KEGG ORTHOLOGY: K16308

ORTHOLOGY: K16308

Entry

K16308                      KO

Symbol

CIT

Name

citron Rho-interacting kinase [EC:2.7.11.35]

Disease

H00269

Primary microcephaly

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K16308  CIT; citron Rho-interacting kinase
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.35  CRIK-subfamily protein kinase
     K16308  CIT; citron Rho-interacting kinase
Protein kinases [BR:ko01001]
Serine/threonine kinases: AGC group
  DMPK family [OT]
   K16308  CIT; citron Rho-interacting kinase

Genes

HSA:	11113(CIT)

PTR:	108449892(CIT)

PPS:	100974320(CIT)

GGO:	101126596(CIT)

PON:	100443427(CIT)

NLE:	100602938(CIT)

HMH:	116477839(CIT)

MCC:	695846(CIT)

MCF:	102134813(CIT)

MTHB:

126930592

MNI:	105494878(CIT)

CSAB:

103239239(CIT)

CATY:

105590927 105592760

PANU:

101001804(CIT)

TGE:	112634123(CIT)

MLEU:

105527998(CIT)

RRO:	104666242(CIT)

RBB:	108534016(CIT)

TFN:	117089312(CIT)

PTEH:

111537603(CIT)

CANG:

105502312(CIT)

CJC:	100403341(CIT)

SBQ:	101028521(CIT)

CIMI:

108290416(CIT)

CSYR:

103271804(CIT)

MMUR:

105866902(CIT)

LCAT:

123625946(CIT)

PCOQ:

105815034(CIT)

OGA:	100943449(CIT)

MMU:	12704(Cit)

MCAL:

110294017(Cit)

MPAH:

110339063(Cit)

RNO:	83620(Cit)

MCOC:

116068262(Cit)

ANU:	117697845(Cit)

MUN:	110545579(Cit)

CGE:	100755517(Cit)

MAUA:

101828040(Cit)

PROB:

127216000(Cit)

PLEU:

114682615(Cit)

MORG:

121445302(Cit)

MFOT:

126511684

AAMP:

119824753(Cit)

NGI:	103726787(Cit)

HGL:	101704993(Cit)

CPOC:

100731607(Cit)

CCAN:

109696173(Cit)

DORD:

105984216(Cit)

DSP:	122099063(Cit)

PLOP:

125349065(Cit)

NCAR:

124990232

MMMA:

107158708(Cit)

OCU:

100348177

OPI:	101524442(CIT)

TUP:	102503389(CIT)

GVR:

103602791

CFA:	100683247(CIT)

CLUD:

112676654(CIT)

VVP:	112932903(CIT)

VLG:	121475813(CIT)

NPO:	129508023(CIT)

AML:	100484860(CIT)

UMR:	103678331(CIT)

UAH:	113267030(CIT)

UAR:	123788292(CIT)

ELK:

111156397

LLV:

125081897

MPUF:

101672603(CIT)

MNP:	132023219(CIT)

MLK:	131810834(CIT)

NVS:	122903370(CIT)

ORO:	101371655(CIT)

EJU:	114219010(CIT)

ZCA:	113912850(CIT)

MLX:	118018533(CIT)

NSU:	110592587(CIT)

LWW:	102742304(CIT)

FCA:	101094297(CIT)

PYU:	121010244(CIT)

PCOO:

112870093(CIT)

PBG:	122470292(CIT)

PVIV:

125148620(CIT)

LRUF:

124518201

PTG:	102951229(CIT)

PPAD:

109277548(CIT)

PUC:

125914111

AJU:

106971699

HHV:	120237108(CIT)

BTA:	786852(CIT)

BOM:	102277777(CIT)

BIU:	109570918(CIT)

BBUB:

102391447(CIT)

BBIS:

104989651(CIT)

CHX:	106503032(CIT)

OAS:	101107309(CIT)

BTAX:

128062364(CIT)

ODA:	120871109(CIT)

CCAD:

122423376(CIT)

MBEZ:

129542599(CIT)

SSC:	100153706(CIT)

CFR:	102509956(CIT)

CBAI:

105080696(CIT)

CDK:	105104899(CIT)

VPC:	102544945(CIT)

BACU:

103014319(CIT)

BMUS:

118906830(CIT)

LVE:	103087503(CIT)

OOR:	101288927(CIT)

DLE:	111187014(CIT)

PCAD:

102994078(CIT)

PSIU:

116765055(CIT)

NASI:

112408756(CIT)

ECB:	100050621(CIT)

EPZ:	103540685(CIT)

EAI:	106844779(CIT)

MYB:	102256469(CIT)

MYD:	102769046(CIT)

MMYO:

118678170(CIT)

MLF:	102429617(CIT)

PKL:	118725278(CIT)

EFUS:

103287097(CIT)

MNA:	107528510(CIT)

DRO:	112310585(CIT)

SHON:

118991165(CIT)

AJM:	119057435(CIT)

PDIC:

114509073(CIT)

PHAS:

123821530(CIT)

MMF:	118639821(CIT)

PPAM:

129087512(CIT)

HAI:	109386167(CIT)

RFQ:	117017504(CIT)

PALE:

102887573(CIT)

PGIG:

120606776(CIT)

PVP:	105289404(CIT)

RAY:	107513173(CIT)

MJV:	108408199(CIT)

TOD:	119244922(CIT)

SARA:

101538728(CIT)

SETR:

126029506(CIT)

LAV:	100676080(CIT)

TMU:

101360937

ETF:	101657631(CIT)

DNM:	101412801(CIT)

MDO:	100014244(CIT)

GAS:	123232401(CIT)

SHR:	100919480(CIT)

AFZ:

127545542

PCW:	110222808(CIT)

OAA:	100090847(CIT)

GGA:	416984(CIT)

PCOC:

116228409(CIT)

MGP:	100544730(CIT)

CJO:	107321392(CIT)

TPAI:

128083991(CIT)

LMUT:

125701714(CIT)

NMEL:

110406384(CIT)

APLA:

101800393(CIT)

ACYG:

106031450(CIT)

CATA:

118252941(CIT)

AFUL:

116496332(CIT)

TGU:	100217966(CIT)

LSR:	110481336(CIT)

SCAN:

103818045(CIT)

PMOA:

120510263(CIT)

OTC:	121344502(CIT)

PRUF:

121364879(CIT)

GFR:	102031443(CIT)

FAB:	101806903(CIT)

OMA:	130259642(CIT)

PHI:	102108518(CIT)

PMAJ:

107211648(CIT)

CCAE:

111936586(CIT)

CCW:	104688532(CIT)

CBRC:

103622658(CIT)

ETL:	114056604(CIT)

ZAB:	102075425(CIT)

ACHL:

103809015(CIT)

SVG:	106864892(CIT)

MMEA:

130578242(CIT)

HRT:	120760440(CIT)

FPG:	101919237(CIT)

FCH:	102057372(CIT)

CLV:	102096644(CIT)

EGZ:	104129860(CIT)

NNI:	104011510(CIT)

PCRI:

104036970

PLET:

104618847(CIT)

EHS:	104507850(CIT)

PCAO:

104044168(CIT)

ACUN:

113485958(CIT)

TALA:

104363379(CIT)

PADL:

103922640(CIT)

AFOR:

103905768(CIT)

ACHC:

115345478(CIT)

HALD:

104310516(CIT)

HLE:	104836111(CIT)

AGEN:

126040770

GCL:

127022831

CCRI:

104161135(CIT)

CSTI:

104549295(CIT)

CMAC:

104480519(CIT)

MUI:	104539707(CIT)

BREG:

104640678(CIT)

FGA:	104079649(CIT)

GSTE:

104264632(CIT)

LDI:	104343831(CIT)

MNB:	103781152(CIT)

OHA:	104331426(CIT)

NNT:	104409890(CIT)

SHAB:

115614544(CIT)

DPUB:

104308443(CIT)

PGUU:

104464295(CIT)

ACAR:

104517844(CIT)

CPEA:

104395155(CIT)

AVIT:

104267436(CIT)

CVF:	104289630(CIT)

RTD:	128916931(CIT)

CUCA:

104064245(CIT)

TEO:	104380048(CIT)

BRHI:

104492430(CIT)

AAM:	106486313(CIT)

AROW:

112970621(CIT)

NPD:	112946092(CIT)

TGT:	104577597(CIT)

DNE:	112994586(CIT)

SCAM:

104152228(CIT)

ASN:	102382644(CIT)

AMJ:	102568242(CIT)

CPOO:

109312890(CIT)

GGN:	109290329(CIT)

PSS:	102460121(CIT)

CMY:	102931126(CIT)

CCAY:

125622723(CIT)

DCC:	119843977(CIT)

CPIC:

101943175(CIT)

TST:	117888102(CIT)

CABI:

116825799(CIT)

MRV:	120386457(CIT)

ACS:	100553665(cit)

ASAO:

132781279(CIT)

PVT:	110088951(CIT)

SUND:

121916575(CIT)

PBI:	103056658(CIT)

PMUR:

107288823(CIT)

CTIG:

120303214(CIT)

TSR:	106542252(CIT)

PGUT:

117659632(CIT)

APRI:

131185624(CIT)

PTEX:

113448067(CIT)

NSS:	113423291(CIT)

VKO:	123032753(CIT)

PMUA:

114586916(CIT)

PRAF:

128404224(CIT)

ZVI:	118076464(CIT)

HCG:	128337774(CIT)

GJA:	107122282(CIT)

STOW:

125443169(CIT)

EMC:	129341200(CIT)

XLA:	108705103(cit.S) 108715932(cit.L)

XTR:	100145758(cit)

NPR:	108800405(CIT)

RTEM:

120937347(CIT)

BBUF:

120988806(CIT)

BGAR:

122924383(CIT)

MUO:	115479578(CIT)

GSH:	117365770(CIT)

DRE:	100329792(cita) 100333880

SRX:	107715152 107734412 107743069 107754418

SANH:

107670977 107687252 107691162 107699660

SGH:	107552141 107553025 107567946 107574082

CCAR:

109069686 109072217 109090071

CAUA:

113052782 113070138 113070868 113106944

CGIB:

127957140 127962977 128014912 128019027

PTET:

122344687(cita) 122350791

LROH:

127165410(cita) 127170111

OMC:	131540701(cita) 131546195

PPRM:

120471630(cita) 120489872

RKG:	130091481 130101106(cita)

MAMB:

125266222(cita) 125279925

CIDE:

127512724 127513163 127517054

MASI:

127414519 127423095 127423772 127433126

TROS:

130564055(cita) 130568621

TDW:	130419282(cita) 130440175

MANU:

129413699 129439557(cita)

IPU:	108260404(cita) 108265536

IFU:	128603896(cita) 128607739

PHYP:

113524481 113531312(cit)

SMEO:

124378993(cita) 124400374

TFD:	113637250(cita) 113656231

TVC:	132840782(cita) 132853504

AMEX:

103030651 103047007(cit)

CMAO:

118813483 118814677(cita)

EEE:	113571046 113577578(cit)

CHAR:

105891590 105902547(cita)

TRU:	101069918 101072584

TFS:	130524325(cita) 130525251

TNG:	GSTEN00021610G001

LCO:	104926380 104927949

NCC:	104965599(cit)

TBEN:

117484802 117486539(cita)

CGOB:

115008192 115014036

PGEO:

117446721(cita)

GACU:

117549778 117561897(cita)

EMAC:

134873388 134883509(cita)

ELY:	117252643 117256877(cita)

EFO:	125890345 125892702(cita)

PLEP:

121944223 121954307(cita)

SLUC:

116034270(cita) 116051665

ECRA:

117943539(cita) 117944657

ESP:	116686666 116687376(cit) 116689313

PFLV:

114554226 114555336

GAT:	120831368 120835061(cita)

PPUG:

119225527 119229853(cita)

AFB:	129101587 129105707(cita)

CLUM:

117730341(cita) 117735874

PSWI:

130191261(cita) 130197410

MSAM:

119886342(cita) 119891669

SCHU:

122868949(cita) 122877040

CUD:	121506887(cita) 121509871

ALAT:

119020180 119021298(cita)

MZE:	101480054 101482388

ONL:	100702904 100706533

OAU:	116322686 116326534(cita)

OLA:	101155268 101170523

OML:	112145776(cita) 112148858

CSAI:

133448843(cita) 133451438

XMA:	102221046 102221896

XCO:	114135492 114154421

XHE:	116710560 116729353

PRET:

103464971 103469600

PFOR:

103139608 103152408

PLAI:

106937497 106956973(cit)

PMEI:

106906974 106927803(cit)

GAF:	122828829 122834447(cita)

PPRL:

129358358(cita) 129373068

CVG:	107093676 107097289(cit) 107099985 107102941

CTUL:

119780129 119781506

GMU:	124856815(cita) 124878458

NFU:	107385498(cit) 107393501

KMR:	108235002 108239854(cita)

ALIM:

106518397(cit) 106529463

NWH:	119412222(cita)

AOCE:

111567175 111577860

MCEP:

125007096(citA) 125012713

CSEM:

103386221(cit) 103397033 103397430

POV:	109629236 109633620

SSEN:

122767929(cita) 122769936

HHIP:

117761188(cita) 117768391

HSP:	118105202(cita) 118114794

SMAU:

118309239(cita) 118313825

LCF:	108878264 108899696

SDU:	111221856 111231034

SLAL:

111647956 111670956

XGL:	120783165 120804987

HCQ:	109522556 109524982

SSCV:

125977048 125993685

SBIA:

133500014 133507676(cita)

PEE:	133400345 133408433

PTAO:

133474737 133483809(cita)

BPEC:

110163324(cit) 110166199

MALB:

109955924 109959669

BSPL:

114855586(cita) 114862007

SJO:	128355219(cita) 128364974

SASA:

106565373 106579949 106583567 106585475

STRU:

115150381 115164658 115199975 115208046

OTW:	112215505(cita) 112249482 112254787 112263040

OMY:	110494113(cita) 110525124 110528298 110535055

OGO:	124003058(cita) 124019314 124034412 124036192

ONE:	115111488 115139923 115141829 115143003

OKI:	109878325 109891598 109893847 109895792

OKE:	118357844 118388750(cita) 118394047

SALP:

111964570 111975037

SNH:	120062259 120062619(cita) 120063159

CCLU:

121550488 121575090(cita) 121577763 121584738

ELS:	105014195 105017043(cit)

SFM:	108921854 108931971

PKI:	111842090(cit) 111858763

AANG:

118206623 118212598

LOC:	102688934(cit)

PSPA:

121297104 121299813

ARUT:

117426735 117427900

PSEX:

120540680(cita)

LCM:	102350303(CIT)

CMK:

103189866

RTP:	109931848(cita)

CPLA:

122562422(cita)

HOC:	132827181(cita)

LERI:

129709113(cita)

PMRN:

116939138(CIT)

LRJ:	133348451(CIT)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

AJC:

SKO:

DME:	Dmel_CG10522(sti)

DER:

6545306

DSI:	Dsimw501_GD12711(Dsim_GD12711)

DYA:	Dyak_GE20113

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI13065

DAZ:

DNV:

DHE:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ016714 CpipJ_CPIJ018912

CPII:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

OBB:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

CGLO:

FAS:

AGIF:

VCAN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_206900

MJU:

VCD:

MCIX:

PPOT:

PXU:

PRAP:

ZCE:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:	105384047 105394822

PGW:

CCRN:

API:

AGS:

RMD:

DCI:

PHU:	Phum_PHUM573900

FOC:

TPAL:

ZNE:

CSEC:

IEL:

FCD:

DPX:	DAPPUDRAFT_229061

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

CSCU:

PTEP:

ABRU:

UDV:

LPOL:

LGI:	LOTGIDRAFT_53739

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CANU:

OED:

MYI:

PMAX:

MMER:

RPHI:

OBI:

OSN:

LAK:

SMM:	Smp_148690

SHX:	MS3_00001977

OVI:	T265_02569

EGL:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

TAD:	TRIADDRAFT_27610 TRIADDRAFT_27763

MBR:	MONBRDRAFT_11201

» show all

Reference

PMID:21849473

Authors

Gai M, Camera P, Dema A, Bianchi F, Berto G, Scarpa E, Germena G, Di Cunto F

Title

Citron kinase controls abscission through RhoA and anillin.

Journal

Mol Biol Cell 22:3768-78 (2011)
DOI:10.1091/mbc.E10-12-0952

Sequence

[hsa:11113]

Reference

PMID:21457715

Authors

Tan I, Lai J, Yong J, Li SF, Leung T

Title

Chelerythrine perturbs lamellar actomyosin filaments by selective inhibition of myotonic dystrophy kinase-related Cdc42-binding kinase.

Journal

FEBS Lett 585:1260-8 (2011)
DOI:10.1016/j.febslet.2011.03.054

Sequence

[hsa:11113]

LinkDB

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