KEGG ORTHOLOGY: K09541

ORTHOLOGY: K09541

Entry

K09541                      KO

Symbol

CRYAA

Name

crystallin, alpha A

Pathway

map04141

Protein processing in endoplasmic reticulum

Disease

H01202

Cataract

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    K09541  CRYAA; crystallin, alpha A
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts
    K09541  CRYAA; crystallin, alpha A
Chaperones and folding catalysts [BR:ko03110]
Heat shock proteins
  HSP20
   K09541  CRYAA; crystallin, alpha A

Genes

HSA:	102724652(CRYAA) 1409(CRYAA)

PTR:	458589(CRYAA)

PPS:	106634229(CRYAA)

GGO:	129529239(CRYAA)

PON:	100460863(CRYAA)

PPYG:

129022452(CRYAA)

NLE:	100599220(CRYAA)

HMH:	116482217(CRYAA)

SSYN:

129483038(CRYAA)

MCC:	722370(CRYAA)

MCF:	102145881(CRYAA)

MTHB:

126950671

MNI:	105472569(CRYAA)

CSAB:

103219534

CATY:

105575496(CRYAA)

PANU:

101006600

TGE:

112621286

MLEU:

105555553(CRYAA)

RRO:	104677995 115896204

RBB:

108529602

TFN:

117095846

PTEH:

111526514

CANG:

105520474(CRYAA)

CJC:	100384978(CRYAA)

SBQ:	101033377(CRYAA)

CIMI:

108311212(CRYAA)

ANAN:

105711916(CRYAA)

CSYR:

103273538(CRYAA)

MMUR:

105879115(CRYAA)

LCAT:

123630781(CRYAA)

PCOQ:

105822907(CRYAA)

OGA:	100949170(CRYAA)

MMU:	12954(Cryaa)

MCAL:

110283786(Cryaa)

MPAH:

110338059(Cryaa)

RNO:	24273(Cryaa)

MCOC:

116074765(Cryaa)

ANU:	117724646(Cryaa)

MUN:	110553317(Cryaa)

CGE:	100762633(Cryaa)

MAUA:

101828899(Cryaa)

PROB:

127224178(Cryaa)

PLEU:

114704004(Cryaa)

MORG:

121435563(Cryaa)

MFOT:

126501155

AAMP:

119823370(Cryaa)

NGI:	103729340(Cryaa)

HGL:	101702377(Cryaa)

CPOC:

100135506(Cryaa)

CCAN:

109675942(Cryaa)

DORD:

105993961(Cryaa)

DSP:	122114276(Cryaa)

NCAR:

124993122

MMMA:

107136517(Cryaa)

OCU:	100009294(CRYAA)

OPI:	101520527(CRYAA)

TUP:	102474117(CRYAA)

GVR:	103581256(CRYAA)

CFA:	487786(CRYAA)

CLUD:

112669186(CRYAA)

VVP:	112908028(CRYAA)

VLG:	121479513(CRYAA)

NPO:	129502153(CRYAA)

UMR:	103680761(CRYAA)

UAH:	113255668(CRYAA)

UAR:	123777492(CRYAA)

ELK:

111155751

LLV:

125078109

MPUF:

101683104(CRYAA)

MNP:	132010361(CRYAA)

MLK:	131826015(CRYAA)

NVS:	122908256(CRYAA)

ORO:	101365524(CRYAA)

EJU:	114226389(CRYAA)

ZCA:	113916784(CRYAA)

MLX:	118026918(CRYAA)

NSU:	110571117(CRYAA)

LWW:	102749029(CRYAA)

FCA:	101083874(CRYAA)

PYU:	121035892(CRYAA)

PBG:	122491125(CRYAA)

PVIV:

125159094(CRYAA)

LRUF:

124526903

PPAD:

109256962(CRYAA)

PUC:

125922057

AJU:

106985673

HHV:	120240689(CRYAA)

BTA:	281718(CRYAA)

BOM:	102286617(CRYAA)

BIU:	109560725(CRYAA)

BBUB:

102389901(CRYAA)

BBIS:

104984939(CRYAA)

CHX:	102185956(CRYAA)

OAS:	497275(CRYAA)

BTAX:

128050226(CRYAA)

ODA:	120883105(CRYAA)

CCAD:

122445390(CRYAA)

MBEZ:

129548194(CRYAA)

SSC:	110256286(CRYAA)

CFR:	102515555(CRYAA)

CBAI:

105078027(CRYAA)

CDK:	105105911(CRYAA)

VPC:	102532361(CRYAA)

BACU:

103017790(CRYAA)

BMUS:

118894585(CRYAA)

LVE:	103083387(CRYAA)

OOR:	101282191(CRYAA)

DLE:	111163873(CRYAA)

PCAD:

102983244(CRYAA)

PSIU:

116753133(CRYAA)

NASI:

112408603(CRYAA)

ECB:	100051134(CRYAA)

EPZ:

103559033

EAI:	106825307(CRYAA)

MYB:	102256892(CRYAA)

MYD:	102771958(CRYAA)

MMYO:

118676878(CRYAA)

MLF:	102431739(CRYAA)

PKL:	118723900(CRYAA)

EFUS:

103289790(CRYAA)

MNA:	107541250(CRYAA)

DRO:	112304309(CRYAA)

SHON:

118984866(CRYAA)

AJM:	119048797(CRYAA)

PDIC:

114490917(CRYAA)

PHAS:

123828020(CRYAA)

MMF:	118617477(CRYAA)

PPAM:

129072767(CRYAA)

HAI:	109395171(CRYAA)

RFQ:	117038070(CRYAA)

PALE:

102881913(CRYAA)

PGIG:

120598668(CRYAA)

PVP:	105305384(CRYAA)

RAY:	107510192(CRYAA)

MJV:	108392424(CRYAA)

SARA:

101542914(CRYAA)

LAV:	100671597(CRYAA)

TMU:

101351622

ETF:	101647981(CRYAA)

DNM:

101439298

MDO:	100014565(CRYAA)

GAS:	123239612(CRYAA)

SHR:	100934164(CRYAA)

AFZ:

127553797

PCW:	110199081 110199127(CRYAA)

TVP:	118839867(CRYAA)

OAA:	791110(CRYAA)

GGA:	418546(CRYAA)

PCOC:

116229881(CRYAA)

MGP:	100551348(CRYAA)

CJO:	107323949(CRYAA)

TPAI:

128076505(CRYAA)

LMUT:

125698148(CRYAA)

NMEL:

110403502(CRYAA)

APLA:

101798865(CRYAA)

ACYG:

106036148(CRYAA)

CATA:

118247686(CRYAA)

AFUL:

116499677(CRYAA)

TGU:	100223182(CRYAA)

LSR:	110479434 110479438

SCAN:

103815756(CRYAA)

PMOA:

120511837(CRYAA)

OTC:	121333492(CRYAA)

PRUF:

121364519(CRYAA)

GFR:	102033292(CRYAA)

FAB:	101820380(CRYAA)

OMA:	130260163(CRYAA)

PHI:	102106939(CRYAA)

PMAJ:

107200024(CRYAA)

CCAE:

111927737(CRYAA) 111943342

CCW:	104686255(CRYAA)

CBRC:

103614842(CRYAA)

ETL:	114072565(CRYAA)

ZAB:	102069769(CRYAA)

ZLE:	135442859(CRYAA)

ACHL:

103797900

SVG:	106853486(CRYAA)

MMEA:

130581029(CRYAA)

HRT:	120749032(CRYAA)

FPG:	101910671(CRYAA)

FCH:	102052369(CRYAA)

CLV:	102086709(CRYAA)

EGZ:	104128198(CRYAA)

NNI:	104020849(CRYAA)

PCRI:

PLET:

EHS:

PCAO:

ACUN:

113480305(CRYAA)

TALA:

104369071(CRYAA)

PADL:

103920303(CRYAA)

AFOR:

103902019(CRYAA)

ACHC:

115344141(CRYAA)

HLE:	104839773(CRYAA)

AGEN:

GCL:

CCRI:

CSTI:

CMAC:

MUI:

BREG:

FGA:

GSTE:

LDI:

MNB:

OHA:	104327741(CRYAA)

NNT:

104409197

SHAB:

115603890(CRYAA)

DPUB:

104305008(CRYAA)

PGUU:

104465945

ACAR:

104526802

CPEA:

104388988(CRYAA)

AVIT:

104271597

CVF:	104292034(CRYAA)

RTD:	128917822(CRYAA)

CUCA:

104059244(CRYAA)

TEO:

104382200

BRHI:

104496803

AAM:	106483659(CRYAA)

AROW:

112968446(CRYAA)

NPD:	112944687(CRYAA)

TGT:	104579752(CRYAA)

DNE:	112981959(CRYAA)

SCAM:

104147116(CRYAA)

ASN:	102380355(CRYAA)

AMJ:	102575594(CRYAA)

CPOO:

109305866(CRYAA)

GGN:	109303318(CRYAA)

PSS:	102445289(CRYAA)

CMY:	102933278(CRYAA)

CCAY:

125643132(CRYAA)

DCC:	119862932(CRYAA)

CPIC:

101954150(CRYAA)

CABI:

116830582(CRYAA) 116831949

MRV:	120372132(CRYAA)

ACS:	100555261(cryaa)

ASAO:

132770007(CRYAA)

PVT:	110074089(CRYAA)

SUND:

121927301(CRYAA)

PBI:

103056412

PMUR:

107295079

CTIG:

120319620(CRYAA)

TSR:

106542858

PGUT:

117669450(CRYAA)

APRI:

131199862(CRYAA)

PTEX:

113444736(CRYAA)

NSS:	113416251(CRYAA)

VKO:	123029403(CRYAA)

PMUA:

114596128(CRYAA)

PRAF:

128413060(CRYAA)

ZVI:	118085239(CRYAA)

HCG:	128349765(CRYAA)

GJA:	107109229(CRYAA)

STOW:

125430769(CRYAA)

EMC:	129326456(CRYAA)

XLA:	108707790 378668(cryaa.S)

XTR:	100488185(cryaa)

NPR:

108803609

RTEM:

120924197

BBUF:

120993157(CRYAA)

BGAR:

122922926 122933083

DRE:	100000769(cryaa)

SRX:	107712549 107742640

SANH:

107654264 107667665

SGH:	107552378 107588844

CCAR:

109048103 109075799

CAUA:

113044367(cryaa) 113058390

CGIB:

127949665 128015399

PTET:

122349392(cryaa)

LROH:

127171305(cryaa)

OMC:	131544617(cryaa)

PPRM:

120488658(cryaa)

RKG:	130087818(cryaa)

MAMB:

125272309(cryaa)

CIDE:

127514712

MASI:

127443744

IPU:

108258320

IFU:	128601988(cryaa)

PHYP:

113537588(cryaa)

SMEO:

124378183(cryaa)

TFD:	113648849(cryaa)

TVC:	132839397(cryaa)

TRN:	134329290(cryaa)

AMEX:

103026914(cryaa)

CMAO:

118797904(cryaa)

EEE:	113578516(cryaa)

CHAR:

122131720(cryaa)

TRU:

101064246

TFS:	130522732(cryaa)

TNG:	GSTEN00027051G001 GSTEN00034201G001

LCO:

104937049

NCC:

104954342

TBEN:

117477445(cryaa)

CGOB:

115020544(cryaa)

PGEO:

117459048(cryaa)

GACU:

117539368(cryaa)

EMAC:

134861101(cryaa)

ELY:	117250140(cryaa)

EFO:	125885167(cryaa)

PLEP:

121963013(cryaa)

SLUC:

116051809(cryaa)

ECRA:

117939538(cryaa)

ESP:	116673713(cryaa)

PFLV:

114551186(cryaa)

GAT:	120822778(cryaa)

PPUG:

119216212(cryaa)

AFB:	129111943(cryaa)

CLUM:

117744995(cryaa)

MSAM:

119900762(cryaa)

SCHU:

122872081(cryaa)

CUD:	121506441(cryaa)

ALAT:

119015363(cryaa)

MZE:

101471510

ONL:	100694893(cryaa)

OAU:	116332527(cryaa)

OLA:	100049490(cryaa)

OML:	112142004(cryaa)

CSAI:

133425275(cryaa)

XMA:	102221741 102222412 102225424 102230834(cryaa)

XCO:	114140288(cryaa) 114149036 114149037 114149207 114149210 114149859 114149915 114150101

XHE:	116715557(cryaa)

PRET:

103473547 103477197(cryaa)

PFOR:

103149040

PLAI:

106939151

PMEI:

106909875

GAF:	122827008(cryaa)

PPRL:

129378788(cryaa)

CVG:	107104861(cryaa)

CTUL:

119772551(cryaa)

GMU:	124861207(cryaa)

NFU:	107373011 107374875 107384540 107395369 107395379 107396533 107396827

KMR:	108241839(cryaa) 108241933(hspb6)

ALIM:

106513603 106535347

NWH:	119429149(cryaa)

AOCE:

111577104(hspb6) 111582387(cryaa)

MCEP:

125000964(cryaa)

CSEM:

103388512(hspb6) 103389259

POV:	109639046(cryaa)

SSEN:

122783966(cryaa)

HHIP:

117772329(cryaa)

HSP:	118103482(cryaa)

PPLT:

128431152(cryaa)

SMAU:

118304569(cryaa)

LCF:	108890637 108902548(cryaa)

SDU:

111233288

SLAL:

111670304(cryaa)

XGL:	120798226(cryaa)

HCQ:	109514771(cryaa)

SSCV:

125989113

SBIA:

133509396(cryaa)

PEE:	133409497(cryaa)

PTAO:

133483435(cryaa)

BPEC:

110171826(hspb6) 110175637(cryaa)

BSPL:

114851016(cryaa)

SJO:	128354353(cryaa)

SASA:

106574754 106575746

STRU:

115180876 115182129

OTW:	112242113 112267643

OMY:	110495380 110495501

OGO:	124010497(cryaa)

OKI:	109888237 109890507

OKE:	118382449(cryaa)

SALP:

112077334(cryaa)

SNH:	120050580 120050584

CCLU:

121573039(cryaa)

ELS:	105031004(cryaa)

SFM:	108920039 108933129(cryaa)

PKI:	111843684 111853127(cryaa)

AANG:

118214152 118223379(cryaa)

LOC:	102691439(cryaa)

PSPA:

121321306(cryaa) 121328118

ARUT:

117406390(cryaa)

LCM:	102364354(CRYAA)

CMK:	103188729(cryaa)

RTP:	125484434(cryaa)

CPLA:

122555446(cryaa)

HOC:	132821228(cryaa)

LERI:

129703090(cryaa)

APLC:

AAG:

HST:

TCA:

AGRG:

AGB:

PPYR:

DPL:	KGM_205547

MCIX:

HAW:

TNL:

SLIU:

OFU:

PGW:

ACOO:

HHAL:

HVI:

MQU:	128983983 128988323 128989116 129005139

IEL:

124165032

FCD:	110843290 110858817 110860920

DMK:	116920153 116920156

PVM:	113825278 113825287 113825290 113825298 113825304 113825320

PJA:	122264757 122264929 122264930

LSM:

121117835

DSV:	119432905 119432906 119437709 119449061

RSAN:

119401621

RMP:	119160749 119169952

TUT:

107371183

DFR:	124491789 124496463

CSCU:

111621582

UDV:

129221555

SDM:

118181083

NAI:	NECAME_01752 NECAME_17791 NECAME_18935

PCAN:

PMAX:

ADF:

HSY:

Reference

PMID:10217480

Authors

Derham BK, Harding JJ

Title

Alpha-crystallin as a molecular chaperone.

Journal

Prog Retin Eye Res 18:463-509 (1999)
DOI:10.1016/S1350-9462(98)00030-5

Reference

PMID:22120592

Authors

Nagaraj RH, Nahomi RB, Shanthakumar S, Linetsky M, Padmanabha S, Pasupuleti N, Wang B, Santhoshkumar P, Panda AK, Biswas A

Title

Acetylation of alphaA-crystallin in the human lens: effects on structure and chaperone function.

Journal

Biochim Biophys Acta 1822:120-9 (2012)
DOI:10.1016/j.bbadis.2011.11.011

Sequence

[hsa:1409 102724652]

LinkDB

DBGET integrated database retrieval system