Herminiimonas arsenicoxydans: HEAR1242
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Entry
HEAR1242 CDS
T00490
Symbol
leuA2
Name
(GenBank) 2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase)
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
har
Herminiimonas arsenicoxydans
Pathway
har00290
Valine, leucine and isoleucine biosynthesis
har00620
Pyruvate metabolism
har01100
Metabolic pathways
har01110
Biosynthesis of secondary metabolites
har01210
2-Oxocarboxylic acid metabolism
har01230
Biosynthesis of amino acids
Module
har_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
har00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
HEAR1242 (leuA2)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
HEAR1242 (leuA2)
Enzymes [BR:
har01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
HEAR1242 (leuA2)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
CAL61418
UniProt:
A4G4I1
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All DBs
Position
1260866..1262413
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AA seq
515 aa
AA seq
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MAVDSNKLIIFDTTLRDGEQSPGASMTRDEKIRIARQLERLKVDIIEAGFAAASQGDFES
IHAISGIIKDATVCSLSRANDKDIARAAEALKPAARKRIHTFLATSPLHMEKKLRMTPDQ
VFEQAKIAVRYARQFTDDVEFSPEDGSRSDMDFLCRVIEAVIKEGATTINFADTVGYAVP
ELYGNMLRTLRERIPNSDKAVWSVHCHNDLGMGVANSLAGVMIGGARQVECTINGLGERA
GNTALEEIVMAVRTRKDYFNLEIGVDATQIVPTSKLVSQITGFAVQPNKSVVGANAFAHA
SGIHQDGVLKARDTYEIMRAEDVGWSANKIVLGKLSGRNAFKQRLEELGITMESAADTDA
AFIRFKELADRKSEIFDEDIMALVSDEQHSHEHEYYNFVSLTQQSSSASKPVASVVFSMG
GKEEICKGEGNGPVDAIVNAIESKVASGAELLLFSVNAITTGTESQGEVTMRLSKAGRIV
NGVGADLDIVVASAKAYISALNKLHSKIEKLNPQL
NT seq
1548 nt
NT seq
+upstream
nt +downstream
nt
atggcagtcgattcaaataaactgattatttttgataccaccttgcgcgatggcgaacag
tcgccgggtgcatcgatgaccagggatgaaaaaatccgcatcgccagacagctggagcgt
ctgaaggtcgatattatcgaagccggttttgctgccgcctcacaaggtgatttcgaatca
atccatgcaatctccggcatcatcaaggatgcaacggtttgttctttgtcgcgcgccaac
gataaggatatcgcgcgtgcagcagaggcgctgaaaccggcggcaagaaagcggattcac
acttttcttgcgacttcaccgttgcatatggaaaaaaagctgcgcatgacgccggatcag
gtattcgagcaagccaagatcgcagtgcgttatgcacggcaatttaccgatgatgtcgag
ttcagtccggaagacggcagccgttcggatatggattttctgtgtcgcgtgattgaagct
gtgatcaaggaaggtgcaacgaccatcaactttgccgacacggttggttacgccgtgcct
gagttgtacggcaacatgctgcggaccttgcgtgagcgtattccgaattccgacaaggcg
gtctggtcagttcattgccacaacgatcttggcatgggggttgccaattcgctcgccggc
gtcatgataggcggcgcgcgccaggttgagtgcacgatcaacggtttgggtgagcgcgca
ggcaataccgcgctggaagaaatcgtgatggccgtgcgtacgcgcaaggactacttcaat
ctggaaattggcgtcgatgctacacagatcgtcccgacttccaaactggtttcgcagatt
accggttttgccgtgcagccgaacaaatcggtggtgggtgcaaacgcatttgcacatgca
tcggggatacaccaggacggcgtgctgaaggcgcgcgatacctatgaaatcatgcgtgcc
gaagacgtgggctggtctgccaataaaatcgtcctgggcaagctgtcaggtcgcaatgcc
ttcaagcaacgtcttgaggaattggggatcaccatggaatcggctgcggatacggatgcc
gcattcatacgcttcaaggaactggccgatcgcaagtctgagatctttgatgaagacatc
atggccctggtatccgacgagcagcattcgcatgaacacgaatactacaatttcgtttcc
ctgacgcagcaatcgtccagtgcaagcaaacctgttgccagtgtcgtattttcgatgggc
ggcaaggaagaaatctgcaaaggtgagggcaatggtccggttgatgcaatcgtcaatgcc
attgaatcgaaagtggcaagcggggcggaattgctgctgttttcagtcaatgcgattact
accggtaccgaatcccagggcgaagtcacgatgcgtttgtcgaaggctggtcgtatcgtc
aatggcgtcggtgcggatcttgatatcgtcgtggcctcggcaaaagcctacatctctgcg
ctgaataaattgcattcgaagatagaaaagctgaatcctcagctttaa
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