Entry |
|
Name |
uracilylalanine synthase;
O3-acetyl-L-serine acetate-lyase (adding uracil);
isowillardiine synthase;
willardiine synthase;
3-O-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase;
O3-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase
|
Class |
Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
|
Sysname |
O-acetyl-L-serine:uracil 1-(2-amino-2-carboxyethyl)transferase
|
Reaction(IUBMB) |
O-acetyl-L-serine + uracil = 3-(uracil-1-yl)-L-alanine + acetate [RN: R03131]
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Reaction(KEGG) |
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Substrate |
|
Product |
3-(uracil-1-yl)-L-alanine [CPD: C03584];
acetate [CPD: C00033]
|
Comment |
The enzyme produces the non-proteinogenic amino acid L-willardiine, which is naturally found in the plants Acacia willardiana, Mimosa pigra, and Pisum sativum (pea). The enzyme from Pisum species also produces L-isowillardiine. Not identical with EC 2.5.1.47 cysteine synthase.
|
History |
EC 2.5.1.53 created 1990 as EC 4.2.99.16, transferred 2002 to EC 2.5.1.53
|
Reference |
1 |
Authors |
Ahmmad, M.A.S., Maskall, C.S. and Brown, E.G. |
Title |
Partial-purification and properties of willardiine and synthase activity from Pisum sativum. |
Journal |
Phytochemistry 23:265-270 (1984) |
Reference |
2 |
Authors |
Ikegami, F., Kaneko, M., Lambein, F., Kuo, Y.-H. and Murakoshi, I. |
Title |
Difference between uracilylalanine synthases and cysteine synthases in Pisum sativum. |
Journal |
Phytochemistry 26:2699-2704 (1987) |
Reference |
3 |
Authors |
Murakoshi, I., Ikegami, F., Ookawa, N., Ariki, T., Haginiwa, J., Kuo, Y.-H. and Lambein, F. |
Title |
Biosynthesis of the uracilylalanines willardiine and isowillardiine in higher plants. |
Journal |
Phytochemistry 17:1571-1576 (1978) |
Other DBs |
ExplorEnz - The Enzyme Database: | 2.5.1.53 |
ExPASy - ENZYME nomenclature database: | 2.5.1.53 |
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LinkDB |
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