Klebsiella pneumoniae PMK1: PMK1_02138
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Entry
PMK1_02138 CDS
T03419
Symbol
iolA
Name
(GenBank) Methylmalonate semialdehyde dehydrogenase [acylating]
KO
K00140
malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:
1.2.1.18
1.2.1.27
]
Organism
kpx
Klebsiella pneumoniae PMK1
Pathway
kpx00280
Valine, leucine and isoleucine degradation
kpx00410
beta-Alanine metabolism
kpx00562
Inositol phosphate metabolism
kpx00640
Propanoate metabolism
kpx01100
Metabolic pathways
kpx01200
Carbon metabolism
Brite
KEGG Orthology (KO) [BR:
kpx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
PMK1_02138 (iolA)
00562 Inositol phosphate metabolism
PMK1_02138 (iolA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
PMK1_02138 (iolA)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
PMK1_02138 (iolA)
Enzymes [BR:
kpx01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
PMK1_02138 (iolA)
1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
PMK1_02138 (iolA)
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Gene cluster
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Motif
Pfam:
Aldedh
LuxC
DUF6237
Motif
Other DBs
NCBI-ProteinID:
AIT01608
UniProt:
A0A060VJ39
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Position
2300797..2302302
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AA seq
501 aa
AA seq
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MTITGNFIGGKTVISSSNETMPVYDPATGKAVREVTVSTAQEVSEAIQVARDAFDSWSRT
TPLRRARVLFNFKMLLEQHVEELAGIIVSEHGKVWSDALGELTRGMEVVEFACGIPHLIK
GEYSSDVGTGVDSYSLMQPLGVVAGITPFNFPAMVPMWMFPLALACGNSFVLKPPALAPT
AAVRLAELLKEAGLPDGVFNVVHCSNEDAEQLYTDPRIAAVSFVGSSGVAEYIYKTASAH
GKRVQAFGAAKNHAIVMPDADLDATVNAIMGGAFGSAGERCMALPVVVAVGDETADKLIA
RLKPLVEALKVGPGCMRGQEENEMGPVVSDTHQKKVLGYIDKGESEGAKLVVDGRKLRVP
GYDAGYYVGGTLFDHVTPEMTIWREEIFGPVLGIVRAADYDSALELVNSHEFGNGSAVFT
SNGHTAREFVHDVQAGMVGVNVPVPVPMAFHSFGGWKRSVFGALNVHGPDGVRFYTRMKT
ATVRWPAGQQTVSEFSMPTLG
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atgacgatcacaggaaactttattggcgggaaaaccgttatcagcagcagcaacgaaacg
atgccggtgtacgacccggcgacgggcaaagcggtgcgcgaagtcacggtgtcaaccgcg
caggaagtctccgaggcgattcaggttgctcgcgatgcgtttgacagttggtcccgtacc
acgccgctgcgccgcgcccgcgtgctgttcaacttcaaaatgttgctggagcagcacgtg
gaagagctggcggggatcatcgtcagcgagcacggtaaggtgtggtcggatgcgctgggc
gagctgacccgcggtatggaagtggtcgaattcgcctgcgggatcccgcacctgattaaa
ggcgaatactcctctgacgtcggcaccggcgtcgacagctactcgctgatgcagcccctg
ggcgtggtggcagggatcaccccgtttaacttcccggcgatggtgccgatgtggatgttc
ccgctggcgctggcctgcggcaacagtttcgtcctcaagccgcccgcgctggcgccgacg
gccgctgtgcgtctggcagagctgttaaaagaggctggtctaccggacggcgtgtttaac
gtcgtgcactgcagcaatgaagatgccgagcagctgtacactgacccgcgtattgcggcg
gtgagcttcgtcggctcctccggcgtggcggagtatatctataagaccgccagcgcccac
ggcaagcgagtgcaggccttcggcgccgccaaaaaccacgcgattgtgatgccggatgcc
gatctcgacgccaccgttaacgccattatgggcggcgcttttggctccgcaggcgagcgc
tgcatggcgctgccggtggtggtggcggtgggagatgaaaccgccgacaaactgatcgcc
cgcctgaagccgctggtggaagcgctgaaagtaggcccgggctgcatgcgtggtcaggaa
gagaacgagatgggaccggtggtgtctgatacccaccagaaaaaagtgctcggctatatt
gataaaggcgaaagcgaaggggcaaaactggtggtcgatggccgcaaactgcgcgtgccg
ggttacgacgcgggctactatgtcggcggcaccctgttcgatcacgtcaccccggagatg
accatctggcgcgaagagatctttggcccggtgctggggattgtgcgcgcggcggactat
gacagcgcccttgagctggtcaacagccacgagtttggcaacggcagcgccgttttcacc
agcaacggccacaccgcgcgtgaattcgtccacgacgtgcaggcggggatggtcggggtg
aacgtgccggtcccggtgccgatggcgttccacagcttcggcggctggaagcgctcggtg
tttggcgcgttgaacgtccacgggccggacggcgtgcgcttctacacgcgtatgaagacc
gccaccgtacgctggccggcagggcagcagaccgtatctgaattcagcatgccgacgtta
ggttaa
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