KEGG   ORTHOLOGY: K22693
Entry
K22693                      KO                                     
Symbol
pyrH
Name
tryptophan 5-halogenase [EC:1.14.19.58]
Brite
KEGG Orthology (KO) [BR:ko00001]
 09190 Not Included in Pathway or Brite
  09191 Unclassified: metabolism
   99980 Enzymes with EC numbers
    K22693  pyrH; tryptophan 5-halogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.19  With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
    1.14.19.58  tryptophan 5-halogenase
     K22693  pyrH; tryptophan 5-halogenase
Other DBs
COG: COG0665
Genes
PTT: VY86_05165
PMUI: G4G71_27995
PNT: G5B91_04940
PMAZ: R5H13_18865
ENU: PYH37_005870
EGI: PZN02_006253
SGV: B1H19_08825
SPLA: CP981_21755
SMAO: CAG99_27180
AMYY: YIM_22805(rebH)
PSEQ: AD006_32380
KAL: KALB_6284
MCRA: ID554_06690
VER: HUT12_06270
NHY: JQS43_08495
COY: HF329_13070
AG: AAU95674(pyrH)
 » show all
Reference
PMID:15850981
  Authors
Zehner S, Kotzsch A, Bister B, Sussmuth RD, Mendez C, Salas JA, van Pee KH
  Title
A regioselective tryptophan 5-halogenase is involved in pyrroindomycin biosynthesis in Streptomyces rugosporus LL-42D005.
  Journal
Chem Biol 12:445-52 (2005)
DOI:10.1016/j.chembiol.2005.02.005
  Sequence
[ag:AAU95674]
Reference
PMID:19501593
  Authors
Zhu X, De Laurentis W, Leang K, Herrmann J, Ihlefeld K, van Pee KH, Naismith JH
  Title
Structural insights into regioselectivity in the enzymatic chlorination of tryptophan.
  Journal
J Mol Biol 391:74-85 (2009)
DOI:10.1016/j.jmb.2009.06.008
  Sequence
[ag:AAU95674]
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