Entry
Name
succinyl-CoA:mesaconate CoA transferase;
mct (gene name)
Class
Transferases;
Transferring sulfur-containing groups;
CoA-transferases
BRITE hierarchy
Sysname
succinyl-CoA:mesaconate CoA transferase
Reaction(IUBMB)
succinyl-CoA + mesaconate = 2-methylfumaryl-CoA + succinate [RN:
R10904 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme participates in the methylaspartate cycle, an anaplerotic pathway that operates in some members of the haloarchaea and forms malate from acetyl-CoA.
History
EC 2.8.3.26 created 2020
Pathway
ec00630 Glyoxylate and dicarboxylate metabolism
ec01120 Microbial metabolism in diverse environments
Orthology
K19280 succinyl-CoA:mesaconate CoA transferase
Genes
» show all
Taxonomy
Reference
Authors
Khomyakova M, Bukmez O, Thomas LK, Erb TJ, Berg IA
Title
A methylaspartate cycle in haloarchaea.
Journal
Sequence
Reference
Authors
Borjian F, Johnsen U, Schonheit P, Berg IA
Title
Succinyl-CoA:Mesaconate CoA-Transferase and Mesaconyl-CoA Hydratase, Enzymes of the Methylaspartate Cycle in Haloarcula hispanica.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.8.3.26
ExPASy - ENZYME nomenclature database: 2.8.3.26
LinkDB
All DBs