KEGG   ENZYME: 3.5.5.6
Entry
EC 3.5.5.6                  Enzyme                                 

Name
bromoxynil nitrilase
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In nitriles
Sysname
3,5-dibromo-4-hydroxybenzonitrile aminohydrolase
Reaction(IUBMB)
3,5-dibromo-4-hydroxybenzonitrile + 2 H2O = 3,5-dibromo-4-hydroxybenzoate + NH3 [RN:R04349]
Reaction(KEGG)
R04349
Substrate
3,5-dibromo-4-hydroxybenzonitrile [CPD:C04178];
H2O [CPD:C00001]
Product
3,5-dibromo-4-hydroxybenzoate [CPD:C03925];
NH3 [CPD:C00014]
Comment
Involved in the bacterial degradation of the herbicide bromoxynil. Highly specific.
History
EC 3.5.5.6 created 1992
Pathway
ec00364  Fluorobenzoate degradation
ec01120  Microbial metabolism in diverse environments
Orthology
K20806  bromoxynil nitrilase
Reference
1  [PMID:2834373]
  Authors
Stalker DM, Malyj LD, McBride KE
  Title
Purification and properties of a nitrilase specific for the herbicide bromoxynil and corresponding nucleotide sequence analysis of the bxn gene.
  Journal
J Biol Chem 263:6310-4 (1988)
  Sequence
Other DBs
ExplorEnz - The Enzyme Database: 3.5.5.6
IUBMB Enzyme Nomenclature: 3.5.5.6
ExPASy - ENZYME nomenclature database: 3.5.5.6
UM-BBD (Biocatalysis/Biodegradation Database): 3.5.5.6
BRENDA, the Enzyme Database: 3.5.5.6
CAS: 157857-12-0
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