Escherichia coli O127 H6 E2348/69 (EPEC): E2348C_0091
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Entry
E2348C_0091 CDS
T00796
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide: D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ecg
Escherichia coli O127:H6 E2348/69 (EPEC)
Pathway
ecg00300
Lysine biosynthesis
ecg00550
Peptidoglycan biosynthesis
ecg01100
Metabolic pathways
ecg01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ecg00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
E2348C_0091 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
E2348C_0091 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
E2348C_0091 (murF)
Enzymes [BR:
ecg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
E2348C_0091 (murF)
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Paralog
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
CAS07639
UniProt:
B7UID6
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Position
100767..102125
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AA seq
452 aa
AA seq
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MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFAGQAKAG
GAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS
PNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATL
DAIKAGLANLKAVPGRLFPIKLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGD
MAELGAESEACHVQVGEAAKAAGIDCVLSVGKQSHAISTASGVGEHFSDKTALIARLKSL
IAEQQVITILVKGSRSAAMEEVVRALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcgtaacccttagccaacttaccgatattctcaacggtgaactgcaaggtgca
gatattacccttgatgctgtaaccactgacacgcgaaaactgacgccgggctgcctgttt
gttgccctgaaaggcgaacgtttcgatgctcatgattttgccggccaggcgaaagctggc
ggcgcaggcgcactactggttagccgtccgctggatattgatctgccgcagttaatcgtc
aaggatacgcgtctggcgtttggtgaactggctgcatgggttcgccagcaagttccggcg
cgcgtggttgctctgacaggttcctccggcaaaacctccgttaaagagatgacggcggca
attttaagccagtgcggcaacacactttatacggcaggcaatctcaataacgacatcggt
gtaccgatgacgctgttgcgcttaacgccggaatacgattacgcagttattgaacttggc
gcgaaccatcagggtgaaattgcctggactgtgagtctgactcgcccggaagcggcgctg
gtcaacaacctggcagcggcgcatctggaaggttttggctcgcttgcgggtgtcgcgaaa
gcgaaaggtgaaatctttagcggcctgccggaaaacggtatcgccattatgaacgccgac
aacaacgactggttgaactggcagagcgtaattggctcacgcaaagtgtggcgtttctca
cctaatgccgccaacagcgatttcaccgccaccaatatccatgtaacctcgcacggtacg
gaatttaccctgcaaaccccaacaggtagcgtcgatgttctgctgccgttgccggggcgt
cacaatattgcgaatgcgctggcagccgctgcgctctccatgtccgtgggcgcaacgctt
gatgctatcaaagcggggctggcaaatctgaaagctgttccaggccgtctgttccccata
aaactggcagaaaaccagttgctgctcgatgactcctacaacgccaatgtcggttcaatg
accgccgctgttcaggttctggctgaaatgccgggctaccgcgtgctggtggtgggcgat
atggcggaactgggcgctgaaagcgaagcctgccatgtacaggtgggcgaagcggcaaaa
gctgctggtattgactgcgtgttaagtgtgggtaaacaaagccatgctatcagcactgcc
agcggcgttggcgaacatttttccgataaaactgcgcttatcgcgcgtcttaaatcactg
attgctgagcaacaggtaattacgattttagttaagggttcacgtagtgctgccatggaa
gaggtagtacgcgctttacaggagaatgggacatgttag
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