ENZYME: 4.2.3.210
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Entry
EC 4.2.3.210 Enzyme
Name
lydicene synthase;
StlTC
Class
Lyases;
Carbon-oxygen lyases;
Acting on phosphates
BRITE hierarchy
Sysname
geranylgerany-diphosphate diphosphate-lyase (lydicene-forming)
Reaction(IUBMB)
geranylgeranyl diphosphate = lydicene + diphosphate [RN:
R13103
]
Reaction(KEGG)
R13103
Reaction
Substrate
geranylgeranyl diphosphate [CPD:
C00353
]
Product
lydicene [CPD:
C22616
];
diphosphate [CPD:
C00013
]
Comment
Requires Mg2+. Characterized from the bacterium Streptomyces lydicus.
History
EC 4.2.3.210 created 2022
Orthology
K26354
lydicene synthase
Genes
SLD
:
T261_7018
Taxonomy
Reference
1 [PMID:
28371074
]
Authors
Yang YL, Zhang S, Ma K, Xu Y, Tao Q, Chen Y, Chen J, Guo S, Ren J, Wang W, Tao Y, Yin WB, Liu H.
Title
Discovery and Characterization of a New Family of Diterpene Cyclases in Bacteria and Fungi.
Journal
Angew Chem Int Ed Engl 56:4749-4752 (2017)
DOI:
10.1002/anie.201700565
Sequence
[sld:
T261_7018
]
Other DBs
ExplorEnz - The Enzyme Database:
4.2.3.210
IUBMB Enzyme Nomenclature:
4.2.3.210
ExPASy - ENZYME nomenclature database:
4.2.3.210
BRENDA, the Enzyme Database:
4.2.3.210
LinkDB
All DBs
DBGET
integrated database retrieval system