Gracilinanus agilis (agile gracile opossum): 123250672
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Entry
123250672 CDS
T07702
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12 isoform X1
KO
K04441
p38 MAP kinase [EC:
2.7.11.24
]
Organism
gas
Gracilinanus agilis (agile gracile opossum)
Pathway
gas01522
Endocrine resistance
gas04010
MAPK signaling pathway
gas04015
Rap1 signaling pathway
gas04068
FoxO signaling pathway
gas04071
Sphingolipid signaling pathway
gas04114
Oocyte meiosis
gas04148
Efferocytosis
gas04218
Cellular senescence
gas04261
Adrenergic signaling in cardiomyocytes
gas04370
VEGF signaling pathway
gas04380
Osteoclast differentiation
gas04550
Signaling pathways regulating pluripotency of stem cells
gas04611
Platelet activation
gas04613
Neutrophil extracellular trap formation
gas04620
Toll-like receptor signaling pathway
gas04621
NOD-like receptor signaling pathway
gas04622
RIG-I-like receptor signaling pathway
gas04625
C-type lectin receptor signaling pathway
gas04657
IL-17 signaling pathway
gas04658
Th1 and Th2 cell differentiation
gas04659
Th17 cell differentiation
gas04660
T cell receptor signaling pathway
gas04664
Fc epsilon RI signaling pathway
gas04668
TNF signaling pathway
gas04670
Leukocyte transendothelial migration
gas04714
Thermogenesis
gas04722
Neurotrophin signaling pathway
gas04723
Retrograde endocannabinoid signaling
gas04728
Dopaminergic synapse
gas04750
Inflammatory mediator regulation of TRP channels
gas04912
GnRH signaling pathway
gas04914
Progesterone-mediated oocyte maturation
gas04917
Prolactin signaling pathway
gas04926
Relaxin signaling pathway
gas04932
Non-alcoholic fatty liver disease
gas04933
AGE-RAGE signaling pathway in diabetic complications
gas04935
Growth hormone synthesis, secretion and action
gas04936
Alcoholic liver disease
gas05014
Amyotrophic lateral sclerosis
gas05020
Prion disease
gas05022
Pathways of neurodegeneration - multiple diseases
gas05132
Salmonella infection
gas05133
Pertussis
gas05135
Yersinia infection
gas05140
Leishmaniasis
gas05142
Chagas disease
gas05145
Toxoplasmosis
gas05152
Tuberculosis
gas05161
Hepatitis B
gas05163
Human cytomegalovirus infection
gas05167
Kaposi sarcoma-associated herpesvirus infection
gas05169
Epstein-Barr virus infection
gas05170
Human immunodeficiency virus 1 infection
gas05171
Coronavirus disease - COVID-19
gas05205
Proteoglycans in cancer
gas05208
Chemical carcinogenesis - reactive oxygen species
gas05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
gas05415
Diabetic cardiomyopathy
gas05417
Lipid and atherosclerosis
gas05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
gas00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123250672 (MAPK12)
04015 Rap1 signaling pathway
123250672 (MAPK12)
04370 VEGF signaling pathway
123250672 (MAPK12)
04668 TNF signaling pathway
123250672 (MAPK12)
04068 FoxO signaling pathway
123250672 (MAPK12)
04071 Sphingolipid signaling pathway
123250672 (MAPK12)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
123250672 (MAPK12)
09143 Cell growth and death
04114 Oocyte meiosis
123250672 (MAPK12)
04218 Cellular senescence
123250672 (MAPK12)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
123250672 (MAPK12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
123250672 (MAPK12)
04613 Neutrophil extracellular trap formation
123250672 (MAPK12)
04620 Toll-like receptor signaling pathway
123250672 (MAPK12)
04621 NOD-like receptor signaling pathway
123250672 (MAPK12)
04622 RIG-I-like receptor signaling pathway
123250672 (MAPK12)
04625 C-type lectin receptor signaling pathway
123250672 (MAPK12)
04660 T cell receptor signaling pathway
123250672 (MAPK12)
04658 Th1 and Th2 cell differentiation
123250672 (MAPK12)
04659 Th17 cell differentiation
123250672 (MAPK12)
04657 IL-17 signaling pathway
123250672 (MAPK12)
04664 Fc epsilon RI signaling pathway
123250672 (MAPK12)
04670 Leukocyte transendothelial migration
123250672 (MAPK12)
09152 Endocrine system
04912 GnRH signaling pathway
123250672 (MAPK12)
04914 Progesterone-mediated oocyte maturation
123250672 (MAPK12)
04917 Prolactin signaling pathway
123250672 (MAPK12)
04926 Relaxin signaling pathway
123250672 (MAPK12)
04935 Growth hormone synthesis, secretion and action
123250672 (MAPK12)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
123250672 (MAPK12)
09156 Nervous system
04728 Dopaminergic synapse
123250672 (MAPK12)
04723 Retrograde endocannabinoid signaling
123250672 (MAPK12)
04722 Neurotrophin signaling pathway
123250672 (MAPK12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
123250672 (MAPK12)
09158 Development and regeneration
04380 Osteoclast differentiation
123250672 (MAPK12)
09159 Environmental adaptation
04714 Thermogenesis
123250672 (MAPK12)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
123250672 (MAPK12)
05208 Chemical carcinogenesis - reactive oxygen species
123250672 (MAPK12)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
123250672 (MAPK12)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
123250672 (MAPK12)
05161 Hepatitis B
123250672 (MAPK12)
05171 Coronavirus disease - COVID-19
123250672 (MAPK12)
05163 Human cytomegalovirus infection
123250672 (MAPK12)
05167 Kaposi sarcoma-associated herpesvirus infection
123250672 (MAPK12)
05169 Epstein-Barr virus infection
123250672 (MAPK12)
09171 Infectious disease: bacterial
05132 Salmonella infection
123250672 (MAPK12)
05135 Yersinia infection
123250672 (MAPK12)
05133 Pertussis
123250672 (MAPK12)
05152 Tuberculosis
123250672 (MAPK12)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
123250672 (MAPK12)
05140 Leishmaniasis
123250672 (MAPK12)
05142 Chagas disease
123250672 (MAPK12)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
123250672 (MAPK12)
05020 Prion disease
123250672 (MAPK12)
05022 Pathways of neurodegeneration - multiple diseases
123250672 (MAPK12)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
123250672 (MAPK12)
05418 Fluid shear stress and atherosclerosis
123250672 (MAPK12)
05415 Diabetic cardiomyopathy
123250672 (MAPK12)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
123250672 (MAPK12)
04932 Non-alcoholic fatty liver disease
123250672 (MAPK12)
04933 AGE-RAGE signaling pathway in diabetic complications
123250672 (MAPK12)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
123250672 (MAPK12)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
gas01001
]
123250672 (MAPK12)
Enzymes [BR:
gas01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
123250672 (MAPK12)
Protein kinases [BR:
gas01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
123250672 (MAPK12)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
RIO1
APH
Kdo
Kinase-like
Haspin_kinase
UvrD_C
FTA2
Motif
Other DBs
NCBI-GeneID:
123250672
NCBI-ProteinID:
XP_044535799
LinkDB
All DBs
Position
5:complement(305863268..305881714)
Genome browser
AA seq
349 aa
AA seq
DB search
MSSPPPPRKGFYRQEVTKTAWEVRELYRDLQPVGSGAYGAVCSAIDSRTGTKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDDTLDDFTDFYLVMPFMGTDLSKLM
KHEQLSDDRIQFLVYQILRGLKYIHAAGIVHRDLKPGNLAVNEDCELKILDFGLARQTDS
EMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKILFKGSDHLDQLMEIMK
VTGTPPPEFVQRLQSQDAKNYMENLPELEKKDFASILKNAPPLAVNLLEKMLVLDAEKRV
TAAEALTHPYFETVHESEEEPKAQLYDDSFDDVDRTLEEWKRESWPSMP
NT seq
1050 nt
NT seq
+upstream
nt +downstream
nt
atgagttcccctccgcccccccggaagggcttttaccggcaggaggtcactaagacagct
tgggaggtgcgggaactctaccgcgacctgcagcccgtgggctctggggcttacggggcc
gtgtgctcggccattgacagcaggaccggcaccaaggtggccatcaagaagctgtaccgt
cccttccagtcggagctgttcgccaagcgcgcctaccgggagctgcggctgctcaaacac
atgcgccacgagaacgtgattggcctactggatgtcttcaccccggatgacacactggat
gacttcacagacttttacctggtcatgccgttcatgggcaccgatctcagcaagctgatg
aaacatgagcagctcagcgatgaccggatccagttcttggtttaccagattcttcggggg
ctcaagtacatccatgctgctggcatcgtccacagggatctcaaacccggtaacctggca
gtgaatgaggactgtgagctgaagattctggactttggcctggccagacagacagacagt
gagatgactggctacgtggtgaccagatggtaccgggcacctgaggtcatcctcaactgg
atgcgttacacacagacagtggacatctggtctgtgggctgcatcatggcagagatgatc
actggaaagatccttttcaaagggagtgaccacctggaccagctgatggagatcatgaag
gtgacggggacacctccccccgagtttgtgcagcgcctccagagtcaggatgccaagaac
tacatggagaatctcccagagctggagaagaaggactttgcctccatcctgaagaacgcg
ccccccctggctgtgaacctgctcgagaagatgttggtactggatgccgagaagcgagtg
acagctgccgaggcgctgactcacccctactttgagactgtgcatgaatccgaggaggag
cccaaggcccagctctacgatgactccttcgacgacgttgaccggaccttggaggagtgg
aaacgtgagtcctggccttccatgccctga
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