| Entry |
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| Name |
acetoacetate decarboxylase;
acetoacetic acid decarboxylase;
acetoacetate carboxy-lyase
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| Class |
Lyases;
Carbon-carbon lyases;
Carboxy-lyases
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| Sysname |
acetoacetate carboxy-lyase (acetone-forming)
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| Reaction(IUBMB) |
acetoacetate + H+ = acetone + CO2 [RN: R01366]
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| Reaction(KEGG) |
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| Substrate |
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| Product |
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| History |
EC 4.1.1.4 created 1961
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| Pathway |
| ec00072 | Synthesis and degradation of ketone bodies |
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| Orthology |
| K01574 | acetoacetate decarboxylase |
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| Genes |
» show all
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| Reference |
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| Authors |
Davies R. |
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| Title |
Studies on the acetone-butanol fermentation: 4. Acetoacetic acid decarboxylase of Cl. acetobutylicum (BY). |
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| Journal |
Biochem J 37:230-8 (1943) |
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| Reference |
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| Authors |
Zerner B, Coutts SM, Lederer F, Waters HH, Westheimer FH. |
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| Title |
Acetoacetate decarboxylase. Preparation of the enzyme. |
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| Journal |
Biochemistry 5:813-6 (1966) |
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| Reference |
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| Authors |
Ho MC, Menetret JF, Tsuruta H, Allen KN |
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| Title |
The origin of the electrostatic perturbation in acetoacetate decarboxylase. |
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| Journal |
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| Other DBs |
| ExplorEnz - The Enzyme Database: | 4.1.1.4 |
| ExPASy - ENZYME nomenclature database: | 4.1.1.4 |
| BRENDA, the Enzyme Database: | 4.1.1.4 |
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| LinkDB |
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