KEGG ORTHOLOGY: K19520

ORTHOLOGY: K19520

Entry

K19520                      KO

Symbol

UPK3A, UPIII

Name

uroplakin-3a

Pathway

map05219

Bladder cancer

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09162 Cancer: specific types
   05219 Bladder cancer
    K19520  UPK3A, UPIII; uroplakin-3a
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K19520  UPK3A, UPIII; uroplakin-3a
Exosome [BR:ko04147]
Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K19520  UPK3A, UPIII; uroplakin-3a

Genes

HSA:	7380(UPK3A)

PTR:	458905(UPK3A)

PPS:	100980017(UPK3A)

GGO:	101138849(UPK3A)

PON:	100447798(UPK3A)

PPYG:

129023227(UPK3A)

NLE:	105740017(UPK3A)

HMH:

116464913

SSYN:

129468505(UPK3A)

MCC:	717456(UPK3A)

MCF:	102140464(UPK3A)

MTHB:

126963635

MNI:	105464289(UPK3A)

CSAB:

103223470(UPK3A)

CATY:

105586930(UPK3A)

PANU:

101006683(UPK3A)

TGE:	112633407(UPK3A)

MLEU:

105542488(UPK3A)

RRO:	104665946(UPK3A)

RBB:	108514490(UPK3A)

TFN:	117096719(UPK3A)

PTEH:

111549161

CANG:

105506567(UPK3A)

CJC:	100411003(UPK3A)

SBQ:	101047271(UPK3A)

CIMI:

108304942(UPK3A)

ANAN:

105715232(UPK3A)

CSYR:

103257463(UPK3A)

MMUR:

105867630(UPK3A)

LCAT:

123640355(UPK3A)

PCOQ:

105822741(UPK3A)

OGA:	100945209(UPK3A)

MMU:	22270(Upk3a)

MCAL:

110310977(Upk3a)

MPAH:

110335222(Upk3a)

RNO:	315190(Upk3a)

MCOC:

116081712(Upk3a)

ANU:	117719145(Upk3a)

ASYL:

127667617(Upk3a)

MUN:	110545040(Upk3a)

CGE:

113833532

MAUA:

101826340(Upk3a)

PROB:

127225568(Upk3a)

PLEU:

114699177(Upk3a)

MORG:

121461530(Upk3a)

MFOT:

126491963

AAMP:

119824002(Upk3a)

NGI:	103743422(Upk3a)

HGL:	101700751(Upk3a)

CPOC:

100720560(Upk3a)

CCAN:

109688844(Upk3a)

DORD:

106001982(Upk3a)

DSP:	122102165(Upk3a)

DMER:

138822001 138822158

PLOP:

125357267(Upk3a)

NCAR:

124983637

MMMA:

107155777(Upk3a)

ITI:	101968363(Upk3a)

OCU:

100358839

OPI:	101528886(UPK3A)

TUP:	102468856(UPK3A)

GVR:	103598721 103598723(UPK3A)

CFA:	609118(UPK3A)

CLUD:

112674956(UPK3A)

VVP:	112934042(UPK3A)

VLG:	121492050(UPK3A)

NPO:	129511926(UPK3A)

AML:	100472623(UPK3A)

UMR:	103674034(UPK3A)

UAR:	123780723(UPK3A)

ELK:

111157691

LLV:

125106403

MPUF:

101676575(UPK3A)

MNP:	132020431(UPK3A)

MLK:	131839607(UPK3A)

NVS:	122891332(UPK3A)

ORO:	101363305(UPK3A)

EJU:	114218513(UPK3A)

ZCA:	113922836(UPK3A)

MLX:	117998494(UPK3A)

NSU:	110578282(UPK3A)

LWW:	102745636(UPK3A)

FCA:	101088858(UPK3A)

PYU:	121040186(UPK3A)

PCOO:

112863406(UPK3A)

PBG:	122472895(UPK3A)

PVIV:

125170288(UPK3A)

LRUF:

124502463

LGF:	123590941(UPK3A)

AJU:

106967312

PTG:	102958581(UPK3A)

PPAD:

109265713(UPK3A)

PUC:

125919697

PLEZ:

122223760(UPK3A)

HHV:	120235338(UPK3A)

BTA:	100336102(UPK3A)

BOM:	102286006(UPK3A)

BIU:	109558855(UPK3A)

BBUB:

102404342(UPK3A)

BBIS:

104986897(UPK3A)

CHX:	102177602(UPK3A)

OAS:	101119631(UPK3A)

BTAX:

128047591(UPK3A)

CSUM:

138079257(UPK3A)

ODA:	120858478(UPK3A)

CCAD:

122423694(UPK3A)

MREE:

136160515(UPK3A)

OVR:	110134031(UPK3A)

MBEZ:

129536804(UPK3A)

SSC:	397558(UPK3A)

CFR:	102515728(UPK3A)

CBAI:

105073027(UPK3A)

CDK:	105091847(UPK3A)

VPC:	102528649(UPK3A)

BACU:

103020646(UPK3A)

BMUS:

118902591(UPK3A)

LVE:	103086069(UPK3A)

OOR:	101281183(UPK3A)

LALB:

132529355(UPK3A)

GMF:	115852524(UPK3A)

DDP:	132433373(UPK3A)

DLE:	111186414(UPK3A)

PCAD:

102982786(UPK3A)

PSIU:

116760751(UPK3A)

PPHC:

136131166(UPK3A)

NASI:

112394696(UPK3A)

ECB:	100052016(UPK3A)

EPZ:	103566702(UPK3A)

EAI:	106845966(UPK3A)

MYB:	102258613(UPK3A)

MYD:	102755702(UPK3A)

MMYO:

118652156(UPK3A)

MLF:	102434458(UPK3A)

MDT:	132225983(UPK3A)

MYUM:

139005814(UPK3A)

PKL:	118708778(UPK3A)

EFUS:

103298684(UPK3A)

MNA:	107534843(UPK3A)

DRO:	112322074(UPK3A)

SHON:

118989723(UPK3A)

AJM:	119060464(UPK3A)

PDIC:

114513951(UPK3A)

PHAS:

123816187(UPK3A)

MMF:	118641157(UPK3A)

PPAM:

129077967(UPK3A)

HAI:	109387609(UPK3A)

RFQ:	117028721(UPK3A)

PALE:

102879181(UPK3A)

PGIG:

120602775(UPK3A)

PVP:	105302038(UPK3A)

RAY:	107505525(UPK3A)

MJV:	108400523(UPK3A)

TOD:	119248228(UPK3A)

SARA:

101550337(UPK3A)

SFUM:

130016352(UPK3A)

SETR:

126006307(UPK3A)

LAV:	100658957 100659478(UPK3A)

TMU:

101347177

ETF:	101663587(UPK3A)

DNM:	101422952(UPK3A)

MDO:	100028394(UPK3A)

GAS:	123249508(UPK3A)

SHR:	100922486(UPK3A)

AFZ:

127538989

PCW:	110201650(UPK3A)

TVP:	118850002(UPK3A)

PBRV:

138173595(UPK3A)

MLAO:

141515581(UPK3A)

OAA:	100080347(UPK3A)

TACU:

119937258(UPK3A)

GGA:	418242(UPK3A)

PCOC:

116231398(UPK3A)

MGP:	100542508(UPK3A)

CJO:	107317561(UPK3A)

TPAI:

128084505(UPK3A)

LMUT:

125690662(UPK3A)

NMEL:

110392446(UPK3A)

APLA:

101795143(UPK3A)

ACYG:

106038296(UPK3A)

CATA:

118250167(UPK3A)

AFUL:

116502310(UPK3A)

CBRC:

108445761(UPK3A)

ACOE:

138104483(UPK3A)

ETL:	114070056(UPK3A)

FPG:	101922255(UPK3A)

FCH:	102052432(UPK3A)

CCRI:

104166787(UPK3A)

NNT:	104406848(UPK3A)

SHAB:

115605588(UPK3A)

ACUN:

113491341(UPK3A)

TALA:

104363200(UPK3A)

ACHC:

115352841(UPK3A)

HALD:

104315093(UPK3A)

HLE:	104836713(UPK3A)

AGEN:

126047626

HHAR:

128143506(UPK3A)

GCL:

127022073

CSTI:

104554585(UPK3A)

LDI:	104346920(UPK3A)

MNB:	103778010(UPK3A)

AVIT:

104278107(UPK3A)

EGZ:	104135109(UPK3A)

NNI:	104012716(UPK3A)

PCRI:

104033496(UPK3A)

PCAO:

104048496(UPK3A)

PADL:

103916634(UPK3A)

AFOR:

103902581(UPK3A)

FGA:	104075867(UPK3A)

GSTE:

104262523(UPK3A)

CBOY:

140646378(UPK3A)

CLV:	102087775(UPK3A)

CNIC:

136003171(UPK3A)

MUI:	104538013(UPK3A)

PGUU:

104469829(UPK3A)

PLET:

104625767(UPK3A)

CMAC:

104480957(UPK3A)

CUCA:

104062829(UPK3A)

TEO:	104380359(UPK3A)

BREG:

104638547(UPK3A)

OHA:	104334105(UPK3A)

ACAR:

104525156(UPK3A)

CPEA:

104393513(UPK3A)

CVF:	104281738(UPK3A)

RTD:	128902641(UPK3A)

CRID:

134509911(UPK3A)

AAM:	106488421(UPK3A)

AROW:

112977647(UPK3A)

NPD:	112956859(UPK3A)

TGT:	104564701(UPK3A)

DNE:	112991559(UPK3A)

SCAM:

104146671(UPK3A)

ASN:	102375002(UPK3A)

AMJ:	102573492(UPK3A)

CPOO:

109316333(UPK3A)

GGN:	109296510(UPK3A)

PSS:	102447845(UPK3A)

CMY:	102937645(UPK3A)

CCAY:

125624307(UPK3A)

DCC:	119850221(UPK3A)

CPIC:

101945577(UPK3A)

TST:	117870784(UPK3A)

CABI:

116823483(UPK3A)

MRV:	120380917(UPK3A)

ACS:	103278944(upk3a)

ASAO:

132775422(UPK3A)

PVT:	110084552 110084554(UPK3A)

SUND:

121931570(UPK3A)

PBI:

112541352

PMUR:

114923105

PGUT:

117678866

VKO:	123033930(UPK3A)

PMUA:

114596688(UPK3A) 114596863

PRAF:

128413372(UPK3A)

ZVI:	118096527 118096528(UPK3A)

HCG:	128327498(UPK3A)

GJA:

107122543

STOW:

125443624(UPK3A)

EMC:	129344246(UPK3A)

XLA:	398743(upk3a.L)

XTR:	394575(upk3a)

NPR:	108800621(UPK3A)

RTEM:

120932930(UPK3A)

ACAT:

141132924(UPK3A)

BBUF:

120986955(UPK3A)

BGAR:

122926470(UPK3A)

DTC:	141083421(UPK3A)

PWL:	138287651(UPK3A)

MUO:	115477603(UPK3A)

GSH:	117363628(UPK3A)

LOC:	107078059(upk3a) 107078082

PSPA:

121318577

ARUT:

117420039

LCM:	106703061(UPK3A)

CMK:

CPLA:

HOC:

LERI:

HAKA:

PMRN:

116940016(UPK3A) 116944567 116956492 116956515

LRJ:	133340994 133350210(UPK3A) 133360365 133360422

» show all

Reference

PMID:19412341

Authors

Thumbikat P, Berry RE, Zhou G, Billips BK, Yaggie RE, Zaichuk T, Sun TT, Schaeffer AJ, Klumpp DJ

Title

Bacteria-induced uroplakin signaling mediates bladder response to infection.

Journal

PLoS Pathog 5:e1000415 (2009)
DOI:10.1371/journal.ppat.1000415

Sequence

[hsa:7380]

Reference

PMID:23213380

Authors

Kihira S, Yoshida J, Kawada Y, Hitomi Y, Asada T, Hisatomi R, Ohta A, Iwasaki T, Mahbub Hasan AK, Fukami Y, Sato K

Title

Membrane microdomain-associated uroplakin IIIa contributes to Src-dependent mechanisms of anti-apoptotic proliferation in human bladder carcinoma cells.

Journal

Biol Open 1:1024-34 (2012)
DOI:10.1242/bio.20121115

LinkDB

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