Heterocephalus glaber (naked mole-rat): 101704397
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Entry
101704397 CDS
T02812
Symbol
Tgfbr2
Name
(RefSeq) transforming growth factor beta receptor 2
KO
K04388
TGF-beta receptor type-2 [EC:
2.7.11.30
]
Organism
hgl
Heterocephalus glaber (naked mole-rat)
Pathway
hgl04010
MAPK signaling pathway
hgl04060
Cytokine-cytokine receptor interaction
hgl04068
FoxO signaling pathway
hgl04144
Endocytosis
hgl04218
Cellular senescence
hgl04350
TGF-beta signaling pathway
hgl04380
Osteoclast differentiation
hgl04390
Hippo signaling pathway
hgl04520
Adherens junction
hgl04659
Th17 cell differentiation
hgl04926
Relaxin signaling pathway
hgl04933
AGE-RAGE signaling pathway in diabetic complications
hgl05142
Chagas disease
hgl05161
Hepatitis B
hgl05166
Human T-cell leukemia virus 1 infection
hgl05200
Pathways in cancer
hgl05202
Transcriptional misregulation in cancer
hgl05210
Colorectal cancer
hgl05212
Pancreatic cancer
hgl05220
Chronic myeloid leukemia
hgl05225
Hepatocellular carcinoma
hgl05226
Gastric cancer
hgl05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
hgl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101704397 (Tgfbr2)
04350 TGF-beta signaling pathway
101704397 (Tgfbr2)
04390 Hippo signaling pathway
101704397 (Tgfbr2)
04068 FoxO signaling pathway
101704397 (Tgfbr2)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
101704397 (Tgfbr2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101704397 (Tgfbr2)
09143 Cell growth and death
04218 Cellular senescence
101704397 (Tgfbr2)
09144 Cellular community - eukaryotes
04520 Adherens junction
101704397 (Tgfbr2)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
101704397 (Tgfbr2)
09152 Endocrine system
04926 Relaxin signaling pathway
101704397 (Tgfbr2)
09158 Development and regeneration
04380 Osteoclast differentiation
101704397 (Tgfbr2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101704397 (Tgfbr2)
05202 Transcriptional misregulation in cancer
101704397 (Tgfbr2)
09162 Cancer: specific types
05210 Colorectal cancer
101704397 (Tgfbr2)
05212 Pancreatic cancer
101704397 (Tgfbr2)
05225 Hepatocellular carcinoma
101704397 (Tgfbr2)
05226 Gastric cancer
101704397 (Tgfbr2)
05220 Chronic myeloid leukemia
101704397 (Tgfbr2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
101704397 (Tgfbr2)
05161 Hepatitis B
101704397 (Tgfbr2)
09174 Infectious disease: parasitic
05142 Chagas disease
101704397 (Tgfbr2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101704397 (Tgfbr2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
101704397 (Tgfbr2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hgl01001
]
101704397 (Tgfbr2)
Enzymes [BR:
hgl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
101704397 (Tgfbr2)
Protein kinases [BR:
hgl01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR2 family [OT]
101704397 (Tgfbr2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ecTbetaR2
PK_Tyr_Ser-Thr
Pkinase
ABC1
Haspin_kinase
APH
Motif
Other DBs
NCBI-GeneID:
101704397
NCBI-ProteinID:
XP_004857873
UniProt:
A0AAX6PSS4
LinkDB
All DBs
Position
Un
AA seq
611 aa
AA seq
DB search
MGRRLLRGLWPLHIVLWTRIASTIPPQVQKSGSERQIIRRDLAAEQVPMTDMEVEARKDE
TIFLSCNRTIHSLNLFNNDMMATETNGAVKFSQLCKFCDVRSSTCDNQKSCMSNCSITSI
CEKSHEVCVAVWRKNDENITLETVCHDPELPYHGFILEDATSLKCIMKEKKVLGETFFMC
SCSADECNDHIIFSEEYAASSPDLWLVIFQVTGVSLLPPLGIAIAVIIIFYCYRVHRQQK
LSPSWESSKPRKLMEFSEHCAIILEDDRSDISSTCANNINHNTELLPIELDTLVGKGRFA
EVYKAKLKQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLKHENILQFLTAEERKTE
LGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAHLHSDHTPCGRPKMPIV
HRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNL
ENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVREHPCVESMKDNVLRDRG
RPEIPSFWLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFSELEHLDRLSRRSCSEEK
IPEDGSLNTTK
NT seq
1836 nt
NT seq
+upstream
nt +downstream
nt
atgggtcggcggctgctccggggcctgtggccgctgcacatcgtcctgtggacgcgcatc
gccagcacgatcccaccgcaagttcagaagtcggggtcagagcgacaaatcatcagaagg
gatttagctgcagagcaagtgcctatgactgatatggaagtggaggcccggaaagatgaa
accatcttcttaagctgtaataggaccattcattcactgaacctgtttaataatgacatg
atggccaccgaaacgaatggtgcagtcaagttttcacaactctgcaaattttgtgatgtg
agatcttccacctgtgacaaccagaaatcctgcatgagcaactgcagcatcacatccatc
tgtgagaagtcacatgaagtctgtgtggccgtatggcggaagaatgacgagaacataaca
ctagagacggtttgccatgaccctgagctcccctaccatggatttattctggaagatgct
acttcgttgaagtgcattatgaaggaaaaaaaagtgcttggcgagactttctttatgtgc
tcctgtagtgctgatgaatgcaacgaccacatcatcttctcagaagaatatgctgcaagc
agtcctgacttgtggttagtcatattccaagtgacaggagtcagtcttctgccgcctctg
ggaatcgccatagctgtcatcattattttctactgctaccgtgttcaccggcagcagaag
ctgagcccatcctgggagagtagcaagccacgaaagctcatggagttcagtgagcactgt
gccatcattctggaagatgaccgctctgacatcagctccacatgtgccaataacatcaac
cacaacacggagctcctgcccatcgagctggacacactggtgggcaaaggccgcttcgct
gaggtttacaaggccaagttgaagcagaacacttcagagcagttcgagactgtagcagtc
aagatcttcccctatgaggagtatgcctcttggaagacagagaaagacatcttctcagac
atcaacctgaagcatgagaatatcctccagtttctcacagctgaggaacggaagacagag
ttggggaaacagtactggttgatcactgccttccatgccaagggcaaccttcaggagtac
ctcacccggcatgtcatcagctgggaggacctgcgcaagttgggcagttcccttgcccgg
ggcatcgcccacctccatagtgaccacacaccatgtgggagacctaaaatgcccatcgtg
cacagagatctcaagagctccaacatcctcgtgaagaatgatctgacctgctgcctctgc
gactttgggctttccctgcgtctggaccctactctgtctgtagatgacctggccaacagt
gggcaggtgggaactgcaagatacatggccccagaagtcctggaatccaggatgaacttg
gagaatgttgagtccttcaagcagaccgatgtttactctatggctttggtgctctgggaa
atgacatctcgctgtaatgctgtgggagaggtaaaagattatgagcctccatttggttcc
aaggtgcgggagcacccttgtgttgagagcatgaaggacaatgtgttaagagacagagga
cgaccagaaattcccagcttctggctcaaccaccagggcatccagatggtgtgtgagaca
ctgacagagtgctgggaccacgacccagaggcgcgtctcacggcccaatgtgtggcggaa
cgctttagcgagctggagcacctggacagactctcccggaggagctgctcggaggagaag
attcccgaagatggctcgctgaacactaccaaatag
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