Entry |
|
Name |
nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase;
NDP hexose pyrophosphorylase;
hexose 1-phosphate nucleotidyltransferase;
hexose nucleotidylating enzyme;
nucleoside diphosphohexose pyrophosphorylase;
hexose-1-phosphate guanylyltransferase;
GTP:alpha-D-hexose-1-phosphate guanylyltransferase;
GDP hexose pyrophosphorylase;
guanosine diphosphohexose pyrophosphorylase;
nucleoside-triphosphate-hexose-1-phosphate nucleotidyltransferase;
NTP:hexose-1-phosphate nucleotidyltransferase
|
Class |
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
|
Sysname |
NTP:alpha-D-aldose-1-phosphate nucleotidyltransferase
|
Reaction(IUBMB) |
nucleoside triphosphate + alpha-D-aldose 1-phosphate = diphosphate + NDP-hexose [RN: R03149]
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Reaction(KEGG) |
|
Substrate |
nucleoside triphosphate [CPD: C00201];
alpha-D-aldose 1-phosphate [CPD: C00991]
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Product |
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Comment |
In decreasing order of activity, guanosine, inosine and adenosine diphosphate hexoses are substrates in the reverse reaction, with either glucose or mannose as the sugar.
|
History |
EC 2.7.7.28 created 1972, modified 2004 (EC 2.7.7.29 created 1972, incorporated 2004)
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Reference |
|
Authors |
Verachtert H, Rodriguez P, Bass ST, Hansen RG. |
Title |
Purification and properties of guanosine diphosphate hexose pyrophosphorylase from mammalian tissues. |
Journal |
J Biol Chem 241:2007-13 (1966) |
Reference |
2 |
Authors |
Hansen, R.G., Verachtert, H., Rodriguez, P. and Bass, S.T. |
Title |
GDP-hexose pyrophosphorylase from liver. |
Journal |
Methods Enzymol 8:269-271 (1966) |
Other DBs |
ExplorEnz - The Enzyme Database: | 2.7.7.28 |
ExPASy - ENZYME nomenclature database: | 2.7.7.28 |
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LinkDB |
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