Geobacillus kaustophilus: GK1887
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Entry
GK1887 CDS
T00217
Symbol
iolA
Name
(GenBank) methylmalonate-semialdehyde dehydrogenase
KO
K00140
malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:
1.2.1.18
1.2.1.27
]
Organism
gka
Geobacillus kaustophilus
Pathway
gka00280
Valine, leucine and isoleucine degradation
gka00410
beta-Alanine metabolism
gka00562
Inositol phosphate metabolism
gka00640
Propanoate metabolism
gka01100
Metabolic pathways
gka01200
Carbon metabolism
Brite
KEGG Orthology (KO) [BR:
gka00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
GK1887 (iolA)
00562 Inositol phosphate metabolism
GK1887 (iolA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
GK1887 (iolA)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
GK1887 (iolA)
Enzymes [BR:
gka01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
GK1887 (iolA)
1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
GK1887 (iolA)
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Motif
Pfam:
Aldedh
Motif
Other DBs
NCBI-ProteinID:
BAD76172
UniProt:
Q5KYR4
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Position
complement(1917227..1918693)
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AA seq
488 aa
AA seq
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MDMTMTTGVQTLKNYIGGQWVESRSGKTEAVPNPATGEVLAYVPISSREELDEAVRAAKE
AFKTWRKTPVPRRARILFKYQQLLVEHWEELARLVTLENGKSYNEAYGEVQRGIECVEFA
AGAPTLMMGRQLPDIATGIESGMYRYPIGVVGGITPFNFPMMVPCWMFPLAIACGNTFVL
KPSERTPMLANRLAELFKEAGLPDGVLNIVHGAHDVVNGLLEHPDVKAISFVGSQPVGEY
VYKTAAAHGKRVQALTGAKNHSIVMPDADLNVAVREIINAAFGSAGERCMAASVVVAVGE
IADELVEKLVAAANELKIGNGLEESVFLGPVIREAHKQRTVKYIELGEKEGAILVRDGRK
DAAVQDNGYFIGPTIFDRVTTDMTIWKDEIFAPVLSIVRVETLDEAIEVANKSPFANGAC
IYTRDGGNVRKFREEIDAGMLGVNLGVPAPMAFFPFSGWKNSFYGDLHANGMDGVEFYTR
KKMMTSRW
NT seq
1467 nt
NT seq
+upstream
nt +downstream
nt
atggacatgacgatgacaacgggagtgcaaaccttaaaaaactatattggcgggcaatgg
gtcgagtctcgttccgggaagacggaagccgttccgaacccggcaacgggcgaagtgttg
gcctacgttccgatttcaagccgcgaggagttggacgaagcggtccgagctgccaaagag
gcgttcaaaacatggcgcaaaacgccggtgccgcgccgggcaagaatcttgtttaaatat
cagcagttgcttgtcgagcattgggaagagctggcccgattggtgacgttagaaaacggc
aaaagctacaacgaagcatatggggaagtgcaacgcggcattgaatgcgtcgaatttgcg
gccggtgcgccgacgctcatgatggggcggcagcttccagatattgcgaccggcattgaa
tcggggatgtaccggtatccgatcggcgtcgtggggggcatcacgccgtttaacttcccg
atgatggtcccttgctggatgttcccgctggcgattgcgtgcggaaacacgttcgtctta
aaaccgtccgagcgcacgccgatgttggcgaatcgtttggctgaactgtttaaagaggct
gggcttccggacggggtgcttaacatcgtccatggggcgcatgatgtcgtgaacgggctg
ttggagcacccggatgtgaaagccatctcgtttgtcggctcccagccggtcggcgagtat
gtgtacaaaacggcagcggctcacggcaaacgggttcaagcgttgacgggggcgaaaaac
cattccattgtcatgccggatgccgatttgaatgttgcggtccgtgaaattattaacgca
gcgttcggctcggcgggagaacggtgcatggcggcgtcggtcgttgtcgcggttggggag
attgccgatgaacttgtcgagaagctggtggcggccgcgaatgaattgaaaatcggcaat
gggctggaggagagcgtctttttaggcccggtcattcgcgaagcccataagcaacggacc
gtgaagtatattgaacttggggaaaaggaaggggccattctggtgcgcgacggacgaaag
gacgccgcggttcaggataatggatactttatcggtccgacgatttttgaccgagtcact
actgacatgaccatttggaaagacgaaattttcgcccctgttctttcgatcgtacgggtc
gagacattagatgaagccattgaggtggccaacaagtctccgtttgccaatggagcgtgc
atctatacaagagacggggggaatgtccgcaaattccgcgaggaaatcgacgctggcatg
ttaggcgtcaacttaggcgttcccgcgccgatggcgttcttcccgttctccgggtggaaa
aactcgttttatggcgatcttcatgcgaacggcatggatggcgtcgagttttatacgcgc
aaaaaaatgatgacctcccgctggtaa
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