Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
BRITE hierarchy

O-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase

O-acetyl-L-serine + uracil = 3-(uracil-1-yl)-L-alanine + acetate [RN:R03131]

R03131
Reaction

O-acetyl-L-serine [CPD:C00979];
uracil [CPD:C00106]

The enzyme produces the non-proteinogenic amino acid L-willardiine, which is naturally found in the plants Acacia willardiana, Mimosa pigra, and Pisum sativum (pea). The enzyme from Pisum species also produces L-isowillardiine. Not identical with EC 2.5.1.47 cysteine synthase.

EC 2.5.1.53 created 1990 as EC 4.2.99.16, transferred 2002 to EC 2.5.1.53

1

Ahmmad, M.A.S., Maskall, C.S. and Brown, E.G.

Partial-purification and properties of willardiine and synthase activity from Pisum sativum.

Phytochemistry 23:265-270 (1984)

2

Ikegami, F., Kaneko, M., Lambein, F., Kuo, Y.-H. and Murakoshi, I.

Difference between uracilylalanine synthases and cysteine synthases in Pisum sativum.

Phytochemistry 26:2699-2704 (1987)

3

Murakoshi, I., Ikegami, F., Ookawa, N., Ariki, T., Haginiwa, J., Kuo, Y.-H. and Lambein, F.

Biosynthesis of the uracilylalanines willardiine and isowillardiine in higher plants.

Phytochemistry 17:1571-1576 (1978)