Equus caballus (horse): 100072444
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Entry
100072444 CDS
T01058
Symbol
NRG2
Name
(RefSeq) LOW QUALITY PROTEIN: pro-neuregulin-2, membrane-bound isoform
KO
K05456
neuregulin 2
Organism
ecb
Equus caballus (horse)
Pathway
ecb01521
EGFR tyrosine kinase inhibitor resistance
ecb04012
ErbB signaling pathway
ecb05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
ecb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100072444 (NRG2)
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
100072444 (NRG2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100072444 (NRG2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
ecb04052
]
100072444 (NRG2)
Cytokines and neuropeptides [BR:
ecb04052
]
Cytokines
Growth factors (RTK binding)
100072444 (NRG2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Neuregulin
I-set
Ig_3
ig
Ig_2
Ig_6
EGF
V-set
C2-set_2
DUF3169
DUF6377
EGF_2
Motif
Other DBs
NCBI-GeneID:
100072444
NCBI-ProteinID:
XP_023473351
LinkDB
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Position
14:36055154..36238896
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AA seq
847 aa
AA seq
DB search
MRQVCCSALSPPPLEKAPCISYSDSSSSSSSSSSSSSSERSSSSSESSSSRSSNSSISRP
AAPPEPRPPQQPQPRNPAARRAAARSRAAAAGGMRRDPAPGFSMLLFGVSLACYSPSLKS
VQDQAYKAPVVVEGKVQGLAPAGGSSSNSTREPPASGRVALVKVLDKWPLRSGGLQREQV
ISVGSCAPLERNQRYIFFLEPTEQPLVFKTAFAPLDTNGKNLKKEVGKILCTDCATRPKL
KKMKSQTGQVGEKQSLKCEAAAGNPQPSYRWFKDGKELNRSRDIRIKYGNGRKNSRLQFN
KVKVEDAGEYVCEAENILGKDTVRGRLHVNSVSTTLSSWSGHARKCNETAKSYCVNGGVC
YYIEGINQLSCKCPVGYTGDRCQQFAMVNFSKHLGFELKEAEELYQKRVLTITGICVALL
VVGIVCVVAYCKTKKQRKQMHNHLRQNMCPAHQNRSLANGPSHPRLDPEEIQMADYISKN
VPATDHVIRRETETTFSGSHSCSPSHHCSTATPTSSHRHESHTWSLERSESLTSDSQSGI
MLSSVGTSKCNSPACVEARARRAAAYTLEERRRAAVPPYHDSIDSLRDSPHSERYVSALT
TPARLSPVDFHYSLATQVPTFEITSPNSAHAVSLPPAAPINYRLAEQQPLLRHPTPPGPG
PGCGPSADMQRSYDSYYYPAAGPGPRRGACALGGSLGSLPASPFRXXXXXXXQECAPPPP
PPRPRARGASRRTSAGPRRWRRSRLNGLAAQRARAARDSLSLSSGSGGGSASASDDDADD
ADGALAAESTPFLGLRAAHDALRSDSPPLCPAADSRTYYSLDSHSTRASSRHSRGPPPRA
TQDSAPL
NT seq
2544 nt
NT seq
+upstream
nt +downstream
nt
atgcggcaggtttgctgctcagcgctgtcgccgccgccactggagaaggctccgtgcatc
agctacagcgacagcagcagcagcagcagcagcagcagcagcagcagcagcagcgagagg
agcagcagcagcagcgagagcagcagcagcaggagcagcaacagcagcatctcccgtccc
gctgcgcccccagagccgcggccgccgcaacagccgcagccccgcaaccccgcagcccgg
agagccgccgcccgctcgcgagccgcagccgccggcggcatgaggcgcgacccggccccc
ggcttctccatgctgctcttcggtgtgtcgctcgcctgctactcgcctagcctcaagtcg
gtgcaggaccaggcgtacaaggcacccgtggtggtggagggcaaggtacaggggctggcc
ccagccggcggctccagctccaacagcacccgcgagccgcccgcctcgggtcgggtggcg
ctggtgaaggtgctggacaagtggccgctccggagcggggggctgcagcgcgagcaggtg
atcagcgtgggctcctgcgcgccgcttgaaaggaaccagcgctacatctttttcctggaa
cccacggagcagcccttagtctttaagacggcctttgcacccctcgataccaacggcaaa
aacctcaagaaagaggtgggcaagatcctgtgcactgactgcgccacccggcccaagcta
aagaagatgaagagccagacgggacaagtgggtgagaaacaatcgctgaagtgcgaggca
gctgctgggaacccccagccctcctaccgctggttcaaggatggcaaggaactcaaccgc
agccgcgacatccgcatcaagtatggcaatggcagaaagaactcacgactacagttcaac
aaggtgaaggtggaggatgctggggaatatgtctgcgaggcggagaacatcctggggaag
gacacagtccggggccggctccacgtcaacagcgtgagcaccactctgtcctcctggtcg
gggcatgcccggaagtgcaacgagacagccaagtcctattgtgtcaatggaggcgtctgc
tactacatcgagggcatcaaccaactctcctgcaagtgtcctgtgggatacaccggggac
aggtgtcagcagttcgcaatggtcaacttctccaagcaccttggatttgaactaaaggaa
gccgaggagctgtaccagaagagggtcctgactatcaccggtatctgcgtggctttgctg
gtcgtgggcatcgtctgcgtggtcgcctactgcaagaccaaaaaacagcggaagcagatg
cacaatcacctccggcagaacatgtgcccagcccaccagaaccggagcttggccaacggg
cccagccacccccggctggaccctgaggagatccagatggcagattacatctccaagaac
gtaccagccacagaccatgtcatccggagggaaactgagaccaccttctccgggagccac
tcctgttctccttctcaccactgctccacagccacacccacctccagccacaggcatgag
agccacacgtggagcctggaacgttctgagagcctgacctctgactcccagtcaggcatc
atgctgtcatcagtgggcaccagcaagtgcaacagcccagcgtgcgtggaggcccgggcg
cggcgggcggcagcctacaccctggaggagcggcgcagggctgccgtgcccccttaccat
gactccatagactccctgcgtgattccccacacagcgagaggtacgtgtcggccctgacc
acgcccgcgcgcctctctcccgtggacttccactactcgctagccacgcaggtgccgact
ttcgagatcacgtcccctaactcggcgcacgccgtgtcgctgccgcccgccgcgcccatc
aactaccgcctggcggagcagcagccgctcctgcggcacccgacgccccccggccccggg
cctggatgcgggcccagcgccgacatgcagcgcagctacgacagctactactaccccgca
gcggggccggggccgcgacgcggggcctgcgcgctcggcggcagcctgggcagcctgccc
gccagccccttccgnnnnnnnnnnnnnnnnnnnnnncaggagtgcgcgcccccgccgccg
ccgccgcggccgcgcgcccgcggcgcgtcccgcaggacgtcggcggggccccggcgctgg
cgccgctcgcgcctcaacgggctggcggcgcagcgcgcacgcgcggcgcgggactcgctg
tcgctgagcagcggctcaggagggggctcggcttcggcctccgacgacgacgcggacgac
gcggacggggcgctggcggccgagagcacgcctttcctcggcctgcgcgcggcgcacgac
gcgctgcgctcggactcgccgccgctgtgcccggcggccgacagcaggacttactactcc
ctggacagccacagcacgcgggccagcagcagacacagccgcgggccgcccccgcgggcc
acgcaggactcggcgccgctctag
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