KEGG ORTHOLOGY: K16424

ORTHOLOGY: K16424

Entry

K16424                      KO

Symbol

dpgA

Name

3,5-dihydroxyphenylacetyl-CoA synthase [EC:2.3.1.246]

Pathway

map01055

Biosynthesis of vancomycin group antibiotics

map01110

Biosynthesis of secondary metabolites

Reaction

R06625

malonyl-CoA:malonyl-CoA malonyltransferase (3,5-dihydroxyphenylacetyl-CoA-forming)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01055 Biosynthesis of vancomycin group antibiotics
    K16424  dpgA; 3,5-dihydroxyphenylacetyl-CoA synthase
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K16424  dpgA; 3,5-dihydroxyphenylacetyl-CoA synthase
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.246  3,5-dihydroxyphenylacetyl-CoA synthase
     K16424  dpgA; 3,5-dihydroxyphenylacetyl-CoA synthase
Polyketide biosynthesis proteins [BR:ko01008]
Polyketide synthase (PKS)
  Type III PKS
   Bacterial type
    K16424  dpgA; 3,5-dihydroxyphenylacetyl-CoA synthase

Other DBs

COG:

COG3424

Genes

SMAF:

SERM:

RBAD:

XAL:

XTN:	FD63_09790

XPR:	MUG10_21500

PAND:

DRB87_09790

MNR:	ACZ75_13535

BSTO:

C0V70_02630

NBR:	O3I_032820

NTP:	CRH09_30870 CRH09_31745

NAD:	NCTC11293_04865

NIE:	KV110_15715

NGP:	LTT66_10445

SRC:	M271_00240 M271_09145

SMAL:

SSOI:

SBH:

SVE:

SCW:	TU94_04905 TU94_32245

STRC:

AA958_31865

SLE:	sle_03950(sle_03950) sle_58620(sle_58620)

STSI:

A4E84_04190

SKY:	D0C37_02210

SALW:

CP975_31980

SPHW:

NFX46_19255

SSIA:

A7J05_04090

SFK:	KY5_6273 KY5_7440

SKA:	CP970_02995 CP970_09670

SGZ:	C0216_32530

SGAL:

CP966_31750

SAQU:

EJC51_23015

STSU:

B7R87_00855

SVD:	CP969_02990

SROI:

IAG44_40635

KAU:	B6264_25030

STRH:

KFL:

NDA:

ACTW:

AGRA:

AMAZ:

NOA:	BKM31_54175

NCX:	Nocox_13295(noc8)

NGN:	LCN96_07940

FRA:	Francci3_2458

SACC:

EYD13_07740

AOI:	AORI_1502(bcsA) AORI_5330(bcsA)

AJA:	AJAP_32005

AMYB:

BKN51_41555

AAB:	A4R43_07900

AMYY:

YIM_22225

AORI:

SD37_33610

AROO:

NQK81_15375

KUT:	JJ691_30260 JJ691_70290

KBU:	Q4V64_04805

MTEM:

GCE86_08035

MSAG:

GCM10017556_56550

MFEU:

H1D33_24995(dpgA)

ACTL:

L3i22_092840(pks18)

AOU:	ACTOB_006418 ACTOB_006457

PFLA:

Pflav_008040

PSUU:

Psuf_070250

PRY:	Prubr_65020(pks18)

MPRO:

BJP34_31700

PUO:	RZN69_11825

AG:	CAC48378(dpgA)

» show all

Reference

PMID:24884615

Authors

Xu L, Huang H, Wei W, Zhong Y, Tang B, Yuan H, Zhu L, Huang W, Ge M, Yang S, Zheng H, Jiang W, Chen D, Zhao GP, Zhao W

Title

Complete genome sequence and comparative genomic analyses of the vancomycin-producing Amycolatopsis orientalis.

Journal

BMC Genomics 15:363 (2014)
DOI:10.1186/1471-2164-15-363

Sequence

[aoi:AORI_1502]

Reference

PMID:11495926

Authors

Pfeifer V, Nicholson GJ, Ries J, Recktenwald J, Schefer AB, Shawky RM, Schroder J, Wohlleben W, Pelzer S

Title

A polyketide synthase in glycopeptide biosynthesis: the biosynthesis of the non-proteinogenic amino acid (S)-3,5-dihydroxyphenylglycine.

Journal

J Biol Chem 276:38370-7 (2001)
DOI:10.1074/jbc.M106580200

Sequence

[ag:CAC48378]

LinkDB

DBGET integrated database retrieval system