KEGG   ENZYME: 3.4.17.4
Entry
EC 3.4.17.4                 Enzyme                                 
Name
Gly-Xaa carboxypeptidase;
glycine carboxypeptidase;
carboxypeptidase a;
carboxypeptidase S;
peptidase alpha;
yeast carboxypeptidase;
Gly-X carboxypeptidase
Class
Hydrolases;
Acting on peptide bonds (peptidases);
Metallocarboxypeptidases
Reaction(IUBMB)
Release of a C-terminal amino acid from a peptide in which glycine is the penultimate amino acid, e.g. Z-Gly!Leu
Comment
From yeast. In peptidase family M20 (glutamate carboxypeptidase family).
History
EC 3.4.17.4 created 1961 as EC 3.4.2.3, transferred 1972 to EC 3.4.12.8, transferred 1978 to EC 3.4.17.4 (EC 3.4.17.9 created 1981, incorporated 1992)
Orthology
K01293  Gly-Xaa carboxypeptidase
Genes
PFLV: 114571645
SCE: YJL172W(CPS1)
SEUB: DI49_2256 DI49_2856
SPAO: SPAR_J00430 SPAR_O00060
AGO: AGOS_AEL132W AGOS_AGL325W AGOS_AGL326W
ERC: Ecym_7172 Ecym_8112
KLA: KLLA0_A06512g KLLA0_E05655g KLLA0_E15005g KLLA0_F01903g
KMX: KLMA_50080(CPS1) KLMA_60021(CPS1) KLMA_70093(CPS1)
LTH: KLTH0E01804g KLTH0F04422g KLTH0H05500g
VPO: Kpol_1013p75 Kpol_1028p91
ZRO: ZYRO0F12958g ZYRO0G18832g
CGR: 2886851(GVI51_C00143)
NCS: NCAS_0I02900(NCAS0I02900)
NDI: NDAI_0B00280(NDAI0B00280)
TPF: TPHA_0E00410(TPHA0E00410)
TBL: TBLA_0A03770(TBLA0A03770)
TGB: HG536_0A02030 HG536_0B03750
TDL: TDEL_0G02050(TDEL0G02050)
KAF: KAFR_0F01750(KAFR0F01750)
KNG: KNAG_0C02380(KNAG0C02380) KNAG_0G02320(KNAG0G02320)
ZMK: HG535_0B04940 HG535_0C00120 HG535_0C00230 HG535_0C06590 HG535_0D00140 HG535_0H03530
SLUD: SCDLUD_001041 SCDLUD_001042 SCDLUD_003956
DHA: DEHA2G18326g DEHA2G19008g DEHA2G19030g
PIC: PICST_28659 PICST_34371(CPS1)
PGU: PGUG_02406 PGUG_04051 PGUG_05177
SPAA: SPAPADRAFT_141672 SPAPADRAFT_59054
LEL: PVL30_004099(CPS1) PVL30_005645
LBG: 92209370(LODBEIA_P41740) 92210222(LODBEIA_P50260)
CAL: CAALFM_C401830CA(CaO19.4610) CAALFM_C403050CA(CaO19.2686)
CTP: CTRG_00219 CTRG_00280 CTRG_00287
COT: CORT_0E00690 CORT_0E01590 CORT_0F02010
CDU: CD36_41720 CD36_42910
CTEN: 18245884(PSN45_004283) 18247187(CPS1) 18249504(PSN45_000381)
CLU: CLUG_05010 CLUG_05364
CLUS: A9F13_03g02244 A9F13_14g01419
CAUR: CJI96_0000943 CJI96_0001238
ASAU: 88172153(PUMCH_001085) 88172154(PUMCH_001086)
PPA: PAS_chr4_0686
PKZ: C5L36_0A09080 C5L36_0A09090 C5L36_0B05100 C5L36_0B12040
BBRX: BRETT_002575 BRETT_004038 BRETT_004040 BRETT_004074
OPA: HPODL_01101 HPODL_01409 HPODL_02377
YLI: 2907890(YALI2_E01002g) 2908881(YALI2_F00324g)
SLB: AWJ20_4433(CPS1) AWJ20_873(CPS1)
NCR: NCU11129
NTE: NEUTE1DRAFT59372(NEUTE1DRAFT_59372)
SMP: 10802243(SMAC4_08404)
PAN: PODANSg6107
PBEL: QC761_302940
PPSD: QC762_302940
PPSP: QC763_302940
PPSA: QC764_302940
TTT: THITE_2116166
MTM: MYCTH_2305453
CTHR: CTHT_0031810
RTHE: 98126371(VTJ83DRAFT_5158)
MGR: MGG_00309
PPEI: PpBr36_08844
PGRI: PgNI_09040
TMN: UCRPA7_1475 UCRPA7_5269 UCRPA7_8133
SSCK: SPSK_07339 SPSK_08902
FGR: FGSG_00017 FGSG_03967 FGSG_05050
FPU: FPSE_04941 FPSE_05308 FPSE_07853
FPOA: FPOAC1_000062
FVN: FVRRES_00172 FVRRES_07000 FVRRES_08485
FVR: FVEG_06007 FVEG_10115
FOX: FOXG_08666 FOXG_11699
NHE: NECHADRAFT_103332 NECHADRAFT_55460 NECHADRAFT_56807 NECHADRAFT_94988
FFC: NCS54_00224800 NCS54_00889000 NCS54_00934000
FKR: NCS57_00220300 NCS57_00953500
FMU: J7337_004762 J7337_011381
TRE: TRIREDRAFT_72086 TRIREDRAFT_72612
TRR: M419DRAFT_72409 M419DRAFT_86286
TATV: 25776255(TrAtP1_007527) 25780229(TrAtP1_013295)
TASP: 36610951(TrAFT101_007878)
PCHM: VFPPC_00060 VFPPC_04951
CMT: CCM_03576
AMUS: LMH87_010569
PLJ: 28883799(PLICBS_000266) 28891856(PLICBS_003981) 28892743(PLICBS_008998)
PTKZ: JDV02_001986(CPS1) JDV02_003344 JDV02_005690
VAL: VDBG_03460
VDA: VDAG_09927
CFJ: CFIO01_05421 CFIO01_08326
CLUP: CLUP02_11822
CHIG: CH63R_11325 CH63R_12260
CDET: 87946076(CDEST_09573) 87947018(CDEST_10516)
ELA: UCREL1_11295 UCREL1_4332 UCREL1_5971
PFY: PFICI_00240
MBE: MBM_02080
PSCO: LY89DRAFT_585974 LY89DRAFT_623713 LY89DRAFT_639349 LY89DRAFT_778755
ANI: ANIA_04810 ANIA_10986
AFM: AFUA_3G07040
ACT: ACLA_035000
NFI: NFIA_070210
AOR: AO090020000288
ANG: An02g13740
AFV: AFLA_010375
ALUC: AKAW2_11155S
ACHE: ACHE_70370S
APUU: APUU_31079S
PCS: N7525_008709
PDP: PDIP_09540
POU: POX_g08842
TMF: EYB26_008847
TRG: TRUGW13939_01626 TRUGW13939_11031
BGH: BDBG_03770
PNO: SNOG_06599
PTE: PTT_17392
PTRR: 6340525(PtrM4_058970)
BZE: COCCADRAFT_4372
BSC: COCSADRAFT_349396
BOR: COCMIDRAFT_6849
AALT: CC77DRAFT_1021811
ADAC: 96088278(ACET3X_007956)
ARAB: EKO05_0005964
ZTR: MYCGRDRAFT_71524
PFJ: MYCFIDRAFT_34215
FFU: CLAFUR5_08160
CBET: CB0940_04231
BCOM: BAUCODRAFT_123824
NPA: UCRNP2_1345
SPO: 2541555(cps1)
SOM: SOMG_00274(cps1)
CNE: CNA02910 CNB04480 CNG01640 CNI02790 CNL06270
CNB: CNBA2800 CNBB1280 CNBG3140 CNBH2660 CNBI0560
CNG: CNAG_00308 CNAG_03420 CNAG_03960 CNAG_04141 CNAG_04988
CGI: CGB_A1510W CGB_B3390C CGB_G4450W CGB_H5450C
CDEU: CNBG_2189 CNBG_2900 CNBG_5508 CNBG_9026
CDEC: 89988983(IAS62_002209) 89989151(IAS62_002378) 89989505(IAS62_002732) 89990193(IAS62_003421)
CTEG: 91988368(I308_101510) 91989525(I308_102669) 91991186(I308_104330) 91991806(I308_104950)
CBAS: 91981551(I312_101503) 91982741(I312_102694) 91983144(I312_103099) 91984908(I312_104863)
CDEP: 91087744(L203_103533)
KMG: 30159975(I203_104896) 30159976(I203_104895) 30165142(I203_108434) 30165866(I203_103347) 30166211(I203_104092)
KNE: 92177413(IAR55_000153) 92178927(IAR55_001668) 92179994(IAR55_002736) 92180617(IAR55_003359) 92181085(IAR55_003827) 92181258(IAR55_004000)
KDJ: 28964371(I303_100668) 28967181(I303_103459) 28967965(I303_104754) 28969825(I303_106107) 28969836(I303_106118) 28970197(I303_107097)
KBI: 30209488(I302_105965) 30211209(I302_107449) 30211210(I302_107448) 30211742(I302_108289) 30213470(I302_104859)
KPIN: 30170194(I206_103170) 30172129(I206_105330) 30172143(I206_105316) 30172671(I206_104122) 30173251(I206_106059)
KSH: 87955486(IL334_003355) 87956456(IL334_004325) 87956788(IL334_004657) 87957709(IL334_005578) 87957710(IL334_005579) 87959264(IL334_007134)
KER: 91099030(V865_000226) 91099031(V865_000227) 91099855(V865_001051) 91100593(V865_001789) 91106832(V865_008031)
TMS: TREMEDRAFT_30032 TREMEDRAFT_32403 TREMEDRAFT_33687 TREMEDRAFT_71337
TASA: A1Q1_06091 A1Q1_06716 A1Q1_07978
CCAC: CcaHIS019_0106720(CcaverHIS019_0106720) CcaHIS019_0207140(CcaverHIS019_0207140) CcaHIS019_0208330(CcaverHIS019_0208330) CcaHIS019_0407380(CcaverHIS019_0407380)
PPL: POSPLDRAFT_30883
TVS: TRAVEDRAFT_124091 TRAVEDRAFT_124267 TRAVEDRAFT_64964
DSQ: DICSQDRAFT_144908 DICSQDRAFT_53682 DICSQDRAFT_54091 DICSQDRAFT_54156
PCO: PHACADRAFT_105203 PHACADRAFT_130350 PHACADRAFT_188329
SHS: STEHIDRAFT_108027 STEHIDRAFT_122256 STEHIDRAFT_134952 STEHIDRAFT_156269 STEHIDRAFT_162657 STEHIDRAFT_165314 STEHIDRAFT_168086 STEHIDRAFT_55881 STEHIDRAFT_57863 STEHIDRAFT_58015 STEHIDRAFT_96332 STEHIDRAFT_97435
HIR: HETIRDRAFT_147361 HETIRDRAFT_64258 HETIRDRAFT_64447 HETIRDRAFT_64485
PSQ: PUNSTDRAFT_108063 PUNSTDRAFT_146350 PUNSTDRAFT_46418
ADL: AURDEDRAFT_162904 AURDEDRAFT_78000
FME: FOMMEDRAFT_137715 FOMMEDRAFT_16084 FOMMEDRAFT_164381
GTR: GLOTRDRAFT_105482 GLOTRDRAFT_120953 GLOTRDRAFT_138197
RSX: RhiXN_00232 RhiXN_00233 RhiXN_06323
LBC: LACBIDRAFT_182303 LACBIDRAFT_318408
CCI: CC1G_05710 CC1G_09019 CC1G_14879
ABP: AGABI1DRAFT106116(AGABI1DRAFT_106116) AGABI1DRAFT112074(AGABI1DRAFT_112074) AGABI1DRAFT36060(AGABI1DRAFT_36060)
ABV: AGABI2DRAFT143695(AGABI2DRAFT_143695) AGABI2DRAFT193317(AGABI2DRAFT_193317) AGABI2DRAFT212201(AGABI2DRAFT_212201)
MRR: Moror_14065 Moror_14076 Moror_15911
MORE: E1B28_006267 E1B28_007326
SCM: SCHCO_02513402(SCHCODRAFT_02513402) SCHCO_02572069(SCHCODRAFT_02572069) SCHCO_02609110(SCHCODRAFT_02609110) SCHCO_02630895(SCHCODRAFT_02630895) SCHCO_02630897(SCHCODRAFT_02630897)
CPUT: CONPUDRAFT_138391 CONPUDRAFT_59281
SLA: SERLADRAFT_345484 SERLADRAFT_345842 SERLADRAFT_351739 SERLADRAFT_440192 SERLADRAFT_472608
WSE: WALSEDRAFT_60314
WIC: J056_003068
UMA: UMAG_05897
PFP: PFL1_03556 PFL1_06703
SGRA: EX895_000861 EX895_003286
MGL: MGL_0256
MRT: MRET_1058
 » show all
Reference
1  [PMID:4961236]
  Authors
Felix F, Brouillet N.
  Title
[Purification and properties of 2 peptidases from baker's yeast]
  Journal
Biochim Biophys Acta 122:127-44 (1966)
Reference
2  [PMID:352726]
  Authors
Wolf DH, Ehmann C.
  Title
Carboxypetidase S from yeast: regulation of its activity during vegetative growth and differentiation.
  Journal
FEBS Lett 91:59-62 (1978)
DOI:10.1016/0014-5793(78)80017-9
Other DBs
ExplorEnz - The Enzyme Database: 3.4.17.4
IUBMB Enzyme Nomenclature: 3.4.17.4
ExPASy - ENZYME nomenclature database: 3.4.17.4
BRENDA, the Enzyme Database: 3.4.17.4
CAS: 9025-25-6
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