KEGG   ENZYME: 2.7.7.103
Entry
EC 2.7.7.103                Enzyme                                 

Name
L-glutamine-phosphate cytidylyltransferase
Class
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
Sysname
CTP:phosphoglutamine cytidylyltransferase
Reaction(IUBMB)
CTP + N5-phospho-L-glutamine = diphosphate + N5-(cytidine 5'-diphosphoramidyl)-L-glutamine [RN:R12247]
Reaction(KEGG)
R12247
Substrate
CTP [CPD:C00063];
N5-phospho-L-glutamine [CPD:C21785]
Product
diphosphate [CPD:C00013];
N5-(cytidine 5'-diphosphoramidyl)-L-glutamine [CPD:C22033]
Comment
The enzyme, characterized from the bacterium Campylobacter jejuni, is involved in formation of a unique O-methyl phosphoramidate modification on specific sugar residues within the bacterium's capsular polysaccharides.
History
EC 2.7.7.103 created 2018
Orthology
K01009  L-glutamine-phosphate cytidylyltransferase
Genes
DDC: Dd586_1833
HSO: HS_1459(licC)
HSM: HSM_0544
AAP: NT05HA_2256
XVA: C7V42_03515
XHY: FZ025_12095
PMK: MDS_1830
PPT: PPS_0777
PPB: PPUBIRD1_0772
PPUT: L483_03685
PMON: X969_02140
PMOT: X970_02120
PSEM: TO66_30425
SPL: Spea_1406
MHC: MARHY0659
AAUS: EP12_05185
HHA: Hhal_0773
AHA: AHA_4152
AAA: Acav_2125
NEU: NE0175
HHE: HH_1439
HCL: NCTC13205_00567(gtaB)
WSU: WS2178
CJE: Cj1416c
CJU: C8J_0637
CJI: CJSA_1347
CJM: CJM1_0655
CJEJ: N564_01413
CJEU: N565_01453
CJEN: N755_01450
CJEI: N135_01505
CJER: H730_08035
CJY: QZ67_01551(spsI)
CJQ: UC78_1358
CFZ: CSG_17660
CLA: CLA_0316
CCF: YSQ_05950
CCY: YSS_03090
CCOI: YSU_05600
CIS: CINS_0306
CSPF: CSF_1621
CCUN: CCUN_1303
HBV: ABIV_2412
GLO: Glov_3392
PPD: Ppro_2774
DVM: DvMF_0016
SCL: sce6079
AVI: Avi_7110
HNE: HNE_1579
SAL: Sala_2240
SPHU: SPPYR_2768
SWI: Swit_1309
SPHD: HY78_20025
SPHM: G432_14085
SSAN: NX02_25120
SPMI: K663_05290
SPHB: EP837_00690(ugp2)
SPHR: BSY17_2254
SINB: SIDU_02805
SPHT: K426_14915
SMIC: SmB9_21320
MAGX: XM1_2453
MAI: MICA_1015
BTM: MC28_4495
BMYC: DJ92_2314
SNE: SPN23F03310(wchZ)
LHV: lhe_0419
CPF: CPF_0610
CPR: CPR_0596
CTC: CTC_01704
CBT: CLH_2941
CBE: Cbei_4339
CBZ: Cbs_4339
CBEI: LF65_04863
RIM: ROI_07410
CCT: CC1_04130
CHY: CHY_2584
ERH: ERH_0405
ELE: Elen_2028
CBAC: JI75_05500
DDO: I597_2600
MARF: CJ739_2837
CPRV: CYPRO_1257
TAF: THA_1128
METM: MSMTP_1927
MBU: Mbur_0788
NPH: NP_1952A
NCT: NMSP_0153
PSYT: DSAG12_01619(aglF_1) DSAG12_01895(aglF_3)
 » show all
Reference
1  [PMID:29023101]
  Authors
Taylor ZW, Brown HA, Holden HM, Raushel FM
  Title
Biosynthesis of Nucleoside Diphosphoramidates in Campylobacter jejuni.
  Journal
Biochemistry 56:6079-6082 (2017)
DOI:10.1021/acs.biochem.7b00905
  Sequence
[cje:Cj1416c]
Other DBs
ExplorEnz - The Enzyme Database: 2.7.7.103
IUBMB Enzyme Nomenclature: 2.7.7.103
ExPASy - ENZYME nomenclature database: 2.7.7.103
BRENDA, the Enzyme Database: 2.7.7.103
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