KEGG ORTHOLOGY: K13047

ORTHOLOGY: K13047

Entry

K13047                      KO

Symbol

TLL2

Name

tolloid-like protein 2 [EC:3.4.24.-]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K13047  TLL2; tolloid-like protein 2
Peptidases and inhibitors [BR:ko01002]
Metallo peptidases
  Family M12: astacin/adamalysin family
   K13047  TLL2; tolloid-like protein 2

Genes

HSA:	7093(TLL2)

PTR:	450644(TLL2)

PPS:	100977512(TLL2)

GGO:	101143649(TLL2)

PON:	100457372(TLL2)

NLE:	100581412(TLL2)

HMH:	116456733(TLL2)

MCC:	705290(TLL2)

MCF:	102143479(TLL2)

MTHB:

126962067

MNI:	105478457(TLL2)

CSAB:

103216322(TLL2)

CATY:

105581781(TLL2)

PANU:

101006900(TLL2)

TGE:	112631580(TLL2)

MLEU:

105554011(TLL2)

RRO:	104682826(TLL2)

RBB:	108534539(TLL2)

TFN:	117069296(TLL2)

PTEH:

111538685(TLL2)

CANG:

105518283(TLL2)

CJC:	100405295(TLL2)

SBQ:	101032459(TLL2)

CIMI:

108285527(TLL2)

CSYR:

103261495(TLL2)

MMUR:

105872880(TLL2)

LCAT:

123650188(TLL2)

PCOQ:

105818483(TLL2)

OGA:	100962972(TLL2)

MMU:	24087(Tll2)

MCAL:

110285712(Tll2)

MPAH:

110327642(Tll2)

RNO:	365460(Tll2)

MCOC:

116103824(Tll2)

ANU:	117718566(Tll2)

MUN:	110546316(Tll2)

CGE:	100756031(Tll2)

MAUA:

101826742(Tll2)

PROB:

127233537(Tll2)

PLEU:

114706882(Tll2)

MORG:

121454452(Tll2)

MFOT:

126506248

AAMP:

119825979(Tll2)

NGI:	103733212(Tll2)

HGL:	101713756(Tll2)

CPOC:

100713528(Tll2)

DORD:

105986564(Tll2)

DSP:	122115807(Tll2)

PLOP:

125346215(Tll2)

NCAR:

124985118

MMMA:

107149755(Tll2)

OCU:

108178406

OPI:	101522029(TLL2)

TUP:	102478657(TLL2)

GVR:	103592580(TLL2)

CFA:	486816(TLL2)

CLUD:

112672119(TLL2)

VVP:	112934321(TLL2)

VLG:	121477945(TLL2)

NPO:	129493743(TLL2)

AML:	100480828(TLL2)

UMR:	103658792(TLL2)

UAH:	113251770(TLL2)

UAR:	123784000(TLL2)

ELK:

111145202

LLV:

125085238

MPUF:

101677739(TLL2)

MNP:	132015346(TLL2)

MLK:	131828598(TLL2)

NVS:	122898987(TLL2)

ORO:	101367679(TLL2)

EJU:	114205459(TLL2)

ZCA:	113923884(TLL2)

MLX:	118024302(TLL2)

NSU:	110589324(TLL2)

LWW:	102740586(TLL2)

FCA:	101086678(TLL2)

PYU:	121037049(TLL2)

PCOO:

112854328(TLL2)

PBG:	122493074(TLL2)

PVIV:

125148391(TLL2)

LRUF:

124506704

PTG:	102951264(TLL2)

PPAD:

109272694(TLL2)

PUC:

125933409

AJU:

106984795

HHV:	120230622(TLL2)

BTA:	504975(TLL2)

BOM:	102273427(TLL2)

BIU:	109553220(TLL2)

BBUB:

102404854(TLL2)

BBIS:

104983549(TLL2)

CHX:	102172596(TLL2)

OAS:	101107749(TLL2)

BTAX:

128067840(TLL2)

ODA:	120873743(TLL2)

CCAD:

122446020(TLL2)

MBEZ:

129555505(TLL2)

SSC:	100157589(TLL2)

CFR:	102508880(TLL2)

CBAI:

105081791(TLL2)

CDK:	105084273(TLL2)

VPC:	102525310(TLL2)

BACU:

103010890(TLL2)

BMUS:

118882704(TLL2)

LVE:	103082214(TLL2)

OOR:	101287885(TLL2)

DLE:	111172630(TLL2)

PCAD:

102994745(TLL2)

PSIU:

116741624(TLL2)

NASI:

112393016(TLL2)

ECB:	100070823(TLL2)

EPZ:	103552066(TLL2)

EAI:	106842099(TLL2)

MYB:	102239075(TLL2)

MYD:	102768401(TLL2)

MMYO:

118670243(TLL2)

MLF:	102434612(TLL2)

PKL:	118719338(TLL2)

EFUS:

103288432(TLL2)

MNA:	107542513(TLL2)

DRO:	112307100(TLL2)

SHON:

118990316(TLL2)

AJM:	119044514(TLL2)

PDIC:

114497300(TLL2)

PHAS:

123828924(TLL2)

MMF:	118632426(TLL2)

PPAM:

129077270(TLL2)

HAI:	109380923(TLL2)

RFQ:	117035765(TLL2)

PALE:

102888304(TLL2)

PGIG:

120609259(TLL2)

PVP:	105301400(TLL2)

RAY:	107520377(TLL2)

MJV:	108399663(TLL2)

TOD:	119234267(TLL2)

SARA:

101551062(TLL2)

SETR:

126033808(TLL2)

LAV:	100673280(TLL2)

TMU:

101350012

ETF:	101655845(TLL2)

DNM:	101443483(TLL2)

MDO:	100022570(TLL2)

GAS:	123236342(TLL2)

SHR:	100935078(TLL2)

AFZ:

127546941

PCW:	110215524(TLL2)

OAA:	100086650(TLL2)

GGA:	107053676(TLL2)

PCOC:

116234490(TLL2)

MGP:	100550155(TLL2)

CJO:	107315909(TLL2)

TPAI:

128077565(TLL2)

LMUT:

125694062(TLL2)

NMEL:

110399445(TLL2)

APLA:

101799805

ACYG:

106029930(TLL2)

CATA:

118245647(TLL2)

AFUL:

116491300 116491639

TGU:	100224187(TLL2)

LSR:	110480290(TLL2)

SCAN:

103814199(TLL2)

PMOA:

120502195(TLL2)

OTC:	121341920(TLL2)

PRUF:

121350341(TLL2)

GFR:	102036572(TLL2)

FAB:	101814476(TLL2)

OMA:	130255090(TLL2)

PHI:	102109528(TLL2)

PMAJ:

107207027(TLL2)

CCAE:

111930906(TLL2)

CCW:	104697942(TLL2)

CBRC:

103624582(TLL2)

ETL:	114065367(TLL2)

ZAB:	102070989(TLL2)

ACHL:

103799015

SVG:	106855360(TLL2)

MMEA:

130578805(TLL2)

HRT:	120755746(TLL2)

FPG:	101911625(TLL2)

FCH:	102049130(TLL2)

CLV:	102095313(TLL2)

EGZ:	104129017(TLL2)

NNI:	104020623(TLL2)

PCRI:

PLET:

EHS:

PCAO:

ACUN:

113481646(TLL2)

TALA:

104363793(TLL2)

PADL:

103915606(TLL2)

AFOR:

103897812(TLL2)

ACHC:

115348493(TLL2)

HALD:

104315631

HLE:	104831980(TLL2)

AGEN:

GCL:

CCRI:

CSTI:

CMAC:

MUI:

BREG:

FGA:

GSTE:

LDI:

MNB:

OHA:	104334260(TLL2)

NNT:

104407128

SHAB:

115608211(TLL2)

DPUB:

104297764(TLL2)

PGUU:

104467275

ACAR:

104527148

CPEA:

104391501(TLL2)

AVIT:

104273143

CVF:	104289821(TLL2)

RTD:	128911349(TLL2)

CUCA:

104067984(TLL2)

TEO:	104384466(TLL2)

BRHI:

104492084

AAM:	106498873(TLL2)

AROW:

112967515

NPD:	112956885(TLL2)

TGT:	104573054(TLL2)

DNE:	112980236(TLL2)

SCAM:

104141788(TLL2)

ASN:	102374850(TLL2)

AMJ:	102564211(TLL2)

CPOO:

109323861(TLL2)

GGN:	109287139(TLL2)

PSS:	102462488(TLL2)

CMY:	102944578(TLL2)

CCAY:

125640333(TLL2)

DCC:	119858549(TLL2)

CPIC:

101933393(TLL2)

TST:	117880740(TLL2)

CABI:

116823589(TLL2)

MRV:	120369298(TLL2)

XLA:	399469(tll2.L)

NPR:

108802275

RTEM:

120947171(TLL2)

BBUF:

121004991(TLL2)

BGAR:

LOC:

PSPA:

ARUT:

PSEX:

LCM:	102346034(TLL2)

CMK:

HOC:

LERI:

PMRN:

LRJ:	133350659 133356271

BFO:	118410730 118411735

BBEL:

109475490 109480574 109485505

CIN:	778782(tolloid)

SCLV:

120347058

SPU:	105438784 593453 593467 593502 593517(SpAN)

LPIC:

129281507

AJC:

117117482

SKO:	100369209 100375661

CNS:	116347255 116348636

FVI:

DPZ:

PVM:

PJA:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

LSM:

TCF:

PPOI:

PMEO:

PCAN:

OED:

MYI:

MCAF:

LAK:	106151305 106176846

NVE:

116604499

EPA:	110241920 110249280

ATEN:

116307846

AMIL:

114951456 114962289

PDAM:

113676665 113680620

SPIS:

111326096 111329147 111333256 111334319

XEN:

HMG:

HSY:

Reference

PMID:10479448

Authors

Scott IC, Blitz IL, Pappano WN, Imamura Y, Clark TG, Steiglitz BM, Thomas CL, Maas SA, Takahara K, Cho KW, Greenspan DS

Title

Mammalian BMP-1/Tolloid-related metalloproteinases, including novel family member mammalian Tolloid-like 2, have differential enzymatic activities and distributions of expression relevant to patterning and skeletogenesis.

Journal

Dev Biol 213:283-300 (1999)
DOI:10.1006/dbio.1999.9383

Sequence

[hsa:7093] [mmu:24087]

Reference

PMID:9520331

Authors

Goodman SA, Albano R, Wardle FC, Matthews G, Tannahill D, Dale L

Title

BMP1-related metalloproteinases promote the development of ventral mesoderm in early Xenopus embryos.

Journal

Dev Biol 195:144-57 (1998)
DOI:10.1006/dbio.1997.8840

Sequence

[xla:399469]

LinkDB

DBGET integrated database retrieval system