Heterocephalus glaber (naked mole-rat): 101702965 Help Entry 101702965         CDS       T02812                                  Symbol Gnai1 Name (RefSeq) G protein subunit alpha i1   KO K04630   guanine nucleotide-binding protein G(i) subunit alpha Organism hgl  Heterocephalus glaber (naked mole-rat) Pathway hgl04015   Rap1 signaling pathway hgl04022   cGMP-PKG signaling pathway hgl04024   cAMP signaling pathway hgl04062   Chemokine signaling pathway hgl04071   Sphingolipid signaling pathway hgl04261   Adrenergic signaling in cardiomyocytes hgl04360   Axon guidance hgl04371   Apelin signaling pathway hgl04540   Gap junction hgl04611   Platelet activation hgl04670   Leukocyte transendothelial migration hgl04713   Circadian entrainment hgl04723   Retrograde endocannabinoid signaling hgl04724   Glutamatergic synapse hgl04725   Cholinergic synapse hgl04726   Serotonergic synapse hgl04727   GABAergic synapse hgl04728   Dopaminergic synapse hgl04730   Long-term depression hgl04914   Progesterone-mediated oocyte maturation hgl04915   Estrogen signaling pathway hgl04916   Melanogenesis hgl04921   Oxytocin signaling pathway hgl04923   Regulation of lipolysis in adipocytes hgl04924   Renin secretion hgl04926   Relaxin signaling pathway hgl04928   Parathyroid hormone synthesis, secretion and action hgl04934   Cushing syndrome hgl04935   Growth hormone synthesis, secretion and action hgl04971   Gastric acid secretion hgl05012   Parkinson disease hgl05030   Cocaine addiction hgl05032   Morphine addiction hgl05034   Alcoholism hgl05133   Pertussis hgl05142   Chagas disease hgl05145   Toxoplasmosis hgl05163   Human cytomegalovirus infection hgl05170   Human immunodeficiency virus 1 infection hgl05200   Pathways in cancer hgl05207   Chemical carcinogenesis - receptor activation Brite KEGG Orthology (KO) [BR:hgl00001]  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     101702965 (Gnai1)    04371 Apelin signaling pathway     101702965 (Gnai1)    04071 Sphingolipid signaling pathway     101702965 (Gnai1)    04024 cAMP signaling pathway     101702965 (Gnai1)    04022 cGMP-PKG signaling pathway     101702965 (Gnai1)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04540 Gap junction     101702965 (Gnai1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     101702965 (Gnai1)    04670 Leukocyte transendothelial migration     101702965 (Gnai1)    04062 Chemokine signaling pathway     101702965 (Gnai1)   09152 Endocrine system    04923 Regulation of lipolysis in adipocytes     101702965 (Gnai1)    04915 Estrogen signaling pathway     101702965 (Gnai1)    04914 Progesterone-mediated oocyte maturation     101702965 (Gnai1)    04921 Oxytocin signaling pathway     101702965 (Gnai1)    04926 Relaxin signaling pathway     101702965 (Gnai1)    04935 Growth hormone synthesis, secretion and action     101702965 (Gnai1)    04928 Parathyroid hormone synthesis, secretion and action     101702965 (Gnai1)    04916 Melanogenesis     101702965 (Gnai1)    04924 Renin secretion     101702965 (Gnai1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     101702965 (Gnai1)   09154 Digestive system    04971 Gastric acid secretion     101702965 (Gnai1)   09156 Nervous system    04724 Glutamatergic synapse     101702965 (Gnai1)    04727 GABAergic synapse     101702965 (Gnai1)    04725 Cholinergic synapse     101702965 (Gnai1)    04728 Dopaminergic synapse     101702965 (Gnai1)    04726 Serotonergic synapse     101702965 (Gnai1)    04730 Long-term depression     101702965 (Gnai1)    04723 Retrograde endocannabinoid signaling     101702965 (Gnai1)   09158 Development and regeneration    04360 Axon guidance     101702965 (Gnai1)   09159 Environmental adaptation    04713 Circadian entrainment     101702965 (Gnai1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101702965 (Gnai1)    05207 Chemical carcinogenesis - receptor activation     101702965 (Gnai1)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     101702965 (Gnai1)    05163 Human cytomegalovirus infection     101702965 (Gnai1)   09171 Infectious disease: bacterial    05133 Pertussis     101702965 (Gnai1)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     101702965 (Gnai1)    05142 Chagas disease     101702965 (Gnai1)   09164 Neurodegenerative disease    05012 Parkinson disease     101702965 (Gnai1)   09165 Substance dependence    05030 Cocaine addiction     101702965 (Gnai1)    05032 Morphine addiction     101702965 (Gnai1)    05034 Alcoholism     101702965 (Gnai1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     101702965 (Gnai1)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hgl04147]     101702965 (Gnai1)    04031 GTP-binding proteins [BR:hgl04031]     101702965 (Gnai1) Exosome [BR:hgl04147]  Exosomal proteins   Proteins found in most exosomes    101702965 (Gnai1) GTP-binding proteins [BR:hgl04031]  Heterotrimeric G-proteins   Alpha Subunits    Alpha type 1 (Gi/o) [OT]     101702965 (Gnai1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  G-alpha Arf Gtr1_RagA TniB FtsK_SpoIIIE AAA_29 Motif Other DBs NCBI-GeneID:  101702965 NCBI-ProteinID:  XP_004839806 LinkDB All DBs Position Un AA seq 354 aa AA seqDB search MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAG YSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMT AELAGVIQRLWKDSGVQTCFSRSREYQLNDSAAYYLNDLDRIAQANYIPTQQDVLRTRVK TTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAA AYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF NT seq 1065 nt NT seq  +upstreamnt  +downstreamnt atgggctgcacgctgagcgccgaggataaggcggccgtggagcgcagcaagatgatcgac cgcaacctgcgcgaggacggcgagaaggcggcgcgcgaggtcaagctgctgctgctcggt gctggtgaatctgggaaaagtacaattgtaaagcagatgaaaattatccatgaggcgggg tattcggaagaggaatgcaagcagtacaaagcagtggtctacagcaacaccatccagtcc atcattgctattatcagggccatgggaagattgaagatagacttcggtgactctgctcgg gcggatgatgctcgccagctatttgtgcttgcgggagctgccgaagaaggctttatgacc gcagagctcgctggagttatacagagattgtggaaagatagtggagtgcagacctgcttc agcagatcccgggagtaccagctgaatgactccgcagcatactatttgaacgacctggac agaatagcacaagccaactacatcccaactcagcaagacgttctcagaaccagggtgaaa acaactggcattgttgagacccattttactttcaaagaccttcattttaagatgtttgac gtgggcgggcagaggtccgagcggaagaagtggatccactgcttcgagggtgtgactgcc atcatcttctgtgtggccctgagtgactacgacctggttctggctgaagatgaagaaatg aatcgaatgcatgaaagcatgaaactgttcgacagcatatgtaacaacaaatggtttacg gatacgtctattatactttttctaaacaagaaggatctcttcgaagaaaaaatcaaaaag agccccctcactatctgctatccagaatatgcaggatcaaacacatatgaagaggcagct gcatatattcagtgtcagtttgaggacctgaataagagaaaagacacaaaggaaatatac acccacttcacatgtgccaccgatactaagaatgtgcagttcgtgttcgatgccgtgacc gacgtcatcataaaaaataacctaaaagactgtggtctcttctaa

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