KEGG ENZYME: 3.6.1.29

ENZYME: 3.6.1.29

Entry

EC 3.6.1.29 Enzyme

Name

bis(5'-adenosyl)-triphosphatase;
dinucleosidetriphosphatase;
diadenosine 5,5-P1,P3-triphosphatase;
1-P,3-P-bis(5'-adenosyl)-triphosphate adenylohydrolase

Class

Hydrolases;
Acting on acid anhydrides;
In phosphorus-containing anhydrides

Sysname

P1,P3-bis(5'-adenosyl)-triphosphate adenylohydrolase

Reaction(IUBMB)

P1,P3-bis(5'-adenosyl) triphosphate + H2O = ADP + AMP [RN:R00187]

Reaction(KEGG)

R00187

Substrate

P1,P3-bis(5'-adenosyl) triphosphate [CPD:C06197];
H2O [CPD:C00001]

Product

ADP [CPD:C00008];
AMP [CPD:C00020]

History

EC 3.6.1.29 created 1978

Pathway

ec00230

Purine metabolism

ec01100

Metabolic pathways

Orthology

K01522

bis(5'-adenosyl)-triphosphatase

K18424

ectonucleotide pyrophosphatase/phosphodiesterase family member 4

Genes

HSA:	2272(FHIT) 22875(ENPP4)

PTR:	462740(ENPP4) 747260(FHIT)

PPS:	100969396(ENPP4) 100985630(FHIT)

GGO:	101150582(ENPP4)

PON:	100172690(ENPP4) 100460961(FHIT)

NLE:	100587404(ENPP4) 100587886(FHIT)

MCC:	700974(FHIT) 703680(ENPP4)

MCF:	102115606(ENPP4) 102118172(FHIT)

CSAB:

103221421(ENPP4) 103227823(FHIT)

RRO:	104654204(ENPP4) 104671818(FHIT)

RBB:	108533431(ENPP4) 108543621(FHIT)

CJC:	100396966(FHIT) 100409106(ENPP4)

SBQ:	101035217(ENPP4) 101053087(FHIT)

MMU:	14198(Fhit) 224794(Enpp4)

MCAL:

110283825(Enpp4) 110309527(Fhit)

MPAH:

110325606(Fhit) 110335895(Enpp4)

RNO:	301261(Enpp4) 60398(Fhit)

MUN:	110552105(Enpp4) 110565012(Fhit)

CGE:	100755382(Fhit) 100763274(Enpp4)

NGI:	103729434(Fhit) 103744876(Enpp4)

HGL:	101720165(Fhit) 101721340(Enpp4)

CCAN:

109682010(Fhit) 109700331(Enpp4)

OCU:	100339399(ENPP4) 100356299(FHIT)

TUP:	102471540(ENPP4) 102472981(FHIT)

CFA:	100215999(FHIT) 481823(ENPP4)

VVP:	112909469(FHIT) 112914045(ENPP4)

AML:	100471537(ENPP4) 100481949(FHIT)

UMR:	103664039(ENPP4) 103674216(FHIT)

UAH:	113256508(FHIT) 113261238(ENPP4)

ORO:	101374240(ENPP4) 105758078(FHIT)

ELK:	111144098 111147834

FCA:	101082731(FHIT) 101089863(ENPP4)

PTG:	102968381(FHIT) 102971993(ENPP4)

PPAD:

109271699(ENPP4) 109279074(FHIT)

AJU:	106968830(FHIT) 106974001(ENPP4)

BTA:	538583(ENPP4) 692183(FHIT)

BOM:	102274093(ENPP4) 102283297(FHIT)

BIU:	109576333(FHIT) 109577240(ENPP4)

BBUB:

102395326(FHIT) 102409052(ENPP4)

CHX:	102181635(FHIT) 102182739(ENPP4)

OAS:	100307043(FHIT) 101119767(ENPP4)

SSC:	100738210(ENPP4) 102159722(FHIT)

CFR:	102519195(ENPP4) 102522783(FHIT)

CDK:	105089815(FHIT) 105101200(ENPP4)

BACU:

103003452(FHIT) 103013971(ENPP4)

LVE:	103075260(ENPP4) 103080293

OOR:	101275581(ENPP4) 105747905(FHIT)

DLE:	111174232(FHIT) 111178884(ENPP4)

PCAD:

102974384(ENPP4) 102995999(FHIT)

ECB:	100057165(FHIT) 100068264(ENPP4)

EPZ:	103550825(FHIT) 103565930(ENPP4)

EAI:	106828767(ENPP4) 106848673(FHIT)

MYB:	102251939 102257670(ENPP4) 102263006(FHIT)

MYD:	102752441(ENPP4) 102761500 102773714(FHIT)

MNA:	107536924(ENPP4)

HAI:	109382899(ENPP4) 109388237(FHIT)

DRO:	112301080(FHIT) 112302165(ENPP4)

PALE:

102883490(FHIT) 102886064(ENPP4)

RAY:	107504075(ENPP4) 107513488(FHIT)

MJV:	108395968(ENPP4) 108407555(FHIT)

LAV:	100654457(ENPP4) 100654588(FHIT)

TMU:	101346584 111819740

MDO:	100012154(ENPP4) 100016692(FHIT)

SHR:	100915775(ENPP4) 100923843(FHIT)

PCW:	110201683(FHIT) 110213505(ENPP4)

OAA:	100074241(FHIT) 100080631(ENPP4)

GGA:	416071(FHIT) 422055(ENPP4)

MGP:	100548000(FHIT) 100549970(ENPP4)

CJO:	107312463 107319940(FHIT)

NMEL:

110395834 110404621(FHIT)

APLA:

101790379(ENPP4) 101803330(FHIT)

ACYG:

106035488(FHIT) 106038201(ENPP4)

TGU:	100223655(FHIT) 100225551(ENPP4)

LSR:	110468946(ENPP4) 110470245 110470799(FHIT)

SCAN:

103817068(FHIT) 103821119(ENPP4)

GFR:	102041710(ENPP4) 102043890(FHIT)

FAB:	101806945(ENPP4) 101821344(FHIT)

PHI:	102101706(FHIT) 102114442(ENPP4)

PMAJ:

107201655(ENPP4) 107210320(FHIT)

CCAE:

111927416(ENPP4) 111935007(FHIT)

CCW:	104683340(FHIT) 104685380(ENPP4)

ETL:	114056821(FHIT) 114058848(ENPP4)

FPG:	101910385(FHIT) 101916372(ENPP4)

FCH:	102048519(FHIT) 102053071(ENPP4)

CLV:	102093137(FHIT) 102095285(ENPP4)

EGZ:	104127017(ENPP4) 104134788(FHIT)

NNI:	104014667(ENPP4) 104016909(FHIT)

ACUN:

113478042(ENPP4) 113484990(FHIT)

PADL:

103913208(ENPP4) 103921502(FHIT)

AAM:	106489564(FHIT) 106495208(ENPP4)

ASN:	102387455(ENPP4)

AMJ:	102559644(ENPP4) 102559919(FHIT)

PSS:	102451516(FHIT) 102456948(ENPP4)

CMY:	102936297(FHIT) 102944522(ENPP4)

CPIC:

101935928(ENPP4) 101938921(FHIT)

ACS:	100555583(enpp4) 100559518(fhit)

PVT:	110083229(ENPP4) 110087317(FHIT)

PBI:	103048266(ENPP4)

PMUR:

107284279 107286418(FHIT)

TSR:	106541938(FHIT) 106542806(ENPP4)

PMUA:

114591883(FHIT) 114600172(ENPP4)

GJA:	107113074(FHIT) 107122643(ENPP4)

XLA:	447221(enpp4.L) 495983(fhit.L) 496222

XTR:	448702(fhit) 550082(enpp4)

NPR:	108793024(FHIT) 108795529(ENPP4)

DRE:	393713(fhit) 550586(enpp4)

SRX:	107717235 107733460 107750995(fhit)

SANH:

107654163 107654179 107693088 107699359

SGH:	107552038 107571837(fhit) 107594078(enpp4)

CCAR:

109098834(fhit) 109107473 109108316

IPU:	108255098(fhit) 108270376(enpp4)

PHYP:

113538786(enpp4) 113539467(fhit)

AMEX:

103039441(fhit) 103041977(enpp4)

EEE:	113572642(enpp4) 113583908(fhit)

TRU:	101074368(fhit) 101080124(enpp4)

TNG:	GSTEN00005466G001 GSTEN00026671G001

LCO:	104925342(enpp4)

NCC:

104952713

MZE:	101474098(fhit) 101482036(enpp4)

ONL:	100702722(fhit) 100709679(enpp4)

OLA:	101168684(enpp4)

XMA:	102232229(enpp4)

XCO:	114140773(enpp4)

PRET:

103476246(enpp4)

CVG:	107094121(enpp4)

NFU:	107381044(enpp4)

KMR:	108246498(enpp4)

ALIM:

106519125(enpp4)

AOCE:

111562796(enpp4) 111572842(fhit)

CSEM:

103381161 103389680(enpp4)

POV:	109639755(enpp4)

LCF:	108888910(fhit) 108891869(enpp4)

SDU:	111222741(enpp4) 111240319(fhit)

SLAL:

111645997(enpp4) 111661513(fhit)

HCQ:	109515032(enpp4) 109521654(fhit)

BPEC:

110153238(enpp4) 110154442

MALB:

109955718(enpp4)

SASA:

100196755(enpp4)

OTW:	112218987(fhit) 112261670(enpp4)

SALP:

111968153(fhit) 111968624(enpp4)

ELS:	105005604(enpp4) 105026846(fhit)

SFM:	108923422(fhit) 108929223(enpp4)

PKI:	111834568(fhit) 111837504(enpp4)

LCM:	102351069(ENPP4) 102354340(FHIT)

CMK:	103179762(fhit) 103184989(enpp4)

RTP:	109911950(enpp4) 109912164(fhit)

BFO:	118415893 118416866

CIN:

SPU:

APLC:

SKO:

DPA:

PMAC:

DPX:	DAPPUDRAFT_45778

PVM:	113810815 113822055 113824842

ISC:	IscW_ISCW020169

DPTE:

113790131 113792002

CSCU:

111626911

TSP:	Tsp_10950 Tsp_14826

LGI:	LOTGIDRAFT_116186

NVE:

EPA:

ADF:

AMIL:

PDAM:

SPIS:

DGT:	114516403 114516486 114520759

HMG:	100197208 100208713 101238147

AQU:

100635362

ATH:	AT5G58240(FHIT)

ALY:

9300634

CRB:

17876018

CSAT:

104726391 104735284 104761921

EUS:	EUTSA_v10014808mg

BRP:

103845250

BNA:	106420263 106426053

BOE:

RSZ:

THJ:

CPAP:

CIT:	102609440 102621441 102621732

CIC:	CICLE_v10005970mg CICLE_v10006524mg CICLE_v10006852mg

TCC:

18591119

GRA:

105777681

GHI:	107897060 107915004

GAB:

108465959

DZI:

111285811

EGR:	104441258 104441259

GMX:	100305764 100527670 100798834

GSJ:	114373447 114395050 114395355

PVU:	PHAVU_006G082400g PHAVU_006G082500g

VRA:	106775079 106775431

VAR:	108341840 108342601

VUN:	114186830 114186989

CCAJ:

109789182 109789188

MTR:	MTR_3g062940 MTR_3g062950 MTR_3g063030

CAM:	101489427 101489749

LJA:	Lj0g3v0054449.1(Lj0g3v0054449.1) Lj0g3v0054459.1(Lj0g3v0054459.1) Lj0g3v0054459.2(Lj0g3v0054459.2)

ADU:	107474236 107474258

AIP:	107637172 107637400

LANG:

109330309 109345185 109345186

FVE:	101309332 101310678

RCN:	112166946 112166947

PPER:

18773312

PMUM:

103318568

PAVI:

110750845

MDM:	103422756 114823872

PXB:	103949177 103963332 103967590

ZJU:

107411680

CSV:	101213613 101215130

CMO:	103490697 103490973

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:

MESC:

POP:	7464753 7494644

PEU:

105137636

JRE:	108986800 108989181

QSU:	112007211 112009525

VVI:

SLY:

SPEN:

SOT:

CANN:

NTA:	107791024 107832232

NSY:

NTO:

NAU:

INI:

SIND:

OEU:	111379986 111393724

HAN:	110873430 110897677

LSV:	111886654 111908447

CCAV:

112507363 112518167

DCR:	108192783 108203575

BVG:

104902682

SOE:

110785210

CQI:	110691947 110701997

NNU:

104610857

PSOM:

113313523 113314180 113323815

OSA:	4349630 4351353 4351354

DOSA:

Os11t0120600-00(Os11g0120600) Os11t0120725-00(Os11g0120725) Os12t0120200-01(Os12g0120200) Os12t0120400-01(Os12g0120400)

OBR:	102702815 102703430 102705774 102709226 102716261

BDI:	100827306 100835768

ATS:	109735590(LOC109735590) 109780620(LOC109780620)

SBI:

8074831

ZMA:

100279797

SITA:

101777241

PDA:	103705909 103717877

EGU:	105046045 105052342

MUS:	103970555 103970916

DCT:

110098352

PEQ:

110027311

AOF:

109830728

ATR:	18439023 18448541

SMO:	SELMODRAFT_104256 SELMODRAFT_85116

PPP:

112281357

CRE:	CHLREDRAFT_100573

VCN:	VOLCADRAFT_71460

CSL:	COCSUDRAFT_32950

APRO:

F751_2219

OLU:	OSTLU_14523

OTA:	OT_ostta03g01560

BPG:	Bathy12g02830

MIS:	MICPUN_50494 MICPUN_89181

MPP:	MICPUCDRAFT_33505 MICPUCDRAFT_59639

CME:	CYME_CMC141C

GSL:	Gasu_44050

SCE:	YDR305C(HNT2)

AGO:	AGOS_AAL053C

ERC:

Ecym_3204

KLA:	KLLA0_C10142g

LTH:	KLTH0F07414g

VPO:	Kpol_1005p3

ZRO:	ZYRO0C13970g

CGR:	CAGL0G04147g

NCS:	NCAS_0F02720(NCAS0F02720)

NDI:	NDAI_0C04190(NDAI0C04190)

TPF:	TPHA_0D01910(TPHA0D01910)

TBL:	TBLA_0C03440(TBLA0C03440)

TDL:	TDEL_0E03010(TDEL0E03010)

KAF:	KAFR_0E01280(KAFR0E01280)

PPA:	PAS_chr2-1_0146

DHA:	DEHA2G10296g

PIC:	PICST_56209(HNT2)

PGU:	PGUG_02782

SPAA:

SPAPADRAFT_62330

LEL:	LELG_02725

CAL:	CAALFM_C306340WA(HNT2)

CTP:	CTRG_02225 CTRG_02244

COT:	CORT_0C04250

CDU:	CD36_86130 CD36_86320

CTEN:

CANTEDRAFT_113819

YLI:	YALI0E32736g

CLU:	CLUG_03597

CLUS:

A9F13_01g05654

CAUR:

CJI97_000648

SLB:	AWJ20_1664(HNT2)

PKZ:	C5L36_0B11850

NCR:

NCU08293

NTE:	NEUTE1DRAFT78895(NEUTE1DRAFT_78895)

SMP:	SMAC_00924

TTT:	THITE_2115414

MTM:	MYCTH_104936

CTHR:

CTHT_0032930

MGR:

MGG_01517

TMN:	UCRPA7_468

SSCK:

SPSK_03556

FGR:	FGSG_09805

FPU:	FPSE_00837

FVR:	FVEG_06419

FOX:	FOXG_08253

NHE:	NECHADRAFT_91080

TRE:	TRIREDRAFT_2358

TRR:	M419DRAFT_71167

MAW:

MAC_06421

MAJ:

MAA_05053

CMT:

CCM_04282

PLJ:	VFPFJ_00892

VAL:	VDBG_08270

VDA:	VDAG_10249

CFJ:	CFIO01_09106

SAPO:

SAPIO_CDS7509

ELA:	UCREL1_5347

PFY:	PFICI_04674

SSL:	SS1G_01917

BFU:	BCIN_07g03480(Bchnt2)

MBE:

MBM_02940

PSCO:

LY89DRAFT_585833

GLZ:	GLAREA_03977 GLAREA_04629 GLAREA_05004

ANI:

AN6189.2

AFM:	AFUA_2G11700

ACT:	ACLA_070650

NFI:	NFIA_086940

AOR:	AO090026000478

AFV:	AFLA_134560

PCS:	Pc20g13780

PDP:	PDIP_16700

TMF:	PMAA_049470

TRG:	TRUGW13939_07606

CIM:	CIMG_13261(CIMG08138)

CPW:	CPC735_021690

PBL:	PAAG_11734(PAAG_03742)

PBN:	PADG_03245

URE:	UREG_02402

ABE:

ARB_06274

TVE:

TRV_06395

AJE:	HCAG_07176

BGH:	BDBG_00676

PNO:	SNOG_12586

PTE:

PTT_09294

BZE:	COCCADRAFT_87989

BSC:	COCSADRAFT_36151

BOR:	COCMIDRAFT_111247

AALT:

CC77DRAFT_1028817

ZTR:	MYCGRDRAFT_93237

PFJ:	MYCFIDRAFT_79853

BCOM:

BAUCODRAFT_37424

NPA:	UCRNP2_9875

TML:	GSTUM_00006223001

SPO:	SPCC4G3.02(aph1)

CNE:

CNH01930

CNB:

CNBL1930

CGI:	CGB_L2310C

TMS:	TREMEDRAFT_31446

TASA:

A1Q1_03850

TVS:	TRAVEDRAFT_42275

DSQ:	DICSQDRAFT_95000

PCO:	PHACADRAFT_214815

SHS:	STEHIDRAFT_62968

HIR:	HETIRDRAFT_306873

PSQ:	PUNSTDRAFT_110025

ADL:	AURDEDRAFT_79269

FME:	FOMMEDRAFT_95734

GTR:	GLOTRDRAFT_7624

LBC:	LACBIDRAFT_301287

MRR:	Moror_4786

CCI:	CC1G_01223

SCM:	SCHCODRAFT_230453

SLA:	SERLADRAFT_477081

WSE:	WALSEDRAFT_43052

WIC:	J056_002776

PFP:	PFL1_06241

PGR:	PGTG_00158

MLR:	MELLADRAFT_93393

ECU:	ECU10_0480

EIN:	Eint_100420

EHE:	EHEL_100480

ERO:	EROM_100350

NCE:	NCER_100351

DDI:	DDB_G0274257

DPP:	DICPUDRAFT_160396

DFA:

DFA_04551

ACAN:

ACA1_127880 ACA1_150090

PFA:	PF3D7_1436900

PYO:	PY17X_0614400

PCB:	PCHAS_061360(PC000777.04.0)

PBE:	PBANKA_0611900

PKN:	PKH_131250

PVX:	PVX_084695

PCY:	PCYB_132210

TAN:

TA05075

TPV:

TP03_0531

TOT:	TOT_030000913

BEQ:	BEWA_012030

BBO:	BBOV_I004910(19.m02241)

TGO:	TGME49_225420 TGME49_320120

TET:	TTHERM_00378790 TTHERM_00637570

PTM:	GSPATT00020685001 GSPATT00038159001

SMIN:

v1.2.010824.t1(symbB.v1.2.010824.t1)

PTI:	PHATR_10458

FCY:	FRACYDRAFT_197356 FRACYDRAFT_201468

TPS:	THAPSDRAFT_283

NGD:	NGA_0688800(FHIT)

AAF:	AURANDRAFT_7876

PSOJ:

PHYSODRAFT_496321

SPAR:

SPRG_11940

EHX:	EMIHUDRAFT_58735 EMIHUDRAFT_63025

GTT:	GUITHDRAFT_73962

TBR:	Tb927.8.2980

TBG:	TbgDal_VIII2660

NGR:	NAEGRDRAFT_5292 NAEGRDRAFT_63445

TVA:	TVAG_468310

KBA:	A0U89_01885

ASD:

AS9A_1838

REY:

O5Y_23920

RHW:	BFN03_03820

DTM:	BJL86_1741

JTE:	ASJ30_09715

JLI:	EXU32_04725

KDI:	Krodi_0287

DOD:	DCS32_10760

» show all

Reference

1 [PMID:6309793]

Authors

Jakubowski H, Guranowski A.

Title

Enzymes hydrolyzing ApppA and/or AppppA in higher plants. Purification and some properties of diadenosine triphosphatase, diadenosine tetraphosphatase, and phosphodiesterase from yellow lupin (Lupinus luteus) seeds.

Journal

J Biol Chem 258:9982-9 (1983)

Reference

2 [PMID:196848]

Authors

Sillero MA, Villalba R, Moreno A, Quintanilla M, Lobaton CD, Sillero A.

Title

Dinucleosidetriphosphatase from rat liver. Purification and properties.

Journal

Eur J Biochem 76:331-7 (1977)
DOI:10.1111/j.1432-1033.1977.tb11600.x

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