KEGG   ORTHOLOGY: K09637Help
Entry
K09637                      KO                                     

Name
TMPRSS6
Definition
transmembrane protease serine 6 [EC:3.4.21.-]
Disease
H01278  Iron-refractory iron deficiency anemia (IRIDA)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases
    K09637  TMPRSS6; transmembrane protease serine 6
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.-  
     K09637  TMPRSS6; transmembrane protease serine 6
Peptidases [BR:ko01002]
 Serine Peptidases
  Family S1: chymotrypsin family
   K09637  TMPRSS6; transmembrane protease serine 6
BRITE hierarchy
Genes
HSA: 164656(TMPRSS6)
PTR: 458805(TMPRSS6)
PPS: 100991084(TMPRSS6)
GGO: 101138107(TMPRSS6)
PON: 100460608(TMPRSS6)
NLE: 100581044(TMPRSS6)
MCC: 696094(TMPRSS6)
MCF: 102139590(TMPRSS6)
CSAB: 103223267(TMPRSS6)
RRO: 104682497(TMPRSS6)
RBB: 108512724(TMPRSS6)
CJC: 100394553(TMPRSS6) 100414791
SBQ: 101031384(TMPRSS6)
MMU: 71753(Tmprss6)
RNO: 315388(Tmprss6)
CGE: 100762768(Tmprss6)
NGI: 103748620(Tmprss6)
HGL: 101726737(Tmprss6)
CCAN: 109698252(Tmprss6)
TUP: 102503001(TMPRSS6)
CFA: 608593(TMPRSS6)
AML: 100468980(TMPRSS6)
UMR: 103676412(TMPRSS6)
ORO: 101387010(TMPRSS6)
FCA: 101092375(TMPRSS6)
PTG: 102962212(TMPRSS6)
AJU: 106981028(TMPRSS6)
BTA: 614844(TMPRSS6)
BOM: 102278375(TMPRSS6)
BIU: 109558530 109559532(TMPRSS6)
PHD: 102328737(TMPRSS6)
CHX: 102178888(TMPRSS6)
OAS: 101102553(TMPRSS6)
SSC: 100516673(TMPRSS6)
CFR: 102519836(TMPRSS6)
CDK: 105101577(TMPRSS6)
BACU: 103008188(TMPRSS6)
LVE: 103077358(TMPRSS6)
OOR: 101290328(TMPRSS6)
ECB: 100069647(TMPRSS6)
EPZ: 103542657(TMPRSS6)
EAI: 106837579(TMPRSS6)
MYB: 102241421(TMPRSS6)
MYD: 102752236(TMPRSS6)
HAI: 109394513(TMPRSS6)
RSS: 109439343(TMPRSS6)
PALE: 102884593(TMPRSS6) 102885180
LAV: 100669423(TMPRSS6)
TMU: 101344116
MDO: 100025330(TMPRSS6)
SHR: 100935245(TMPRSS6)
OAA: 100092848(TMPRSS6)
GGA: 418046(TMPRSS6)
MGP: 100538769(TMPRSS6)
CJO: 107313761(TMPRSS6)
APLA: 101792037(TMPRSS6)
ACYG: 106035770(TMPRSS6)
TGU: 100220511(TMPRSS6)
GFR: 102031334(TMPRSS6)
FAB: 101809510(TMPRSS6)
PHI: 102106193(TMPRSS6)
PMAJ: 107204848(TMPRSS6)
CCW: 104696291(TMPRSS6)
FPG: 101915089(TMPRSS6)
FCH: 102058575(TMPRSS6)
CLV: 102091291(TMPRSS6)
EGZ: 104134298(TMPRSS6)
AAM: 106488413(TMPRSS6)
ASN: 102377108(TMPRSS6)
AMJ: 102571953(TMPRSS6)
PSS: 102444568(TMPRSS6)
CMY: 102943942(TMPRSS6)
CPIC: 101951084(TMPRSS6)
ACS: 100560846(tmprss6) 103282443
PVT: 110075956(TMPRSS6)
PBI: 103060257(TMPRSS6)
GJA: 107123255(TMPRSS6)
XLA: 108714560(tmprss6.L) 108715798(tmprss6.S)
XTR: 100489045(tmprss6)
NPR: 108783676(TMPRSS6)
DRE: 100005420
SRX: 107705912(tmprss6) 107724765
SANH: 107673319 107676729(tmprss6)
SGH: 107554700(tmprss6) 107568369
CCAR: 109075509(tmprss6) 109106475 109113107
IPU: 108272331(tmprss6)
AMEX: 103036174(tmprss6) 111197381
TRU: 101063402(tmprss6)
LCO: 104925441(tmprss6) 109138302
NCC: 104943494(tmprss6) 104950326
MZE: 101464220(tmprss6)
OLA: 101162577(tmprss6)
XMA: 102235853(tmprss6) 111608141
PRET: 103478195(tmprss6)
NFU: 107375159(tmprss6)
CSEM: 103383424(tmprss6)
LCF: 108889055(tmprss6) 108899424
BPEC: 110157758
ELS: 105009014(tmprss6)
SFM: 108919159 108930688(tmprss6)
LCM: 102366556(TMPRSS6) 106705517
CMK: 103189770(tmprss6)
TSP: Tsp_03914
MYI: 110465206
EPA: 110253551
 » show all
TaxonomyKoalaUniProt
Reference
  Authors
Velasco G, Cal S, Quesada V, Sanchez LM, Lopez-Otin C
  Title
Matriptase-2, a membrane-bound mosaic serine proteinase predominantly expressed in human liver and showing degrading activity against extracellular matrix proteins.
  Journal
J Biol Chem 277:37637-46 (2002)
DOI:10.1074/jbc.M203007200
Reference
  Authors
Finberg KE, Heeney MM, Campagna DR, Aydinok Y, Pearson HA, Hartman KR, Mayo MM, Samuel SM, Strouse JJ, Markianos K, Andrews NC, Fleming MD
  Title
Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA).
  Journal
Nat Genet 40:569-71 (2008)
DOI:10.1038/ng.130
LinkDB All DBs

DBGET integrated database retrieval system