KEGG ORTHOLOGY: K04464

ORTHOLOGY: K04464

Entry

K04464                      KO

Symbol

MAPK7

Name

mitogen-activated protein kinase 7 [EC:2.7.11.24]

Pathway

map04010

MAPK signaling pathway

map04011

MAPK signaling pathway - yeast

map04138

Autophagy - yeast

map04139

Mitophagy - yeast

map04540

Gap junction

map04657

IL-17 signaling pathway

map04722

Neurotrophin signaling pathway

map04912

GnRH signaling pathway

map04921

Oxytocin signaling pathway

map05206

MicroRNAs in cancer

map05418

Fluid shear stress and atherosclerosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    K04464  MAPK7; mitogen-activated protein kinase 7
   04011 MAPK signaling pathway - yeast
    K04464  MAPK7; mitogen-activated protein kinase 7
09140 Cellular Processes
  09141 Transport and catabolism
   04138 Autophagy - yeast
    K04464  MAPK7; mitogen-activated protein kinase 7
   04139 Mitophagy - yeast
    K04464  MAPK7; mitogen-activated protein kinase 7
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04464  MAPK7; mitogen-activated protein kinase 7
09150 Organismal Systems
  09151 Immune system
   04657 IL-17 signaling pathway
    K04464  MAPK7; mitogen-activated protein kinase 7
  09152 Endocrine system
   04912 GnRH signaling pathway
    K04464  MAPK7; mitogen-activated protein kinase 7
   04921 Oxytocin signaling pathway
    K04464  MAPK7; mitogen-activated protein kinase 7
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    K04464  MAPK7; mitogen-activated protein kinase 7
09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    K04464  MAPK7; mitogen-activated protein kinase 7
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K04464  MAPK7; mitogen-activated protein kinase 7
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K04464  MAPK7; mitogen-activated protein kinase 7
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     K04464  MAPK7; mitogen-activated protein kinase 7
Protein kinases [BR:ko01001]
Serine/threonine kinases: CMGC group
  MAPK family [OT]
   K04464  MAPK7; mitogen-activated protein kinase 7

Other DBs

COG:

COG0515

GO:

0004707

Genes

HSA:	5598(MAPK7)

PTR:	454499(MAPK7)

PPS:	100967254(MAPK7)

GGO:	101137450(MAPK7)

PON:	100451029(MAPK7)

NLE:	100598787(MAPK7)

HMH:	116483083(MAPK7)

MCC:	702837(MAPK7)

MCF:	102133212(MAPK7)

MTHB:

126939027

MNI:	105493340(MAPK7)

CSAB:

103242509(MAPK7)

CATY:

105593716(MAPK7)

PANU:

100999653(MAPK7)

TGE:	112609132(MAPK7)

MLEU:

105552550(MAPK7)

RRO:	104660707(MAPK7)

RBB:	108516767(MAPK7)

TFN:	117067583(MAPK7)

PTEH:

111528146(MAPK7)

CANG:

105521000(MAPK7)

CJC:	100400023(MAPK7)

SBQ:	101050659(MAPK7)

CIMI:

108293479(MAPK7)

CSYR:

103273099(MAPK7)

MMUR:

105862003(MAPK7)

LCAT:

123621221(MAPK7)

PCOQ:

105816097(MAPK7)

OGA:	100962878(MAPK7)

MMU:	23939(Mapk7)

MCAL:

110305070(Mapk7)

MPAH:

110331679(Mapk7)

RNO:	114509(Mapk7)

MCOC:

116077931(Mapk7)

ANU:	117710519(Mapk7)

MUN:	110549800(Mapk7)

CGE:	100758520(Mapk7)

MAUA:

101835661(Mapk7)

PROB:

127219167(Mapk7)

PLEU:

114683277(Mapk7)

MORG:

121456806(Mapk7)

MFOT:

126514647

AAMP:

119812382(Mapk7)

NGI:	103728439(Mapk7)

HGL:	101726391(Mapk7)

CPOC:

100728396(Mapk7)

CCAN:

109699716(Mapk7)

DORD:

105985870(Mapk7)

DSP:	122103406(Mapk7)

PLOP:

125366140(Mapk7)

NCAR:

124980909

MMMA:

107157135(Mapk7)

OCU:

100338535

OPI:	101525007(MAPK7)

TUP:	102475335(MAPK7)

GVR:	103598189(MAPK7)

CFA:	489532(MAPK7)

CLUD:

112647275(MAPK7)

VVP:	112924943(MAPK7)

VLG:	121499670(MAPK7)

NPO:	129497623(MAPK7)

AML:	100470193(MAPK7)

UMR:	103658546(MAPK7)

UAH:	113271274(MAPK7)

UAR:	123779755(MAPK7)

ELK:

111139244

LLV:

125088025

MPUF:

101676890(MAPK7)

MNP:	132004382(MAPK7)

MLK:	131816173(MAPK7)

NVS:	122906879(MAPK7)

ORO:	101365927(MAPK7)

EJU:	114198222(MAPK7)

ZCA:	113908317(MAPK7)

MLX:	118000125(MAPK7)

NSU:	110584596(MAPK7)

LWW:	102729115(MAPK7)

FCA:	101097357(MAPK7)

PYU:	121015826(MAPK7)

PCOO:

112857063(MAPK7)

PBG:	122485025(MAPK7)

PVIV:

125151410(MAPK7)

LRUF:

124519580

PTG:	102964803(MAPK7)

PPAD:

109245794(MAPK7)

PUC:

125917734

AJU:

106981402

HHV:	120228757(MAPK7)

BTA:	537703(MAPK7)

BOM:	102278560(MAPK7)

BIU:	109574161(MAPK7)

BBUB:

102401035(MAPK7)

BBIS:

104990859(MAPK7)

CHX:	102180534(MAPK7)

OAS:	101110073(MAPK7)

BTAX:

128064484(MAPK7)

ODA:	120867405(MAPK7)

CCAD:

122444207(MAPK7)

MBEZ:

129544202(MAPK7)

SSC:	102164433(MAPK7)

CFR:	106728541(MAPK7)

CBAI:

105061624(MAPK7)

CDK:	105100603(MAPK7)

VPC:	102541255(MAPK7)

BACU:

102999884(MAPK7)

BMUS:

118886442(MAPK7)

LVE:	103080813(MAPK7)

OOR:	101284808(MAPK7)

DLE:	111167739(MAPK7)

PCAD:

102983466(MAPK7)

PSIU:

116745964(MAPK7)

NASI:

112405337(MAPK7)

ECB:	100073174(MAPK7)

EPZ:	103565868(MAPK7)

EAI:	106837912(MAPK7)

MYB:	102245831(MAPK7)

MYD:	102769984(MAPK7)

MMYO:

118649370(MAPK7)

MLF:	102437971(MAPK7)

PKL:	118726794(MAPK7)

EFUS:

103299365(MAPK7)

MNA:	107524519(MAPK7)

DRO:	112308530(MAPK7)

SHON:

119002719(MAPK7)

AJM:	119062269(MAPK7)

PDIC:

114515026(MAPK7)

PHAS:

123809287(MAPK7)

MMF:	118641262(MAPK7)

PPAM:

129068690(MAPK7)

HAI:	109377280(MAPK7)

RFQ:	117013633(MAPK7)

PALE:

102897014(MAPK7)

PGIG:

120589838(MAPK7)

PVP:	105291313(MAPK7)

RAY:	107511070(MAPK7)

MJV:	108409115(MAPK7)

TOD:	119231187(MAPK7)

SARA:

101541530(MAPK7)

SETR:

126013663(MAPK7)

LAV:	100671889(MAPK7)

TMU:

101346669

ETF:	101654790(MAPK7)

DNM:	101419178(MAPK7)

MDO:	100016316(MAPK7)

GAS:	123235108(MAPK7)

SHR:	100917749(MAPK7)

AFZ:

127561302

PCW:	110220473(MAPK7)

OAA:	100088657(MAPK7)

GGA:

100858386

PCOC:

116240152

MGP:	104916721(MAPK7)

CJO:	107307520(MAPK7)

NMEL:

110391499(MAPK7)

APLA:

119715311(MAPK7)

ACYG:

106029394(MAPK7)

CATA:

118261621(MAPK7)

PMOA:

120512580

PRUF:

121349796

FAB:

101806540

PHI:	102111242(MAPK7)

PMAJ:

107199450

SVG:	106863770(MAPK7)

MMEA:

130587779(MAPK7)

FPG:

101912679

NNI:	104014494(MAPK7)

AFOR:

103903861(MAPK7)

HLE:	104836865(MAPK7)

CCRI:

104159542(MAPK7)

ACAR:

104529765(MAPK7)

RTD:	128903528(MAPK7)

AROW:

112966431(MAPK7)

ASN:	102386241(MAPK7)

AMJ:	102577139(MAPK7)

PSS:	102463278(MAPK7)

CMY:	102938366(MAPK7)

CCAY:

125639095(MAPK7)

DCC:	119856779(MAPK7)

CPIC:

101932787(MAPK7)

TST:	117876618(MAPK7)

CABI:

116816166(MAPK7)

MRV:	120403296(MAPK7)

ACS:	100553854(mapk7)

ASAO:

132777726(MAPK7)

PVT:	110086378(MAPK7)

SUND:

121935390(MAPK7)

PBI:	103052089(MAPK7)

PMUR:

107290240(MAPK7)

CTIG:

120302324(MAPK7)

TSR:	106557409(MAPK7)

PGUT:

117666845(MAPK7)

APRI:

131197298(MAPK7)

PTEX:

113449965(MAPK7)

NSS:	113422517(MAPK7)

VKO:	123019595(MAPK7)

PMUA:

114582827(MAPK7)

PRAF:

128400639(MAPK7)

ZVI:	118094142(MAPK7)

HCG:	128329763(MAPK7)

GJA:	107122186(MAPK7)

STOW:

125445196(MAPK7)

EMC:	129338213(MAPK7)

XLA:	446599(mapk7.L)

XTR:	779785(mapk7)

NPR:	108800678(MAPK7)

RTEM:

120942977(MAPK7)

BBUF:

121007785(MAPK7)

BGAR:

122944495(MAPK7)

MUO:	115474613(MAPK7)

GSH:	117361200(MAPK7)

DRE:	541323(mapk7)

SRX:

SANH:

SGH:

CAUA:

CGIB:

PTET:

LROH:

127173906(mapk7)

OMC:	131551075(mapk7)

PPRM:

120468974(mapk7)

RKG:	130080592(mapk7)

MAMB:

125255330(mapk7)

CIDE:

127523710

MASI:

127422790 127427375

TROS:

130569627(mapk7)

TDW:	130438641(mapk7)

MANU:

129420705(mapk7)

IPU:

108273635

IFU:	128616920(mapk7)

PHYP:

113527556(mapk7)

SMEO:

124388748(mapk7)

TFD:	113653549(mapk7)

TVC:	132841554(mapk7)

AMEX:

103030026(mapk7)

CMAO:

118809727(mapk7)

EEE:	113591949(mapk7)

CHAR:

105892715(mapk7)

TRU:	101079574(mapk7)

TFS:	130522435(mapk7)

TNG:	GSTEN00028301G001

LCO:	104935550(mapk7)

NCC:	104967446(mapk7)

TBEN:

117473340(mapk7)

CGOB:

115024627

PGEO:

117464908(mapk7)

GACU:

117544887(mapk7)

EMAC:

134871212(mapk7)

ELY:	117246705(mapk7)

EFO:	125880839(mapk7)

PLEP:

121958387(mapk7)

SLUC:

116061553(mapk7)

ECRA:

117937273(mapk7)

ESP:	116671107(mapk7)

PFLV:

114548107(mapk7)

GAT:	120819066(mapk7)

PPUG:

119212593(mapk7)

AFB:	129091178(mapk7)

CLUM:

117748510(mapk7)

PSWI:

130203796(mapk7)

MSAM:

119915935(mapk7)

SCHU:

122867173(mapk7)

CUD:	121528202(mapk7)

ALAT:

119009758(mapk7)

MZE:	101467194(mapk7)

ONL:

102082809

OAU:	116321897(mapk7)

OLA:

101157651

OML:	112154202(mapk7)

CSAI:

133419507(mapk7)

XMA:	102229633(mapk7)

XCO:	114134421(mapk7)

XHE:	116727133(mapk7)

PRET:

103481413(mapk7)

PFOR:

103156837(mapk7)

PLAI:

106939028(mapk7)

PMEI:

106908659(mapk7)

GAF:	122823578(mapk7)

PPRL:

129377659(mapk7)

CVG:	107097215(mapk7)

CTUL:

119796752(mapk7)

GMU:	124874783(mapk7)

NFU:	107387979(mapk7)

KMR:	108237269(mapk7)

ALIM:

106521362(mapk7)

NWH:	119423971(mapk7)

AOCE:

111581585

MCEP:

125022354(mapk7)

CSEM:

103382039(mapk7)

POV:	109641502(mapk7)

SSEN:

122762753(mapk7)

HHIP:

117752778(mapk7)

HSP:	118101055(mapk7)

SMAU:

118287271(mapk7)

LCF:

108884456

SDU:	111220321(mapk7)

SLAL:

111658704

XGL:	120794867(mapk7)

HCQ:	109523949(mapk7)

SSCV:

125990903

SBIA:

133496021(mapk7)

PEE:	133417997(mapk7)

PTAO:

133469690(mapk7)

BPEC:

110159641

MALB:

109963593

BSPL:

114845515(mapk7)

SJO:	128381311(mapk7)

SASA:

106586755(mapk7)

STRU:

115161285(mapk7)

OTW:	112242455(mapk7)

OMY:	110520562(mapk7)

OGO:	124044212(mapk7)

ONE:	115113193(mapk7)

OKI:

109870513

OKE:	118366739(mapk7)

SALP:

111980038

SNH:	120058506(mapk7)

CCLU:

121536566

ELS:	105007802(mapk7)

SFM:	108941647(mapk7)

PKI:

111836823

AANG:

118220211(mapk7)

LOC:	102696491(mapk7)

PSPA:

121306863(mapk7)

PSEX:

120519620(mapk7)

LCM:	102358623(MAPK7)

RTP:	109925206(mapk7)

HOC:	132808884(mapk7)

LERI:

PMRN:

BFO:

BBEL:

CIN:	778597(erk5)

SPU:

LPIC:

APLC:

SKO:

CEL:	CELE_C04G6.1(mpk-2)

CBR:	CBG_02327(Cbr-mpk-2)

CRQ:	GCK72_005954

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MCAF:

MMER:

OBI:

OSN:

LAK:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

XEN:

HMG:

HSY:

AQU:

ATH:	AT2G46070(MPK12) AT4G11330(MPK5)

CRB:

17883824

EUS:	EUTSA_v10001502mg EUTSA_v10028737mg

BRP:	103833881 103866947

BNA:	106422273 106450856

THJ:

104817310

OSA:

4349225

DOSA:

Os10t0533600-01(Os10g0533600)

OBR:

102701584

OGL:

127752871

TAES:

123049193 123123418 123181418

TUA:

125510579

LPER:

127307179

LRD:	124706093 124706095

SBI:

ZMA:

SITA:

SVS:

PVIR:

PHAI:

SCE:	YHR030C(SLT2)

SEUB:

DI49_2436 DI49_3221

SPAO:

SPAR_H00720

AGO:	AGOS_AER232C

ERC:

Ecym_7361

KLA:	KLLA0_B11902g

KMX:	KLMA_70325(SLT2)

LTH:	KLTH0G06974g

ZRO:	ZYRO0G16082g

NCS:	NCAS_0A06680(NCAS0A06680)

NDI:	NDAI_0D01620(NDAI0D01620)

TPF:	TPHA_0B02440(TPHA0B02440)

TBL:	TBLA_0A10420(TBLA0A10420)

TGB:	HG536_0E03630

TDL:	TDEL_0E03520(TDEL0E03520)

KAF:	KAFR_0E01810(KAFR0E01810)

KNG:	KNAG_0M01450(KNAG0M01450)

ZMK:	HG535_0A04660

DHA:	DEHA2E18348g

PGU:	PGUG_01253

SPAA:

SPAPADRAFT_60035

CAL:	CAALFM_CR00120CA(MKC1)

CTP:	CTRG_01071

COT:	CORT_0A00210

CDU:	CD36_25140(MKC1)

CTEN:

CANTEDRAFT_109071

CLU:	CLUG_03997

CLUS:

A9F13_01g01254

CAUR:

CJI96_0000524

SLB:	AWJ20_17(SLT2)

PKZ:	C5L36_0B10090

BNN:	FOA43_002713(SLT2)

BBRX:

BRETT_001612(SLT2)

OPA:	HPODL_04887

SLUD:

SCDLUD_004830

MGR:

MGG_04943

TMN:	UCRPA7_297

FGR:	FGSG_10313

FPU:	FPSE_12362(MGV1)

FOX:	FOXG_05092

NHE:	NECHADRAFT_69616

TRE:	TRIREDRAFT_82351(tmk2)

MAW:

MAC_08024

MAJ:

MAA_03181

VDA:	VDAG_02584

ELA:	UCREL1_729

SSL:	SS1G_05445

BFU:	BCIN_09g02390(bmp3)

MBE:

MBM_07936

AFM:	AFUA_4G13720

ACT:	ACLA_052670

NFI:	NFIA_102670

ALUC:

AKAW2_21000S(MPK1)

ACHE:

ACHE_10418S(MPK1)

APUU:

APUU_41042A(MPK1)

PCS:	N7525_005828

PDP:	PDIP_43770

POU:	POX_a01705

TMF:	EYB26_004059

TRG:	TRUGW13939_10751

CIM:	CIMG_01981

CPW:	CPC735_045500

URE:	UREG_06906

BGH:	BDBG_04935

ARAB:

EKO05_0010440

ZTR:	MYCGRDRAFT_102121(MgSlt2)

FFU:	CLAFUR5_12136

CBET:

CB0940_12178

BCOM:

BAUCODRAFT_286788

SPO:	SPBC119.08(pmk1)

SOM:	SOMG_02281(pmk1)

CNE:

CNI00410

CNB:

CNBH0400

CNG:	CNAG_04514

CGI:	CGB_H1030C

CDEU:

CNBG_2556

TMS:	TREMEDRAFT_38101

TASA:

A1Q1_00040

CCAC:

CcaHIS019_0510880(tmk2)

» show all

Reference

PMID:7646528

Authors

Lee JD, Ulevitch RJ, Han J

Title

Primary structure of BMK1: a new mammalian map kinase.

Journal

Biochem Biophys Res Commun 213:715-24 (1995)
DOI:10.1006/bbrc.1995.2189

Sequence

[hsa:5598]

Reference

PMID:11254654

Authors

Hayashi M, Tapping RI, Chao TH, Lo JF, King CC, Yang Y, Lee JD

Title

BMK1 mediates growth factor-induced cell proliferation through direct cellular activation of serum and glucocorticoid-inducible kinase.

Journal

J Biol Chem 276:8631-4 (2001)
DOI:10.1074/jbc.C000838200

Sequence

[hsa:5598]

Reference

PMID:9111331

Authors

Watanabe Y, Takaesu G, Hagiwara M, Irie K, Matsumoto K

Title

Characterization of a serum response factor-like protein in Saccharomyces cerevisiae, Rlm1, which has transcriptional activity regulated by the Mpk1 (Slt2) mitogen-activated protein kinase pathway.

Journal

Mol Cell Biol 17:2615-23 (1997)
DOI:10.1128/MCB.17.5.2615

Sequence

[sce:YHR030C]

LinkDB

DBGET integrated database retrieval system