KEGG   ORTHOLOGY: K08158
Entry
K08158                      KO                                     
Symbol
MDR1, FLR1, CAF5
Name
MFS transporter, DHA1 family, multidrug resistance protein
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K08158  MDR1, FLR1, CAF5; MFS transporter, DHA1 family, multidrug resistance protein
Transporters [BR:ko02000]
 Major facilitator superfamily (MFS)
  Drug transporters
   Drug:H+ antiporter-1 (12 spanner) (DHA1) family
    K08158  MDR1, FLR1, CAF5; MFS transporter, DHA1 family, multidrug resistance protein
Other DBs
COG: COG2814
TC: 2.A.1.2.6 2.A.1.2.17 2.A.1.2.35
Genes
SCE: YBR008C(FLR1)
SEUB: DI49_5177
SPAO: SPAR_B01120
LTH: KLTH0E00528g KLTH0H09856g
VPO: Kpol_1018p195 Kpol_1057p25 Kpol_358p7
ZRO: ZYRO0A13618g ZYRO0B16808g ZYRO0E09900g ZYRO0E09922g ZYRO0E09966g ZYRO0E09988g ZYRO0F04642g
CGR: CAGL0H06017g CAGL0H06039g
NCS: NCAS_0A03120(NCAS0A03120)
NDI: NDAI_0A07730(NDAI0A07730)
TPF: TPHA_0A00130(TPHA0A00130) TPHA_0I03320(TPHA0I03320) TPHA_0O02010(TPHA0O02010)
TBL: TBLA_0A04260(TBLA0A04260) TBLA_0C07220(TBLA0C07220) TBLA_0E02500(TBLA0E02500) TBLA_0E02520(TBLA0E02520)
TGB: HG536_0D06120
TDL: TDEL_0D06500(TDEL0D06500)
KAF: KAFR_0B00180(KAFR0B00180) KAFR_0D05140(KAFR0D05140) KAFR_0E00140(KAFR0E00140) KAFR_0K00100(KAFR0K00100) KAFR_0K00150(KAFR0K00150)
KNG: KNAG_0F03480(KNAG0F03480)
ZMK: HG535_0G05150
PPA: PAS_chr1-4_0431
DHA: DEHA2C17820g DEHA2D00308g DEHA2D01232g
PIC: PICST_53101(MDR17) PICST_58217(MDR12) PICST_59685(MDR11) PICST_63750(MDR16)
PGU: PGUG_01490 PGUG_03271 PGUG_03273 PGUG_03892 PGUG_04886 PGUG_04949 PGUG_05048 PGUG_05185 PGUG_05911
SPAA: SPAPADRAFT_142204 SPAPADRAFT_60428 SPAPADRAFT_61521(MDR1) SPAPADRAFT_62781
LEL: PVL30_000497(MDR1_1) PVL30_000498(MDR1_2) PVL30_002476(FLR1_1) PVL30_002477(FLR1_2) PVL30_005356(FLR1_3)
CAL: CAALFM_C603170CA(MDR1)
CTP: CTRG_02412 CTRG_03501
COT: CORT_0A05400 CORT_0A06890 CORT_0F03980
CDU: CD36_63890(MDR1)
CTEN: CANTEDRAFT_112221
YLI: YALI0C04477g YALI0C04499g YALI0C07722g YALI0F25597g
CLU: CLUG_01938
CLUS: A9F13_02g03553
CAUR: CJI96_0002498
SLB: AWJ20_1327(FLR1) AWJ20_1328(FLR1) AWJ20_3117(FLR1) AWJ20_3118(FLR1) AWJ20_4240(FLR1)
MGR: MGG_01511
PPEI: PpBr36_01029
PGRI: PgNI_03992
TMN: UCRPA7_472 UCRPA7_8280
SSCK: SPSK_08776
FGR: FGSG_02865 FGSG_05318
FPU: FPSE_05512 FPSE_07172
FPOA: FPOAC1_005223 FPOAC1_008365 FPOAC1_013217 FPOAC1_013905 FPOAC1_013958
FVN: FVRRES_05758 FVRRES_08937
FVR: FVEG_04238 FVEG_08866 FVEG_12586 FVEG_13950 FVEG_15779
FOX: FOXG_06388 FOXG_09599 FOXG_13446 FOXG_15268
NHE: NECHADRAFT_14339 NECHADRAFT_37041 NECHADRAFT_42233 NECHADRAFT_43202 NECHADRAFT_44395 NECHADRAFT_49951 NECHADRAFT_98344
FFC: NCS54_00450000 NCS54_00638200 NCS54_00768400 NCS54_00802700 NCS54_01273400
FKR: NCS57_00677200 NCS57_00808800 NCS57_00845700 NCS57_01187000 NCS57_01236000
FMU: J7337_003393 J7337_004241 J7337_010862
TRE: TRIREDRAFT_2068 TRIREDRAFT_70972 TRIREDRAFT_78585
TRR: M419DRAFT_133488 M419DRAFT_90255 M419DRAFT_98774
MAW: MAC_06009
MAJ: MAA_01141 MAA_06965
PCHM: VFPPC_00903 VFPPC_03579 VFPPC_03634 VFPPC_06481 VFPPC_14483
CMT: CCM_03001
AMUS: LMH87_001270 LMH87_006933
PLJ: VFPFJ_00707 VFPFJ_01635 VFPFJ_10078
PTKZ: JDV02_007943
CFJ: CFIO01_03103 CFIO01_06305 CFIO01_07235
CLUP: CLUP02_01351 CLUP02_17658
CHIG: CH63R_01637 CH63R_10274 CH63R_14008
PFY: PFICI_01721 PFICI_02423 PFICI_05134 PFICI_12566
SSL: SS1G_01145 SS1G_04149
BFU: BCIN_01g03400 BCIN_11g05940
MBE: MBM_02630 MBM_05792
PSCO: LY89DRAFT_442562 LY89DRAFT_606807 LY89DRAFT_632701 LY89DRAFT_689462 LY89DRAFT_691395 LY89DRAFT_697300 LY89DRAFT_725366 LY89DRAFT_765943
GLZ: GLAREA_06126 GLAREA_11503 GLAREA_12305
ACT: ACLA_016700 ACLA_061350
NFI: NFIA_057450
AOR: AO090005001365 AO090009000046 AO090012000612 AO090102000198
ANG: An03g05750 An04g10350 An08g09320 An11g08320 An11g09130 An12g04520 An12g06050 An16g02610 An18g00480 An18g01720
AFV: AFLA_002333 AFLA_004188 AFLA_011322 AFLA_011646 AFLA_012346
ALUC: AKAW2_31393A AKAW2_31593A AKAW2_50942A AKAW2_60989A(MDR1_4) AKAW2_70231A AKAW2_80759A
ACHE: ACHE_40010S ACHE_50748S
APUU: APUU_30252S APUU_40110S APUU_61197S
PCS: N7525_007876 N7525_010588 N7525_011014 N7525_011401
POU: POX_b03017
TMF: EYB26_001805
TRG: TRUGW13939_02501 TRUGW13939_08477
ABE: ARB_05855
TVE: TRV_06866
PNO: SNOG_00861(SNOG_00860) SNOG_07194 SNOG_09338
PTE: PTT_13724 PTT_16890 PTT_19768
BZE: COCCADRAFT_105388 COCCADRAFT_110310 COCCADRAFT_92762
BSC: COCSADRAFT_230135 COCSADRAFT_34378 COCSADRAFT_86538
BOR: COCMIDRAFT_2089 COCMIDRAFT_4751 COCMIDRAFT_97777
AALT: CC77DRAFT_1039356 CC77DRAFT_1066807 CC77DRAFT_134151 CC77DRAFT_61700
ARAB: EKO05_0001289 EKO05_0003037 EKO05_0004413
ZTR: MYCGRDRAFT_98719
PFJ: MYCFIDRAFT_135024 MYCFIDRAFT_138019 MYCFIDRAFT_138207 MYCFIDRAFT_27186
FFU: CLAFUR5_00717 CLAFUR5_06249
CBET: CB0940_01172 CB0940_03163 CB0940_08732 CB0940_09808
BCOM: BAUCODRAFT_120350 BAUCODRAFT_29322 BAUCODRAFT_32722
NPA: UCRNP2_10174 UCRNP2_1966
SPO: SPAC17C9.16c SPBC609.04(caf5)
SOM: SOMG_02867(mfs1) SOMG_05067
CNE: CNE01860
CNB: CNBE1830
CNG: CNAG_02363
TASA: A1Q1_04303
CCAC: CcaHIS019_0407970(MDR1)
TVS: TRAVEDRAFT_39306
DSQ: DICSQDRAFT_150218 DICSQDRAFT_179030
PCO: PHACADRAFT_111819 PHACADRAFT_203915 PHACADRAFT_208428 PHACADRAFT_208445 PHACADRAFT_211764 PHACADRAFT_213133 PHACADRAFT_84680 PHACADRAFT_93065
SHS: STEHIDRAFT_130568 STEHIDRAFT_91266 STEHIDRAFT_91329
PSQ: PUNSTDRAFT_143806 PUNSTDRAFT_67565
GTR: GLOTRDRAFT_106435 GLOTRDRAFT_115266
PCUB: JR316_0008851 JR316_0009566 JR316_0009760 JR316_0010497 JR316_0010621 JR316_0010622
MPR: MPER_10380 MPER_12882
MRR: Moror_12750 Moror_12768 Moror_985 Moror_987
MORE: E1B28_003175
SCM: SCHCO_02747523(SCHCODRAFT_02747523)
CPUT: CONPUDRAFT_109794
WSE: WALSEDRAFT_33094
UMA: UMAG_02490
PFP: PFL1_01798
SGRA: EX895_001067 EX895_004764 EX895_005764
MGL: MGL_4260
MRT: MRET_4050
 » show all
Reference
PMID:22587419
  Authors
Mandal A, Kumar A, Singh A, Lynn AM, Kapoor K, Prasad R
  Title
A key structural domain of the Candida albicans Mdr1 protein.
  Journal
Biochem J 445:313-22 (2012)
DOI:10.1042/BJ20120190
  Sequence
[cal:CAALFM_C603170CA]
Reference
PMID:9235926
  Authors
Alarco AM, Balan I, Talibi D, Mainville N, Raymond M
  Title
AP1-mediated multidrug resistance in Saccharomyces cerevisiae requires FLR1 encoding a transporter of the major facilitator superfamily.
  Journal
J Biol Chem 272:19304-13 (1997)
DOI:10.1074/jbc.272.31.19304
  Sequence
[sce:YBR008C]
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