| Entry |
|
|---|
| Name |
nucleoside-triphosphate-aldose-1-phosphate nucleotidyltransferase;
NDP hexose pyrophosphorylase;
hexose 1-phosphate nucleotidyltransferase;
hexose nucleotidylating enzyme;
nucleoside diphosphohexose pyrophosphorylase;
hexose-1-phosphate guanylyltransferase;
GTP:alpha-D-hexose-1-phosphate guanylyltransferase;
GDP hexose pyrophosphorylase;
guanosine diphosphohexose pyrophosphorylase;
nucleoside-triphosphate-hexose-1-phosphate nucleotidyltransferase;
NTP:hexose-1-phosphate nucleotidyltransferase
|
|---|
| Class |
Transferases;
Transferring phosphorus-containing groups;
Nucleotidyltransferases
|
|---|
| Sysname |
NTP:alpha-D-aldose-1-phosphate nucleotidyltransferase
|
|---|
| Reaction(IUBMB) |
nucleoside triphosphate + alpha-D-aldose 1-phosphate = diphosphate + NDP-hexose [RN: R03149]
|
|---|
| Reaction(KEGG) |
|
|---|
| Substrate |
nucleoside triphosphate [CPD: C00201];
alpha-D-aldose 1-phosphate [CPD: C00991]
|
|---|
| Product |
|
|---|
| Comment |
In decreasing order of activity, guanosine, inosine and adenosine diphosphate hexoses are substrates in the reverse reaction, with either glucose or mannose as the sugar.
|
|---|
| History |
EC 2.7.7.28 created 1972, modified 2004 (EC 2.7.7.29 created 1972, incorporated 2004)
|
|---|
| Reference |
|
|---|
| Authors |
Verachtert H, Rodriguez P, Bass ST, Hansen RG. |
|---|
| Title |
Purification and properties of guanosine diphosphate hexose pyrophosphorylase from mammalian tissues. |
|---|
| Journal |
J Biol Chem 241:2007-13 (1966) |
|---|
| Reference |
2 |
|---|
| Authors |
Hansen, R.G., Verachtert, H., Rodriguez, P. and Bass, S.T. |
|---|
| Title |
GDP-hexose pyrophosphorylase from liver. |
|---|
| Journal |
Methods Enzymol 8:269-271 (1966) |
|---|
| Other DBs |
| ExplorEnz - The Enzyme Database: | 2.7.7.28 |
| ExPASy - ENZYME nomenclature database: | 2.7.7.28 |
|
|---|
| LinkDB |
|
|---|
