| Entry |
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| Name |
acetoacetate decarboxylase;
acetoacetic acid decarboxylase;
acetoacetate carboxy-lyase
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| Class |
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
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| Sysname |
acetoacetate carboxy-lyase (acetone-forming)
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| Reaction(IUBMB) |
acetoacetate + H+ = acetone + CO2 [RN: R01366]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| History |
EC 4.1.1.4 created 1961
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| Pathway |
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| Orthology |
| K01574 | acetoacetate decarboxylase |
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| Genes |
| LSH: | CAB17_07330 CAB17_13380 |
| LJR: | NCTC11533_02131(adc) |
| LCJ: | NCTC11976_01373(adc) |
| LWA: | SAMEA4504053_0998(adc) |
| LSS: | NCTC12082_00433(adc) |
| LADL: | NCTC12735_00965(adc) |
| LANT: | TUM19329_28970(adc) |
| FTD: | AS84_1732 AS84_221(adc) |
| BVI: | Bcep1808_3777 Bcep1808_4583 |
| BUR: | Bcep18194_B1397 Bcep18194_B3166 |
| BAC: | BamMC406_3126 BamMC406_5563 |
| BCEP: | APZ15_24935 APZ15_36175 |
| BPYR: | ABD05_21330 ABD05_30610 |
| BLAT: | WK25_15965 WK25_19575 |
| BSTG: | WT74_20460 WT74_24130 |
| BAEN: | L3V59_29415 L3V59_29795 |
| BURK: | DM992_22035 DM992_26110 DM992_34560 |
| BURT: | BTHE68_57170(adc_1) BTHE68_59520(adc_2) |
| BPY: | Bphyt_1567 Bphyt_2412 |
| BUZ: | AYM40_23020 AYM40_28035 |
| BCAI: | K788_0000336 K788_0005690 |
| PHS: | C2L64_26230 C2L64_27150 |
| PTER: | C2L65_22200 C2L65_28160 |
| PACP: | FAZ97_23835 FAZ97_28595 |
| PEW: | KZJ38_25620 KZJ38_33460 |
| PDIO: | PDMSB3_0240.1 PDMSB3_1576 |
| PBRY: | NDK50_06825 NDK50_12885 |
| PSAA: | QEN71_09075 QEN71_14990 |
| PBON: | QS306_11000 QS306_11005 |
| PPAI: | E1956_25205 E1956_31885 E1956_32480 |
| PLAD: | PPGU16_35880(adc_1) PPGU16_45110(adc_2) |
| PAZZ: | PBP221_44560 PBP221_53820 |
| CABK: | NK8_55120 NK8_56950 |
| TVL: | FAZ95_06535 FAZ95_24700 FAZ95_27330 |
| TCAR: | U0034_12365 U0034_24475 |
| BTRM: | SAMEA390648701655(adc) |
| MLO: | mll5917 mlr2399 mlr3634 |
| MLN: | A9174_07425 A9174_32420 |
| MESP: | C1M53_17115 C1M53_17410 |
| MJR: | EB229_07635 EB229_33140 |
| MERD: | EB233_07550 EB233_30785 |
| MOH: | IHQ72_12815 IHQ72_12890 IHQ72_13400 IHQ72_34110 |
| RII: | FFM53_006555 FFM53_034345 |
| BJA: | bll7763(bll7763) blr3945(blr3945) blr7028(blr7028) |
| BJU: | BJ6T_16150 BJ6T_58910 BJ6T_62570 |
| BJP: | RN69_07975 RN69_30325 |
| BRAD: | BF49_0522 BF49_1107 |
| BRK: | CWS35_01220 CWS35_27820 |
| BOT: | CIT37_17685 CIT37_22400 CIT37_34260 CIT37_35815 |
| BEL: | BE61_63130 BE61_85850 BE61_87570 |
| BSEP: | HAP48_0021020 HAP48_0022790 HAP48_0034650 |
| BQB: | J4P68_0003745 J4P68_0013070 J4P68_0017465 |
| BBAN: | J4G43_007405 J4G43_019855 J4G43_022100 J4G43_040910 |
| BCAN: | BcanWSM471_02610 BcanWSM471_17100 |
| BAUT: | QA635_25320 QA635_37080 |
| BBRA: | QA636_08045 QA636_26265 QA636_38170 QA636_38900 |
| BGK: | IC762_05495 IC762_15190 |
| BCOU: | IC761_19110 IC761_21430 |
| BPAH: | QA639_18755 QA639_36590 |
| BROS: | QUH67_03765 QUH67_04900 QUH67_30925 |
| BRAA: | NL528_07580 NL528_13895 NL528_13915 |
| RHOR: | ONR75_05825 ONR75_23345 |
| VGO: | GJW-30_1_03383(adc_1) GJW-30_1_03970(adc_2) |
| TRB: | HB776_20345 HB776_20960 |
| TARD: | RSO67_14000 RSO67_14750 |
| BOF: | FQV39_15580 FQV39_29260 |
| XDI: | EZH22_06805 EZH22_22120 |
| MAQU: | Maq22A_2p40725 Maq22A_c24380(adc) |
| MOC: | BB934_02595 BB934_11530 BB934_31395 BB934_36525 |
| MLD: | U0023_21760 U0023_31505 |
| MTUN: | MTUNDRAET4_2027(adc) |
| MEDK: | QEV83_03880 QEV83_14865 |
| RHZ: | RHPLAN_16330 RHPLAN_31430 |
| PSTG: | E8M01_28145 E8M01_28150 |
| BLAS: | BSY18_3376 BSY18_3377 |
| BFW: | B5J99_07755 B5J99_07760 |
| HTQ: | FRZ44_16710(adc2) FRZ44_20890 |
| NCM: | QNK12_15245 QNK12_15255 |
| PPM: | PPSC2_06055(adc1) PPSC2_12620(adc3) |
| PPO: | PPM_1145(adc1) PPM_2419(adc3) |
| PPOY: | RE92_05830 RE92_24155 |
| PLZH: | C0638_01760 C0638_20485 |
| SCT: | SCAT_p0752(adc) SCAT_p1328(adc) |
| SCY: | SCATT_p03950 SCATT_p09870 |
| ARHD: | VSH64_20685 VSH64_44775 |
| ACAB: | QRX50_00465 QRX50_24960 |
| AMYD: | K1T34_00465 K1T34_25590 |
| KUT: | JJ691_21780(adc_1) JJ691_45660(adc_3) |
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| Reference |
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| Authors |
Davies R. |
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| Title |
Studies on the acetone-butanol fermentation: 4. Acetoacetic acid decarboxylase of Cl. acetobutylicum (BY). |
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| Journal |
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| Reference |
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| Authors |
Zerner B, Coutts SM, Lederer F, Waters HH, Westheimer FH. |
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| Title |
Acetoacetate decarboxylase. Preparation of the enzyme. |
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| Journal |
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| Reference |
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| Authors |
Ho MC, Menetret JF, Tsuruta H, Allen KN |
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| Title |
The origin of the electrostatic perturbation in acetoacetate decarboxylase. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 4.1.1.4 |
| ExPASy - ENZYME nomenclature database: | 4.1.1.4 |
| BRENDA, the Enzyme Database: | 4.1.1.4 |
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| LinkDB |
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