840190 117843618

PVIR:

120652617 120662235 120690551 120694915

PHAI:

112873937 112876381 112880351

PAUA:

133891767 133891951 133911010 133911011 133914354 133916252

TANG:

140765598 140776623

PDA:	103698830 103700975

EGU:	105045032 105057353

MUS:	103968353 135612843 135626720 135627387

ZOF:	122000908 122003540 122019124 122050754

DCT:

110105313

PEQ:

110032766

AOF:	109835915 109842924 109850903

MSIN:

131217155 131225701 131256115 131256116 131256331

ACAK:

137950182 137956895 137960492

NCOL:

116250413 116254804 116262031

ATR:	18430237 18434693

CJF:	131046836 131053021 131060396 131065017 131077237

» show all

Reference

Authors

Higuchi K, Kanazawa K, Nishizawa N-K, Chino M, Mori S.

Title

Purification and characterization of nicotianamine synthase from Fe-deficient barley root.

Journal

Plant Soil 165:173-179 (1994)

Other DBs

ExplorEnz - The Enzyme Database:

2.5.1.43

IUBMB Enzyme Nomenclature:

2.5.1.43

ExPASy - ENZYME nomenclature database:

2.5.1.43

BRENDA, the Enzyme Database:

2.5.1.43

CAS:	161515-44-2

LinkDB

DBGET integrated database retrieval system