Entry
Name
deacetylipecoside synthase;
deacetylipecoside dopamine-lyase;
deacetylipecoside dopamine-lyase (secologanin-forming)
Class
Hydrolases;
Acting on carbon-nitrogen bonds, other than peptide bonds;
In other compounds
BRITE hierarchy
Sysname
deacetylipecoside dopamine-hydroyase (secologanin-forming)
Reaction(IUBMB)
deacetylipecoside + H2O = dopamine + secologanin [RN:
R05749 ]
Reaction(KEGG)
Substrate
Product
Comment
The enzyme from the leaves of Alangium lamarckii differs in enantiomeric specificity from EC
3.5.99.15 , deacetylisoipecoside synthase. The product is rapidly converted to demethylalangiside.
History
EC 3.5.99.16 created 2000 as EC 4.3.3.4, transferred 2024 to EC 3.5.99.16
Pathway
ec00950 Isoquinoline alkaloid biosynthesis
Reference
1
Authors
DeEknamkul, W., Ounaroon, A., Tanahashi, T., Kutchan, T. and Zenk, M.H.
Title
Enzymatic condensation of dopamine and secologanin by cell-free extracts of Alangium lamarckii.
Journal
Phytochemistry 45:477-484 (1997)
Reference
Authors
De-Eknamkul W, Suttipanta N, Kutchan TM.
Title
Purification and characterization of deacetylipecoside synthase from Alangium lamarckii Thw.
Journal
Other DBs
ExPASy - ENZYME nomenclature database: 3.5.99.16
LinkDB
All DBs