KEGG   ORTHOLOGY: K01317
Entry
K01317                      KO                                     
Symbol
ACR
Name
acrosin [EC:3.4.21.10]
Disease
H01282  Spermatogenic failure
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K01317  ACR; acrosin
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K01317  ACR; acrosin
Enzymes [BR:ko01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.10  acrosin
     K01317  ACR; acrosin
Peptidases and inhibitors [BR:ko01002]
 Serine peptidases
  Family S1: chymotrypsin family
   K01317  ACR; acrosin
Membrane trafficking [BR:ko04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Acrosomal exocytosis proteins
    K01317  ACR; acrosin
Genes
HSA: 49(ACR)
PTR: 458950(ACR)
PPS: 100979160(ACR)
GGO: 101144239(ACR)
PON: 100448292(ACR)
PPYG: 129023123(ACR)
NLE: 100586140(ACR)
HMH: 116458999(ACR)
SSYN: 129467815(ACR)
MCC: 716579(ACR)
MCF: 102115325(ACR)
MTHB: 126964017
MNI: 105489733(ACR)
CSAB: 103223579 103223651(ACR)
TGE: 112633283(ACR)
MLEU: 105543589(ACR)
RRO: 104655563(ACR)
RBB: 108545017(ACR)
TFN: 117096242(ACR)
PTEH: 111549166(ACR)
CANG: 105512002(ACR)
CJC: 100406660(ACR)
SBQ: 101047167(ACR)
CIMI: 108286851(ACR)
ANAN: 105706695(ACR)
CSYR: 103271503(ACR)
MMUR: 105884990(ACR)
LCAT: 123640348(ACR)
PCOQ: 105813926(ACR)
OGA: 100963151(ACR)
MMU: 11434(Acr)
MCAL: 110310440(Acr)
MPAH: 110334980(Acr)
RNO: 24163(Acr)
MCOC: 116078085(Acr)
ANU: 117718981(Acr)
MUN: 110566471(Acr)
CGE: 100754856(Acr)
MAUA: 101839533(Acr)
PROB: 127225965(Acr)
PLEU: 114693039(Acr)
MORG: 121461410(Acr)
AAMP: 119823273(Acr)
NGI: 103735496(Acr)
HGL: 101712354(Acr)
CPOC: 100717414(Acr)
CCAN: 109693070(Acr)
DORD: 105992722(Acr)
NCAR: 124982996
MMMA: 107160221(Acr)
OCU: 100009184(ACR)
OPI: 101522965(ACR)
TUP: 102477933(ACR)
GVR: 103591321(ACR)
CFA: 606765(ACR)
CLUD: 112665305(ACR)
VVP: 112935879(ACR)
VLG: 121492162(ACR)
NPO: 129512087(ACR)
AML: 100482745(ACR)
UMR: 103674103(ACR)
UAH: 113241583(ACR)
UAR: 123803812(ACR)
ELK: 111157685
MPUF: 101682369(ACR)
MNP: 132020422(ACR)
MLK: 131839677(ACR)
NVS: 122891694(ACR)
ORO: 101363888 101379789(ACR)
MLX: 117997712(ACR)
NSU: 110578315(ACR)
LWW: 102727815(ACR)
FCA: 101083949(ACR)
PYU: 121040095(ACR)
PCOO: 112863376(ACR)
PBG: 122473012(ACR)
PVIV: 125170322(ACR)
LRUF: 124502535
PTG: 102954045(ACR)
PPAD: 109265792(ACR)
PUC: 125919756
AJU: 106987633
HHV: 120233554(ACR)
BTA: 280711(ACR)
BOM: 102270129(ACR)
BBUB: 102391015(ACR)
BBIS: 104980012(ACR)
CHX: 102191416(ACR)
OAS: 443195(ACR)
BTAX: 128049003(ACR)
ODA: 120857786(ACR)
CCAD: 122423039(ACR)
MBEZ: 129537237(ACR)
SSC: 397098(ACR)
CFR: 102504353(ACR)
CBAI: 105070825(ACR)
CDK: 105106149(ACR)
VPC: 102543078(ACR)
BACU: 103017313(ACR)
BMUS: 118902739(ACR)
LVE: 103072664(ACR)
OOR: 101282422(ACR)
DLE: 111186384(ACR)
PCAD: 102982720(ACR)
PSIU: 116760485(ACR)
NASI: 112394593(ACR)
ECB: 100057028(ACR)
EPZ: 103543987(ACR)
EAI: 106846026(ACR)
MYB: 102256900(ACR)
MYD: 102774021(ACR)
MMYO: 118657372(ACR)
MLF: 102426257(ACR)
PKL: 118714759(ACR)
EFUS: 103298716(ACR)
MNA: 107536030(ACR)
DRO: 112321661(ACR)
SHON: 118989694(ACR) 119003110
AJM: 119060332(ACR)
PDIC: 114496816 114513967(ACR)
PHAS: 123816028(ACR) 123831647
MMF: 118641119(ACR)
PPAM: 129068320(ACR)
HAI: 109396613(ACR)
RFQ: 117028267(ACR)
PALE: 102886339(ACR)
PGIG: 120602806(ACR)
PVP: 105308288(ACR)
RAY: 107500248(ACR)
TOD: 119248216(ACR)
SARA: 101548761(ACR)
SETR: 126006164(ACR)
LAV: 100674496(ACR)
TMU: 101350147
ETF: 101649792(ACR)
DNM: 101443016(ACR)
MDO: 103093639
GAS: 123250441(ACR)
SHR: 100916052 100932714(ACR)
GGA: 426864(ACR) 769176(ACRL)
MGP: 100539639 692129(ACR)
NMEL: 110392172(ACR) 110392173
ACYG: 106029620
FPG: 101920858
EGZ: 104122507
NNI: 104019823
PLET: 104627099
PCAO: 104050265
PADL: 103924103(ACR)
AFOR: 103893174 103895289(ACR)
HALD: 104322403(ACR)
HLE: 104833452(ACR)
MUI: 104545267
FGA: 104077990
SHAB: 115601755(ACR)
PGUU: 104460770
AAM: 106496144
SCAM: 104145754
GGN: 109292091(ACR)
CMY: 102938344(ACR)
CPIC: 101943992
TSR: 106547407
VKO: 123023716(ACR)
HCG: 128328408
GJA: 107118562(ACR) 107120174
NPR: 108802724
LCM: 102354559
HOC: 132826581
LERI: 129710807
PMAC: 106721108
NLU: 111057367
TCF: 131882068
ABRU: 129971942
HRF: 124145417
OED: 125672436
LJP: 135473810
 » show all
Reference
  Authors
Ferrer M, Rodriguez H, Zara L, Yu Y, Xu W, Oko R
  Title
MMP2 and acrosin are major proteinases associated with the inner acrosomal membrane and may cooperate in sperm penetration of the zona pellucida during fertilization.
  Journal
Cell Tissue Res 349:881-95 (2012)
DOI:10.1007/s00441-012-1429-1
Reference
PMID:2493394
  Authors
Baba T, Watanabe K, Kashiwabara S, Arai Y
  Title
Primary structure of human proacrosin deduced from its cDNA sequence.
  Journal
FEBS Lett 244:296-300 (1989)
DOI:10.1016/0014-5793(89)80549-6
  Sequence
[hsa:49]
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