Gallus gallus (chicken): 420078
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Entry
420078 CDS
T01006
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
gga
Gallus gallus (chicken)
Pathway
gga00310
Lysine degradation
gga01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
gga00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
420078 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
gga03036
]
420078 (DOT1L)
Enzymes [BR:
gga01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
420078 (DOT1L)
Chromosome and associated proteins [BR:
gga03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
420078 (DOT1L)
HMT complexes
Dot1-containing complex
420078 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
420078
NCBI-ProteinID:
XP_015155350
CGNC:
549
Ensembl:
ENSGALG00000000843
LinkDB
All DBs
Position
28:complement(2124859..2183605)
Genome browser
AA seq
1734 aa
AA seq
DB search
MGERLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVQ
ENKDSGAEEEKAGANAVKKPSPSKARKKKLSKKGRKMAGRKRGRPKKMNTANTERKTKKN
QTALELLHAQTVSQTSSSSPQDAYKSPHSPYYQLPPKVQRHSSNQLLVTPTPPALQKLLD
SFKIQYMQFMAYMKTPQYKASLQQLLEQEKEKNAQLLGTAQQLFTHCQAQKEEIKRLFQQ
KLDELGVKALTYNDLIQAQKEISAHNQQLKEQTKQLEKDNSELRNQSLQLLKARCEELKL
DWSTLSLENLLKEKQALKNQISEKQKHCLELQISIVELEKSQRQQELMQLKSYTPSDESL
SVQLRNKTHLSRDAEADHGRFQLELECSKFPMPHVNGLSPELSMNGHATPYEIHNTFSRP
SSKQNTPQYMTSHLDQEIVPCTPNHSRQKADRMASLSLPDYTRFSPAKIALRRHLNQDHT
VNGKATTSEIQRADHVKENGLTYPSPSISNGIKLSPQETRPSSPAALPIAGEKVLRERTS
VSNGETITSLPISIPLSTVQPNKLPVSIPLASVVLPSRVEKVRSTPSPVHQSRDSSTLEK
QIGASSHNGVSNAAGNKPLALATSGFSYSSGSVAVNGNLTNSPAHLNHSVDQAALDDSGS
LFNSVGSRSSTPQHPLLMMQSRNSGQSSPAHQHSASPRLNGTSQSLVGGLHYADAQKMFA
EGTKGDLQSDAAFSDPENEAKRRIIFTISPNTGHVKQSPSTKHSPLPASARLDCGPAHGQ
DGKKRGRRKRSSTGNLSGGSGVSPKRKSLPAVSGLFTQPSGSPLNINSMVNNINQPLEIT
AISSPENSLKNSPVPYQDNDQPPVLKKEKPLTQSNGVHYSPLTSDDEQGSEDEHNSTRIE
RKIATISLESKSPQKTVENGGSLSGRKQAQPNENMNSSKWKSTFSPISDINLTKTTDSPL
QSVSSLSQNSLFAFRPSSEDSLAMDAKMAHARKGMAMPSSGADGLSPSTNPTNGFAYNGG
LSTDIGLHSFIDGASLPHKASDGTAAACSLGFQSQRSKDVGISETNPFLNKRQLEGLGGA
KGEDLSRAGVKSKDMSEMSIRAGGSSEKNSLQHNGKVGKGRDRDVEFKNGHNLFISAAVS
SGGLLNGKSLSTAVSSAGNPASSVQTHHPFLNTLTTGSQFPLGPMALQANLNSVTNSSVL
QSLFNSMPAAASLVHVSSAATRLTNSHTMGNFSPGVTGGTVGGIFNHAVPSASSPHQFGA
SFSSSAVSSSTVLSLNPLQAVASTSSSSFPPPSSNLVTSSENRAAQHLNRAPVQSVFHPP
PPPPNVSLPPPPPLLASNPDLLHSPSIPPGDAFLPSSSAASVHSNTALSIKLASLQHKAS
RPSFTVHHPPLPRSALAQSVPPMAQPTAAGAPAMWVTLGMQPPSASHLSGVKPR
NT seq
5205 nt
NT seq
+upstream
nt +downstream
nt
atgggcgagcggctggagctgcgcctcaagtcgccggtgggagccgagcccgccgtgtac
ccgtggccgctgcccgtctacgacaaacaccatgatgctgctcatgaaatcattgagaca
attcggtgggtctgtgaagaaatcccagatctcaagcttgctatggaaaactacgttcta
attgactatgacacaaaaagctttgaaagcatgcagcggctgtgtgacaagtacaaccgc
gccatcgacagcatccatcagctgtggaagggaaccacccaaccgatgaagctgaacact
cgtccctccaacgggctcctccggcacatcctgcagcaggtttacaaccactcggtgacc
gaccccgagaaactcaacaactacgagcccttctcccctgaggtgtatggagaaacctcc
ttcgacctggtggcccagatgatagatgagattaaaatgacagaggacgacctctttgtc
gacttgggcagcggtgtgggtcaggtggtgcttcaagtggccgcagccacgaactgcaaa
catcactatggtgtggagaaagctgacattccagccaaatacgctgagacgatggacaga
gagttcagaaagtggatgaaatggtatgggaaaaaacatgcagaatacacactggaaaga
ggtgacttcctctcagaagaatggagagagagaattgcaaacacaagtgttatttttgtg
aataattttgcctttggtcctgaggtggatcaccaactgaaggagcgatttgccaacatg
aaggaaggtgggagaattgtgtcctcaaaaccttttgcacctctgaatttcagaattaac
agtcgaaacttgagtgatattggcactataatgagagtcgtggagctgtcaccactgaaa
ggctctgtgtcgtggactgggaagccagtctcttactacctgcatactattgaccgaacc
atacttgaaaactatttttctagtctcaaaaatccaaaactcagggaggaacaagaggca
gctagacgtcgtcagcagcgagaaaacaagagcaacacgactactccaacgaaggttcaa
gaaaacaaggattctggtgctgaagaagaaaaagctggggcaaatgctgttaaaaagcca
tctccctctaaagcaaggaagaaaaaactgagcaaaaaaggaaggaaaatggcaggcagg
aagcgagggcgtcccaagaaaatgaacactgcaaatacggagcgcaagaccaagaagaac
caaactgcactagaacttctgcatgctcaaactgtgtcacagacatcttcatcctctcct
caggatgcatacaagtcacctcatagtccatattaccaactacctcctaaagtgcaacgg
cattcatccaaccagctgctggtgacacccaccccacctgcactacagaagctgctagac
tcttttaagatccagtacatgcagttcatggcgtacatgaaaactcctcaatataaagca
agtctgcaacagttgctggagcaggagaaggagaagaatgcacagctactggggacggcg
cagcagttgttcacccactgccaggcacagaaagaggaaatcaaacgtctttttcagcag
aaactcgatgagttgggagtgaaggctctgacatacaacgacctgattcaggctcagaag
gaaatctctgctcacaatcagcagctgaaagaacagaccaaacagctggagaaggataac
agcgaactcaggaaccagagcctgcagctgctgaaggcacgctgcgaagagctgaagcta
gattggtccacgctgtcactggagaacttgctgaaggagaagcaggctctgaagaatcag
atttctgagaaacaaaagcactgtttggaactgcagatcagcattgtggaacttgagaaa
agccaaaggcagcaggagctcatgcagctgaaatcgtacacgccgtcggatgagtcactg
tcagtgcagctacggaataaaacccacctgagccgcgatgctgaggctgatcatggcagg
ttccagctggagctcgagtgctccaagtttcctatgccccacgtcaatggcttgagcccc
gaactgtccatgaatggccacgctactccctatgagattcacaacactttcagcaggccg
tcctccaagcagaacacccctcagtacatgacctctcatctggaccaagaaatagttcca
tgtaccccaaaccacagcaggcagaaggcggacaggatggcgagcctgtccttacctgat
tataccaggttttcccctgcgaaaatagcactaaggagacacttgaatcaagaccacaca
gtcaatggaaaagcaacaacgagtgagatacagagagctgaccacgtcaaagagaacggc
cttacatatccaagccccagtatttccaatggcatcaagctgagtcctcaggaaactcgg
ccctcttccccagcggccttaccgattgcaggcgagaaggttttgagagagagaacctct
gtgagtaatggagaaactatcaccagcctacccatcagtattcctctcagcacagtgcag
cccaataagctccctgttagcatccctctggccagcgtagttctgcctagccgtgttgag
aaggtgagaagcacacctagcccagttcatcagagcagagactcatcgacacttgaaaag
cagattggtgctagttctcataatggtgtaagcaatgctgctggaaacaagccactggct
ttggctacctcaggtttttcttactcttctggctccgtggcagtcaatggaaatcttaca
aacagcccagcccatcttaaccatagtgttgatcaggcagctctggacgactctgggagt
ctgtttaactcagtagggtctcggagttccactccacaacatcctttgctaatgatgcag
tcgaggaactctgggcaaagctcccctgctcaccagcactcagcaagccccaggttaaat
ggcacctcccagagcctggtagggggactgcactatgcagatgctcagaagatgtttgcc
gaaggaacaaagggggatcttcagtctgatgcagcattttcagatcctgagaacgaggcc
aagagaagaatcatctttacaatctctcctaatacaggacatgtaaaacaatccccttcc
accaagcacagccctctgcccgcgagcgctcggctggactgcggcccagcacacgggcag
gacgggaagaagcgcggccggcggaagagatcctccactgggaacctcagcgggggctcc
ggggtctcccccaaacgcaaatccttgcccgctgtgtccggactctttacgcagccatca
ggttcaccgctcaatatcaactccatggtcaataacattaaccagcctttagaaataaca
gccatttcctctcctgaaaactccctgaagaactctcctgttccttaccaggacaacgac
cagcccccggtactgaaaaaggaaaagcccctcactcagagcaacggcgttcattactcc
cctctcacgtcagatgacgagcagggatctgaagatgagcacaacagcaccaggatcgag
aggaaaattgcaacgatatcgctggaaagcaaatctccacagaagactgttgaaaatggt
ggcagcttatctgggaggaaacaagcacaacccaacgagaacatgaacagcagcaaatgg
aaatctactttctcaccaatatctgacatcaacctgaccaaaaccacggacagtcccttg
cagtctgtgtcgtctctgagccagaattcgctgtttgccttcaggccgtcctctgaggac
agcctcgccatggatgccaagatggcacacgcaaggaaaggcatggccatgccctcgtcg
ggggcagacgggctcagccccagcacaaaccccaccaacgggttcgcctacaacggtggg
ctgtcgactgacattggtttacacagctttatcgatggtgcttctcttccacacaaggcc
tcggacgggacggccgctgcctgctctctggggttccagtcgcagcggagcaaagatgtg
gggatatcggaaacaaaccctttcttgaacaagaggcaactcgaaggcctcggcggcgcc
aagggagaagacctcagccgggcaggagtcaaaagcaaagacatgagtgaaatgagcatt
cgtgcggggggttcttcagagaaaaactctttgcagcataacggaaaggtcggcaaagga
agggaccgagatgtggagttcaaaaacggccataaccttttcatttctgctgctgtttca
tctggtggccttctgaatgggaaaagcctttctactgctgtttcttcagcaggcaaccca
gcatcgtctgtgcagacgcaccatcccttcctcaacactttgaccactggatcgcagttc
cccctcggccccatggccttgcaagccaacctcaactcggtgacaaactcctcagtattg
cagtccttatttaattccatgccagctgctgccagtctggtccacgtgtcgtcagctgca
accagactgactaattctcacactatggggaacttctctcctggggttacaggtggaaca
gttggaggtatttttaaccatgcggtgccttctgcctcctctcctcatcagtttggagcc
agtttcagcagcagtgctgtctctagcagcacagtgctaagcttaaaccccctgcaggct
gttgccagcacctcgtcctcatccttcccacccccctcctctaatttagtaacatctagc
gagaatagagccgctcagcacctcaacagagcgccagtgcaatctgttttccatcctcct
ccgccccctcctaacgtttccttgcccccacccccccctctgctcgcttctaaccccgac
ctcctgcacagcccatccatcccacccggcgacgctttcctgccatcctcttccgccgct
tctgtccactctaacaccgctttgtctatcaagctcgcttccctgcagcacaaagcctcc
cgcccctcctttaccgtccaccacccccccctgccccgctcggcgctggcacagtccgtg
cccccgatggcgcagcccacggccgccggcgcgcccgccatgtgggtcacgcttggcatg
cagcctccttccgcttcgcacctttctggggttaagccgcgataa
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integrated database retrieval system
