KEGG ORTHOLOGY: K03957

ORTHOLOGY: K03957

Entry

K03957                      KO

Symbol

NDUFB1

Name

NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1

Pathway

map00190

Oxidative phosphorylation

map01100

Metabolic pathways

map04714

Thermogenesis

map04723

Retrograde endocannabinoid signaling

map04932

Non-alcoholic fatty liver disease

map05010

Alzheimer disease

map05012

Parkinson disease

map05014

Amyotrophic lateral sclerosis

map05016

Huntington disease

map05020

Prion disease

map05022

Pathways of neurodegeneration - multiple diseases

map05208

Chemical carcinogenesis - reactive oxygen species

map05415

Diabetic cardiomyopathy

Module

M00147

NADH dehydrogenase (ubiquinone) 1 beta subcomplex

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    K03957  NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    K03957  NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
  09159 Environmental adaptation
   04714 Thermogenesis
    K03957  NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    K03957  NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K03957  NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
   05012 Parkinson disease
    K03957  NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
   05014 Amyotrophic lateral sclerosis
    K03957  NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
   05016 Huntington disease
    K03957  NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
   05020 Prion disease
    K03957  NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
   05022 Pathways of neurodegeneration - multiple diseases
    K03957  NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    K03957  NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    K03957  NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1

Other DBs

TC:

3.D.1.6

Genes

HSA:	4707(NDUFB1)

PTR:	453115(NDUFB1)

PPS:	100977796(NDUFB1) 117979653

GGO:	101132014(NDUFB1)

PON:	100173590(NDUFB1)

NLE:	100603049(NDUFB1) 115834798

HMH:	116476238 116484857(NDUFB1)

MCC:	697745(NDUFB1)

MCF:	102114911(NDUFB1) 123571832

MTHB:

126948765 126959705

MNI:	105467540(NDUFB1)

CSAB:

103229567(NDUFB1)

CATY:

105596585(NDUFB1)

PANU:

101019309(NDUFB1)

TGE:	112628956(NDUFB1)

MLEU:

105547955(NDUFB1)

RRO:	104679039(NDUFB1)

RBB:	108519146(NDUFB1)

TFN:	117063948 117071524(NDUFB1)

PTEH:

111538232(NDUFB1) 111555537

CANG:

105517293(NDUFB1)

CJC:

108593137

CIMI:

108301529 119467181

CSYR:

110594486(NDUFB1)

LCAT:

123639645 123645245(NDUFB1)

PCOQ:

105815301(NDUFB1)

OGA:	105886827(NDUFB1)

MMU:	102631912(Ndufb1)

MCAL:

110306743(Ndufb1)

MPAH:

110324555(Ndufb1)

MCOC:

116079733(Ndufb1)

ANU:	117697135(Ndufb1)

MUN:	110556444(Ndufb1) 132646281 132646755 132652734

CGE:

100754039

MAUA:

101839807(Ndufb1)

PLEU:

114704425 114706041(Ndufb1)

MORG:

121434340(Ndufb1) 121443386

MFOT:

126507225

AAMP:

119818574(Ndufb1)

HGL:	101726682(Ndufb1)

CPOC:

101789289(Ndufb1)

DORD:

105985899(Ndufb1)

DSP:	122118714(Ndufb1)

PLOP:

125340774 125344035 125363145(Ndufb1) 125367165

NCAR:

124977589

MMMA:

107144262 107149970(Ndufb1)

OCU:	103348994 127484881

OPI:	101528550(NDUFB1) 105941651

TUP:	102472441(NDUFB1)

GVR:	103594734(NDUFB1)

CFA:

111096466

CLUD:

112646040 118351720 118355324 118355555(NDUFB1)

VVP:	112909583(NDUFB1) 112921738

VLG:	121486758 121493192(NDUFB1) 121494694 121501157

AML:	100478953(NDUFB1) 117802616

UMR:	103673805(NDUFB1)

UAH:	113267167(NDUFB1)

UAR:	123778638 123798882(NDUFB1)

ELK:

111148723

LLV:	125085582 125091537

MPUF:

101694062(NDUFB1)

MNP:

132009946

MLK:

131825818

NVS:	122894479(NDUFB1)

ORO:	101371446(NDUFB1) 105757340

EJU:	114206853 114208394(NDUFB1)

ZCA:	113908954(NDUFB1) 113911795 113912479 113916205 113925679

MLX:	118002675(NDUFB1) 118009264 118025455

NSU:	110571749(NDUFB1) 123323387 123323596 123324034 123324583 123324840 123325710

FCA:	101086911(NDUFB1) 123380058

PYU:	121017835 121032405(NDUFB1) 121033545

PCOO:

112856171(NDUFB1)

PBG:	122469459(NDUFB1) 122472084 122491047

PVIV:

125167608(NDUFB1) 125175126

LRUF:

124512565 124519347 124526583

PTG:	102970864(NDUFB1)

PPAD:

109274474(NDUFB1)

PUC:	125909241 125917067 125917871

AJU:

106987907

HHV:	120232078(NDUFB1)

BTA:	327690(NDUFB1)

BOM:	102278125(NDUFB1)

BIU:	109575488(NDUFB1)

BBIS:

104985816(NDUFB1)

CHX:	102189802(NDUFB1)

OAS:	101113437(NDUFB1) 114115567

BTAX:

128066874(NDUFB1)

ODA:	120874989(NDUFB1) 120875577

CCAD:

122424053 122434670 122455060(NDUFB1)

SSC:	100739619(NDUFB1)

CFR:	102511004(NDUFB1) 116664480 116666587

CBAI:

105079871(NDUFB1)

CDK:	105096144(NDUFB1) 105096996

VPC:	116281018(NDUFB1)

BACU:

103016811

BMUS:

118886657 118889623 118890227(NDUFB1)

LVE:

103087083

OOR:	101281008 101288261(NDUFB1)

DLE:	111164113 111175981(NDUFB1)

PSIU:

116743541 116746195 116748898(NDUFB1) 116749859 116763498

NASI:

112393871(NDUFB1) 112406732

ECB:	100630425(NDUFB1)

EPZ:	103557592(NDUFB1)

EAI:	106825375(NDUFB1)

MYB:	102256003(NDUFB1)

MYD:	102751928(NDUFB1)

MMYO:

118659585(NDUFB1)

MLF:	102437342(NDUFB1)

PKL:	118704211(NDUFB1) 118706341

EFUS:

103292282(NDUFB1)

MNA:	107531597(NDUFB1)

DRO:	112311794(NDUFB1)

SHON:

118976705(NDUFB1)

AJM:	119037973(NDUFB1)

PDIC:

114493073(NDUFB1)

PHAS:

123808962(NDUFB1) 123814093

MMF:	118635562 118639258(NDUFB1)

PPAM:

129065821(NDUFB1)

HAI:	109381611 109382649(NDUFB1)

RFQ:	117024244(NDUFB1) 117035392

PALE:

102898813(NDUFB1)

PGIG:

120619622(NDUFB1)

PVP:	105300789(NDUFB1)

RAY:	107511238(NDUFB1)

MJV:	108395154(NDUFB1)

SARA:

101548133(NDUFB1)

SETR:

126003626(NDUFB1) 126011378

LAV:	100660762(NDUFB1)

TMU:

101361940

ETF:	115868737(NDUFB1) 115869395 115873199

DNM:	101412040(NDUFB1)

MDO:	100016103(NDUFB1)

GAS:	123235911(NDUFB1)

SHR:	100922855(NDUFB1)

AFZ:

127549377

PCW:	110204385(NDUFB1)

OAA:	103167180(NDUFB1)

GGA:	423415(NDUFB1)

PCOC:

116228903(NDUFB1)

MGP:	100551209(NDUFB1)

CJO:	107315196(NDUFB1)

TPAI:

128085992(NDUFB1)

LMUT:

125694929(NDUFB1)

NMEL:

110402068(NDUFB1)

APLA:

101800507(NDUFB1)

ACYG:

106036568(NDUFB1)

CATA:

118244458(NDUFB1)

AFUL:

116489811(NDUFB1)

TGU:	100226767(NDUFB1)

LSR:	110471378(NDUFB1)

SCAN:

103826469(NDUFB1)

PMOA:

120503740(NDUFB1)

OTC:	121331638(NDUFB1)

PRUF:

121355975(NDUFB1)

GFR:	102038880(NDUFB1)

FAB:	101822125(NDUFB1)

PHI:	102107289(NDUFB1)

PMAJ:

107206067(NDUFB1)

CCAE:

111929878(NDUFB1)

CCW:	104686090(NDUFB1)

CBRC:

103612120(NDUFB1)

ETL:	114058211(NDUFB1)

ZAB:	102064733(NDUFB1)

ACHL:

103808165(NDUFB1)

SVG:	106849343(NDUFB1)

MMEA:

130576175(NDUFB1)

HRT:	120754023(NDUFB1)

FPG:	101914237(NDUFB1)

FCH:	102057405(NDUFB1)

CLV:	102094912(NDUFB1)

EGZ:	104135343(NDUFB1)

NNI:	104022213(NDUFB1)

PCRI:

104023716(NDUFB1)

PLET:

104615857(NDUFB1)

EHS:	104505087(NDUFB1)

PCAO:

104039311(NDUFB1)

ACUN:

113480889(NDUFB1)

TALA:

104355429(NDUFB1)

PADL:

103913006(NDUFB1)

AFOR:

103900165(NDUFB1)

ACHC:

115333722(NDUFB1)

HALD:

104312754(NDUFB1)

HLE:	104841868(NDUFB1)

AGEN:

126050483

GCL:

127016562

CCRI:

104154444(NDUFB1)

CSTI:

104564197(NDUFB1)

CMAC:

104482906(NDUFB1)

MUI:	104540406(NDUFB1)

BREG:

104639463(NDUFB1)

FGA:	104069098(NDUFB1)

GSTE:

104250207(NDUFB1)

LDI:	104339688(NDUFB1)

OHA:	104331490(NDUFB1)

NNT:	104399006(NDUFB1)

SHAB:

115606244(NDUFB1)

DPUB:

104304105(NDUFB1)

PGUU:

104460303(NDUFB1)

ACAR:

104519858(NDUFB1)

CPEA:

104394161(NDUFB1)

AVIT:

104267001(NDUFB1)

CVF:	104295573(NDUFB1)

RTD:	128908380(NDUFB1)

CUCA:

104059874(NDUFB1)

TEO:	104380012(NDUFB1)

BRHI:

104492165(NDUFB1)

AAM:	106482932(NDUFB1)

AROW:

112972611(NDUFB1)

NPD:	112953583(NDUFB1)

TGT:	104568822(NDUFB1)

DNE:	112990185(NDUFB1)

SCAM:

104153775(NDUFB1)

AMJ:	102562014(NDUFB1)

CPOO:

109321697(NDUFB1)

GGN:	109298516(NDUFB1)

PSS:	102450285(NDUFB1)

CMY:	102948331(NDUFB1)

CCAY:

125638083(NDUFB1)

DCC:	119857079(NDUFB1)

CPIC:

101945058(NDUFB1)

TST:	117876186(NDUFB1)

CABI:

116823061(NDUFB1)

MRV:	120404250(NDUFB1)

ACS:	100567760(ndufb1)

ASAO:

132763193(NDUFB1)

PVT:	110083631(NDUFB1)

SUND:

121914991(NDUFB1)

PBI:	103053581(NDUFB1)

PMUR:

114923410(NDUFB1)

CTIG:

120309581(NDUFB1)

PGUT:

117665923(NDUFB1)

APRI:

131190995(NDUFB1)

PTEX:

113444467(NDUFB1)

NSS:	113419674(NDUFB1)

VKO:	123026907(NDUFB1)

PMUA:

114590870(NDUFB1)

PRAF:

128407782(NDUFB1)

ZVI:	118080938 118081083(NDUFB1)

HCG:	128326357(NDUFB1)

GJA:	107123878(NDUFB1)

STOW:

125426652(NDUFB1)

XLA:	108698721(ndufb1.L) 108699822(ndufb1.S)

XTR:	100485816(ndufb1)

RTEM:

120921032(NDUFB1)

BBUF:

120982137(NDUFB1)

BGAR:

122921551(NDUFB1)

MUO:	115477251(NDUFB1)

GSH:	117347797 117364052(NDUFB1)

PPRM:

MAMB:

MASI:

IPU:

PHYP:

113532225(ndufb1)

SMEO:

124377247

TFD:

113655606

EEE:	113571702(ndufb1)

TRU:	115252981(ndufb1)

TFS:

130516183

TNG:	GSTEN00023016G001

LCO:	109139480(ndufb1)

NCC:	104950068(ndufb1)

TBEN:

PGEO:

GACU:

EMAC:

ELY:

EFO:

SLUC:

ECRA:

ESP:	116706864(ndufb1)

PFLV:

114572972(ndufb1)

GAT:

PPUG:

AFB:

CLUM:

PSWI:

MSAM:

SCHU:

CUD:

ALAT:

OAU:

OML:

CSAI:

XCO:	114158241(ndufb1)

XHE:	116734274(ndufb1)

GAF:

122825054

PPRL:

129375347

CVG:	107080818(ndufb1)

CTUL:

119771557

GMU:

124882141

NWH:

119418308

CSEM:

103381233(ndufb1)

POV:	109636097(ndufb1)

SSEN:

HHIP:

HSP:

SMAU:

LCF:

SDU:	111237571(ndufb1)

SLAL:

111661396(ndufb1)

XGL:

SSCV:

SBIA:

PEE:

PTAO:

MALB:

109962344(ndufb1)

BSPL:

SJO:

STRU:

OTW:

OMY:	100305186(ndufb1)

OGO:

123990908

ONE:	115107912(ndufb1)

OKI:

109900885

OKE:

118398504

SNH:	120019128 120024165

CCLU:

121552395

ELS:	105017559(ndufb1)

SFM:	108924118(ndufb1)

AANG:

118230524

LOC:	102687837(ndufb1)

PSPA:

121324561 121330183

ARUT:

117422685 117425333

PSEX:

120518433

LCM:	102349223(NDUFB1)

CMK:

103185390

RTP:

109934967

PMRN:

116953954(NDUFB1)

LRJ:	133356369(NDUFB1)

SKO:	100376803(NDUFB1)

DME:	Dmel_CG18624(ND-MNLL)

DER:

6551508

DSE:

116802210

DSI:	Dsimw501_GD26913(Dsim_GD26913)

DYA:	Dyak_GE17501

DAN:

116654453

DSR:	110184534 110184581

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI11216

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:	119670503 119671411

MDE:	105261425 131806497

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ015857

CPII:

BCOO:

AME:

ACER:

ADR:

AFLR:

BVK:

BVAN:

BPYO:

SOC:

AEC:

ACEP:

PBAR:

VEM:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

VPS:

VVE:

NVI:	100302107(Ndufb1)

CSOL:

TPRE:

LHT:

LBD:

AGIF:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

CSET:

AGB:

LDC:

OTU:

BMOR:

BMAN:

DPL:	KGM_208368

BANY:

NIQ:

MCIX:

PMAC:

PRAP:

PBX:

PNAP:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:	114351825 114364345

CFEL:

API:

DNX:

AGS:

RMD:

HHAL:

MQU:

HAME:

Reference

PMID:1518044

Authors

Walker JE, Arizmendi JM, Dupuis A, Fearnley IM, Finel M, Medd SM, Pilkington SJ, Runswick MJ, Skehel JM

Title

Sequences of 20 subunits of NADH:ubiquinone oxidoreductase from bovine heart mitochondria. Application of a novel strategy for sequencing proteins using the polymerase chain reaction.

Journal

J Mol Biol 226:1051-72 (1992)
DOI:10.1016/0022-2836(92)91052-Q

Sequence

[bta:327690]

LinkDB

DBGET integrated database retrieval system